Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_B04
(453 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P13051|UNG_HUMAN Uracil-DNA glycosylase (UDG) 184 6e-47
sp|P97931|UNG_MOUSE Uracil-DNA glycosylase (UDG) 182 3e-46
sp|Q9RWH9|UNG_DEIRA Uracil-DNA glycosylase (UDG) 163 2e-40
sp|P53766|UNG_DICDI Uracil-DNA glycosylase (UDG) 162 3e-40
sp|Q65DN9|UNG_BACLD Uracil-DNA glycosylase (UDG) 161 7e-40
sp|Q8ZD85|UNG_YERPE Uracil-DNA glycosylase (UDG) 160 2e-39
sp|Q87SC4|UNG_VIBPA Uracil-DNA glycosylase (UDG) 159 2e-39
sp|Q9KPK8|UNG_VIBCH Uracil-DNA glycosylase (UDG) 158 6e-39
sp|Q8DEP7|UNG_VIBVU Uracil-DNA glycosylase (UDG) >gi|454772... 157 1e-38
sp|Q836Z5|UNG_ENTFA Uracil-DNA glycosylase (UDG) 157 1e-38
>sp|P13051|UNG_HUMAN Uracil-DNA glycosylase (UDG)
Length = 313
Score = 184 bits (468), Expect = 6e-47
Identities = 88/147 (59%), Positives = 103/147 (70%)
Frame = +1
Query: 13 SWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPY 192
SW + L E YF KLM F+ E K ++PP QVF+WT + ++K+VKVVILGQDPY
Sbjct: 97 SWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPY 156
Query: 193 HGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSVL 372
HG QAHGL FSV P PP SL NIY EL TDIE F P HG+LS WA QGVL+LN+VL
Sbjct: 157 HGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVL 216
Query: 373 TVKAGTPNSHKEKGWENLTDAVIRHLN 453
TV+A NSHKE+GWE TDAV+ LN
Sbjct: 217 TVRAHQANSHKERGWEQFTDAVVSWLN 243
>sp|P97931|UNG_MOUSE Uracil-DNA glycosylase (UDG)
Length = 306
Score = 182 bits (462), Expect = 3e-46
Identities = 85/147 (57%), Positives = 105/147 (71%)
Frame = +1
Query: 13 SWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPY 192
SW + L E YF KLM F+ E + ++PP +QVF+WT + ++++VKVVILGQDPY
Sbjct: 90 SWKQQLCGEFGKPYFVKLMGFVAEERNHHKVYPPPEQVFTWTQMCDIRDVKVVILGQDPY 149
Query: 193 HGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSVL 372
HG QAHGL FSV P PP SL NI+ EL TDI+GF P HG+LS WA QGVL+LN+VL
Sbjct: 150 HGPNQAHGLCFSVQRPVPPPPSLENIFKELSTDIDGFVHPGHGDLSGWARQGVLLLNAVL 209
Query: 373 TVKAGTPNSHKEKGWENLTDAVIRHLN 453
TV+A NSHKE+GWE TDAV+ LN
Sbjct: 210 TVRAHQANSHKERGWEQFTDAVVSWLN 236
>sp|Q9RWH9|UNG_DEIRA Uracil-DNA glycosylase (UDG)
Length = 247
Score = 163 bits (412), Expect = 2e-40
Identities = 82/146 (56%), Positives = 98/146 (67%)
Frame = +1
Query: 16 WLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPYH 195
W E L PE ++ YF +L FL E K I+PP VF+ T L VKV+ILGQDPYH
Sbjct: 27 WQEALLPEFSAPYFHELTDFLRQERKEYTIYPPAPDVFNALRYTPLGEVKVLILGQDPYH 86
Query: 196 GKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSVLT 375
G QAHGL+FSV + P SL NIY EL DI GF P HG L +WA QGVL+LN+VLT
Sbjct: 87 GPNQAHGLSFSVRPGVRVPPSLRNIYKELTEDIPGFVAPKHGYLRSWAEQGVLLLNAVLT 146
Query: 376 VKAGTPNSHKEKGWENLTDAVIRHLN 453
V+AG NSH+ KGWE+ TDAVI+ +N
Sbjct: 147 VRAGQANSHQGKGWEHFTDAVIKAVN 172
>sp|P53766|UNG_DICDI Uracil-DNA glycosylase (UDG)
Length = 257
Score = 162 bits (410), Expect = 3e-40
Identities = 81/149 (54%), Positives = 105/149 (70%), Gaps = 3/149 (2%)
Frame = +1
Query: 16 WLEILKPEINSTYFKKLMAFLVNEH--KSNVIFPPEKQVFSWTHLTELKNVKVVILGQDP 189
W E L E YFKK++ L + K I+PP+ ++FS + L++VKVVI+GQDP
Sbjct: 39 WKEALSGEFGKAYFKKMITQLNKRYSSKEKPIYPPKNEIFSAFNYAHLEDVKVVIIGQDP 98
Query: 190 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIP-DHGNLSNWATQGVLMLNS 366
YHGKGQAHGL+FSV + PP SL+NIY EL+TDIEGFK P +G L WA QGV +LN+
Sbjct: 99 YHGKGQAHGLSFSVKKGVSPPPSLINIYKELETDIEGFKRPLKNGFLEPWARQGVFLLNA 158
Query: 367 VLTVKAGTPNSHKEKGWENLTDAVIRHLN 453
VLTV+ TPNSHK+ GW + TDAV++ L+
Sbjct: 159 VLTVEEATPNSHKDFGWADFTDAVLKILS 187
>sp|Q65DN9|UNG_BACLD Uracil-DNA glycosylase (UDG)
Length = 225
Score = 161 bits (407), Expect = 7e-40
Identities = 78/150 (52%), Positives = 104/150 (69%)
Frame = +1
Query: 4 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 183
++ SW + LK E + Y+++L L E+ + ++P +++ H T +NVKVVILGQ
Sbjct: 5 LNDSWWQQLKDEFDKPYYQELREMLKREYAEHTVYPEPNDIYNALHYTSYENVKVVILGQ 64
Query: 184 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 363
DPYHG GQAHGL+FSV PP SL NI+ EL+ DI G IP+HG+L +WA QGVL+LN
Sbjct: 65 DPYHGPGQAHGLSFSVQPGVNPPPSLKNIFIELQNDI-GADIPNHGSLVSWAKQGVLLLN 123
Query: 364 SVLTVKAGTPNSHKEKGWENLTDAVIRHLN 453
+VLTV+ G NSHK KGWE LTD++I LN
Sbjct: 124 TVLTVRRGQANSHKGKGWEQLTDSIIDVLN 153
>sp|Q8ZD85|UNG_YERPE Uracil-DNA glycosylase (UDG)
Length = 228
Score = 160 bits (404), Expect = 2e-39
Identities = 80/148 (54%), Positives = 101/148 (68%), Gaps = 1/148 (0%)
Frame = +1
Query: 13 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 189
+W +++ E YFK +A++ E ++ I+PP+K +F+ LTEL VKVVILGQDP
Sbjct: 6 TWHDVIGQEKEQPYFKDTLAYVAAERRAGKTIYPPQKDIFNAFRLTELDQVKVVILGQDP 65
Query: 190 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 369
YHG QAHGL+FSVL P SL NIY EL TDI GF+ P+HG L +WA QGVL+LN+V
Sbjct: 66 YHGPNQAHGLSFSVLPGVPAPPSLGNIYKELVTDIPGFQRPNHGFLQSWAEQGVLLLNTV 125
Query: 370 LTVKAGTPNSHKEKGWENLTDAVIRHLN 453
LTV+AG +SH GWE TD VI LN
Sbjct: 126 LTVEAGKAHSHANLGWETFTDKVIAALN 153
>sp|Q87SC4|UNG_VIBPA Uracil-DNA glycosylase (UDG)
Length = 226
Score = 159 bits (403), Expect = 2e-39
Identities = 79/149 (53%), Positives = 99/149 (66%), Gaps = 1/149 (0%)
Frame = +1
Query: 10 PSWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQD 186
P+W +++ E +YF + F+ E + I+PP K VF+ TE +VKVVILGQD
Sbjct: 5 PTWHDVIGEEKKQSYFVDTLNFVEAERAAGKAIYPPAKDVFNAFRFTEFNDVKVVILGQD 64
Query: 187 PYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNS 366
PYHG QAHGL FSVL K P SLVN+Y EL DIEGF+IP HG L +WA QGVL+LN+
Sbjct: 65 PYHGPNQAHGLCFSVLPGIKTPPSLVNMYKELAQDIEGFQIPQHGFLQSWAEQGVLLLNT 124
Query: 367 VLTVKAGTPNSHKEKGWENLTDAVIRHLN 453
VLTV+ G +SH + GWE TD VI +N
Sbjct: 125 VLTVEQGKAHSHSKTGWETFTDRVIEAIN 153
>sp|Q9KPK8|UNG_VIBCH Uracil-DNA glycosylase (UDG)
Length = 226
Score = 158 bits (399), Expect = 6e-39
Identities = 79/148 (53%), Positives = 100/148 (67%), Gaps = 1/148 (0%)
Frame = +1
Query: 13 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 189
+W +++ E YF++ + F+ ++ ++ VI+PP K VF+ TE +VKVVILGQDP
Sbjct: 6 TWHDVIGNEKQQAYFQQTLQFVESQRQAGKVIYPPAKDVFNAFRFTEFGDVKVVILGQDP 65
Query: 190 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 369
YHG QAHGL FSVL K P SLVNIY EL DI GF+IP HG L +WA QGVL+LN+V
Sbjct: 66 YHGPNQAHGLCFSVLPGVKTPPSLVNIYKELAQDIPGFQIPPHGYLQSWAQQGVLLLNTV 125
Query: 370 LTVKAGTPNSHKEKGWENLTDAVIRHLN 453
LTV+ G +SH GWE TD VI LN
Sbjct: 126 LTVEQGMAHSHANTGWETFTDRVIDALN 153
>sp|Q8DEP7|UNG_VIBVU Uracil-DNA glycosylase (UDG)
sp|Q7MNR0|UNG_VIBVY Uracil-DNA glycosylase (UDG)
Length = 226
Score = 157 bits (397), Expect = 1e-38
Identities = 78/148 (52%), Positives = 101/148 (68%), Gaps = 1/148 (0%)
Frame = +1
Query: 13 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 189
+W +++ E +YF++ + F+ E ++ VI+PP K VF+ TE ++VKVVILGQDP
Sbjct: 6 TWHDVIGAEKEQSYFQQTLNFVEAERQAGKVIYPPAKDVFNAFRYTEFQDVKVVILGQDP 65
Query: 190 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 369
YHG QAHGL FSVL K P SLVN+Y EL DI+GF+IP HG L WA QGVL+LN+V
Sbjct: 66 YHGPNQAHGLCFSVLPGIKTPPSLVNMYKELAQDIQGFQIPAHGYLEAWAKQGVLLLNTV 125
Query: 370 LTVKAGTPNSHKEKGWENLTDAVIRHLN 453
LTV+ G +SH GWE TD VI +N
Sbjct: 126 LTVEQGKAHSHASLGWETFTDKVIEAIN 153
>sp|Q836Z5|UNG_ENTFA Uracil-DNA glycosylase (UDG)
Length = 226
Score = 157 bits (397), Expect = 1e-38
Identities = 79/150 (52%), Positives = 100/150 (66%)
Frame = +1
Query: 4 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 183
IH SW IL E Y+++L FL E+++ I+P +FS LT + VKVVILGQ
Sbjct: 5 IHNSWQNILSAEFEKPYYQELREFLKKEYQTQTIYPDMYHLFSALELTPFEEVKVVILGQ 64
Query: 184 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 363
DPYHG QAHGL+FSV K P SL NIY EL+ D+ G++ +HG L +WA QGVL+LN
Sbjct: 65 DPYHGPNQAHGLSFSVQPGVKVPPSLANIYKELQADL-GYQPVNHGFLESWAKQGVLLLN 123
Query: 364 SVLTVKAGTPNSHKEKGWENLTDAVIRHLN 453
+VLTV+AG SH+ KGWE LTD +I LN
Sbjct: 124 TVLTVRAGQAYSHRGKGWEQLTDVIIEKLN 153
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.316 0.135 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,960,279
Number of Sequences: 369166
Number of extensions: 967386
Number of successful extensions: 2569
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2406
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2454
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2435140505
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)