Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00628 (1069 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9NXZ2|DDX43_HUMAN Probable ATP-dependent RNA helicase D... 197 3e-50 sp|P46942|DB10_NICSY RNA helicase-like protein DB10 179 9e-45 sp|Q92841|DDX17_HUMAN Probable ATP-dependent helicase DDX17... 175 2e-43 sp|Q6FLF3|DBP2_CANGA Probable ATP-dependent RNA helicase DBP2 175 2e-43 sp|Q86TM3|DDX53_HUMAN Probable ATP-dependent RNA helicase D... 175 2e-43 sp|Q501J6|DDX17_MOUSE Probable ATP-dependent helicase DDX17... 175 2e-43 sp|P24783|DBP2_YEAST Probable ATP-dependent RNA helicase DB... 174 4e-43 sp|P24782|DBP2_SCHPO Probable ATP-dependent RNA helicase DB... 174 5e-43 sp|P19109|RM62_DROME ATP-dependent RNA helicase P62 173 9e-43 sp|Q6CIV2|DBP2_KLULA Probable ATP-dependent RNA helicase DBP2 172 1e-42
>sp|Q9NXZ2|DDX43_HUMAN Probable ATP-dependent RNA helicase DDX43 (DEAD-box protein 43) (DEAD-box protein HAGE) (Helical antigen) Length = 648 Score = 197 bits (502), Expect = 3e-50 Identities = 105/243 (43%), Positives = 152/243 (62%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEAD+MLDMGFE Q++ ++ VR RQTVMTSATWP V R+A +++K P+ V VGT Sbjct: 393 LVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGT 452 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKAQCSDLAFELYLKRS 361 LDL A +V+Q++ +K + L + DK+I+FV+RKA L+ +L L Sbjct: 453 LDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLIL--- 509 Query: 362 KGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVINY 541 G + +HGD +Q++RE AL+ ++G I+IATD+ASRGLD+ D+T V N+ Sbjct: 510 -------GNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNF 562 Query: 542 DFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQLMK 721 DFP+NIEEYVH + T + + DW A+ELI ILE A+Q +P+ L + + Sbjct: 563 DFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAE 622 Query: 722 QHQ 730 + + Sbjct: 623 RFE 625
>sp|P46942|DB10_NICSY RNA helicase-like protein DB10 Length = 607 Score = 179 bits (455), Expect = 9e-45 Identities = 104/233 (44%), Positives = 142/233 (60%), Gaps = 1/233 (0%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEADRMLDMGFE Q+ ++ V QRQT+M +ATWP GV++IA + N +QVN+G Sbjct: 295 LVLDEADRMLDMGFEPQIRKIVKEVPVQRQTLMYTATWPKGVRKIAADLLVNSVQVNIGN 354 Query: 182 LD-LNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKAQCSDLAFELYLKR 358 +D L A ++ QH+E V +K +R+ +IL +P KIIIF + K C L+ L R Sbjct: 355 VDELVANKSITQHIEVVLPMEKQRRVEQILRSKEPGSKIIIFCSTKKMCDQLSRNL--TR 412 Query: 359 SKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVIN 538 + G A IHGD Q ER+ L R+G +++ATDVA+RGLDI D+ VIN Sbjct: 413 NFG---------AAAIHGDKSQGERDYVLSQFRAGRSPVLVATDVAARGLDIKDIRVVIN 463 Query: 539 YDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVP 697 YDFP IE+YVH A+TF + D +A +L+++LE A+Q VP Sbjct: 464 YDFPTGIEDYVHRIGRTGRAGASGLAYTFFSDQDSKHALDLVKVLEGANQCVP 516
>sp|Q92841|DDX17_HUMAN Probable ATP-dependent helicase DDX17 (DEAD-box protein 17) (RNA-dependent helicase p72) (DEAD-box protein p72) Length = 650 Score = 175 bits (444), Expect = 2e-43 Identities = 101/241 (41%), Positives = 143/241 (59%), Gaps = 2/241 (0%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A +++ Q+NVG Sbjct: 243 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGN 302 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQCSDLAFELYLK 355 L+L+A H + Q V+ +K +L++++ EI + E+K IIFV K +C DL + Sbjct: 303 LELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMR-- 360 Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535 + A IHGD Q ER+ L RSG I+IATDVASRGLD+ D+ VI Sbjct: 361 --------RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVI 412 Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715 NYD+P + E+YVH A+TF + A ELI++LE+A+Q + L QL Sbjct: 413 NYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQL 472 Query: 716 M 718 + Sbjct: 473 V 473
>sp|Q6FLF3|DBP2_CANGA Probable ATP-dependent RNA helicase DBP2 Length = 544 Score = 175 bits (444), Expect = 2e-43 Identities = 102/242 (42%), Positives = 142/242 (58%), Gaps = 2/242 (0%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP VQ++A ++ +PIQV +G+ Sbjct: 261 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVQQLARDYLNDPIQVQIGS 320 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIK--PEDKIIIFVARKAQCSDLAFELYLK 355 L+L A H + Q VE V +K RLV+ L E KI+IF + K C ++ YL+ Sbjct: 321 LELAASHNITQLVEVVSEFEKRDRLVKHLDTASQDKESKILIFASTKRTCDEIT--SYLR 378 Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535 + A IHGD DQ+ER+ L R+G IM+ATDVA+RG+D+ + V+ Sbjct: 379 QD--------GWPALAIHGDKDQRERDWVLNEFRTGNSPIMVATDVAARGIDVKGINFVV 430 Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715 NYD P NIE+YVH A +F + + S A LI I+ +A Q +P+ +L Sbjct: 431 NYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEDNKSLGASLISIMREAKQNIPE---EL 487 Query: 716 MK 721 MK Sbjct: 488 MK 489
>sp|Q86TM3|DDX53_HUMAN Probable ATP-dependent RNA helicase DDX53 (DEAD-box protein 53) (DEAD-box protein CAGE) (Cancer-associated gene protein) Length = 631 Score = 175 bits (444), Expect = 2e-43 Identities = 95/243 (39%), Positives = 150/243 (61%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LV+DEAD+MLDM FE Q+ ++ VR RQTVMTSATWP V+++AL+++K+P+ V VG Sbjct: 373 LVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYVGN 432 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKAQCSDLAFELYLKRS 361 L+L A +TV+Q++ +K E + + P DK+I+FV++K DL+ + ++ Sbjct: 433 LNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQ-- 490 Query: 362 KGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVINY 541 + A +HG+ +Q ++E A++ +SG I+I TD+ SRGLD+ D+T V NY Sbjct: 491 --------GISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNY 542 Query: 542 DFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQLMK 721 DFP+NI+ YVH + T + + D A ELI+IL+ A+Q VP+ L + + Sbjct: 543 DFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAE 602 Query: 722 QHQ 730 Q++ Sbjct: 603 QYK 605
>sp|Q501J6|DDX17_MOUSE Probable ATP-dependent helicase DDX17 (DEAD-box protein 17) Length = 650 Score = 175 bits (444), Expect = 2e-43 Identities = 101/241 (41%), Positives = 143/241 (59%), Gaps = 2/241 (0%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A +++ Q+NVG Sbjct: 243 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGN 302 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQCSDLAFELYLK 355 L+L+A H + Q V+ +K +L++++ EI + E+K IIFV K +C DL + Sbjct: 303 LELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMR-- 360 Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535 + A IHGD Q ER+ L RSG I+IATDVASRGLD+ D+ VI Sbjct: 361 --------RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVI 412 Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715 NYD+P + E+YVH A+TF + A ELI++LE+A+Q + L QL Sbjct: 413 NYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQL 472 Query: 716 M 718 + Sbjct: 473 V 473
>sp|P24783|DBP2_YEAST Probable ATP-dependent RNA helicase DBP2 (p68-like protein) Length = 546 Score = 174 bits (441), Expect = 4e-43 Identities = 100/242 (41%), Positives = 144/242 (59%), Gaps = 2/242 (0%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A ++ +PIQV VG+ Sbjct: 264 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGS 323 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPED--KIIIFVARKAQCSDLAFELYLK 355 L+L+A H + Q VE V +K RL + L ++ K +IF + K C D+ YL+ Sbjct: 324 LELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNEYKTLIFASTKRMCDDIT--KYLR 381 Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535 + A IHGD DQ+ER+ L+ R+G IM+ATDVA+RG+D+ + VI Sbjct: 382 --------EDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVI 433 Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715 NYD P NIE+YVH A +F + + A+LI I+ +A+Q +P P+L Sbjct: 434 NYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIP---PEL 490 Query: 716 MK 721 +K Sbjct: 491 LK 492
>sp|P24782|DBP2_SCHPO Probable ATP-dependent RNA helicase DBP2 (p68-like protein) Length = 550 Score = 174 bits (440), Expect = 5e-43 Identities = 102/242 (42%), Positives = 139/242 (57%), Gaps = 2/242 (0%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEADRMLDMGFE Q+ ++ +R RQTVM SATWP VQR+A ++ + IQV VG+ Sbjct: 273 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTVMFSATWPKEVQRLARDYLNDYIQVTVGS 332 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQCSDLAFELYLK 355 LDL A H ++Q VE V+ DK RL + + E+ ++K++IF K D+ L Sbjct: 333 LDLAASHNIKQIVEVVDNADKRARLGKDIEEVLKDRDNKVLIFTGTKRVADDITRFL--- 389 Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535 R G A IHGD Q ER+ L R+G IM+ATDVASRG+D+ +T V Sbjct: 390 RQDGW-------PALAIHGDKAQDERDWVLNEFRTGKSPIMVATDVASRGIDVKGITHVF 442 Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715 NYDFP N E+YVH A+T+ + A EL+ IL +A Q++ L ++ Sbjct: 443 NYDFPGNTEDYVHRIGRTGRAGAKGTAYTYFTSDNAKQARELVSILSEAKQDIDPKLEEM 502 Query: 716 MK 721 + Sbjct: 503 AR 504
>sp|P19109|RM62_DROME ATP-dependent RNA helicase P62 Length = 719 Score = 173 bits (438), Expect = 9e-43 Identities = 100/244 (40%), Positives = 145/244 (59%), Gaps = 4/244 (1%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A + N IQ+N+G+ Sbjct: 432 LVLDEADRMLDMGFEPQIRKIVSQIRPDRQTLMWSATWPKEVKQLAEDFLGNYIQINIGS 491 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEI----KPEDKIIIFVARKAQCSDLAFELY 349 L+L+A H +RQ V+ + K ++L +LS+I + KIIIFV K + +L + Sbjct: 492 LELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNL---VR 548 Query: 350 LKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTK 529 RS G VR IHGD Q ER+ L+ RSG NI++ATDVA+RGLD+ + Sbjct: 549 FIRSFG-------VRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKY 601 Query: 530 VINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLP 709 VIN+D+P+N E+Y+H +F F K + A L+ +L +A+QE+ L Sbjct: 602 VINFDYPQNSEDYIHRIGRTGRSNTKGTSFAFFTKNNAKQAKALVDVLREANQEINPALE 661 Query: 710 QLMK 721 L + Sbjct: 662 NLAR 665
>sp|Q6CIV2|DBP2_KLULA Probable ATP-dependent RNA helicase DBP2 Length = 554 Score = 172 bits (437), Expect = 1e-42 Identities = 100/237 (42%), Positives = 141/237 (59%), Gaps = 2/237 (0%) Frame = +2 Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181 LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A ++ +PIQV +G+ Sbjct: 264 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLASDYLHDPIQVQIGS 323 Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIK--PEDKIIIFVARKAQCSDLAFELYLK 355 L+L+A HT+ Q VE + +K RL + L + KIIIF + K C ++ L Sbjct: 324 LELSASHTITQIVEVLTDFEKRDRLAKHLETASQDQDSKIIIFASTKRTCDEITSYL--- 380 Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535 R++G A IHGD Q ER+ L RSG IM+ATDVA+RG+D+ + VI Sbjct: 381 RTEGW-------PALAIHGDKAQNERDWVLAEFRSGRSPIMVATDVAARGIDVKGINYVI 433 Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFL 706 NYD P NIE+YVH A +F + + S A LI+I+ +A Q++P+ L Sbjct: 434 NYDMPGNIEDYVHRIGRTGRAGSTGTAISFFTEGNKSLGAALIKIMREAKQDIPEEL 490
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 102,404,265 Number of Sequences: 369166 Number of extensions: 1842344 Number of successful extensions: 5361 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4971 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5130 length of database: 68,354,980 effective HSP length: 112 effective length of database: 47,664,660 effective search space used: 11582512380 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)