Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_A14
(771 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q02645|HTS_DROME Hu-li tai shao protein (Adducin-like pr... 107 5e-23
sp|Q9U9K0|ADD1_CAEEL Adducin-related protein 1 89 1e-17
sp|Q05764|ADDB_RAT Beta-adducin (Erythrocyte adducin beta s... 85 2e-16
sp|Q9QYB8|ADDB_MOUSE Beta-adducin (Erythrocyte adducin beta... 84 4e-16
sp|P35612|ADDB_HUMAN Beta-adducin (Erythrocyte adducin beta... 79 1e-14
sp|Q9QYC0|ADDA_MOUSE Alpha-adducin (Erythrocyte adducin alp... 73 1e-12
sp|Q63028|ADDA_RAT Alpha-adducin (Erythrocyte adducin alpha... 73 1e-12
sp|P35611|ADDA_HUMAN Alpha-adducin (Erythrocyte adducin alp... 72 2e-12
sp|Q9UEY8|ADDG_HUMAN Gamma-adducin (Adducin-like protein 70) 60 5e-09
sp|Q9QYB5|ADDG_MOUSE Gamma-adducin (Adducin-like protein 70) 57 7e-08
>sp|Q02645|HTS_DROME Hu-li tai shao protein (Adducin-like protein)
Length = 1156
Score = 107 bits (266), Expect = 5e-23
Identities = 66/196 (33%), Positives = 106/196 (54%), Gaps = 16/196 (8%)
Frame = +1
Query: 16 DVEIPPSSTSFATRTEQ-----------GDEAVKQKQPQTQWLLHTPNDYVREEITENGT 162
DVE+PP+ +S E+ GD +++ +++WL ++PN Y + E+ E GT
Sbjct: 408 DVELPPAVSSLGYLLEEEELFRQGIWKKGD--IRKGGDRSRWL-NSPNVYQKVEVLETGT 464
Query: 163 ---RKVVSWRPVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSA 333
+K+ W + + T +E P QF P G + E K QQ +K D+ SA
Sbjct: 465 PDPKKITKWVAEGSPTHSTPVRIE---DPLQFVPAGTNpreFKRVQQLIKDNRRADKISA 521
Query: 334 GHQSRVLRNV--DQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNP 507
G QS +L V D+ S + ++ VV++GA S+GII + +H+ +VY++ ++ NP
Sbjct: 522 GPQSHILEGVTWDEASRLKDATVSQAGDHVVMMGAASKGIIQRGFQHNATVYKAPYAKNP 581
Query: 508 FDRVTDDDLKQYKRKV 555
FD VTDD+L +YKR V
Sbjct: 582 FDNVTDDELNEYKRTV 597
>sp|Q9U9K0|ADD1_CAEEL Adducin-related protein 1
Length = 732
Score = 89.4 bits (220), Expect = 1e-17
Identities = 59/198 (29%), Positives = 101/198 (51%), Gaps = 20/198 (10%)
Frame = +1
Query: 10 DEDVEIPPSSTSFATRTEQGDEAV--------KQKQPQTQWLLHTPNDYVREEITENGT- 162
+ DV +PP+++++ E E+V +++Q + +W+ ++PN Y + E E G
Sbjct: 388 NNDVAVPPTTSAYGQIDETNLESVSAHRLALLRKEQERVRWM-NSPNAYQKVEFLEYGAD 446
Query: 163 --RKVVSW-RPVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSA 333
+K+ W V+ S SG +S +QF+P + E K +Q+ +K SA
Sbjct: 447 NPKKITKWVHDVNVPS--ASGTPVKISSVHQFSPASSNPKEFKEKQKAIKENNRLGTLSA 504
Query: 334 GHQSRVLRNVDQTS-------EVDGVPDEESVG-RVVLVGAVSRGIIDKRHRHDPSVYQS 489
G QS++L +V + DG + S R +L+G S+GIID++ +H VY
Sbjct: 505 GPQSQILDSVTYEDIALLIKPDNDGTVGQSSTADRAILIGTASKGIIDRQFQHHAQVYHQ 564
Query: 490 CFSPNPFDRVTDDDLKQY 543
++PNPF TD D+K+Y
Sbjct: 565 IYAPNPFSVETDADIKKY 582
>sp|Q05764|ADDB_RAT Beta-adducin (Erythrocyte adducin beta subunit) (Adducin 63)
Length = 725
Score = 84.7 bits (208), Expect = 2e-16
Identities = 69/229 (30%), Positives = 116/229 (50%), Gaps = 14/229 (6%)
Frame = +1
Query: 16 DVEIPPSSTSFATRTEQG-------DEAVKQKQPQTQWLLHTPNDYVREEITENGTRKVV 174
+VEIP + T+F E G A KQ++ +T+WL +TPN Y+R + + R +
Sbjct: 397 EVEIPATVTAFVFE-EDGVPVPALRQHAQKQQKEKTRWL-NTPNTYLRVNVADEVQRNMG 454
Query: 175 SWRP----VSADS--RQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAG 336
S RP + AD + +SG+ +PNQF P D E+ + K++ + +D SAG
Sbjct: 455 SPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLDMRNKIREQNRQDIKSAG 514
Query: 337 HQSRVLRNVDQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDR 516
QS++L +V +E P ES S+G D + + +V PNPF +
Sbjct: 515 PQSQLLASV--IAEKSRSPSTES-------QLASKGDADTKDELEETV------PNPFSQ 559
Query: 517 VTDDDLKQYKRKVLGLPPDEIETSKQEVSFTEP-SVTDTNISSPVDKPT 660
+TD +L++YK++V ++ + +++ + EP S + +SPV PT
Sbjct: 560 LTDQELEEYKKEVERKKLEQEQEGEKDAATEEPGSPVKSTPASPVQSPT 608
>sp|Q9QYB8|ADDB_MOUSE Beta-adducin (Erythrocyte adducin beta subunit) (Add97)
Length = 725
Score = 84.0 bits (206), Expect = 4e-16
Identities = 67/229 (29%), Positives = 118/229 (51%), Gaps = 14/229 (6%)
Frame = +1
Query: 16 DVEIPPSSTSFATRTEQG-------DEAVKQKQPQTQWLLHTPNDYVREEITENGTRKVV 174
+VEIP + T+F E G A KQ++ +T+WL +TPN Y+R + + R +
Sbjct: 397 EVEIPATVTAFVFE-EDGVPVPALRQHAQKQQKEKTRWL-NTPNTYLRVNVADEVQRNMG 454
Query: 175 SWRP----VSADS--RQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAG 336
S RP + AD + +SG+ +PNQF P D E+ + K++ + +D SAG
Sbjct: 455 SPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLDMRNKIREQNRQDIKSAG 514
Query: 337 HQSRVLRNVDQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDR 516
QS++L +V +E P ES +S+G D + + +V PNPF +
Sbjct: 515 PQSQLLASV--IAEKSRSPSTES-------QLMSKGDADTKDESEETV------PNPFSQ 559
Query: 517 VTDDDLKQYKRKVLGLPPDEIETSKQEVSFTEP-SVTDTNISSPVDKPT 660
+TD +L++YK++V ++ + +++++ +P S + +SPV P+
Sbjct: 560 LTDQELEEYKKEVERKKLEQEQEGEKDIATEKPGSPVKSTPASPVQSPS 608
>sp|P35612|ADDB_HUMAN Beta-adducin (Erythrocyte adducin beta subunit)
Length = 726
Score = 79.3 bits (194), Expect = 1e-14
Identities = 69/226 (30%), Positives = 111/226 (49%), Gaps = 16/226 (7%)
Frame = +1
Query: 16 DVEIPPSSTSFATRTEQG------DEAVKQKQPQTQWLLHTPNDYVREEITENGTRKVVS 177
+VEIP + T+F + A KQ++ +T+WL +TPN Y+R + + R + S
Sbjct: 397 EVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWL-NTPNTYLRVNVADEVQRSMGS 455
Query: 178 WRP----VSADS--RQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGH 339
RP + AD + +SG+ +PNQF P D E+ + K++ + +D SAG
Sbjct: 456 PRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGP 515
Query: 340 QSRVLRNVDQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRV 519
QS++L +V +E P ES +S+G D + + +V PNPF ++
Sbjct: 516 QSQLLASV--IAEKSRSPSTES-------QLMSKGDEDTKDDSEETV------PNPFSQL 560
Query: 520 TDDDLKQYK----RKVLGLPPDEIETSKQEVSFTEPSVTDTNISSP 645
TD +L++YK RK L L E ET+ +E S + + SP
Sbjct: 561 TDQELEEYKKEVERKKLEL-DGEKETAPEEPGSPAKSAPASPVQSP 605
>sp|Q9QYC0|ADDA_MOUSE Alpha-adducin (Erythrocyte adducin alpha subunit)
Length = 735
Score = 72.8 bits (177), Expect = 1e-12
Identities = 68/225 (30%), Positives = 109/225 (48%), Gaps = 14/225 (6%)
Frame = +1
Query: 16 DVEIPPSST--SFATRTEQGD------EAVKQKQPQTQWLLHTPNDYVREEITENGTRKV 171
DVE+P S T SFA+ + G KQ++ +T+WL D EE +NG+
Sbjct: 409 DVEVPASVTGHSFASDGDSGTCSPLRHSFQKQQREKTRWLHSGRGDDASEE-GQNGSSPK 467
Query: 172 VSWRPVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRV 351
+ D +TS T PN F P + E++ + K++ + +D +AG QS+V
Sbjct: 468 SKTKWTKEDGHRTS----TSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQV 523
Query: 352 LRNVDQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDD 531
L GV + S+ + LV A S+ II+K ++ P V S PNPF+ +TD +
Sbjct: 524 LC---------GVMMDRSLVQGELVTA-SKAIIEKEYQ--PHVIVSTTGPNPFNTLTDRE 571
Query: 532 LKQYKRKVLGLPP------DEIETSKQEVSFTEPSVTDTNISSPV 648
L++Y+R+V DE K++ + +V +T S+PV
Sbjct: 572 LEEYRREVERKQKGSEENLDETREQKEKSPPDQSAVPNTPPSTPV 616
>sp|Q63028|ADDA_RAT Alpha-adducin (Erythrocyte adducin alpha subunit)
Length = 735
Score = 72.8 bits (177), Expect = 1e-12
Identities = 68/225 (30%), Positives = 109/225 (48%), Gaps = 14/225 (6%)
Frame = +1
Query: 16 DVEIPPSST--SFATRTEQGD------EAVKQKQPQTQWLLHTPNDYVREEITENGTRKV 171
DVE+P S T SFA+ + G KQ++ +T+WL D EE +NG+
Sbjct: 409 DVEVPASVTGHSFASDGDSGTCSPLRHSFQKQQREKTRWLNSGRGDDASEE-GQNGSSPK 467
Query: 172 VSWRPVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRV 351
+ D +TS T PN F P + E++ + K++ + +D +AG QS+V
Sbjct: 468 SKTKWTKEDGHRTS----TSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQV 523
Query: 352 LRNVDQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDD 531
L GV + S+ + LV A S+ II+K ++ P V S PNPF+ +TD +
Sbjct: 524 LC---------GVMMDRSLVQGELVTA-SKAIIEKEYQ--PHVIVSTTGPNPFNTLTDRE 571
Query: 532 LKQYKRKVLGLPP------DEIETSKQEVSFTEPSVTDTNISSPV 648
L++Y+R+V DE K++ + +V +T S+PV
Sbjct: 572 LEEYRREVERKQKGSEENLDETREQKEKSPPDQSAVPNTPPSTPV 616
>sp|P35611|ADDA_HUMAN Alpha-adducin (Erythrocyte adducin alpha subunit)
Length = 737
Score = 72.0 bits (175), Expect = 2e-12
Identities = 65/226 (28%), Positives = 107/226 (47%), Gaps = 15/226 (6%)
Frame = +1
Query: 16 DVEIPPSSTSFATRTEQGDEAV---------KQKQPQTQWLLHTPNDYVREEITENGTRK 168
DVE+P S T ++ ++ GD KQ++ +T+WL D EE +NG+
Sbjct: 409 DVEVPASVTGYSFASD-GDSGTCSPLRHSFQKQQREKTRWLNSGRGDEASEE-GQNGSSP 466
Query: 169 VVSWRPVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSR 348
+ D +TS T PN F P + E++ + K++ + +D +AG QS+
Sbjct: 467 KSKTKWTKEDGHRTS----TSAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQ 522
Query: 349 VLRNVDQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDD 528
VL GV + S+ + LV A S+ II+K ++ P V S PNPF +TD
Sbjct: 523 VLC---------GVVMDRSLVQGELVTA-SKAIIEKEYQ--PHVIVSTTGPNPFTTLTDR 570
Query: 529 DLKQYKRKVLGLPP------DEIETSKQEVSFTEPSVTDTNISSPV 648
+L++Y+R+V DE K++ +P+V S+P+
Sbjct: 571 ELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVPHPPPSTPI 616
>sp|Q9UEY8|ADDG_HUMAN Gamma-adducin (Adducin-like protein 70)
Length = 706
Score = 60.5 bits (145), Expect = 5e-09
Identities = 55/228 (24%), Positives = 102/228 (44%), Gaps = 14/228 (6%)
Frame = +1
Query: 16 DVEIPPSSTSFATRTEQGD------EAVKQKQPQTQWLLHTPNDYVREEITE---NGT-- 162
DVEIP + T+F+ + A +Q++ +T+WL ++PN Y++ + E NG
Sbjct: 403 DVEIPATVTAFSFEDDTVPLSPLKYMAQRQQREKTRWL-NSPNTYMKVNVPEESRNGETS 461
Query: 163 -RKVVSWRPVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGH 339
R ++W S+ + G PNQF P + +E+ ++ K++ + D +AG
Sbjct: 462 PRTKITWMKAEDSSKVSGGTPIKIEDPNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGP 521
Query: 340 QSRVLRN--VDQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFD 513
QS++L VD+ D++ H P PNPF
Sbjct: 522 QSQLLAGIVVDKPPSTMQFEDDD---------------------HGPPA-----PPNPFS 555
Query: 514 RVTDDDLKQYKRKVLGLPPDEIETSKQEVSFTEPSVTDTNISSPVDKP 657
+T+ +L++YKR + +E ++QE+ ++ + + + I S P
Sbjct: 556 HLTEGELEEYKR-TIERKQQGLEDAEQEL-LSDDASSVSQIQSQTQSP 601
>sp|Q9QYB5|ADDG_MOUSE Gamma-adducin (Adducin-like protein 70)
Length = 706
Score = 56.6 bits (135), Expect = 7e-08
Identities = 58/230 (25%), Positives = 97/230 (42%), Gaps = 16/230 (6%)
Frame = +1
Query: 16 DVEIPPSSTSFATRTEQGD------EAVKQKQPQTQWLLHTPNDYVREEITE---NGT-- 162
DVEIP + T+F+ + A +Q++ +T+WL ++PN Y++ + E NG
Sbjct: 403 DVEIPATVTAFSFEDDSAPLSPLKFMAQRQQREKTRWL-NSPNTYMKVNVPEESRNGETS 461
Query: 163 -RKVVSWRPVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGH 339
R ++W S+ +SG PNQF P + E+ ++ K++ + D +AG
Sbjct: 462 PRTKITWMKAEDSSKVSSGTPIKIEDPNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGP 521
Query: 340 QSRVLRNVDQTSEVDGVPDEESVGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRV 519
QS++L + VD P S D + P+ PNPF +
Sbjct: 522 QSQLLAGI----VVDKPP--------------STMQFDDDDQGPPA------PPNPFSHL 557
Query: 520 TDDDLKQY----KRKVLGLPPDEIETSKQEVSFTEPSVTDTNISSPVDKP 657
+ +L++Y +RK GL D+ E S + SP P
Sbjct: 558 LEGELEEYTKTIERKQQGL--DDAEQGSLSDDAASVSQIQSQTQSPQSVP 605
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.309 0.127 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,054,256
Number of Sequences: 369166
Number of extensions: 1396390
Number of successful extensions: 3386
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3272
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3376
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7163732800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)