Planaria EST Database


DrC_00790

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00790
         (509 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9Z0J0|NPC2_MOUSE  Epididymal secretory protein E1 precur...    85   1e-16
sp|O97763|NPC2_PIG  Epididymal secretory protein E1 precurso...    84   2e-16
sp|P61917|NPC2_PANTR  Epididymal secretory protein E1 precur...    83   3e-16
sp|P79345|NPC2_BOVIN  Epididymal secretory protein E1 precur...    82   6e-16
sp|Q9DGJ3|NPC2_BRARE  Epididymal secretory protein E1 precur...    77   3e-14
sp|Q28895|NPC2_CANFA  Epididymal secretory protein E1 precur...    68   1e-11
sp|Q9VQ62|NPC2_DROME  Hypothetical protein NPC2 precursor (N...    67   2e-11
sp|Q25481|ES16_MANSE  Ecdysteroid regulated 16 kDa protein p...    55   7e-08
sp|P27236|DCP_SALTY  Peptidyl-dipeptidase dcp (Dipeptidyl ca...    29   5.6  
sp|Q25158|OPSC2_HEMSA  Compound eye opsin BCRH2                    29   7.3  
>sp|Q9Z0J0|NPC2_MOUSE Epididymal secretory protein E1 precursor (Niemann Pick type C2
           protein homolog) (mE1)
          Length = 149

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 43/143 (30%), Positives = 68/143 (47%)
 Frame = +1

Query: 10  ILGLSFINISLTEPTIYKDCGSKKGIVQSVEITPCSTQPCQLKKGTKPQITIKYKSNENX 189
           IL L+ +  S  EP  +KDCGSK G+++ V ++PC T PCQL KG    + I + S    
Sbjct: 8   ILLLALVAASQAEPLHFKDCGSKVGVIKEVNVSPCPTDPCQLHKGQSYSVNITFTSGTQS 67

Query: 190 XXXXXXXXXXXXIFNLPFSLPDNDLXXXXXXXXXXXXQTNSTYTNSIDILKYYPSVRVTI 369
                          +PF +P+ D             +  S Y N + +   YPS+++ +
Sbjct: 68  QNSTALVHGILEGIRVPFPIPEPDGCKSGINCPIQKDKVYS-YLNKLPVKNEYPSIKLVV 126

Query: 370 TWELIDADGNDIVCVQMPTSIVS 438
            W+L D   N++ C ++P  I S
Sbjct: 127 EWKLEDDKKNNLFCWEIPVQITS 149
>sp|O97763|NPC2_PIG Epididymal secretory protein E1 precursor (Niemann Pick type C2
           protein homolog) (16 kDa secretory protein)
          Length = 149

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 42/134 (31%), Positives = 64/134 (47%)
 Frame = +1

Query: 37  SLTEPTIYKDCGSKKGIVQSVEITPCSTQPCQLKKGTKPQITIKYKSNENXXXXXXXXXX 216
           +L EP  ++DCGS  G+++ V + PC TQPCQL KG    + + + SN            
Sbjct: 17  ALAEPVHFRDCGSGVGVIKEVNVNPCPTQPCQLHKGQSYSVNVTFTSNTQSKGSKAVVHG 76

Query: 217 XXXIFNLPFSLPDNDLXXXXXXXXXXXXQTNSTYTNSIDILKYYPSVRVTITWELIDADG 396
                 +PF +PD D             QT S Y N + +   YPS+++ + W+L D + 
Sbjct: 77  IVMGVPIPFPIPDPDGCKSGINCPIQKDQTYS-YLNKLPVKAEYPSIKLVVEWKLQDDND 135

Query: 397 NDIVCVQMPTSIVS 438
             + C Q+P  I S
Sbjct: 136 QCLFCWQIPVQIES 149
>sp|P61917|NPC2_PANTR Epididymal secretory protein E1 precursor (Niemann Pick type C2
           protein homolog) (EPI-1)
 sp|P61918|NPC2_MACFA Epididymal secretory protein E1 precursor (Niemann Pick type C2
           protein homolog) (Epididymal secretory protein 14.6)
           (ESP14.6)
 sp|P61916|NPC2_HUMAN Epididymal secretory protein E1 precursor (Niemann-Pick disease
           type C2 protein) (hE1)
          Length = 151

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 41/140 (29%), Positives = 66/140 (47%)
 Frame = +1

Query: 19  LSFINISLTEPTIYKDCGSKKGIVQSVEITPCSTQPCQLKKGTKPQITIKYKSNENXXXX 198
           L+    +  EP  +KDCGS  G+++ V ++PC TQPCQL KG    + + + SN      
Sbjct: 11  LALSTAAQAEPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVTFTSNIQSKSS 70

Query: 199 XXXXXXXXXIFNLPFSLPDNDLXXXXXXXXXXXXQTNSTYTNSIDILKYYPSVRVTITWE 378
                       +PF +P+ D             +T S Y N + +   YPS+++ + W+
Sbjct: 71  KAVVHGILMGVPVPFPIPEPDGCKSGINCPIQKDKTYS-YLNKLPVKSEYPSIKLVVEWQ 129

Query: 379 LIDADGNDIVCVQMPTSIVS 438
           L D     + C ++P  IVS
Sbjct: 130 LQDDKNQSLFCWEIPVQIVS 149
>sp|P79345|NPC2_BOVIN Epididymal secretory protein E1 precursor (Niemann Pick type C2
           protein homolog) (EPV20)
          Length = 149

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 40/143 (27%), Positives = 67/143 (46%)
 Frame = +1

Query: 4   IVILGLSFINISLTEPTIYKDCGSKKGIVQSVEITPCSTQPCQLKKGTKPQITIKYKSNE 183
           +  L L+    +L EP  +KDCGS  G+++ V ++PC TQPC+L +G    + + + SN 
Sbjct: 6   VAFLFLALSASALAEPVKFKDCGSWVGVIKEVNVSPCPTQPCKLHRGQSYSVNVTFTSNT 65

Query: 184 NXXXXXXXXXXXXXIFNLPFSLPDNDLXXXXXXXXXXXXQTNSTYTNSIDILKYYPSVRV 363
                            +PF +P++D             +T + Y N + +   YPS++V
Sbjct: 66  QSQSSKAVVHGIVMGIPVPFPIPESDGCKSGIRCPIEKDKTYN-YVNKLPVKNEYPSIKV 124

Query: 364 TITWELIDADGNDIVCVQMPTSI 432
            + WEL D       C Q+P  +
Sbjct: 125 VVEWELTDDKNQRFFCWQIPIEV 147
>sp|Q9DGJ3|NPC2_BRARE Epididymal secretory protein E1 precursor (Niemann Pick type C2
           protein homolog) (16.5 kDa secretory protein)
          Length = 149

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 40/140 (28%), Positives = 62/140 (44%)
 Frame = +1

Query: 19  LSFINISLTEPTIYKDCGSKKGIVQSVEITPCSTQPCQLKKGTKPQITIKYKSNENXXXX 198
           LSF+  +  +P  + DCGS  G V  V+I PCS QPC+L KG    + + + S       
Sbjct: 11  LSFLAYTCADPVKFVDCGSVDGKVVQVDIKPCSQQPCKLHKGQSYTVNVTFSSGVESQTS 70

Query: 199 XXXXXXXXXIFNLPFSLPDNDLXXXXXXXXXXXXQTNSTYTNSIDILKYYPSVRVTITWE 378
                       +PF +P +D             Q    Y   + +   YP+++V + WE
Sbjct: 71  KAVVHGVLAGVPVPFPIPIDD-GCKSGIQCPIVPQKPYNYVTELPVKTEYPAIKVVVEWE 129

Query: 379 LIDADGNDIVCVQMPTSIVS 438
           L D    D+ C++ P  IV+
Sbjct: 130 LRDDSSKDLFCIKFPVQIVN 149
>sp|Q28895|NPC2_CANFA Epididymal secretory protein E1 precursor (Niemann Pick type C2
           protein homolog) (cE1)
          Length = 149

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 32/125 (25%), Positives = 57/125 (45%)
 Frame = +1

Query: 58  YKDCGSKKGIVQSVEITPCSTQPCQLKKGTKPQITIKYKSNENXXXXXXXXXXXXXIFNL 237
           +KDCGS  G+++ + + PC  QPC+L KG    + + + SN                  +
Sbjct: 24  FKDCGSAVGVIKELNVNPCPAQPCKLHKGQSYSVNVTFTSNIPSQSSKAVVHGIVLGVAV 83

Query: 238 PFSLPDNDLXXXXXXXXXXXXQTNSTYTNSIDILKYYPSVRVTITWELIDADGNDIVCVQ 417
           PF +P+ D             +T S Y N + +   YPS+++ + W L+  +   + C +
Sbjct: 84  PFPIPEADGCKSGINCPIQKDKTYS-YLNKLPVKNEYPSIKLVVQWMLLGDNNQHLFCWE 142

Query: 418 MPTSI 432
           +P  I
Sbjct: 143 IPVQI 147
>sp|Q9VQ62|NPC2_DROME Hypothetical protein NPC2 precursor (Niemann Pick type C2 protein
           homolog)
          Length = 148

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 39/127 (30%), Positives = 54/127 (42%), Gaps = 2/127 (1%)
 Frame = +1

Query: 58  YKDCGSKKGIVQSVEITPCSTQP--CQLKKGTKPQITIKYKSNENXXXXXXXXXXXXXIF 231
           + DCGSK G    V I  C T    C LK+ T    +I +   E                
Sbjct: 21  FSDCGSKTGKFTRVAIEGCDTTKAECILKRNTTVSFSIDFALAEEATAVKTVVHGKVLGI 80

Query: 232 NLPFSLPDNDLXXXXXXXXXXXXQTNSTYTNSIDILKYYPSVRVTITWELIDADGNDIVC 411
            +PF L + D               +  YT ++ +L+ YP V V + WEL D DG DI+C
Sbjct: 81  EMPFPLANPDACVDSGLKCPLEKDESYRYTATLPVLRSYPKVSVLVKWELQDQDGADIIC 140

Query: 412 VQMPTSI 432
           V++P  I
Sbjct: 141 VEIPAKI 147
>sp|Q25481|ES16_MANSE Ecdysteroid regulated 16 kDa protein precursor
          Length = 145

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 2/127 (1%)
 Frame = +1

Query: 58  YKDCGSKKGIVQSVEIT--PCSTQPCQLKKGTKPQITIKYKSNENXXXXXXXXXXXXXIF 231
           Y DCGSK   VQSV ++  P + + C LK+ +   I+I +    +               
Sbjct: 19  YTDCGSKLATVQSVGVSGWPENARECVLKRNSNVTISIDFSPTTDVSAITTEVHGVIMSL 78

Query: 232 NLPFSLPDNDLXXXXXXXXXXXXQTNSTYTNSIDILKYYPSVRVTITWELIDADGNDIVC 411
            +PF     D                + Y  ++ +LK YP V V + WEL   D  D+VC
Sbjct: 79  PVPFPCRSPDACKDNGLTCPIKAGVVANYKTTLPVLKSYPKVSVDVKWEL-KKDEEDLVC 137

Query: 412 VQMPTSI 432
           + +P  I
Sbjct: 138 ILIPARI 144
>sp|P27236|DCP_SALTY Peptidyl-dipeptidase dcp (Dipeptidyl carboxypeptidase)
          Length = 680

 Score = 29.3 bits (64), Expect = 5.6
 Identities = 13/28 (46%), Positives = 17/28 (60%)
 Frame = +1

Query: 313 TYTNSIDILKYYPSVRVTITWELIDADG 396
           T+    DI  Y+P VRV   WE+ D+DG
Sbjct: 380 TFVERFDIPVYHPDVRV---WEIFDSDG 404
>sp|Q25158|OPSC2_HEMSA Compound eye opsin BCRH2
          Length = 377

 Score = 28.9 bits (63), Expect = 7.3
 Identities = 11/31 (35%), Positives = 20/31 (64%), Gaps = 1/31 (3%)
 Frame = -1

Query: 185 FSLDLYLIVI-CGFVPFFNWHGWVLQGVIST 96
           F+L  ++I I C   PFF W  ++L+G++ +
Sbjct: 174 FALISWVIAIGCALPPFFGWGNYILEGILDS 204
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,044,441
Number of Sequences: 369166
Number of extensions: 905251
Number of successful extensions: 1856
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1803
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1848
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3255600150
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00790

  1. Dr_sW_020_G05
  2. Dr_sW_017_H14
  3. Dr_sW_010_N10