Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_016_K02
(796 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NXZ2|DDX43_HUMAN Probable ATP-dependent RNA helicase D... 197 2e-50
sp|P46942|DB10_NICSY RNA helicase-like protein DB10 179 6e-45
sp|Q92841|DDX17_HUMAN Probable ATP-dependent helicase DDX17... 175 1e-43
sp|Q6FLF3|DBP2_CANGA Probable ATP-dependent RNA helicase DBP2 175 1e-43
sp|Q86TM3|DDX53_HUMAN Probable ATP-dependent RNA helicase D... 175 1e-43
sp|Q501J6|DDX17_MOUSE Probable ATP-dependent helicase DDX17... 175 1e-43
sp|P24783|DBP2_YEAST Probable ATP-dependent RNA helicase DB... 174 2e-43
sp|P24782|DBP2_SCHPO Probable ATP-dependent RNA helicase DB... 174 3e-43
sp|P19109|RM62_DROME ATP-dependent RNA helicase P62 173 6e-43
sp|Q6CIV2|DBP2_KLULA Probable ATP-dependent RNA helicase DBP2 172 7e-43
>sp|Q9NXZ2|DDX43_HUMAN Probable ATP-dependent RNA helicase DDX43 (DEAD-box protein 43)
(DEAD-box protein HAGE) (Helical antigen)
Length = 648
Score = 197 bits (502), Expect = 2e-50
Identities = 105/243 (43%), Positives = 152/243 (62%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEAD+MLDMGFE Q++ ++ VR RQTVMTSATWP V R+A +++K P+ V VGT
Sbjct: 393 LVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGT 452
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKAQCSDLAFELYLKRS 361
LDL A +V+Q++ +K + L + DK+I+FV+RKA L+ +L L
Sbjct: 453 LDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLIL--- 509
Query: 362 KGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVINY 541
G + +HGD +Q++RE AL+ ++G I+IATD+ASRGLD+ D+T V N+
Sbjct: 510 -------GNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNF 562
Query: 542 DFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQLMK 721
DFP+NIEEYVH + T + + DW A+ELI ILE A+Q +P+ L + +
Sbjct: 563 DFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAE 622
Query: 722 QHQ 730
+ +
Sbjct: 623 RFE 625
>sp|P46942|DB10_NICSY RNA helicase-like protein DB10
Length = 607
Score = 179 bits (455), Expect = 6e-45
Identities = 104/233 (44%), Positives = 142/233 (60%), Gaps = 1/233 (0%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEADRMLDMGFE Q+ ++ V QRQT+M +ATWP GV++IA + N +QVN+G
Sbjct: 295 LVLDEADRMLDMGFEPQIRKIVKEVPVQRQTLMYTATWPKGVRKIAADLLVNSVQVNIGN 354
Query: 182 LD-LNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKAQCSDLAFELYLKR 358
+D L A ++ QH+E V +K +R+ +IL +P KIIIF + K C L+ L R
Sbjct: 355 VDELVANKSITQHIEVVLPMEKQRRVEQILRSKEPGSKIIIFCSTKKMCDQLSRNL--TR 412
Query: 359 SKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVIN 538
+ G A IHGD Q ER+ L R+G +++ATDVA+RGLDI D+ VIN
Sbjct: 413 NFG---------AAAIHGDKSQGERDYVLSQFRAGRSPVLVATDVAARGLDIKDIRVVIN 463
Query: 539 YDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVP 697
YDFP IE+YVH A+TF + D +A +L+++LE A+Q VP
Sbjct: 464 YDFPTGIEDYVHRIGRTGRAGASGLAYTFFSDQDSKHALDLVKVLEGANQCVP 516
>sp|Q92841|DDX17_HUMAN Probable ATP-dependent helicase DDX17 (DEAD-box protein 17)
(RNA-dependent helicase p72) (DEAD-box protein p72)
Length = 650
Score = 175 bits (444), Expect = 1e-43
Identities = 101/241 (41%), Positives = 143/241 (59%), Gaps = 2/241 (0%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A +++ Q+NVG
Sbjct: 243 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGN 302
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQCSDLAFELYLK 355
L+L+A H + Q V+ +K +L++++ EI + E+K IIFV K +C DL +
Sbjct: 303 LELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMR-- 360
Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535
+ A IHGD Q ER+ L RSG I+IATDVASRGLD+ D+ VI
Sbjct: 361 --------RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVI 412
Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715
NYD+P + E+YVH A+TF + A ELI++LE+A+Q + L QL
Sbjct: 413 NYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQL 472
Query: 716 M 718
+
Sbjct: 473 V 473
>sp|Q6FLF3|DBP2_CANGA Probable ATP-dependent RNA helicase DBP2
Length = 544
Score = 175 bits (444), Expect = 1e-43
Identities = 102/242 (42%), Positives = 142/242 (58%), Gaps = 2/242 (0%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP VQ++A ++ +PIQV +G+
Sbjct: 261 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVQQLARDYLNDPIQVQIGS 320
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIK--PEDKIIIFVARKAQCSDLAFELYLK 355
L+L A H + Q VE V +K RLV+ L E KI+IF + K C ++ YL+
Sbjct: 321 LELAASHNITQLVEVVSEFEKRDRLVKHLDTASQDKESKILIFASTKRTCDEIT--SYLR 378
Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535
+ A IHGD DQ+ER+ L R+G IM+ATDVA+RG+D+ + V+
Sbjct: 379 QD--------GWPALAIHGDKDQRERDWVLNEFRTGNSPIMVATDVAARGIDVKGINFVV 430
Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715
NYD P NIE+YVH A +F + + S A LI I+ +A Q +P+ +L
Sbjct: 431 NYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEDNKSLGASLISIMREAKQNIPE---EL 487
Query: 716 MK 721
MK
Sbjct: 488 MK 489
>sp|Q86TM3|DDX53_HUMAN Probable ATP-dependent RNA helicase DDX53 (DEAD-box protein 53)
(DEAD-box protein CAGE) (Cancer-associated gene protein)
Length = 631
Score = 175 bits (444), Expect = 1e-43
Identities = 95/243 (39%), Positives = 150/243 (61%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LV+DEAD+MLDM FE Q+ ++ VR RQTVMTSATWP V+++AL+++K+P+ V VG
Sbjct: 373 LVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYVGN 432
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKAQCSDLAFELYLKRS 361
L+L A +TV+Q++ +K E + + P DK+I+FV++K DL+ + ++
Sbjct: 433 LNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQ-- 490
Query: 362 KGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVINY 541
+ A +HG+ +Q ++E A++ +SG I+I TD+ SRGLD+ D+T V NY
Sbjct: 491 --------GISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNY 542
Query: 542 DFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQLMK 721
DFP+NI+ YVH + T + + D A ELI+IL+ A+Q VP+ L + +
Sbjct: 543 DFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAE 602
Query: 722 QHQ 730
Q++
Sbjct: 603 QYK 605
>sp|Q501J6|DDX17_MOUSE Probable ATP-dependent helicase DDX17 (DEAD-box protein 17)
Length = 650
Score = 175 bits (444), Expect = 1e-43
Identities = 101/241 (41%), Positives = 143/241 (59%), Gaps = 2/241 (0%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A +++ Q+NVG
Sbjct: 243 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGN 302
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQCSDLAFELYLK 355
L+L+A H + Q V+ +K +L++++ EI + E+K IIFV K +C DL +
Sbjct: 303 LELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMR-- 360
Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535
+ A IHGD Q ER+ L RSG I+IATDVASRGLD+ D+ VI
Sbjct: 361 --------RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVI 412
Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715
NYD+P + E+YVH A+TF + A ELI++LE+A+Q + L QL
Sbjct: 413 NYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQL 472
Query: 716 M 718
+
Sbjct: 473 V 473
>sp|P24783|DBP2_YEAST Probable ATP-dependent RNA helicase DBP2 (p68-like protein)
Length = 546
Score = 174 bits (441), Expect = 2e-43
Identities = 100/242 (41%), Positives = 144/242 (59%), Gaps = 2/242 (0%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A ++ +PIQV VG+
Sbjct: 264 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGS 323
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPED--KIIIFVARKAQCSDLAFELYLK 355
L+L+A H + Q VE V +K RL + L ++ K +IF + K C D+ YL+
Sbjct: 324 LELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNEYKTLIFASTKRMCDDIT--KYLR 381
Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535
+ A IHGD DQ+ER+ L+ R+G IM+ATDVA+RG+D+ + VI
Sbjct: 382 --------EDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVI 433
Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715
NYD P NIE+YVH A +F + + A+LI I+ +A+Q +P P+L
Sbjct: 434 NYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIP---PEL 490
Query: 716 MK 721
+K
Sbjct: 491 LK 492
>sp|P24782|DBP2_SCHPO Probable ATP-dependent RNA helicase DBP2 (p68-like protein)
Length = 550
Score = 174 bits (440), Expect = 3e-43
Identities = 102/242 (42%), Positives = 139/242 (57%), Gaps = 2/242 (0%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEADRMLDMGFE Q+ ++ +R RQTVM SATWP VQR+A ++ + IQV VG+
Sbjct: 273 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTVMFSATWPKEVQRLARDYLNDYIQVTVGS 332
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQCSDLAFELYLK 355
LDL A H ++Q VE V+ DK RL + + E+ ++K++IF K D+ L
Sbjct: 333 LDLAASHNIKQIVEVVDNADKRARLGKDIEEVLKDRDNKVLIFTGTKRVADDITRFL--- 389
Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535
R G A IHGD Q ER+ L R+G IM+ATDVASRG+D+ +T V
Sbjct: 390 RQDGW-------PALAIHGDKAQDERDWVLNEFRTGKSPIMVATDVASRGIDVKGITHVF 442
Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLPQL 715
NYDFP N E+YVH A+T+ + A EL+ IL +A Q++ L ++
Sbjct: 443 NYDFPGNTEDYVHRIGRTGRAGAKGTAYTYFTSDNAKQARELVSILSEAKQDIDPKLEEM 502
Query: 716 MK 721
+
Sbjct: 503 AR 504
>sp|P19109|RM62_DROME ATP-dependent RNA helicase P62
Length = 719
Score = 173 bits (438), Expect = 6e-43
Identities = 100/244 (40%), Positives = 145/244 (59%), Gaps = 4/244 (1%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A + N IQ+N+G+
Sbjct: 432 LVLDEADRMLDMGFEPQIRKIVSQIRPDRQTLMWSATWPKEVKQLAEDFLGNYIQINIGS 491
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEI----KPEDKIIIFVARKAQCSDLAFELY 349
L+L+A H +RQ V+ + K ++L +LS+I + KIIIFV K + +L +
Sbjct: 492 LELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRRVDNL---VR 548
Query: 350 LKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTK 529
RS G VR IHGD Q ER+ L+ RSG NI++ATDVA+RGLD+ +
Sbjct: 549 FIRSFG-------VRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAARGLDVDGIKY 601
Query: 530 VINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFLP 709
VIN+D+P+N E+Y+H +F F K + A L+ +L +A+QE+ L
Sbjct: 602 VINFDYPQNSEDYIHRIGRTGRSNTKGTSFAFFTKNNAKQAKALVDVLREANQEINPALE 661
Query: 710 QLMK 721
L +
Sbjct: 662 NLAR 665
>sp|Q6CIV2|DBP2_KLULA Probable ATP-dependent RNA helicase DBP2
Length = 554
Score = 172 bits (437), Expect = 7e-43
Identities = 100/237 (42%), Positives = 141/237 (59%), Gaps = 2/237 (0%)
Frame = +2
Query: 2 LVLDEADRMLDMGFELQVVNLIYAVRRQRQTVMTSATWPFGVQRIALTHMKNPIQVNVGT 181
LVLDEADRMLDMGFE Q+ ++ +R RQT+M SATWP V+++A ++ +PIQV +G+
Sbjct: 264 LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLASDYLHDPIQVQIGS 323
Query: 182 LDLNACHTVRQHVEYVEYHDKTQRLVEILSEIK--PEDKIIIFVARKAQCSDLAFELYLK 355
L+L+A HT+ Q VE + +K RL + L + KIIIF + K C ++ L
Sbjct: 324 LELSASHTITQIVEVLTDFEKRDRLAKHLETASQDQDSKIIIFASTKRTCDEITSYL--- 380
Query: 356 RSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLDIVDLTKVI 535
R++G A IHGD Q ER+ L RSG IM+ATDVA+RG+D+ + VI
Sbjct: 381 RTEGW-------PALAIHGDKAQNERDWVLAEFRSGRSPIMVATDVAARGIDVKGINYVI 433
Query: 536 NYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQEVPDFL 706
NYD P NIE+YVH A +F + + S A LI+I+ +A Q++P+ L
Sbjct: 434 NYDMPGNIEDYVHRIGRTGRAGSTGTAISFFTEGNKSLGAALIKIMREAKQDIPEEL 490
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,398,488
Number of Sequences: 369166
Number of extensions: 1503269
Number of successful extensions: 4506
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4168
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4275
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7473924075
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)