Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_M06
(926 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NXZ2|DDX43_HUMAN Probable ATP-dependent RNA helicase D... 137 6e-32
sp|P46942|DB10_NICSY RNA helicase-like protein DB10 124 3e-28
sp|Q92841|DDX17_HUMAN Probable ATP-dependent helicase DDX17... 123 8e-28
sp|Q501J6|DDX17_MOUSE Probable ATP-dependent helicase DDX17... 123 8e-28
sp|Q86TM3|DDX53_HUMAN Probable ATP-dependent RNA helicase D... 122 2e-27
sp|P24783|DBP2_YEAST Probable ATP-dependent RNA helicase DB... 120 4e-27
sp|Q6FLF3|DBP2_CANGA Probable ATP-dependent RNA helicase DBP2 120 4e-27
sp|P19109|RM62_DROME ATP-dependent RNA helicase P62 120 5e-27
sp|Q6CIV2|DBP2_KLULA Probable ATP-dependent RNA helicase DBP2 119 9e-27
sp|Q61656|DDX5_MOUSE Probable RNA-dependent helicase p68 (D... 116 8e-26
>sp|Q9NXZ2|DDX43_HUMAN Probable ATP-dependent RNA helicase DDX43 (DEAD-box protein 43)
(DEAD-box protein HAGE) (Helical antigen)
Length = 648
Score = 137 bits (344), Expect = 6e-32
Identities = 74/196 (37%), Positives = 115/196 (58%)
Frame = +3
Query: 6 THMKNPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKAQ 185
+++K P+ V VGTLDL A +V+Q++ +K + L + DK+I+FV+RKA
Sbjct: 440 SYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAV 499
Query: 186 CSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASR 365
L+ +L L G + +HGD +Q++RE AL+ ++G I+IATD+ASR
Sbjct: 500 ADHLSSDLIL----------GNISVESLHGDREQRDREKALENFKTGKVRILIATDLASR 549
Query: 366 GLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDA 545
GLD+ D+T V N+DFP+NIEEYVH + T + + DW A+ELI ILE A
Sbjct: 550 GLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERA 609
Query: 546 DQEVPDFLPQLMKQHQ 593
+Q +P+ L + ++ +
Sbjct: 610 NQSIPEELVSMAERFE 625
>sp|P46942|DB10_NICSY RNA helicase-like protein DB10
Length = 607
Score = 124 bits (312), Expect = 3e-28
Identities = 74/182 (40%), Positives = 104/182 (57%), Gaps = 1/182 (0%)
Frame = +3
Query: 18 NPIQVNVGTLD-LNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKAQCSD 194
N +QVN+G +D L A ++ QH+E V +K +R+ +IL +P KIIIF + K C
Sbjct: 346 NSVQVNIGNVDELVANKSITQHIEVVLPMEKQRRVEQILRSKEPGSKIIIFCSTKKMCDQ 405
Query: 195 LAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASRGLD 374
L+ L R+ G A IHGD Q ER+ L R+G +++ATDVA+RGLD
Sbjct: 406 LSRNL--TRNFG---------AAAIHGDKSQGERDYVLSQFRAGRSPVLVATDVAARGLD 454
Query: 375 IVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDADQE 554
I D+ VINYDFP IE+YVH A+TF + D +A +L+++LE A+Q
Sbjct: 455 IKDIRVVINYDFPTGIEDYVHRIGRTGRAGASGLAYTFFSDQDSKHALDLVKVLEGANQC 514
Query: 555 VP 560
VP
Sbjct: 515 VP 516
>sp|Q92841|DDX17_HUMAN Probable ATP-dependent helicase DDX17 (DEAD-box protein 17)
(RNA-dependent helicase p72) (DEAD-box protein p72)
Length = 650
Score = 123 bits (308), Expect = 8e-28
Identities = 73/192 (38%), Positives = 107/192 (55%), Gaps = 2/192 (1%)
Frame = +3
Query: 12 MKNPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQ 185
+++ Q+NVG L+L+A H + Q V+ +K +L++++ EI + E+K IIFV K +
Sbjct: 292 LRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRR 351
Query: 186 CSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASR 365
C DL + + A IHGD Q ER+ L RSG I+IATDVASR
Sbjct: 352 CDDLTRRMR----------RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 401
Query: 366 GLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDA 545
GLD+ D+ VINYD+P + E+YVH A+TF + A ELI++LE+A
Sbjct: 402 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA 461
Query: 546 DQEVPDFLPQLM 581
+Q + L QL+
Sbjct: 462 NQAINPKLMQLV 473
>sp|Q501J6|DDX17_MOUSE Probable ATP-dependent helicase DDX17 (DEAD-box protein 17)
Length = 650
Score = 123 bits (308), Expect = 8e-28
Identities = 73/192 (38%), Positives = 107/192 (55%), Gaps = 2/192 (1%)
Frame = +3
Query: 12 MKNPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQ 185
+++ Q+NVG L+L+A H + Q V+ +K +L++++ EI + E+K IIFV K +
Sbjct: 292 LRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRR 351
Query: 186 CSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASR 365
C DL + + A IHGD Q ER+ L RSG I+IATDVASR
Sbjct: 352 CDDLTRRMR----------RDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 401
Query: 366 GLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDA 545
GLD+ D+ VINYD+P + E+YVH A+TF + A ELI++LE+A
Sbjct: 402 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEA 461
Query: 546 DQEVPDFLPQLM 581
+Q + L QL+
Sbjct: 462 NQAINPKLMQLV 473
>sp|Q86TM3|DDX53_HUMAN Probable ATP-dependent RNA helicase DDX53 (DEAD-box protein 53)
(DEAD-box protein CAGE) (Cancer-associated gene protein)
Length = 631
Score = 122 bits (305), Expect = 2e-27
Identities = 67/197 (34%), Positives = 114/197 (57%)
Frame = +3
Query: 3 LTHMKNPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPEDKIIIFVARKA 182
L+++K+P+ V VG L+L A +TV+Q++ +K E + + P DK+I+FV++K
Sbjct: 419 LSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKH 478
Query: 183 QCSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVAS 362
DL+ + ++ + A +HG+ +Q ++E A++ +SG I+I TD+ S
Sbjct: 479 IADDLSSDFNIQ----------GISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVS 528
Query: 363 RGLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILED 542
RGLD+ D+T V NYDFP+NI+ YVH + T + + D A ELI+IL+
Sbjct: 529 RGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDR 588
Query: 543 ADQEVPDFLPQLMKQHQ 593
A+Q VP+ L + +Q++
Sbjct: 589 ANQSVPEDLVVMAEQYK 605
>sp|P24783|DBP2_YEAST Probable ATP-dependent RNA helicase DBP2 (p68-like protein)
Length = 546
Score = 120 bits (302), Expect = 4e-27
Identities = 72/194 (37%), Positives = 107/194 (55%), Gaps = 2/194 (1%)
Frame = +3
Query: 9 HMKNPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPED--KIIIFVARKA 182
++ +PIQV VG+L+L+A H + Q VE V +K RL + L ++ K +IF + K
Sbjct: 312 YLNDPIQVQVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNEYKTLIFASTKR 371
Query: 183 QCSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVAS 362
C D+ YL+ A IHGD DQ+ER+ L+ R+G IM+ATDVA+
Sbjct: 372 MCDDIT--KYLRED--------GWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAA 421
Query: 363 RGLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILED 542
RG+D+ + VINYD P NIE+YVH A +F + + A+LI I+ +
Sbjct: 422 RGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMRE 481
Query: 543 ADQEVPDFLPQLMK 584
A+Q +P P+L+K
Sbjct: 482 ANQNIP---PELLK 492
>sp|Q6FLF3|DBP2_CANGA Probable ATP-dependent RNA helicase DBP2
Length = 544
Score = 120 bits (302), Expect = 4e-27
Identities = 73/194 (37%), Positives = 106/194 (54%), Gaps = 2/194 (1%)
Frame = +3
Query: 9 HMKNPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKP--EDKIIIFVARKA 182
++ +PIQV +G+L+L A H + Q VE V +K RLV+ L E KI+IF + K
Sbjct: 309 YLNDPIQVQIGSLELAASHNITQLVEVVSEFEKRDRLVKHLDTASQDKESKILIFASTKR 368
Query: 183 QCSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVAS 362
C ++ YL++ A IHGD DQ+ER+ L R+G IM+ATDVA+
Sbjct: 369 TCDEITS--YLRQD--------GWPALAIHGDKDQRERDWVLNEFRTGNSPIMVATDVAA 418
Query: 363 RGLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILED 542
RG+D+ + V+NYD P NIE+YVH A +F + + S A LI I+ +
Sbjct: 419 RGIDVKGINFVVNYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEDNKSLGASLISIMRE 478
Query: 543 ADQEVPDFLPQLMK 584
A Q +P+ +LMK
Sbjct: 479 AKQNIPE---ELMK 489
>sp|P19109|RM62_DROME ATP-dependent RNA helicase P62
Length = 719
Score = 120 bits (301), Expect = 5e-27
Identities = 72/193 (37%), Positives = 108/193 (55%), Gaps = 4/193 (2%)
Frame = +3
Query: 18 NPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEI----KPEDKIIIFVARKAQ 185
N IQ+N+G+L+L+A H +RQ V+ + K ++L +LS+I + KIIIFV K +
Sbjct: 483 NYIQINIGSLELSANHNIRQVVDVCDEFSKEEKLKTLLSDIYDTSESPGKIIIFVETKRR 542
Query: 186 CSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASR 365
+L + RS G VR IHGD Q ER+ L+ RSG NI++ATDVA+R
Sbjct: 543 VDNLVRFI---RSFG-------VRCGAIHGDKSQSERDFVLREFRSGKSNILVATDVAAR 592
Query: 366 GLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDA 545
GLD+ + VIN+D+P+N E+Y+H +F F K + A L+ +L +A
Sbjct: 593 GLDVDGIKYVINFDYPQNSEDYIHRIGRTGRSNTKGTSFAFFTKNNAKQAKALVDVLREA 652
Query: 546 DQEVPDFLPQLMK 584
+QE+ L L +
Sbjct: 653 NQEINPALENLAR 665
>sp|Q6CIV2|DBP2_KLULA Probable ATP-dependent RNA helicase DBP2
Length = 554
Score = 119 bits (299), Expect = 9e-27
Identities = 72/189 (38%), Positives = 105/189 (55%), Gaps = 2/189 (1%)
Frame = +3
Query: 9 HMKNPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEIKPED--KIIIFVARKA 182
++ +PIQV +G+L+L+A HT+ Q VE + +K RL + L + KIIIF + K
Sbjct: 312 YLHDPIQVQIGSLELSASHTITQIVEVLTDFEKRDRLAKHLETASQDQDSKIIIFASTKR 371
Query: 183 QCSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVAS 362
C ++ L R++G A IHGD Q ER+ L RSG IM+ATDVA+
Sbjct: 372 TCDEITSYL---RTEGW-------PALAIHGDKAQNERDWVLAEFRSGRSPIMVATDVAA 421
Query: 363 RGLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILED 542
RG+D+ + VINYD P NIE+YVH A +F + + S A LI+I+ +
Sbjct: 422 RGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGSTGTAISFFTEGNKSLGAALIKIMRE 481
Query: 543 ADQEVPDFL 569
A Q++P+ L
Sbjct: 482 AKQDIPEEL 490
>sp|Q61656|DDX5_MOUSE Probable RNA-dependent helicase p68 (DEAD-box protein p68)
(DEAD-box protein 5) (DEAD-box RNA helicase DEAD1)
(mDEAD1)
Length = 614
Score = 116 bits (291), Expect = 8e-26
Identities = 66/193 (34%), Positives = 107/193 (55%), Gaps = 2/193 (1%)
Frame = +3
Query: 12 MKNPIQVNVGTLDLNACHTVRQHVEYVEYHDKTQRLVEILSEI--KPEDKIIIFVARKAQ 185
+K+ I +N+G L+L+A H + Q V+ +K ++L+ ++ EI + E+K I+FV K +
Sbjct: 294 LKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRR 353
Query: 186 CSDLAFELYLKRSKGLLGPKGAVRACEIHGDLDQQEREMALKMMRSGARNIMIATDVASR 365
C +L ++ + A IHGD QQER+ L + G I+IATDVASR
Sbjct: 354 CDELTRKMR----------RDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASR 403
Query: 366 GLDIVDLTKVINYDFPKNIEEYVHXXXXXXXXXXXXEAFTFMNKIDWSNAAELIRILEDA 545
GLD+ D+ VINYD+P + E+Y+H A+TF + ++LI +L +A
Sbjct: 404 GLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREA 463
Query: 546 DQEVPDFLPQLMK 584
+Q + L QL++
Sbjct: 464 NQAINPKLLQLVE 476
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,390,746
Number of Sequences: 369166
Number of extensions: 1604607
Number of successful extensions: 4701
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4540
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4667
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9510757740
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)