Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00767 (1810 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P29844|HSP7C_DROME Heat shock 70 kDa protein cognate 3 p... 710 0.0 sp|Q90593|GRP78_CHICK 78 kDa glucose-regulated protein prec... 696 0.0 sp|Q16956|GRP78_APLCA 78 kDa glucose-regulated protein prec... 695 0.0 sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein prec... 694 0.0 sp|P20029|GRP78_MOUSE 78 kDa glucose-regulated protein prec... 693 0.0 sp|P07823|GRP78_MESAU 78 kDa glucose-regulated protein prec... 693 0.0 sp|P06761|GRP78_RAT 78 kDa glucose-regulated protein precur... 693 0.0 sp|P19208|HSP7C_CAEBR Heat shock 70 kDa protein C precursor 693 0.0 sp|Q91883|GRP78_XENLA 78 kDa glucose-regulated protein prec... 691 0.0 sp|P27420|HSP7C_CAEEL Heat shock 70 kDa protein C precursor 689 0.0
>sp|P29844|HSP7C_DROME Heat shock 70 kDa protein cognate 3 precursor (78 kDa glucose regulated protein homolog) (GRP 78) (Heat shock protein cognate 72) Length = 656 Score = 710 bits (1833), Expect = 0.0 Identities = 375/582 (64%), Positives = 425/582 (73%) Frame = +3 Query: 60 ISVILLPFIVGLIYSNKETEEKPKDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQ 239 + + +L +V + + E+K KDK L GTVIGIDLGTTYSCVG++K GRVEII NDQ Sbjct: 1 MKLCILLAVVAFVGLSLGEEKKEKDKEL--GTVIGIDLGTTYSCVGVYKNGRVEIIANDQ 58 Query: 240 GNRITPSYIAFTQDGERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPF 419 GNRITPSY+AFT DGERLIGD+AKNQLTTNP NT+FD KRLIGREW+D++VQ DI +PF Sbjct: 59 GNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPF 118 Query: 420 KVVNVDNKPHISVTVKGEEKSFQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFND 599 KVV ++KPHISV K F PEEISAMVLGKMK AE YLGKKVTHAVVTVPAYFND Sbjct: 119 KVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFND 178 Query: 600 AQRQATKNAGIIAGLTVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSL 779 AQRQATK+AG+IAGL V+RIINEPTAAAIAYGLDKK E +LVFDLGGGTFDVSL Sbjct: 179 AQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKK----EGEKNVLVFDLGGGTFDVSL 234 Query: 780 LMIDQGVFEVVATNGDTHLGGEDFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEK 959 L ID GVFEVVATNGDTHLGGEDFDQRV+D+F RA+QKLRREVEK Sbjct: 235 LTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEK 294 Query: 960 AKRALSSVLTTRIEIESLIDGEDFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKT 1139 AKRALS RIEIES +G+DFSETLTRAKFEELN DLF+STL PV+KVL+D + K Sbjct: 295 AKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKK 354 Query: 1140 DIAEIVLVGGSTRIPKVQELVKGFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXX 1319 D+ EIVLVGGSTRIPKVQ+LVK FF GKEP++GINPDE Sbjct: 355 DVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAI 414 Query: 1320 XXXXXXXXXXGMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVK 1499 G+E GGVM KLI RNT IPT K YEGER + K Sbjct: 415 VLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTK 474 Query: 1500 DNHFLGQFDLTGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLK 1679 DNH LG+FDLTGIPPAPRG+PQIEV+FEIDANGIL+VSAEDKGTGNK+ IVITND+NRL Sbjct: 475 DNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLT 534 Query: 1680 PEDIDKMVXXXXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 1805 PEDID+M+ R+E+R+ELE Y YS+KNQ+ Sbjct: 535 PEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQI 576
>sp|Q90593|GRP78_CHICK 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) Length = 652 Score = 696 bits (1796), Expect = 0.0 Identities = 369/560 (65%), Positives = 411/560 (73%), Gaps = 1/560 (0%) Frame = +3 Query: 129 KDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAFTQDGERLIGDSA 308 ++K D GTV+GIDLGTTYSCVG+FK GRVEII NDQGNRITPSY+AFT +GERLIGD+A Sbjct: 19 EEKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAA 78 Query: 309 KNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVVNVDNKPHISVTV-KGEEKSF 485 KNQLT+NP NT+FD KRLIGR W D SVQ+DI + PFKVV KPHI V V G+ K+F Sbjct: 79 KNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVVEKKAKPHIQVDVGGGQTKTF 138 Query: 486 QPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAGIIAGLTVLRIIN 665 PEEISAMVL KMK AE YLGKKVTHAVVTVPAYFNDAQRQATK+AG IAGL V+RIIN Sbjct: 139 APEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIIN 198 Query: 666 EPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLMIDQGVFEVVATNGDTHLGGE 845 EPTAAAIAYGLDK+ E ILVFDLGGGTFDVSLL ID GVFEVVATNGDTHLGGE Sbjct: 199 EPTAAAIAYGLDKR----EGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 254 Query: 846 DFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKAKRALSSVLTTRIEIESLIDGE 1025 DFDQRV+++F RA+QKLRREVEKAKRALSS RIEIES +GE Sbjct: 255 DFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGE 314 Query: 1026 DFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTDIAEIVLVGGSTRIPKVQELVK 1205 DFSETLTRAKFEELN DLF+ST+ PV+KVL+D LKK+DI EIVLVGGSTRIPK+Q+LVK Sbjct: 315 DFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVK 374 Query: 1206 GFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMELEGGVMAKL 1385 FFNGKEP++GINPDE G+E GGVM KL Sbjct: 375 EFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKL 434 Query: 1386 INRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDLTGIPPAPRGVPQ 1565 I RNT +PT K YEGER L KDNH LG FDLTGIPPAPRGVPQ Sbjct: 435 IPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQ 494 Query: 1566 IEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXXXXXXXXXXXXXX 1745 IEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV Sbjct: 495 IEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLK 554 Query: 1746 HRIEARSELEQYVYSMKNQL 1805 RI+AR+ELE Y YS+KNQ+ Sbjct: 555 ERIDARNELESYAYSLKNQI 574
>sp|Q16956|GRP78_APLCA 78 kDa glucose-regulated protein precursor (GRP 78) (BiP) (Protein 1603) Length = 667 Score = 695 bits (1793), Expect = 0.0 Identities = 364/571 (63%), Positives = 417/571 (73%) Frame = +3 Query: 93 LIYSNKETEEKPKDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAF 272 L+ ++ + E++ K + GTVIGIDLGTTYSCVG+FK GRV+II NDQGNRITPSY+AF Sbjct: 19 LVRADGDEEDEGDKKKSEVGTVIGIDLGTTYSCVGVFKNGRVDIIANDQGNRITPSYVAF 78 Query: 273 TQDGERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVVNVDNKPHI 452 T DGERLIGD+AKNQLT+NP NTIFDVKRLIGR + D SVQ DI YPFKV N +NKPHI Sbjct: 79 TADGERLIGDAAKNQLTSNPENTIFDVKRLIGRTFDDKSVQHDIKFYPFKVTNANNKPHI 138 Query: 453 SVTVKGEEKSFQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAGI 632 ++SF PEEISAMVL KM+ IAEEYLGKK+T+AVVTVPAYFNDAQRQATK+AG Sbjct: 139 QAATGEGDRSFAPEEISAMVLSKMRDIAEEYLGKKITNAVVTVPAYFNDAQRQATKDAGT 198 Query: 633 IAGLTVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLMIDQGVFEVV 812 IAGL V+RIINEPTAAAIAYGLDKK E ILVFDLGGGTFDVSLL ID GVFEVV Sbjct: 199 IAGLNVMRIINEPTAAAIAYGLDKK----EGEKNILVFDLGGGTFDVSLLTIDNGVFEVV 254 Query: 813 ATNGDTHLGGEDFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKAKRALSSVLTT 992 +TNGDTHLGGEDFDQRV+++F RA+QKLRREVEKAKRALSS Sbjct: 255 STNGDTHLGGEDFDQRVMEHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSSAHQV 314 Query: 993 RIEIESLIDGEDFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTDIAEIVLVGGS 1172 R+EIES DGEDFSE+LTRAKFEELN DLF+ST+ PV++VL+D LK DI EIVLVGGS Sbjct: 315 RLEIESFFDGEDFSESLTRAKFEELNMDLFRSTMKPVKQVLEDADLKTDDIDEIVLVGGS 374 Query: 1173 TRIPKVQELVKGFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXG 1352 TRIPKVQ+LVK +FNGKEP++GINPDE G Sbjct: 375 TRIPKVQQLVKEYFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEDTGDLVLLDVNPLTMG 434 Query: 1353 MELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDLT 1532 +E GGVM KLI RNT IPT K YEGER + KDNH LG+FDLT Sbjct: 435 IETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERSMTKDNHLLGKFDLT 494 Query: 1533 GIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXXX 1712 GIPPAPRGVPQIEVTFEID NGILKV+AEDKGTG+K IVI ND+NRL PEDI++M+ Sbjct: 495 GIPPAPRGVPQIEVTFEIDVNGILKVTAEDKGTGSKNQIVIQNDQNRLSPEDIERMINDA 554 Query: 1713 XXXXXXXXXXXHRIEARSELEQYVYSMKNQL 1805 +++A++ELE Y YS+KNQ+ Sbjct: 555 EKYADEDKKVKEKVDAKNELESYAYSLKNQI 585
>sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+) binding protein grp78) Length = 654 Score = 694 bits (1790), Expect = 0.0 Identities = 371/572 (64%), Positives = 414/572 (72%), Gaps = 1/572 (0%) Frame = +3 Query: 93 LIYSNKETEEKPKDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAF 272 L+ S EE+ DK D GTV+GIDLGTTYSCVG+FK GRVEII NDQGNRITPSY+AF Sbjct: 11 LLLSAARAEEE--DKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAF 68 Query: 273 TQDGERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVVNVDNKPHI 452 T +GERLIGD+AKNQLT+NP NT+FD KRLIGR W D SVQ+DI PFKVV KP+I Sbjct: 69 TPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYI 128 Query: 453 SVTV-KGEEKSFQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAG 629 V + G+ K+F PEEISAMVL KMK AE YLGKKVTHAVVTVPAYFNDAQRQATK+AG Sbjct: 129 QVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAG 188 Query: 630 IIAGLTVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLMIDQGVFEV 809 IAGL V+RIINEPTAAAIAYGLDK+ E ILVFDLGGGTFDVSLL ID GVFEV Sbjct: 189 TIAGLNVMRIINEPTAAAIAYGLDKR----EGEKNILVFDLGGGTFDVSLLTIDNGVFEV 244 Query: 810 VATNGDTHLGGEDFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKAKRALSSVLT 989 VATNGDTHLGGEDFDQRV+++F RA+QKLRREVEKAKRALSS Sbjct: 245 VATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQ 304 Query: 990 TRIEIESLIDGEDFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTDIAEIVLVGG 1169 RIEIES +GEDFSETLTRAKFEELN DLF+ST+ PV+KVL+D LKK+DI EIVLVGG Sbjct: 305 ARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGG 364 Query: 1170 STRIPKVQELVKGFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1349 STRIPK+Q+LVK FFNGKEP++GINPDE Sbjct: 365 STRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTL 424 Query: 1350 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 1529 G+E GGVM KLI RNT +PT K YEGER L KDNH LG FDL Sbjct: 425 GIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDL 484 Query: 1530 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 1709 TGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV Sbjct: 485 TGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVND 544 Query: 1710 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 1805 RI+ R+ELE Y YS+KNQ+ Sbjct: 545 AEKFAEEDKKLKERIDTRNELESYAYSLKNQI 576
>sp|P20029|GRP78_MOUSE 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) Length = 655 Score = 693 bits (1788), Expect = 0.0 Identities = 367/560 (65%), Positives = 409/560 (73%), Gaps = 1/560 (0%) Frame = +3 Query: 129 KDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAFTQDGERLIGDSA 308 +DK D GTV+GIDLGTTYSCVG+FK GRVEII NDQGNRITPSY+AFT +GERLIGD+A Sbjct: 22 EDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAA 81 Query: 309 KNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVVNVDNKPHISVTVKG-EEKSF 485 KNQLT+NP NT+FD KRLIGR W D SVQ+DI PFKVV KP+I V + G + K+F Sbjct: 82 KNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTF 141 Query: 486 QPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAGIIAGLTVLRIIN 665 PEEISAMVL KMK AE YLGKKVTHAVVTVPAYFNDAQRQATK+AG IAGL V+RIIN Sbjct: 142 APEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIIN 201 Query: 666 EPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLMIDQGVFEVVATNGDTHLGGE 845 EPTAAAIAYGLDK+ E ILVFDLGGGTFDVSLL ID GVFEVVATNGDTHLGGE Sbjct: 202 EPTAAAIAYGLDKREG----EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 257 Query: 846 DFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKAKRALSSVLTTRIEIESLIDGE 1025 DFDQRV+++F RA+QKLRREVEKAKRALSS RIEIES +GE Sbjct: 258 DFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGE 317 Query: 1026 DFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTDIAEIVLVGGSTRIPKVQELVK 1205 DFSETLTRAKFEELN DLF+ST+ PV+KVL+D LKK+DI EIVLVGGSTRIPK+Q+LVK Sbjct: 318 DFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVK 377 Query: 1206 GFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMELEGGVMAKL 1385 FFNGKEP++GINPDE G+E GGVM KL Sbjct: 378 EFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKL 437 Query: 1386 INRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDLTGIPPAPRGVPQ 1565 I RNT +PT K YEGER L KDNH LG FDLTGIPPAPRGVPQ Sbjct: 438 IPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQ 497 Query: 1566 IEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXXXXXXXXXXXXXX 1745 IEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV Sbjct: 498 IEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLK 557 Query: 1746 HRIEARSELEQYVYSMKNQL 1805 RI+ R+ELE Y YS+KNQ+ Sbjct: 558 ERIDTRNELESYAYSLKNQI 577
>sp|P07823|GRP78_MESAU 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) Length = 654 Score = 693 bits (1788), Expect = 0.0 Identities = 367/560 (65%), Positives = 409/560 (73%), Gaps = 1/560 (0%) Frame = +3 Query: 129 KDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAFTQDGERLIGDSA 308 +DK D GTV+GIDLGTTYSCVG+FK GRVEII NDQGNRITPSY+AFT +GERLIGD+A Sbjct: 21 EDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAA 80 Query: 309 KNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVVNVDNKPHISVTVKG-EEKSF 485 KNQLT+NP NT+FD KRLIGR W D SVQ+DI PFKVV KP+I V + G + K+F Sbjct: 81 KNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTF 140 Query: 486 QPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAGIIAGLTVLRIIN 665 PEEISAMVL KMK AE YLGKKVTHAVVTVPAYFNDAQRQATK+AG IAGL V+RIIN Sbjct: 141 APEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIIN 200 Query: 666 EPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLMIDQGVFEVVATNGDTHLGGE 845 EPTAAAIAYGLDK+ E ILVFDLGGGTFDVSLL ID GVFEVVATNGDTHLGGE Sbjct: 201 EPTAAAIAYGLDKREG----EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 256 Query: 846 DFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKAKRALSSVLTTRIEIESLIDGE 1025 DFDQRV+++F RA+QKLRREVEKAKRALSS RIEIES +GE Sbjct: 257 DFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGE 316 Query: 1026 DFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTDIAEIVLVGGSTRIPKVQELVK 1205 DFSETLTRAKFEELN DLF+ST+ PV+KVL+D LKK+DI EIVLVGGSTRIPK+Q+LVK Sbjct: 317 DFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVK 376 Query: 1206 GFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMELEGGVMAKL 1385 FFNGKEP++GINPDE G+E GGVM KL Sbjct: 377 EFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKL 436 Query: 1386 INRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDLTGIPPAPRGVPQ 1565 I RNT +PT K YEGER L KDNH LG FDLTGIPPAPRGVPQ Sbjct: 437 IPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQ 496 Query: 1566 IEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXXXXXXXXXXXXXX 1745 IEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV Sbjct: 497 IEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLK 556 Query: 1746 HRIEARSELEQYVYSMKNQL 1805 RI+ R+ELE Y YS+KNQ+ Sbjct: 557 ERIDTRNELESYAYSLKNQI 576
>sp|P06761|GRP78_RAT 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) (Steroidogenesis-activator polypeptide) Length = 654 Score = 693 bits (1788), Expect = 0.0 Identities = 367/560 (65%), Positives = 409/560 (73%), Gaps = 1/560 (0%) Frame = +3 Query: 129 KDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAFTQDGERLIGDSA 308 +DK D GTV+GIDLGTTYSCVG+FK GRVEII NDQGNRITPSY+AFT +GERLIGD+A Sbjct: 21 EDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAA 80 Query: 309 KNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVVNVDNKPHISVTVKG-EEKSF 485 KNQLT+NP NT+FD KRLIGR W D SVQ+DI PFKVV KP+I V + G + K+F Sbjct: 81 KNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTF 140 Query: 486 QPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAGIIAGLTVLRIIN 665 PEEISAMVL KMK AE YLGKKVTHAVVTVPAYFNDAQRQATK+AG IAGL V+RIIN Sbjct: 141 APEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIIN 200 Query: 666 EPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLMIDQGVFEVVATNGDTHLGGE 845 EPTAAAIAYGLDK+ E ILVFDLGGGTFDVSLL ID GVFEVVATNGDTHLGGE Sbjct: 201 EPTAAAIAYGLDKREG----EKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGE 256 Query: 846 DFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKAKRALSSVLTTRIEIESLIDGE 1025 DFDQRV+++F RA+QKLRREVEKAKRALSS RIEIES +GE Sbjct: 257 DFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGE 316 Query: 1026 DFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTDIAEIVLVGGSTRIPKVQELVK 1205 DFSETLTRAKFEELN DLF+ST+ PV+KVL+D LKK+DI EIVLVGGSTRIPK+Q+LVK Sbjct: 317 DFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVK 376 Query: 1206 GFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGMELEGGVMAKL 1385 FFNGKEP++GINPDE G+E GGVM KL Sbjct: 377 EFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKL 436 Query: 1386 INRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDLTGIPPAPRGVPQ 1565 I RNT +PT K YEGER L KDNH LG FDLTGIPPAPRGVPQ Sbjct: 437 IPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQ 496 Query: 1566 IEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXXXXXXXXXXXXXX 1745 IEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV Sbjct: 497 IEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLK 556 Query: 1746 HRIEARSELEQYVYSMKNQL 1805 RI+ R+ELE Y YS+KNQ+ Sbjct: 557 ERIDTRNELESYAYSLKNQI 576
>sp|P19208|HSP7C_CAEBR Heat shock 70 kDa protein C precursor Length = 661 Score = 693 bits (1788), Expect = 0.0 Identities = 366/581 (62%), Positives = 420/581 (72%), Gaps = 6/581 (1%) Frame = +3 Query: 81 FIVGLIYSNK-----ETEEKPKDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGN 245 F++GLI E EEK + K YGT+IGIDLGTTYSCVG++K GRVEII NDQGN Sbjct: 5 FLLGLIALTAVSVYCEEEEKTEKKETKYGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGN 64 Query: 246 RITPSYIAFT-QDGERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFK 422 RITPSY+AF+ + G+RLIGD+AKNQLT NP NTIFD KRLIGR++ D +VQ DI H+PFK Sbjct: 65 RITPSYVAFSGEQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFK 124 Query: 423 VVNVDNKPHISVTVKGEEKSFQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDA 602 V++ NKP + V V + K F PEE+SAMVL KMK IAE YLGK+V HAVVTVPAYFNDA Sbjct: 125 VLDKSNKPSVEVKVGADNKQFTPEEVSAMVLVKMKEIAESYLGKEVKHAVVTVPAYFNDA 184 Query: 603 QRQATKNAGIIAGLTVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLL 782 QRQATK+AG IAGL V+RIINEPTAAAIAYGLDKK E ILVFDLGGGTFDVS+L Sbjct: 185 QRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKK----DGERNILVFDLGGGTFDVSML 240 Query: 783 MIDQGVFEVVATNGDTHLGGEDFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKA 962 ID GVFEV+ATNGDTHLGGEDFDQRV++YF RA+QKLRREVEKA Sbjct: 241 TIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKA 300 Query: 963 KRALSSVLTTRIEIESLIDGEDFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTD 1142 KRALS+ T++EIESL DGEDFSETLTRAKFEELN DLF++TL PV+KVL+D LKK D Sbjct: 301 KRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKDD 360 Query: 1143 IAEIVLVGGSTRIPKVQELVKGFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXX 1322 + EIVLVGGSTRIPKVQ+L+K FFNGKEP++GINPDE Sbjct: 361 VHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIV 420 Query: 1323 XXXXXXXXXGMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKD 1502 G+E GGVM KLI+RNT IPT K +EGER + KD Sbjct: 421 LLDVNPLTMGIETVGGVMTKLISRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKD 480 Query: 1503 NHFLGQFDLTGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKP 1682 NH LG+FDLTGIPPAPRGVPQIEVTFEID NGIL V+AEDKGTGNK I ITND+NRL P Sbjct: 481 NHQLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSP 540 Query: 1683 EDIDKMVXXXXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 1805 EDI++M+ + EAR+ELE Y YS+KNQ+ Sbjct: 541 EDIERMINDAEKFAEDDKKVKEKAEARNELESYAYSLKNQI 581
>sp|Q91883|GRP78_XENLA 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) Length = 658 Score = 691 bits (1783), Expect = 0.0 Identities = 366/575 (63%), Positives = 412/575 (71%) Frame = +3 Query: 81 FIVGLIYSNKETEEKPKDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPS 260 F + L+ S DK D GTV+GIDLGTTYSCVG+FK GRVEII NDQGNRITPS Sbjct: 7 FALVLLVSASVFASDDDDKKDDIGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPS 66 Query: 261 YIAFTQDGERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVVNVDN 440 Y+AFT +GERLIGD+AKNQLT+NP NT+FD KRLIGR W D SVQ+DI + PFKV+ Sbjct: 67 YVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIEKKT 126 Query: 441 KPHISVTVKGEEKSFQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATK 620 KP+I V + + K+F PEEISAMVL KMK AE YLG+KVTHAVVTVPAYFNDAQRQATK Sbjct: 127 KPYIEVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGRKVTHAVVTVPAYFNDAQRQATK 186 Query: 621 NAGIIAGLTVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLMIDQGV 800 +AG IAGL V+RIINEPTAAAIAYGLDKK E ILVFDLGGGTFDVSLL ID GV Sbjct: 187 DAGTIAGLNVMRIINEPTAAAIAYGLDKK----EGEKNILVFDLGGGTFDVSLLTIDNGV 242 Query: 801 FEVVATNGDTHLGGEDFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKAKRALSS 980 FEVVATNGDTHLGGEDFDQRV+++F RA+QKLRREVEKAKRALS+ Sbjct: 243 FEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRADKRAVQKLRREVEKAKRALSA 302 Query: 981 VLTTRIEIESLIDGEDFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTDIAEIVL 1160 +RIEIES +GEDFSETLTRAKFEELN DLF+ST+ PV+KVL D LKK+DI EIVL Sbjct: 303 QHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDSDLKKSDIDEIVL 362 Query: 1161 VGGSTRIPKVQELVKGFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1340 VGGSTRIPK+Q+LVK FNGKEP++GINPDE Sbjct: 363 VGGSTRIPKIQQLVKELFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCP 422 Query: 1341 XXXGMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQ 1520 G+E GGVM KLI RNT +PT K YEGER L KDNH LG Sbjct: 423 LTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGT 482 Query: 1521 FDLTGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKM 1700 FDLTGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++M Sbjct: 483 FDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERM 542 Query: 1701 VXXXXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 1805 V RI+ R+ELE Y YS+KNQ+ Sbjct: 543 VTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQI 577
>sp|P27420|HSP7C_CAEEL Heat shock 70 kDa protein C precursor Length = 661 Score = 689 bits (1779), Expect = 0.0 Identities = 364/581 (62%), Positives = 420/581 (72%), Gaps = 6/581 (1%) Frame = +3 Query: 81 FIVGLIYSNK-----ETEEKPKDKILDYGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGN 245 F++GLI + E EEK + K YGT+IGIDLGTTYSCVG++K GRVEII NDQGN Sbjct: 5 FLLGLIALSAVSVYCEEEEKTEKKETKYGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGN 64 Query: 246 RITPSYIAFTQD-GERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFK 422 RITPSY+AF+ D G+RLIGD+AKNQLT NP NTIFD KRLIGR++ D +VQ DI H+PFK Sbjct: 65 RITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFK 124 Query: 423 VVNVDNKPHISVTVKGEEKSFQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDA 602 V++ NKP + V V + K F PEE+SAMVL KMK IAE YLGK+V +AVVTVPAYFNDA Sbjct: 125 VIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDA 184 Query: 603 QRQATKNAGIIAGLTVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLL 782 QRQATK+AG IAGL V+RIINEPTAAAIAYGLDKK E ILVFDLGGGTFDVS+L Sbjct: 185 QRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKK----DGERNILVFDLGGGTFDVSML 240 Query: 783 MIDQGVFEVVATNGDTHLGGEDFDQRVIDYFSXXXXXXXXXXXXXXXRAIQKLRREVEKA 962 ID GVFEV+ATNGDTHLGGEDFDQRV++YF RA+QKLRREVEKA Sbjct: 241 TIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKA 300 Query: 963 KRALSSVLTTRIEIESLIDGEDFSETLTRAKFEELNADLFKSTLIPVEKVLQDGGLKKTD 1142 KRALS+ T++EIESL DGEDFSETLTRAKFEELN DLF++TL PV+KVL+D LKK D Sbjct: 301 KRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKDD 360 Query: 1143 IAEIVLVGGSTRIPKVQELVKGFFNGKEPNKGINPDEXXXXXXXXXXXXXXXXXXXXXXX 1322 + EIVLVGGSTRIPKVQ+L+K FFNGKEP++GINPDE Sbjct: 361 VHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIV 420 Query: 1323 XXXXXXXXXGMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKD 1502 G+E GGVM KLI RNT IPT K +EGER + KD Sbjct: 421 LLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKD 480 Query: 1503 NHFLGQFDLTGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKP 1682 NH LG+FDLTG+PPAPRGVPQIEVTFEID NGIL V+AEDKGTGNK I ITND+NRL P Sbjct: 481 NHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSP 540 Query: 1683 EDIDKMVXXXXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 1805 EDI++M+ + EAR+ELE Y Y++KNQ+ Sbjct: 541 EDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQI 581
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 179,441,169 Number of Sequences: 369166 Number of extensions: 3503223 Number of successful extensions: 12543 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 9426 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 10165 length of database: 68,354,980 effective HSP length: 116 effective length of database: 46,925,720 effective search space used: 22805899920 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)