Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00590 (1203 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q02645|HTS_DROME Hu-li tai shao protein (Adducin-like pr... 124 4e-28 sp|Q05764|ADDB_RAT Beta-adducin (Erythrocyte adducin beta s... 98 4e-20 sp|Q9QYB8|ADDB_MOUSE Beta-adducin (Erythrocyte adducin beta... 97 7e-20 sp|P35612|ADDB_HUMAN Beta-adducin (Erythrocyte adducin beta... 93 2e-18 sp|Q9U9K0|ADD1_CAEEL Adducin-related protein 1 90 1e-17 sp|Q9QYC0|ADDA_MOUSE Alpha-adducin (Erythrocyte adducin alp... 80 9e-15 sp|Q63028|ADDA_RAT Alpha-adducin (Erythrocyte adducin alpha... 80 9e-15 sp|P35611|ADDA_HUMAN Alpha-adducin (Erythrocyte adducin alp... 79 3e-14 sp|Q9UEY8|ADDG_HUMAN Gamma-adducin (Adducin-like protein 70) 73 1e-12 sp|Q9QYB5|ADDG_MOUSE Gamma-adducin (Adducin-like protein 70) 70 1e-11
>sp|Q02645|HTS_DROME Hu-li tai shao protein (Adducin-like protein) Length = 1156 Score = 124 bits (312), Expect = 4e-28 Identities = 80/246 (32%), Positives = 127/246 (51%), Gaps = 16/246 (6%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSSTS 182 E+LMR LD AG+RTGY+Y+H L+ D + +D +PP+ +S Sbjct: 376 EALMRMLDNAGYRTGYIYRHPLIKSDPPKPKNDVE------------------LPPAVSS 417 Query: 183 FATRTEQ-----------GDEAVKQKQPQTQWLLHTPNDYVREEITENGT---RKVVSWR 320 E+ GD +++ +++WL ++PN Y + E+ E GT +K+ W Sbjct: 418 LGYLLEEEELFRQGIWKKGD--IRKGGDRSRWL-NSPNVYQKVEVLETGTPDPKKITKWV 474 Query: 321 PVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNV 500 + + T +E P QF P G + E K QQ +K D+ SAG QS +L V Sbjct: 475 AEGSPTHSTPVRIE---DPLQFVPAGTNpreFKRVQQLIKDNRRADKISAGPQSHILEGV 531 Query: 501 --DQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLK 674 D+ S + ++ VV++GA S+GII + +H+ +VY++ ++ NPFD VTDD+L Sbjct: 532 TWDEASRLKDATVSQAGDHVVMMGAASKGIIQRGFQHNATVYKAPYAKNPFDNVTDDELN 591 Query: 675 QYKRKV 692 +YKR V Sbjct: 592 EYKRTV 597
>sp|Q05764|ADDB_RAT Beta-adducin (Erythrocyte adducin beta subunit) (Adducin 63) Length = 725 Score = 98.2 bits (243), Expect = 4e-20 Identities = 82/279 (29%), Positives = 133/279 (47%), Gaps = 14/279 (5%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSSTS 182 E+LMR LD G+RTGY Y+H V K + + IP + T+ Sbjct: 366 EALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVE-------------------IPATVTA 406 Query: 183 FATRTEQG-------DEAVKQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRP----VS 329 F E G A KQ++ +T+WL +TPN Y+R + + R + S RP + Sbjct: 407 FVFE-EDGVPVPALRQHAQKQQKEKTRWL-NTPNTYLRVNVADEVQRNMGSPRPKTTWMK 464 Query: 330 ADS--RQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVD 503 AD + +SG+ +PNQF P D E+ + K++ + +D SAG QS++L +V Sbjct: 465 ADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLDMRNKIREQNRQDIKSAGPQSQLLASV- 523 Query: 504 QTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYK 683 +E P ES S+G D + + +V PNPF ++TD +L++YK Sbjct: 524 -IAEKSRSPSTES-------QLASKGDADTKDELEETV------PNPFSQLTDQELEEYK 569 Query: 684 RKVLGLPPDEIETSKQEVSFTEP-SVTDTNISSPVDKPT 797 ++V ++ + +++ + EP S + +SPV PT Sbjct: 570 KEVERKKLEQEQEGEKDAATEEPGSPVKSTPASPVQSPT 608
>sp|Q9QYB8|ADDB_MOUSE Beta-adducin (Erythrocyte adducin beta subunit) (Add97) Length = 725 Score = 97.4 bits (241), Expect = 7e-20 Identities = 80/279 (28%), Positives = 135/279 (48%), Gaps = 14/279 (5%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSSTS 182 E+LMR LD G+RTGY Y+H V K + + IP + T+ Sbjct: 366 EALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVE-------------------IPATVTA 406 Query: 183 FATRTEQG-------DEAVKQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRP----VS 329 F E G A KQ++ +T+WL +TPN Y+R + + R + S RP + Sbjct: 407 FVFE-EDGVPVPALRQHAQKQQKEKTRWL-NTPNTYLRVNVADEVQRNMGSPRPKTTWMK 464 Query: 330 ADS--RQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVD 503 AD + +SG+ +PNQF P D E+ + K++ + +D SAG QS++L +V Sbjct: 465 ADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLDMRNKIREQNRQDIKSAGPQSQLLASV- 523 Query: 504 QTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYK 683 +E P ES +S+G D + + +V PNPF ++TD +L++YK Sbjct: 524 -IAEKSRSPSTES-------QLMSKGDADTKDESEETV------PNPFSQLTDQELEEYK 569 Query: 684 RKVLGLPPDEIETSKQEVSFTEP-SVTDTNISSPVDKPT 797 ++V ++ + +++++ +P S + +SPV P+ Sbjct: 570 KEVERKKLEQEQEGEKDIATEKPGSPVKSTPASPVQSPS 608
>sp|P35612|ADDB_HUMAN Beta-adducin (Erythrocyte adducin beta subunit) Length = 726 Score = 92.8 bits (229), Expect = 2e-18 Identities = 82/276 (29%), Positives = 128/276 (46%), Gaps = 16/276 (5%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSSTS 182 E+LMR LD G+RTGY Y+H V K + + IP + T+ Sbjct: 366 EALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVE-------------------IPATVTA 406 Query: 183 FATRTEQG------DEAVKQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRP----VSA 332 F + A KQ++ +T+WL +TPN Y+R + + R + S RP + A Sbjct: 407 FVFEEDGAPVPALRQHAQKQQKEKTRWL-NTPNTYLRVNVADEVQRSMGSPRPKTTWMKA 465 Query: 333 DS--RQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQ 506 D + +SG+ +PNQF P D E+ + K++ + +D SAG QS++L +V Sbjct: 466 DEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASV-- 523 Query: 507 TSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYK- 683 +E P ES +S+G D + + +V PNPF ++TD +L++YK Sbjct: 524 IAEKSRSPSTES-------QLMSKGDEDTKDDSEETV------PNPFSQLTDQELEEYKK 570 Query: 684 ---RKVLGLPPDEIETSKQEVSFTEPSVTDTNISSP 782 RK L L E ET+ +E S + + SP Sbjct: 571 EVERKKLEL-DGEKETAPEEPGSPAKSAPASPVQSP 605
>sp|Q9U9K0|ADD1_CAEEL Adducin-related protein 1 Length = 732 Score = 89.7 bits (221), Expect = 1e-17 Identities = 67/246 (27%), Positives = 114/246 (46%), Gaps = 20/246 (8%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSSTS 182 ES MR LD A +TG++Y+ + + +PP++++ Sbjct: 353 ESWMRVLDHANFQTGHVYRQPQL-------------RPKSAMSTSMVNNNDVAVPPTTSA 399 Query: 183 FATRTEQGDEAV--------KQKQPQTQWLLHTPNDYVREEITENGT---RKVVSW-RPV 326 + E E+V +++Q + +W+ ++PN Y + E E G +K+ W V Sbjct: 400 YGQIDETNLESVSAHRLALLRKEQERVRWM-NSPNAYQKVEFLEYGADNPKKITKWVHDV 458 Query: 327 SADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQ 506 + S SG +S +QF+P + E K +Q+ +K SAG QS++L +V Sbjct: 459 NVPS--ASGTPVKISSVHQFSPASSNPKEFKEKQKAIKENNRLGTLSAGPQSQILDSVTY 516 Query: 507 TS-------EVDGVPDEESVG-RVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTD 662 + DG + S R +L+G S+GIID++ +H VY ++PNPF TD Sbjct: 517 EDIALLIKPDNDGTVGQSSTADRAILIGTASKGIIDRQFQHHAQVYHQIYAPNPFSVETD 576 Query: 663 DDLKQY 680 D+K+Y Sbjct: 577 ADIKKY 582
>sp|Q9QYC0|ADDA_MOUSE Alpha-adducin (Erythrocyte adducin alpha subunit) Length = 735 Score = 80.5 bits (197), Expect = 9e-15 Identities = 79/275 (28%), Positives = 128/275 (46%), Gaps = 14/275 (5%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSST- 179 E+LMR LD G+RTGY Y++ + +R ++ D +P S T Sbjct: 378 EALMRMLDNLGYRTGYPYRYPALR-ERSKKYSDVE------------------VPASVTG 418 Query: 180 -SFATRTEQGD------EAVKQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRPVSADS 338 SFA+ + G KQ++ +T+WL D EE +NG+ + D Sbjct: 419 HSFASDGDSGTCSPLRHSFQKQQREKTRWLHSGRGDDASEE-GQNGSSPKSKTKWTKEDG 477 Query: 339 RQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEV 518 +TS T PN F P + E++ + K++ + +D +AG QS+VL Sbjct: 478 HRTS----TSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLC-------- 525 Query: 519 DGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVLG 698 GV + S+ + LV A S+ II+K ++ P V S PNPF+ +TD +L++Y+R+V Sbjct: 526 -GVMMDRSLVQGELVTA-SKAIIEKEYQ--PHVIVSTTGPNPFNTLTDRELEEYRREVER 581 Query: 699 LPP------DEIETSKQEVSFTEPSVTDTNISSPV 785 DE K++ + +V +T S+PV Sbjct: 582 KQKGSEENLDETREQKEKSPPDQSAVPNTPPSTPV 616
>sp|Q63028|ADDA_RAT Alpha-adducin (Erythrocyte adducin alpha subunit) Length = 735 Score = 80.5 bits (197), Expect = 9e-15 Identities = 79/275 (28%), Positives = 128/275 (46%), Gaps = 14/275 (5%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSST- 179 E+LMR LD G+RTGY Y++ + +R ++ D +P S T Sbjct: 378 EALMRMLDNLGYRTGYPYRYPALR-ERSKKYSDVE------------------VPASVTG 418 Query: 180 -SFATRTEQGD------EAVKQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRPVSADS 338 SFA+ + G KQ++ +T+WL D EE +NG+ + D Sbjct: 419 HSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDDASEE-GQNGSSPKSKTKWTKEDG 477 Query: 339 RQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEV 518 +TS T PN F P + E++ + K++ + +D +AG QS+VL Sbjct: 478 HRTS----TSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLC-------- 525 Query: 519 DGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVLG 698 GV + S+ + LV A S+ II+K ++ P V S PNPF+ +TD +L++Y+R+V Sbjct: 526 -GVMMDRSLVQGELVTA-SKAIIEKEYQ--PHVIVSTTGPNPFNTLTDRELEEYRREVER 581 Query: 699 LPP------DEIETSKQEVSFTEPSVTDTNISSPV 785 DE K++ + +V +T S+PV Sbjct: 582 KQKGSEENLDETREQKEKSPPDQSAVPNTPPSTPV 616
>sp|P35611|ADDA_HUMAN Alpha-adducin (Erythrocyte adducin alpha subunit) Length = 737 Score = 78.6 bits (192), Expect = 3e-14 Identities = 75/276 (27%), Positives = 126/276 (45%), Gaps = 15/276 (5%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSSTS 182 E+LMR LD G+RTGY Y++ + ++ ++ D +P S T Sbjct: 378 EALMRMLDNLGYRTGYPYRYPALR-EKSKKYSDVE------------------VPASVTG 418 Query: 183 FATRTEQGDEAV---------KQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRPVSAD 335 ++ ++ GD KQ++ +T+WL D EE +NG+ + D Sbjct: 419 YSFASD-GDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEE-GQNGSSPKSKTKWTKED 476 Query: 336 SRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSE 515 +TS T PN F P + E++ + K++ + +D +AG QS+VL Sbjct: 477 GHRTS----TSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLC------- 525 Query: 516 VDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVL 695 GV + S+ + LV A S+ II+K ++ P V S PNPF +TD +L++Y+R+V Sbjct: 526 --GVVMDRSLVQGELVTA-SKAIIEKEYQ--PHVIVSTTGPNPFTTLTDRELEEYRREVE 580 Query: 696 GLPP------DEIETSKQEVSFTEPSVTDTNISSPV 785 DE K++ +P+V S+P+ Sbjct: 581 RKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 616
>sp|Q9UEY8|ADDG_HUMAN Gamma-adducin (Adducin-like protein 70) Length = 706 Score = 73.2 bits (178), Expect = 1e-12 Identities = 68/278 (24%), Positives = 121/278 (43%), Gaps = 14/278 (5%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSSTS 182 E LMR LD G+RTGY Y+H L+ R++ H + IP + T+ Sbjct: 372 EGLMRTLDNLGYRTGYAYRHPLI---REKPRHKSDVE----------------IPATVTA 412 Query: 183 FATRTEQGD------EAVKQKQPQTQWLLHTPNDYVREEITE---NGT---RKVVSWRPV 326 F+ + A +Q++ +T+WL ++PN Y++ + E NG R ++W Sbjct: 413 FSFEDDTVPLSPLKYMAQRQQREKTRWL-NSPNTYMKVNVPEESRNGETSPRTKITWMKA 471 Query: 327 SADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRN--V 500 S+ + G PNQF P + +E+ ++ K++ + D +AG QS++L V Sbjct: 472 EDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVV 531 Query: 501 DQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQY 680 D+ D++ H P PNPF +T+ +L++Y Sbjct: 532 DKPPSTMQFEDDD---------------------HGPPA-----PPNPFSHLTEGELEEY 565 Query: 681 KRKVLGLPPDEIETSKQEVSFTEPSVTDTNISSPVDKP 794 KR + +E ++QE+ ++ + + + I S P Sbjct: 566 KR-TIERKQQGLEDAEQEL-LSDDASSVSQIQSQTQSP 601
>sp|Q9QYB5|ADDG_MOUSE Gamma-adducin (Adducin-like protein 70) Length = 706 Score = 70.1 bits (170), Expect = 1e-11 Identities = 72/280 (25%), Positives = 117/280 (41%), Gaps = 16/280 (5%) Frame = +3 Query: 3 ESLMRALDAAGHRTGYLYKHALVMVDRKRRLHDQHQQXXXXXXXXXXXXXXXXIPPSSTS 182 E LMR+LD G+RTGY Y+H LV R++ H + IP + T+ Sbjct: 372 EGLMRSLDNLGYRTGYAYRHPLV---REKPRHKSDVE----------------IPATVTA 412 Query: 183 FATRTEQGD------EAVKQKQPQTQWLLHTPNDYVREEITE---NGT---RKVVSWRPV 326 F+ + A +Q++ +T+WL ++PN Y++ + E NG R ++W Sbjct: 413 FSFEDDSAPLSPLKFMAQRQQREKTRWL-NSPNTYMKVNVPEESRNGETSPRTKITWMKA 471 Query: 327 SADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQ 506 S+ +SG PNQF P + E+ ++ K++ + D +AG QS++L + Sbjct: 472 EDSSKVSSGTPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGPQSQLLAGI-- 529 Query: 507 TSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQY-- 680 VD P S D + P+ PNPF + + +L++Y Sbjct: 530 --VVDKPP--------------STMQFDDDDQGPPA------PPNPFSHLLEGELEEYTK 567 Query: 681 --KRKVLGLPPDEIETSKQEVSFTEPSVTDTNISSPVDKP 794 +RK GL D+ E S + SP P Sbjct: 568 TIERKQQGL--DDAEQGSLSDDAASVSQIQSQTQSPQSVP 605
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 113,693,399 Number of Sequences: 369166 Number of extensions: 2001366 Number of successful extensions: 5969 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5718 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5948 length of database: 68,354,980 effective HSP length: 113 effective length of database: 47,479,925 effective search space used: 13626738475 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)