Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_O18
(773 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P13051|UNG_HUMAN Uracil-DNA glycosylase (UDG) 259 6e-69
sp|P97931|UNG_MOUSE Uracil-DNA glycosylase (UDG) 251 2e-66
sp|Q7VMC0|UNG_HAEDU Uracil-DNA glycosylase (UDG) 238 1e-62
sp|Q64PM3|UNG2_BACFR Uracil-DNA glycosylase 2 (UDG 2) >gi|7... 231 2e-60
sp|Q65DN9|UNG_BACLD Uracil-DNA glycosylase (UDG) 229 8e-60
sp|Q8A5V6|UNG_BACTN Uracil-DNA glycosylase (UDG) 229 8e-60
sp|P53766|UNG_DICDI Uracil-DNA glycosylase (UDG) 228 1e-59
sp|Q8ZD85|UNG_YERPE Uracil-DNA glycosylase (UDG) 226 7e-59
sp|Q9KPK8|UNG_VIBCH Uracil-DNA glycosylase (UDG) 224 2e-58
sp|Q836Z5|UNG_ENTFA Uracil-DNA glycosylase (UDG) 224 2e-58
>sp|P13051|UNG_HUMAN Uracil-DNA glycosylase (UDG)
Length = 313
Score = 259 bits (662), Expect = 6e-69
Identities = 125/217 (57%), Positives = 153/217 (70%), Gaps = 1/217 (0%)
Frame = +2
Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPY 208
SW + L E YF KLM F+ E K ++PP QVF+WT + ++K+VKVVILGQDPY
Sbjct: 97 SWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPY 156
Query: 209 HGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSVL 388
HG QAHGL FSV P PP SL NIY EL TDIE F P HG+LS WA QGVL+LN+VL
Sbjct: 157 HGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVL 216
Query: 389 TVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVIQCA 565
TV+A NSHKE+GWE TDAV+ LN+ N LVF+LWG YAQKK ++++RK+H V+Q A
Sbjct: 217 TVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTA 276
Query: 566 HPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWKDL 676
HPSPLS + GFFG + FS+ N L+ IDWK+L
Sbjct: 277 HPSPLSVYRGFFGCRHFSKTNELLQKSGKKPIDWKEL 313
>sp|P97931|UNG_MOUSE Uracil-DNA glycosylase (UDG)
Length = 306
Score = 251 bits (640), Expect = 2e-66
Identities = 120/217 (55%), Positives = 153/217 (70%), Gaps = 1/217 (0%)
Frame = +2
Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQDPY 208
SW + L E YF KLM F+ E + ++PP +QVF+WT + ++++VKVVILGQDPY
Sbjct: 90 SWKQQLCGEFGKPYFVKLMGFVAEERNHHKVYPPPEQVFTWTQMCDIRDVKVVILGQDPY 149
Query: 209 HGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSVL 388
HG QAHGL FSV P PP SL NI+ EL TDI+GF P HG+LS WA QGVL+LN+VL
Sbjct: 150 HGPNQAHGLCFSVQRPVPPPPSLENIFKELSTDIDGFVHPGHGDLSGWARQGVLLLNAVL 209
Query: 389 TVKAGTPNSHKEKGWENLTDAVIRHLNKK-ENLVFILWGKYAQKKCASLNRKKHLVIQCA 565
TV+A NSHKE+GWE TDAV+ LN+ LVF+LWG YAQKK + ++RK+H V+Q A
Sbjct: 210 TVRAHQANSHKERGWEQFTDAVVSWLNQNLSGLVFLLWGSYAQKKGSVIDRKRHHVLQTA 269
Query: 566 HPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWKDL 676
HPSPLS + GF G + FS+AN L+ I+WK+L
Sbjct: 270 HPSPLSVYRGFLGCRHFSKANELLQKSGKKPINWKEL 306
>sp|Q7VMC0|UNG_HAEDU Uracil-DNA glycosylase (UDG)
Length = 223
Score = 238 bits (607), Expect = 1e-62
Identities = 122/216 (56%), Positives = 150/216 (69%), Gaps = 2/216 (0%)
Frame = +2
Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 205
SW E + E YF++L+ + S +I+PP+ +VFS LT+ K VKVVILGQDP
Sbjct: 3 SWTEAIGEEKVQPYFQQLLQQVYQARASGKIIYPPQHEVFSAFALTDFKAVKVVILGQDP 62
Query: 206 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 385
YHG QAHGLAFSV PP SLVNIY EL DI GF++P HG L +WA QGVL+LN+V
Sbjct: 63 YHGPNQAHGLAFSVKPSVVPPPSLVNIYKELAQDIAGFQVPSHGYLIDWAKQGVLLLNTV 122
Query: 386 LTVKAGTPNSHKEKGWENLTDAVIRHLN-KKENLVFILWGKYAQKKCASLNRKKHLVIQC 562
LTV+ G +SH GWE TD VI LN +ENLVF+LWG +AQKK +NR +H V+
Sbjct: 123 LTVQQGMAHSHATLGWEIFTDKVIAQLNDHRENLVFLLWGSHAQKKGQFINRSRHCVLTA 182
Query: 563 AHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670
HPSPLSAH GFFG + FS+ANAYL+SK IA I+W+
Sbjct: 183 PHPSPLSAHRGFFGCQHFSKANAYLQSKGIATINWQ 218
>sp|Q64PM3|UNG2_BACFR Uracil-DNA glycosylase 2 (UDG 2)
sp|Q5L9D9|UNG2_BACFN Uracil-DNA glycosylase 2 (UDG 2)
Length = 220
Score = 231 bits (589), Expect = 2e-60
Identities = 119/217 (54%), Positives = 147/217 (67%), Gaps = 1/217 (0%)
Frame = +2
Query: 20 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 199
I SW L+PE YF+ L F+ +E+ IFPP K +F+ +L VKVVI+GQ
Sbjct: 5 IEESWKTHLEPEFEKDYFRTLTEFVRSEYSQYQIFPPGKLIFNAFNLCPFDKVKVVIIGQ 64
Query: 200 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 379
DPYHG GQAHGL FSV + P SLVNI+ E+K DI G P GNL+ WA QGVL+LN
Sbjct: 65 DPYHGPGQAHGLCFSVNDGVAFPPSLVNIFKEIKEDI-GTPAPSTGNLTRWAEQGVLLLN 123
Query: 380 SVLTVKAGTPNSHKEKGWENLTDAVIRHL-NKKENLVFILWGKYAQKKCASLNRKKHLVI 556
+ LTV+A SH+ +GWE TDA IR L ++ENLVFILWG YAQKK A ++R KHLV+
Sbjct: 124 ATLTVRAHQAGSHQRRGWEEFTDAAIRVLAEERENLVFILWGSYAQKKGAFIDRNKHLVL 183
Query: 557 QCAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDW 667
AHPSPLSA+ GFFG+K FS+ N YLK+ EI+W
Sbjct: 184 SSAHPSPLSAYNGFFGNKHFSKTNEYLKAHGKTEINW 220
>sp|Q65DN9|UNG_BACLD Uracil-DNA glycosylase (UDG)
Length = 225
Score = 229 bits (583), Expect = 8e-60
Identities = 113/217 (52%), Positives = 149/217 (68%), Gaps = 1/217 (0%)
Frame = +2
Query: 20 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 199
++ SW + LK E + Y+++L L E+ + ++P +++ H T +NVKVVILGQ
Sbjct: 5 LNDSWWQQLKDEFDKPYYQELREMLKREYAEHTVYPEPNDIYNALHYTSYENVKVVILGQ 64
Query: 200 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 379
DPYHG GQAHGL+FSV PP SL NI+ EL+ DI G IP+HG+L +WA QGVL+LN
Sbjct: 65 DPYHGPGQAHGLSFSVQPGVNPPPSLKNIFIELQNDI-GADIPNHGSLVSWAKQGVLLLN 123
Query: 380 SVLTVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVI 556
+VLTV+ G NSHK KGWE LTD++I LNK++ +VFILWG++AQ K ++ KH +I
Sbjct: 124 TVLTVRRGQANSHKGKGWEQLTDSIIDVLNKRDKPVVFILWGRHAQMKKERIDTSKHFII 183
Query: 557 QCAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDW 667
Q HPSP SA GFFGS+ FSRAN YL+ IDW
Sbjct: 184 QSPHPSPFSARNGFFGSRPFSRANQYLEQIGDEPIDW 220
>sp|Q8A5V6|UNG_BACTN Uracil-DNA glycosylase (UDG)
Length = 220
Score = 229 bits (583), Expect = 8e-60
Identities = 119/217 (54%), Positives = 147/217 (67%), Gaps = 1/217 (0%)
Frame = +2
Query: 20 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 199
I SW L+PE YF+ L F+ +E+ IFPP K +F+ +L VKVVI+GQ
Sbjct: 5 IEESWKTHLQPEFEKDYFRTLTEFVKSEYSQYQIFPPGKLIFNAFNLCPFDKVKVVIIGQ 64
Query: 200 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 379
DPYHG GQAHGL FSV + P SLVNI+ E+K DI G P GNL+ WA QGVL+LN
Sbjct: 65 DPYHGPGQAHGLCFSVNDGVPFPPSLVNIFKEIKADI-GTDAPTTGNLTRWAEQGVLLLN 123
Query: 380 SVLTVKAGTPNSHKEKGWENLTDAVIRHL-NKKENLVFILWGKYAQKKCASLNRKKHLVI 556
+ LTV+A SH+ +GWE TDA IR L ++E+LVFILWG YAQ+K A ++R KHLV+
Sbjct: 124 ATLTVRAHQAGSHQNRGWEAFTDAAIRALAEEREHLVFILWGAYAQRKGAFIDRNKHLVL 183
Query: 557 QCAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDW 667
AHPSPLSA+ GFFG+K FSRAN YLK+ EI W
Sbjct: 184 SSAHPSPLSAYNGFFGNKHFSRANDYLKANGETEIIW 220
>sp|P53766|UNG_DICDI Uracil-DNA glycosylase (UDG)
Length = 257
Score = 228 bits (581), Expect = 1e-59
Identities = 118/217 (54%), Positives = 151/217 (69%), Gaps = 4/217 (1%)
Frame = +2
Query: 32 WLEILKPEINSTYFKKLMAFLVNEH--KSNVIFPPEKQVFSWTHLTELKNVKVVILGQDP 205
W E L E YFKK++ L + K I+PP+ ++FS + L++VKVVI+GQDP
Sbjct: 39 WKEALSGEFGKAYFKKMITQLNKRYSSKEKPIYPPKNEIFSAFNYAHLEDVKVVIIGQDP 98
Query: 206 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIP-DHGNLSNWATQGVLMLNS 382
YHGKGQAHGL+FSV + PP SL+NIY EL+TDIEGFK P +G L WA QGV +LN+
Sbjct: 99 YHGKGQAHGLSFSVKKGVSPPPSLINIYKELETDIEGFKRPLKNGFLEPWARQGVFLLNA 158
Query: 383 VLTVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVIQ 559
VLTV+ TPNSHK+ GW + TDAV++ L+K++ +VFILWG +AQKK K HLV++
Sbjct: 159 VLTVEEATPNSHKDFGWADFTDAVLKILSKQDQPIVFILWGGFAQKKEKLFTNKNHLVLK 218
Query: 560 CAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670
HPSPLS F G K FS++N +LKSK I EIDWK
Sbjct: 219 SGHPSPLSI-KHFIGCKHFSKSNEFLKSKGIEEIDWK 254
>sp|Q8ZD85|UNG_YERPE Uracil-DNA glycosylase (UDG)
Length = 228
Score = 226 bits (575), Expect = 7e-59
Identities = 111/216 (51%), Positives = 148/216 (68%), Gaps = 2/216 (0%)
Frame = +2
Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 205
+W +++ E YFK +A++ E ++ I+PP+K +F+ LTEL VKVVILGQDP
Sbjct: 6 TWHDVIGQEKEQPYFKDTLAYVAAERRAGKTIYPPQKDIFNAFRLTELDQVKVVILGQDP 65
Query: 206 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 385
YHG QAHGL+FSVL P SL NIY EL TDI GF+ P+HG L +WA QGVL+LN+V
Sbjct: 66 YHGPNQAHGLSFSVLPGVPAPPSLGNIYKELVTDIPGFQRPNHGFLQSWAEQGVLLLNTV 125
Query: 386 LTVKAGTPNSHKEKGWENLTDAVIRHLNK-KENLVFILWGKYAQKKCASLNRKKHLVIQC 562
LTV+AG +SH GWE TD VI LN+ +E ++F+LWG +AQKK +N ++H +++
Sbjct: 126 LTVEAGKAHSHANLGWETFTDKVIAALNEHREGVIFMLWGSHAQKKGRIINTERHYILKA 185
Query: 563 AHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670
HPSPLSAH GF G K FS+AN L+ + IDW+
Sbjct: 186 PHPSPLSAHRGFLGCKHFSQANQLLQQQNQQPIDWQ 221
>sp|Q9KPK8|UNG_VIBCH Uracil-DNA glycosylase (UDG)
Length = 226
Score = 224 bits (572), Expect = 2e-58
Identities = 111/216 (51%), Positives = 148/216 (68%), Gaps = 2/216 (0%)
Frame = +2
Query: 29 SWLEILKPEINSTYFKKLMAFLVNEHKSN-VIFPPEKQVFSWTHLTELKNVKVVILGQDP 205
+W +++ E YF++ + F+ ++ ++ VI+PP K VF+ TE +VKVVILGQDP
Sbjct: 6 TWHDVIGNEKQQAYFQQTLQFVESQRQAGKVIYPPAKDVFNAFRFTEFGDVKVVILGQDP 65
Query: 206 YHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLNSV 385
YHG QAHGL FSVL K P SLVNIY EL DI GF+IP HG L +WA QGVL+LN+V
Sbjct: 66 YHGPNQAHGLCFSVLPGVKTPPSLVNIYKELAQDIPGFQIPPHGYLQSWAQQGVLLLNTV 125
Query: 386 LTVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVIQC 562
LTV+ G +SH GWE TD VI LN+ N L+F+LWG +AQKK ++R++H V+
Sbjct: 126 LTVEQGMAHSHANTGWETFTDRVIDALNQHRNGLIFLLWGSHAQKKGQMIDRQRHHVLMA 185
Query: 563 AHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670
HPSPLSAH GF G + FS+ N L+++ IA I+W+
Sbjct: 186 PHPSPLSAHRGFLGCRHFSKTNQLLQAQGIAPINWQ 221
>sp|Q836Z5|UNG_ENTFA Uracil-DNA glycosylase (UDG)
Length = 226
Score = 224 bits (571), Expect = 2e-58
Identities = 113/218 (51%), Positives = 149/218 (68%), Gaps = 1/218 (0%)
Frame = +2
Query: 20 IHPSWLEILKPEINSTYFKKLMAFLVNEHKSNVIFPPEKQVFSWTHLTELKNVKVVILGQ 199
IH SW IL E Y+++L FL E+++ I+P +FS LT + VKVVILGQ
Sbjct: 5 IHNSWQNILSAEFEKPYYQELREFLKKEYQTQTIYPDMYHLFSALELTPFEEVKVVILGQ 64
Query: 200 DPYHGKGQAHGLAFSVLEPCKPPGSLVNIYSELKTDIEGFKIPDHGNLSNWATQGVLMLN 379
DPYHG QAHGL+FSV K P SL NIY EL+ D+ G++ +HG L +WA QGVL+LN
Sbjct: 65 DPYHGPNQAHGLSFSVQPGVKVPPSLANIYKELQADL-GYQPVNHGFLESWAKQGVLLLN 123
Query: 380 SVLTVKAGTPNSHKEKGWENLTDAVIRHLNKKEN-LVFILWGKYAQKKCASLNRKKHLVI 556
+VLTV+AG SH+ KGWE LTD +I LN++E +VFILWG+ AQ+K ++ +H++I
Sbjct: 124 TVLTVRAGQAYSHRGKGWEQLTDVIIEKLNEREKPVVFILWGRPAQEKIKMIDTTRHVII 183
Query: 557 QCAHPSPLSAHAGFFGSKCFSRANAYLKSKEIAEIDWK 670
+ HPSPLSAH GFFGS+ FS+ANA L+ IDW+
Sbjct: 184 KSPHPSPLSAHRGFFGSRPFSQANAALERLGETPIDWQ 221
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,257,196
Number of Sequences: 369166
Number of extensions: 1736230
Number of successful extensions: 4433
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4063
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4152
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7212136400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)