Planarian EST Database

DrC_00623

Cluster detail
GO Category : Not Available
Consensus Sequence :
>DrC_00623 TTCTATATTTTATTAAAACATTAAGTATTATTTTTGAAAATATGGCCTGTGATGAACTTA TTGGATGTCTTTTAACAAGTTTTGGAATTCCAATAGTACTGGTGTTATTTACTATAATAA CTCATCCTTTACGAGTCATTACACTAATTATTAGTTCAAGTTTCTGGTTGGTTTCATTTT TATTTTCATCTATTTTGTGGTATGCTGTGGTTCCATTAAAATCTAAACTTGCTTTTGGAT TAGTTTTTTCAGTGATTTTCCAAGAAGCAATACGTTTTCTATTTATTTATTGTCTTCACA AAATCGATCGAGGCATAAAGCTAATTATGTTTGATTTGAAAAGTTCCGAACCGAGTACCG ATCGCTCATTAACGAGCAATATTGACATAGCAACCACCTCTAACAACATCAATTACCATC GGGATGGCGAGGAAGGCAACAAACCGTTGATTGCTAGCGACAAAAGCACCGAGGACATTT TCAACGTGACGATGTTCGCGTATGTCGGAGGCCTCGGATTCGGCTTGATGTCGGGCTTGT TCGCCTCTCTGAACATGCTGGTCGCGCTGCGAGGCCCCGGAACGCTCGGATATTTCGGCC AATCGGCTGATTTCATCGATTTTTACGCCGCCCAAACGCTGCTCGTCGTGCTGTTCCACG TCGCGTTCCACGTGCTCATGTCCCAAGGCGTACCAGGCGAGATCCCTCGTGAAATTCGGC GCCATCCTGCTCGTTCACATGCTCTACTCGTGTTTGACGCTCGCCAACAACTCGCCTTCT CCAGCTCCAGAAATCGTGCTCGCGGTAAACGCGGTTCTCTGCTTCTCGTCGTGCTGCTGG GCG

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00623
         (843 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9VQG2|APH1_DROME  Gamma-secretase subunit Aph-1 (Preseni...    64   4e-10
sp|Q8JHE9|APH1B_BRARE  Gamma-secretase subunit Aph-1b (Anter...    44   6e-04
sp|Q96BI3|APH1A_HUMAN  Gamma-secretase subunit APH-1A (APH-1...    40   0.008
sp|Q8C7N7|APH1B_MOUSE  Gamma-secretase subunit APH-1B (APH-1...    39   0.014
sp|Q9DCZ9|APH1C_MOUSE  Putative gamma-secretase subunit APH-1C     39   0.014
sp|Q8WW43|APH1B_HUMAN  Gamma-secretase subunit APH-1B (APH-1...    39   0.014
sp|Q8BVF7|APH1A_MOUSE  Gamma-secretase subunit APH-1A (APH-1...    39   0.014
sp|Q5RDM3|APH1B_PONPY  Gamma-secretase subunit APH-1B (APH-1...    39   0.014
sp|P32832|NPL6_YEAST  Protein NPL6                                 32   1.7  
sp|P07270|PHO4_YEAST  Phosphate system positive regulatory p...    32   2.9

>sp|Q9VQG2|APH1_DROME Gamma-secretase subunit Aph-1 (Presenilin-stabilization factor)
          Length = 238

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 53/198 (26%), Positives = 75/198 (37%)
 Frame = +3

Query: 42  MACDELIGCLLTSFGIPIVLVLFTIITHPLRVITXXXXXXXXXXXXXXXXXXXYAVVPLK 221
           M   E  GC   +FG P  L +FTI   P+R+I                    YA++PLK
Sbjct: 1   MTLPEFFGCTFIAFGPPFALFVFTIANDPVRIIILIAAAFFWLLSLLISSLW-YALIPLK 59

Query: 222 SKLAFGLVFSVIFQEAIRFLFIYCLHKIDRGIKLIMFDLKSSEPSTDRSLTSNIDIATTS 401
             LAFG+VFSV FQEA R++    L   ++G+  +  D + ++     +  S +     S
Sbjct: 60  EFLAFGVVFSVCFQEAFRYIIYRILRSTEQGLHAVAEDTRVTDNKHILAYVSGLGFGIIS 119

Query: 402 NNINYHRDGEEGNKPLIASDKSTEDIFNVTMFAYVXXXXXXXXXXXXXXXNMLVALRGPG 581
                                         MFA V               N+L  + GPG
Sbjct: 120 G-----------------------------MFALV---------------NVLADMSGPG 135

Query: 582 TLGYFGQSADFIDFYAAQ 635
           T+G  G +  F    AAQ
Sbjct: 136 TMGLKGGTELFFVTSAAQ 153

>sp|Q8JHE9|APH1B_BRARE Gamma-secretase subunit Aph-1b (Anterior-pharynx-defective protein
           1b)
          Length = 258

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 29/94 (30%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
 Frame = +3

Query: 63  GCLLTSFGIPIVLVLFTIITHPLRVITXXXXXXXXXXXXXXXXXXXYAVVPLKSK----- 227
           GC   +FG  I L +FTI   PLRVI                    +  V + +K     
Sbjct: 8   GCTFIAFGPAIALFMFTIARDPLRVIFLIAGAFFWLVSLLLSSLVWFITVQISNKNSATQ 67

Query: 228 ----LAFGLVFSVIFQEAIRFLFIYCLHKIDRGI 317
               L FG+V SV+ QEA R+ +   L K + G+
Sbjct: 68  QRGLLIFGVVLSVLLQEAFRYGYYRLLKKANEGL 101

>sp|Q96BI3|APH1A_HUMAN Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha)
           (Presenilin-stabilization factor)
          Length = 265

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 29/110 (26%), Positives = 40/110 (36%), Gaps = 9/110 (8%)
 Frame = +3

Query: 42  MACDELIGCLLTSFGIPIVLVLFTIITHPLRVITXXXXXXXXXXXXXXXXXXXYAVVPLK 221
           M      GC   +FG    L L T+   PLRVI                    + +V + 
Sbjct: 1   MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60

Query: 222 SK---------LAFGLVFSVIFQEAIRFLFIYCLHKIDRGIKLIMFDLKS 344
            +         L FG   SV+ QE  RF +   L K D G+  +  D +S
Sbjct: 61  DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRS 110

>sp|Q8C7N7|APH1B_MOUSE Gamma-secretase subunit APH-1B (APH-1b) (Aph-1beta)
          Length = 257

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 29/104 (27%), Positives = 38/104 (36%), Gaps = 9/104 (8%)
 Frame = +3

Query: 42  MACDELIGCLLTSFGIPIVLVLFTIITHPLRVITXXXXXXXXXXXXXXXXXXXYAVVPLK 221
           M      GC   +FG  + L +FTI T PLRVI                    + V  + 
Sbjct: 1   MTAAVFFGCAFIAFGPALALYVFTIATDPLRVIFLIAGAFFWLVSLLLSSVFWFLVRVIT 60

Query: 222 SK---------LAFGLVFSVIFQEAIRFLFIYCLHKIDRGIKLI 326
                      L FG++ SV  QE  R  +   L K   G+K I
Sbjct: 61  DNRDGPVQNYLLIFGVLLSVCIQELFRLAYYKLLKKASEGLKSI 104

>sp|Q9DCZ9|APH1C_MOUSE Putative gamma-secretase subunit APH-1C
          Length = 258

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 9/104 (8%)
 Frame = +3

Query: 42  MACDELIGCLLTSFGIPIVLVLFTIITHPLRVITXXXXXXXXXXXXXXXXXXXYAVVPLK 221
           M      GC   +FG    L LFTI T PLRVI                    + V  + 
Sbjct: 1   MTLPVFFGCAFIAFGPAFALYLFTIATDPLRVIFLIAGAFFWLVSLLLSSMFWFLVRVIT 60

Query: 222 SK---------LAFGLVFSVIFQEAIRFLFIYCLHKIDRGIKLI 326
           +          L FG + SV  QE  R  +   L K   G+K I
Sbjct: 61  NNRDESVQNYLLIFGALLSVCIQELFRLAYYKLLKKASEGLKSI 104

>sp|Q8WW43|APH1B_HUMAN Gamma-secretase subunit APH-1B (APH-1b) (Aph-1beta)
           (Presenilin-stabilization factor-like)
          Length = 257

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 31/104 (29%), Positives = 40/104 (38%), Gaps = 9/104 (8%)
 Frame = +3

Query: 42  MACDELIGCLLTSFGIPIVLVLFTIITHPLRVITXXXXXXXXXXXXXXXXXXXY-AVVPL 218
           M      GC   +FG  + L +FTI T PLR+I                    + A V +
Sbjct: 1   MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60

Query: 219 KSK--------LAFGLVFSVIFQEAIRFLFIYCLHKIDRGIKLI 326
            +K        L FG   SV  QE  RF +   L K   G+K I
Sbjct: 61  DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSI 104

>sp|Q8BVF7|APH1A_MOUSE Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha)
          Length = 265

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 29/110 (26%), Positives = 40/110 (36%), Gaps = 9/110 (8%)
 Frame = +3

Query: 42  MACDELIGCLLTSFGIPIVLVLFTIITHPLRVITXXXXXXXXXXXXXXXXXXXYAVVPLK 221
           M      GC   +FG    L L T+   PLRVI                    + +V + 
Sbjct: 1   MGAAVFFGCTFVAFGPAFSLFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60

Query: 222 SK---------LAFGLVFSVIFQEAIRFLFIYCLHKIDRGIKLIMFDLKS 344
            +         L FG   SV+ QE  RF +   L K D G+  +  D +S
Sbjct: 61  DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRS 110

>sp|Q5RDM3|APH1B_PONPY Gamma-secretase subunit APH-1B (APH-1b) (Aph-1beta)
          Length = 257

 Score = 39.3 bits (90), Expect = 0.014
 Identities = 31/104 (29%), Positives = 40/104 (38%), Gaps = 9/104 (8%)
 Frame = +3

Query: 42  MACDELIGCLLTSFGIPIVLVLFTIITHPLRVITXXXXXXXXXXXXXXXXXXXY-AVVPL 218
           M      GC   +FG  + L +FTI T PLR+I                    + A V +
Sbjct: 1   MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60

Query: 219 KSK--------LAFGLVFSVIFQEAIRFLFIYCLHKIDRGIKLI 326
            +K        L FG   SV  QE  RF +   L K   G+K I
Sbjct: 61  DNKDGPTQKYLLIFGTFVSVYIQEMFRFAYYRLLKKASEGLKSI 104

>sp|P32832|NPL6_YEAST Protein NPL6
          Length = 435

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 23/80 (28%), Positives = 37/80 (46%)
 Frame = -2

Query: 779 EGELLASVKHE*SM*TSRMAPNFTRDLAWYALGHEHVERDVEQHDEQRLGGVKIDEISRL 600
           EG L + V+HE    ++   PN+  D     +       D +  +E+   GV  +EIS  
Sbjct: 5   EGGLASEVEHEKRSRSTSNRPNYAIDTEDLDIDENDENEDDDYREEEANEGVNEEEISDE 64

Query: 599 AEISERSGASQRDQHVQRGE 540
            E   +SG ++R +HV   E
Sbjct: 65  EEQINKSGRNKR-RHVDEEE 83

>sp|P07270|PHO4_YEAST Phosphate system positive regulatory protein PHO4
          Length = 312

 Score = 31.6 bits (70), Expect = 2.9
 Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
 Frame = -3

Query: 622 KSMKSADWPKYPSVPGPRSATSMFR--EANKPDIKPNPRPPTYANIV 488
           KS  S    K    PGP SATS+F   ++  P  KP P+P  Y  ++
Sbjct: 148 KSNSSPYLNKRRGKPGPDSATSLFELPDSVIPTPKPKPKPKQYPKVI 194

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,413,261
Number of Sequences: 369166
Number of extensions: 1717109
Number of successful extensions: 5393
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5124
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5383
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8245425915
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00623

Planaria EST Database

DrC_00623

BLASTX 2.2.13 [Nov-27-2005]

Cluster detail