Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_C09
(561 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29844|HSP7C_DROME Heat shock 70 kDa protein cognate 3 p... 181 8e-46
sp|Q90593|GRP78_CHICK 78 kDa glucose-regulated protein prec... 176 4e-44
sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein prec... 174 1e-43
sp|P20029|GRP78_MOUSE 78 kDa glucose-regulated protein prec... 174 1e-43
sp|Q16956|GRP78_APLCA 78 kDa glucose-regulated protein prec... 174 1e-43
sp|P07823|GRP78_MESAU 78 kDa glucose-regulated protein prec... 174 1e-43
sp|P06761|GRP78_RAT 78 kDa glucose-regulated protein precur... 174 1e-43
sp|Q91883|GRP78_XENLA 78 kDa glucose-regulated protein prec... 174 1e-43
sp|P19208|HSP7C_CAEBR Heat shock 70 kDa protein C precursor 173 2e-43
sp|P34935|GRP78_PIG 78 kDa glucose-regulated protein (GRP 7... 172 4e-43
>sp|P29844|HSP7C_DROME Heat shock 70 kDa protein cognate 3 precursor (78 kDa glucose
regulated protein homolog) (GRP 78) (Heat shock protein
cognate 72)
Length = 656
Score = 181 bits (460), Expect = 8e-46
Identities = 91/152 (59%), Positives = 106/152 (69%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT IPT K YEGER + KDNH LG+FDL
Sbjct: 425 GIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDL 484
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRG+PQIEV+FEIDANGIL+VSAEDKGTGNK+ IVITND+NRL PEDID+M+
Sbjct: 485 TGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRD 544
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
R+E+R+ELE Y YS+KNQ+
Sbjct: 545 AEKFADEDKKLKERVESRNELESYAYSLKNQI 576
>sp|Q90593|GRP78_CHICK 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin
heavy chain binding protein) (BiP)
Length = 652
Score = 176 bits (446), Expect = 4e-44
Identities = 90/152 (59%), Positives = 102/152 (67%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT +PT K YEGER L KDNH LG FDL
Sbjct: 423 GIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDL 482
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV
Sbjct: 483 TGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVND 542
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
RI+AR+ELE Y YS+KNQ+
Sbjct: 543 AEKFAEEDKKLKERIDARNELESYAYSLKNQI 574
>sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin
heavy chain binding protein) (BiP) (Endoplasmic
reticulum lumenal Ca(2+) binding protein grp78)
Length = 654
Score = 174 bits (442), Expect = 1e-43
Identities = 89/152 (58%), Positives = 101/152 (66%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT +PT K YEGER L KDNH LG FDL
Sbjct: 425 GIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDL 484
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV
Sbjct: 485 TGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVND 544
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
RI+ R+ELE Y YS+KNQ+
Sbjct: 545 AEKFAEEDKKLKERIDTRNELESYAYSLKNQI 576
>sp|P20029|GRP78_MOUSE 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin
heavy chain binding protein) (BiP)
Length = 655
Score = 174 bits (442), Expect = 1e-43
Identities = 89/152 (58%), Positives = 101/152 (66%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT +PT K YEGER L KDNH LG FDL
Sbjct: 426 GIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDL 485
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV
Sbjct: 486 TGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVND 545
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
RI+ R+ELE Y YS+KNQ+
Sbjct: 546 AEKFAEEDKKLKERIDTRNELESYAYSLKNQI 577
>sp|Q16956|GRP78_APLCA 78 kDa glucose-regulated protein precursor (GRP 78) (BiP) (Protein
1603)
Length = 667
Score = 174 bits (442), Expect = 1e-43
Identities = 87/152 (57%), Positives = 103/152 (67%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT IPT K YEGER + KDNH LG+FDL
Sbjct: 434 GIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERSMTKDNHLLGKFDL 493
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGILKV+AEDKGTG+K IVI ND+NRL PEDI++M+
Sbjct: 494 TGIPPAPRGVPQIEVTFEIDVNGILKVTAEDKGTGSKNQIVIQNDQNRLSPEDIERMIND 553
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
+++A++ELE Y YS+KNQ+
Sbjct: 554 AEKYADEDKKVKEKVDAKNELESYAYSLKNQI 585
>sp|P07823|GRP78_MESAU 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin
heavy chain binding protein) (BiP)
Length = 654
Score = 174 bits (442), Expect = 1e-43
Identities = 89/152 (58%), Positives = 101/152 (66%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT +PT K YEGER L KDNH LG FDL
Sbjct: 425 GIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDL 484
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV
Sbjct: 485 TGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVND 544
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
RI+ R+ELE Y YS+KNQ+
Sbjct: 545 AEKFAEEDKKLKERIDTRNELESYAYSLKNQI 576
>sp|P06761|GRP78_RAT 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin
heavy chain binding protein) (BiP)
(Steroidogenesis-activator polypeptide)
Length = 654
Score = 174 bits (442), Expect = 1e-43
Identities = 89/152 (58%), Positives = 101/152 (66%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT +PT K YEGER L KDNH LG FDL
Sbjct: 425 GIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDL 484
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV
Sbjct: 485 TGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVND 544
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
RI+ R+ELE Y YS+KNQ+
Sbjct: 545 AEKFAEEDKKLKERIDTRNELESYAYSLKNQI 576
>sp|Q91883|GRP78_XENLA 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin
heavy chain binding protein) (BiP)
Length = 658
Score = 174 bits (442), Expect = 1e-43
Identities = 89/152 (58%), Positives = 101/152 (66%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT +PT K YEGER L KDNH LG FDL
Sbjct: 426 GIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDL 485
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV
Sbjct: 486 TGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTD 545
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
RI+ R+ELE Y YS+KNQ+
Sbjct: 546 AEKFAEEDKKLKERIDTRNELESYAYSLKNQI 577
>sp|P19208|HSP7C_CAEBR Heat shock 70 kDa protein C precursor
Length = 661
Score = 173 bits (439), Expect = 2e-43
Identities = 88/152 (57%), Positives = 102/152 (67%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI+RNT IPT K +EGER + KDNH LG+FDL
Sbjct: 430 GIETVGGVMTKLISRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDL 489
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGIL V+AEDKGTGNK I ITND+NRL PEDI++M+
Sbjct: 490 TGIPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMIND 549
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
+ EAR+ELE Y YS+KNQ+
Sbjct: 550 AEKFAEDDKKVKEKAEARNELESYAYSLKNQI 581
>sp|P34935|GRP78_PIG 78 kDa glucose-regulated protein (GRP 78) (Immunoglobulin heavy
chain binding protein) (BiP)
Length = 262
Score = 172 bits (437), Expect = 4e-43
Identities = 88/152 (57%), Positives = 100/152 (65%)
Frame = +2
Query: 101 GMELEGGVMAKLINRNTPIPTIKKXXXXXXXXXXXXXXXXXYEGERQLVKDNHFLGQFDL 280
G+E GGVM KLI RNT +PT K YEGER L KDNH LG FDL
Sbjct: 69 GIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDL 128
Query: 281 TGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMVXX 460
TGIPPAPRGVPQIEVTFEID NGIL+V+AEDKGTGNK I ITND+NRL PE+I++MV
Sbjct: 129 TGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVND 188
Query: 461 XXXXXXXXXXXXHRIEARSELEQYVYSMKNQL 556
RI+ R+ELE Y Y +KNQ+
Sbjct: 189 AEKFAEEDKKLKERIDTRNELESYAYCLKNQI 220
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,788,595
Number of Sequences: 369166
Number of extensions: 1042194
Number of successful extensions: 3589
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3086
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3142
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4029688280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)