Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00769 (773 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P13051|UNG_HUMAN Uracil-DNA glycosylase (UDG) 259 6e-69 sp|P97931|UNG_MOUSE Uracil-DNA glycosylase (UDG) 251 2e-66 sp|Q7VMC0|UNG_HAEDU Uracil-DNA glycosylase (UDG) 238 1e-62 sp|Q64PM3|UNG2_BACFR Uracil-DNA glycosylase 2 (UDG 2) >gi|7... 231 2e-60 sp|Q65DN9|UNG_BACLD Uracil-DNA glycosylase (UDG) 229 8e-60 sp|Q8A5V6|UNG_BACTN Uracil-DNA glycosylase (UDG) 229 8e-60 sp|P53766|UNG_DICDI Uracil-DNA glycosylase (UDG) 228 1e-59 sp|Q8ZD85|UNG_YERPE Uracil-DNA glycosylase (UDG) 226 7e-59 sp|Q9KPK8|UNG_VIBCH Uracil-DNA glycosylase (UDG) 224 2e-58 sp|Q836Z5|UNG_ENTFA Uracil-DNA glycosylase (UDG) 224 2e-58
>sp|P13051|UNG_HUMAN Uracil-DNA glycosylase (UDG) Length = 313 Score = 259 bits (662), Expect = 6e-69 Identities = 125/217 (57%), Positives = 153/217 (70%), Gaps = 1/217 (0%) Frame = +2 Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPY 208 SW + L E YF KLM F+ E K ++PP QVF+WT + ++K+VKVVILGQDPY Sbjct: 97 SWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPY 156 Query: 209 HGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSVL 388 HG QAHGL FSV P PP SL NIY EL TDIE F P HG+LS WA QGVL+LN+VL Sbjct: 157 HGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVL 216 Query: 389 TVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVIQCA 565 TV+A NSHKE+GWE TDAV+ LN+ N LVF+LWG YAQKK ++++RK+H V+Q A Sbjct: 217 TVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTA 276 Query: 566 HPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWKDL 676 HPSPLS + GFFG + FS+ N L+ IDWK+L Sbjct: 277 HPSPLSVYRGFFGCRHFSKTNELLQKSGKKPIDWKEL 313
>sp|P97931|UNG_MOUSE Uracil-DNA glycosylase (UDG) Length = 306 Score = 251 bits (640), Expect = 2e-66 Identities = 120/217 (55%), Positives = 153/217 (70%), Gaps = 1/217 (0%) Frame = +2 Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPY 208 SW + L E YF KLM F+ E + ++PP +QVF+WT + ++++VKVVILGQDPY Sbjct: 90 SWKQQLCGEFGKPYFVKLMGFVAEERNHHKVYPPPEQVFTWTQMCDIRDVKVVILGQDPY 149 Query: 209 HGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSVL 388 HG QAHGL FSV P PP SL NI+ EL TDI+GF P HG+LS WA QGVL+LN+VL Sbjct: 150 HGPNQAHGLCFSVQRPVPPPPSLENIFKELSTDIDGFVHPGHGDLSGWARQGVLLLNAVL 209 Query: 389 TVKAGTPNSHKEKGWENLTDAVIRHLNKK-ENLVFILWGKYAQKKCASLNRKKHLVIQCA 565 TV+A NSHKE+GWE TDAV+ LN+ LVF+LWG YAQKK + ++RK+H V+Q A Sbjct: 210 TVRAHQANSHKERGWEQFTDAVVSWLNQNLSGLVFLLWGSYAQKKGSVIDRKRHHVLQTA 269 Query: 566 HPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWKDL 676 HPSPLS + GF G + FS+AN L+ I+WK+L Sbjct: 270 HPSPLSVYRGFLGCRHFSKANELLQKSGKKPINWKEL 306
>sp|Q7VMC0|UNG_HAEDU Uracil-DNA glycosylase (UDG) Length = 223 Score = 238 bits (607), Expect = 1e-62 Identities = 122/216 (56%), Positives = 150/216 (69%), Gaps = 2/216 (0%) Frame = +2 Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 205 SW E + E YF++L+ + S +I+PP+ +VFS LT+ K VKVVILGQDP Sbjct: 3 SWTEAIGEEKVQPYFQQLLQQVYQARASGKIIYPPQHEVFSAFALTDFKAVKVVILGQDP 62 Query: 206 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 385 YHG QAHGLAFSV PP SLVNIY EL DI GF++P HG L +WA QGVL+LN+V Sbjct: 63 YHGPNQAHGLAFSVKPSVVPPPSLVNIYKELAQDIAGFQVPSHGYLIDWAKQGVLLLNTV 122 Query: 386 LTVKAGTPNSHKEKGWENLTDAVIRHLN-KKENLVFILWGKYAQKKCASLNRKKHLVIQC 562 LTV+ G +SH GWE TD VI LN +ENLVF+LWG +AQKK +NR +H V+ Sbjct: 123 LTVQQGMAHSHATLGWEIFTDKVIAQLNDHRENLVFLLWGSHAQKKGQFINRSRHCVLTA 182 Query: 563 AHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670 HPSPLSAH GFFG + FS+ANAYL+SK IA I+W+ Sbjct: 183 PHPSPLSAHRGFFGCQHFSKANAYLQSKGIATINWQ 218
>sp|Q64PM3|UNG2_BACFR Uracil-DNA glycosylase 2 (UDG 2) sp|Q5L9D9|UNG2_BACFN Uracil-DNA glycosylase 2 (UDG 2) Length = 220 Score = 231 bits (589), Expect = 2e-60 Identities = 119/217 (54%), Positives = 147/217 (67%), Gaps = 1/217 (0%) Frame = +2 Query: 20 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 199 I SW L+PE YF+ L F+ +E+ IFPP K +F+ +L VKVVI+GQ Sbjct: 5 IEESWKTHLEPEFEKDYFRTLTEFVRSEYSQYQIFPPGKLIFNAFNLCPFDKVKVVIIGQ 64 Query: 200 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 379 DPYHG GQAHGL FSV + P SLVNI+ E+K DI G P GNL+ WA QGVL+LN Sbjct: 65 DPYHGPGQAHGLCFSVNDGVAFPPSLVNIFKEIKEDI-GTPAPSTGNLTRWAEQGVLLLN 123 Query: 380 SVLTVKAGTPNSHKEKGWENLTDAVIRHL-NKKENLVFILWGKYAQKKCASLNRKKHLVI 556 + LTV+A SH+ +GWE TDA IR L ++ENLVFILWG YAQKK A ++R KHLV+ Sbjct: 124 ATLTVRAHQAGSHQRRGWEEFTDAAIRVLAEERENLVFILWGSYAQKKGAFIDRNKHLVL 183 Query: 557 QCAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDW 667 AHPSPLSA+ GFFG+K FS+ N YLK+ EI+W Sbjct: 184 SSAHPSPLSAYNGFFGNKHFSKTNEYLKAHGKTEINW 220
>sp|Q65DN9|UNG_BACLD Uracil-DNA glycosylase (UDG) Length = 225 Score = 229 bits (583), Expect = 8e-60 Identities = 113/217 (52%), Positives = 149/217 (68%), Gaps = 1/217 (0%) Frame = +2 Query: 20 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 199 ++ SW + LK E + Y+++L L E+ + ++P +++ H T +NVKVVILGQ Sbjct: 5 LNDSWWQQLKDEFDKPYYQELREMLKREYAEHTVYPEPNDIYNALHYTSYENVKVVILGQ 64 Query: 200 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 379 DPYHG GQAHGL+FSV PP SL NI+ EL+ DI G IP+HG+L +WA QGVL+LN Sbjct: 65 DPYHGPGQAHGLSFSVQPGVNPPPSLKNIFIELQNDI-GADIPNHGSLVSWAKQGVLLLN 123 Query: 380 SVLTVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVI 556 +VLTV+ G NSHK KGWE LTD++I LNK++ +VFILWG++AQ K ++ KH +I Sbjct: 124 TVLTVRRGQANSHKGKGWEQLTDSIIDVLNKRDKPVVFILWGRHAQMKKERIDTSKHFII 183 Query: 557 QCAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDW 667 Q HPSP SA GFFGS+ FSRAN YL+ IDW Sbjct: 184 QSPHPSPFSARNGFFGSRPFSRANQYLEQIGDEPIDW 220
>sp|Q8A5V6|UNG_BACTN Uracil-DNA glycosylase (UDG) Length = 220 Score = 229 bits (583), Expect = 8e-60 Identities = 119/217 (54%), Positives = 147/217 (67%), Gaps = 1/217 (0%) Frame = +2 Query: 20 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 199 I SW L+PE YF+ L F+ +E+ IFPP K +F+ +L VKVVI+GQ Sbjct: 5 IEESWKTHLQPEFEKDYFRTLTEFVKSEYSQYQIFPPGKLIFNAFNLCPFDKVKVVIIGQ 64 Query: 200 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 379 DPYHG GQAHGL FSV + P SLVNI+ E+K DI G P GNL+ WA QGVL+LN Sbjct: 65 DPYHGPGQAHGLCFSVNDGVPFPPSLVNIFKEIKADI-GTDAPTTGNLTRWAEQGVLLLN 123 Query: 380 SVLTVKAGTPNSHKEKGWENLTDAVIRHL-NKKENLVFILWGKYAQKKCASLNRKKHLVI 556 + LTV+A SH+ +GWE TDA IR L ++E+LVFILWG YAQ+K A ++R KHLV+ Sbjct: 124 ATLTVRAHQAGSHQNRGWEAFTDAAIRALAEEREHLVFILWGAYAQRKGAFIDRNKHLVL 183 Query: 557 QCAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDW 667 AHPSPLSA+ GFFG+K FSRAN YLK+ EI W Sbjct: 184 SSAHPSPLSAYNGFFGNKHFSRANDYLKANGETEIIW 220
>sp|P53766|UNG_DICDI Uracil-DNA glycosylase (UDG) Length = 257 Score = 228 bits (581), Expect = 1e-59 Identities = 118/217 (54%), Positives = 151/217 (69%), Gaps = 4/217 (1%) Frame = +2 Query: 32 WLEILKPEINSTYFKKLMAFLVNEH--KSNVIFPPEKQVFSWTHLTELKNVKVVILGQDP 205 W E L E YFKK++ L + K I+PP+ ++FS + L++VKVVI+GQDP Sbjct: 39 WKEALSGEFGKAYFKKMITQLNKRYSSKEKPIYPPKNEIFSAFNYAHLEDVKVVIIGQDP 98 Query: 206 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIP-DHGNLSNWATQGVLMLNS 382 YHGKGQAHGL+FSV + PP SL+NIY EL+TDIEGFK P +G L WA QGV +LN+ Sbjct: 99 YHGKGQAHGLSFSVKKGVSPPPSLINIYKELETDIEGFKRPLKNGFLEPWARQGVFLLNA 158 Query: 383 VLTVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVIQ 559 VLTV+ TPNSHK+ GW + TDAV++ L+K++ +VFILWG +AQKK K HLV++ Sbjct: 159 VLTVEEATPNSHKDFGWADFTDAVLKILSKQDQPIVFILWGGFAQKKEKLFTNKNHLVLK 218 Query: 560 CAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670 HPSPLS F G K FS++N +LKSK I EIDWK Sbjct: 219 SGHPSPLSI-KHFIGCKHFSKSNEFLKSKGIEEIDWK 254
>sp|Q8ZD85|UNG_YERPE Uracil-DNA glycosylase (UDG) Length = 228 Score = 226 bits (575), Expect = 7e-59 Identities = 111/216 (51%), Positives = 148/216 (68%), Gaps = 2/216 (0%) Frame = +2 Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 205 +W +++ E YFK +A++ E ++ I+PP+K +F+ LTEL VKVVILGQDP Sbjct: 6 TWHDVIGQEKEQPYFKDTLAYVAAERRAGKTIYPPQKDIFNAFRLTELDQVKVVILGQDP 65 Query: 206 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 385 YHG QAHGL+FSVL P SL NIY EL TDI GF+ P+HG L +WA QGVL+LN+V Sbjct: 66 YHGPNQAHGLSFSVLPGVPAPPSLGNIYKELVTDIPGFQRPNHGFLQSWAEQGVLLLNTV 125 Query: 386 LTVKAGTPNSHKEKGWENLTDAVIRHLNK-KENLVFILWGKYAQKKCASLNRKKHLVIQC 562 LTV+AG +SH GWE TD VI LN+ +E ++F+LWG +AQKK +N ++H +++ Sbjct: 126 LTVEAGKAHSHANLGWETFTDKVIAALNEHREGVIFMLWGSHAQKKGRIINTERHYILKA 185 Query: 563 AHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670 HPSPLSAH GF G K FS+AN L+ + IDW+ Sbjct: 186 PHPSPLSAHRGFLGCKHFSQANQLLQQQNQQPIDWQ 221
>sp|Q9KPK8|UNG_VIBCH Uracil-DNA glycosylase (UDG) Length = 226 Score = 224 bits (572), Expect = 2e-58 Identities = 111/216 (51%), Positives = 148/216 (68%), Gaps = 2/216 (0%) Frame = +2 Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 205 +W +++ E YF++ + F+ ++ ++ VI+PP K VF+ TE +VKVVILGQDP Sbjct: 6 TWHDVIGNEKQQAYFQQTLQFVESQRQAGKVIYPPAKDVFNAFRFTEFGDVKVVILGQDP 65 Query: 206 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 385 YHG QAHGL FSVL K P SLVNIY EL DI GF+IP HG L +WA QGVL+LN+V Sbjct: 66 YHGPNQAHGLCFSVLPGVKTPPSLVNIYKELAQDIPGFQIPPHGYLQSWAQQGVLLLNTV 125 Query: 386 LTVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVIQC 562 LTV+ G +SH GWE TD VI LN+ N L+F+LWG +AQKK ++R++H V+ Sbjct: 126 LTVEQGMAHSHANTGWETFTDRVIDALNQHRNGLIFLLWGSHAQKKGQMIDRQRHHVLMA 185 Query: 563 AHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670 HPSPLSAH GF G + FS+ N L+++ IA I+W+ Sbjct: 186 PHPSPLSAHRGFLGCRHFSKTNQLLQAQGIAPINWQ 221
>sp|Q836Z5|UNG_ENTFA Uracil-DNA glycosylase (UDG) Length = 226 Score = 224 bits (571), Expect = 2e-58 Identities = 113/218 (51%), Positives = 149/218 (68%), Gaps = 1/218 (0%) Frame = +2 Query: 20 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 199 IH SW IL E Y+++L FL E+++ I+P +FS LT + VKVVILGQ Sbjct: 5 IHNSWQNILSAEFEKPYYQELREFLKKEYQTQTIYPDMYHLFSALELTPFEEVKVVILGQ 64 Query: 200 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 379 DPYHG QAHGL+FSV K P SL NIY EL+ D+ G++ +HG L +WA QGVL+LN Sbjct: 65 DPYHGPNQAHGLSFSVQPGVKVPPSLANIYKELQADL-GYQPVNHGFLESWAKQGVLLLN 123 Query: 380 SVLTVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVI 556 +VLTV+AG SH+ KGWE LTD +I LN++E +VFILWG+ AQ+K ++ +H++I Sbjct: 124 TVLTVRAGQAYSHRGKGWEQLTDVIIEKLNEREKPVVFILWGRPAQEKIKMIDTTRHVII 183 Query: 557 QCAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670 + HPSPLSAH GFFGS+ FS+ANA L+ IDW+ Sbjct: 184 KSPHPSPLSAHRGFFGSRPFSQANAALERLGETPIDWQ 221
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 85,257,196 Number of Sequences: 369166 Number of extensions: 1736230 Number of successful extensions: 4433 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4063 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4152 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7212136400 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)