Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_L14
(444 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P13051|UNG_HUMAN Uracil-DNA glycosylase (UDG) 122 3e-28
sp|P97931|UNG_MOUSE Uracil-DNA glycosylase (UDG) 120 1e-27
sp|P53766|UNG_DICDI Uracil-DNA glycosylase (UDG) 113 2e-25
sp|O74834|UNG_SCHPO Uracil-DNA glycosylase (UDG) 109 3e-24
sp|P12887|UNG_YEAST Uracil-DNA glycosylase, mitochondrial p... 108 7e-24
sp|Q87SC4|UNG_VIBPA Uracil-DNA glycosylase (UDG) 108 7e-24
sp|Q8DEP7|UNG_VIBVU Uracil-DNA glycosylase (UDG) >gi|454772... 107 9e-24
sp|Q8ZD85|UNG_YERPE Uracil-DNA glycosylase (UDG) 107 1e-23
sp|Q9KPK8|UNG_VIBCH Uracil-DNA glycosylase (UDG) 107 2e-23
sp|Q7VMC0|UNG_HAEDU Uracil-DNA glycosylase (UDG) 106 2e-23
>sp|P13051|UNG_HUMAN Uracil-DNA glycosylase (UDG)
Length = 313
Score = 122 bits (307), Expect = 3e-28
Identities = 58/102 (56%), Positives = 67/102 (65%)
Frame = +1
Query: 25 SWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPY 204
SW + L E YF KLM F+ E K ++PP QVF+WT + ++K+VKVVILGQDPY
Sbjct: 97 SWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPY 156
Query: 205 HGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDH 330
HG QAHGL FSV P PP SL NIY EL TDIE F P H
Sbjct: 157 HGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGH 198
>sp|P97931|UNG_MOUSE Uracil-DNA glycosylase (UDG)
Length = 306
Score = 120 bits (301), Expect = 1e-27
Identities = 55/102 (53%), Positives = 69/102 (67%)
Frame = +1
Query: 25 SWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPY 204
SW + L E YF KLM F+ E + ++PP +QVF+WT + ++++VKVVILGQDPY
Sbjct: 90 SWKQQLCGEFGKPYFVKLMGFVAEERNHHKVYPPPEQVFTWTQMCDIRDVKVVILGQDPY 149
Query: 205 HGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDH 330
HG QAHGL FSV P PP SL NI+ EL TDI+GF P H
Sbjct: 150 HGPNQAHGLCFSVQRPVPPPPSLENIFKELSTDIDGFVHPGH 191
>sp|P53766|UNG_DICDI Uracil-DNA glycosylase (UDG)
Length = 257
Score = 113 bits (282), Expect = 2e-25
Identities = 55/101 (54%), Positives = 70/101 (69%), Gaps = 2/101 (1%)
Frame = +1
Query: 28 WLEILKPEINSTYFKKLMAFLVNEH--KSNVIFPPEKQVFSWTHLTELKNVKVVILGQDP 201
W E L E YFKK++ L + K I+PP+ ++FS + L++VKVVI+GQDP
Sbjct: 39 WKEALSGEFGKAYFKKMITQLNKRYSSKEKPIYPPKNEIFSAFNYAHLEDVKVVIIGQDP 98
Query: 202 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIP 324
YHGKGQAHGL+FSV + PP SL+NIY EL+TDIEGFK P
Sbjct: 99 YHGKGQAHGLSFSVKKGVSPPPSLINIYKELETDIEGFKRP 139
>sp|O74834|UNG_SCHPO Uracil-DNA glycosylase (UDG)
Length = 322
Score = 109 bits (272), Expect = 3e-24
Identities = 52/106 (49%), Positives = 66/106 (62%)
Frame = +1
Query: 7 INTIHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVI 186
I+T+ SW + LK E YF L FL+ E +S +FPP++ ++SW+H T L KV++
Sbjct: 79 IDTLESSWFDALKDEFLKPYFLNLKEFLMKEWQSQRVFPPKEDIYSWSHHTPLHKTKVIL 138
Query: 187 LGQDPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIP 324
LGQDPYH GQAHGL FSV P SLVNIY +K D F IP
Sbjct: 139 LGQDPYHNIGQAHGLCFSVRPGIPCPPSLVNIYKAIKIDYPDFVIP 184
>sp|P12887|UNG_YEAST Uracil-DNA glycosylase, mitochondrial precursor (UDG)
Length = 359
Score = 108 bits (269), Expect = 7e-24
Identities = 53/110 (48%), Positives = 65/110 (59%)
Frame = +1
Query: 7 INTIHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVI 186
+ TI SW L E YF KL F+ E + +FPP K ++SWT LT VKVVI
Sbjct: 99 LETIDDSWFPHLMDEFKKPYFVKLKQFVTKEQADHTVFPPAKDIYSWTRLTPFNKVKVVI 158
Query: 187 LGQDPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHEI 336
+GQDPYH QAHGLAFSV P P SL NIY ELK + F + D+++
Sbjct: 159 IGQDPYHNFNQAHGLAFSVKPPTPAPPSLKNIYKELKQEYPDF-VEDNKV 207
>sp|Q87SC4|UNG_VIBPA Uracil-DNA glycosylase (UDG)
Length = 226
Score = 108 bits (269), Expect = 7e-24
Identities = 54/104 (51%), Positives = 67/104 (64%), Gaps = 1/104 (0%)
Frame = +1
Query: 22 PSWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQD 198
P+W +++ E +YF + F+ E + I+PP K VF+ TE +VKVVILGQD
Sbjct: 5 PTWHDVIGEEKKQSYFVDTLNFVEAERAAGKAIYPPAKDVFNAFRFTEFNDVKVVILGQD 64
Query: 199 PYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDH 330
PYHG QAHGL FSVL K P SLVN+Y EL DIEGF+IP H
Sbjct: 65 PYHGPNQAHGLCFSVLPGIKTPPSLVNMYKELAQDIEGFQIPQH 108
>sp|Q8DEP7|UNG_VIBVU Uracil-DNA glycosylase (UDG)
sp|Q7MNR0|UNG_VIBVY Uracil-DNA glycosylase (UDG)
Length = 226
Score = 107 bits (268), Expect = 9e-24
Identities = 53/103 (51%), Positives = 71/103 (68%), Gaps = 1/103 (0%)
Frame = +1
Query: 25 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 201
+W +++ E +YF++ + F+ E ++ VI+PP K VF+ TE ++VKVVILGQDP
Sbjct: 6 TWHDVIGAEKEQSYFQQTLNFVEAERQAGKVIYPPAKDVFNAFRYTEFQDVKVVILGQDP 65
Query: 202 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDH 330
YHG QAHGL FSVL K P SLVN+Y EL DI+GF+IP H
Sbjct: 66 YHGPNQAHGLCFSVLPGIKTPPSLVNMYKELAQDIQGFQIPAH 108
>sp|Q8ZD85|UNG_YERPE Uracil-DNA glycosylase (UDG)
Length = 228
Score = 107 bits (267), Expect = 1e-23
Identities = 53/103 (51%), Positives = 69/103 (66%), Gaps = 1/103 (0%)
Frame = +1
Query: 25 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 201
+W +++ E YFK +A++ E ++ I+PP+K +F+ LTEL VKVVILGQDP
Sbjct: 6 TWHDVIGQEKEQPYFKDTLAYVAAERRAGKTIYPPQKDIFNAFRLTELDQVKVVILGQDP 65
Query: 202 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDH 330
YHG QAHGL+FSVL P SL NIY EL TDI GF+ P+H
Sbjct: 66 YHGPNQAHGLSFSVLPGVPAPPSLGNIYKELVTDIPGFQRPNH 108
>sp|Q9KPK8|UNG_VIBCH Uracil-DNA glycosylase (UDG)
Length = 226
Score = 107 bits (266), Expect = 2e-23
Identities = 53/103 (51%), Positives = 69/103 (66%), Gaps = 1/103 (0%)
Frame = +1
Query: 25 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 201
+W +++ E YF++ + F+ ++ ++ VI+PP K VF+ TE +VKVVILGQDP
Sbjct: 6 TWHDVIGNEKQQAYFQQTLQFVESQRQAGKVIYPPAKDVFNAFRFTEFGDVKVVILGQDP 65
Query: 202 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDH 330
YHG QAHGL FSVL K P SLVNIY EL DI GF+IP H
Sbjct: 66 YHGPNQAHGLCFSVLPGVKTPPSLVNIYKELAQDIPGFQIPPH 108
>sp|Q7VMC0|UNG_HAEDU Uracil-DNA glycosylase (UDG)
Length = 223
Score = 106 bits (265), Expect = 2e-23
Identities = 55/103 (53%), Positives = 67/103 (65%), Gaps = 1/103 (0%)
Frame = +1
Query: 25 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 201
SW E + E YF++L+ + S +I+PP+ +VFS LT+ K VKVVILGQDP
Sbjct: 3 SWTEAIGEEKVQPYFQQLLQQVYQARASGKIIYPPQHEVFSAFALTDFKAVKVVILGQDP 62
Query: 202 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDH 330
YHG QAHGLAFSV PP SLVNIY EL DI GF++P H
Sbjct: 63 YHGPNQAHGLAFSVKPSVVPPPSLVNIYKELAQDIAGFQVPSH 105
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,001,133
Number of Sequences: 369166
Number of extensions: 923857
Number of successful extensions: 2429
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2326
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2400
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2344429560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)