Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_P12
(833 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q02645|HTS_DROME Hu-li tai shao protein (Adducin-like pr... 102 2e-21
sp|Q9U9K0|ADD1_CAEEL Adducin-related protein 1 84 4e-16
sp|Q05764|ADDB_RAT Beta-adducin (Erythrocyte adducin beta s... 80 5e-15
sp|Q9QYB8|ADDB_MOUSE Beta-adducin (Erythrocyte adducin beta... 80 9e-15
sp|P35612|ADDB_HUMAN Beta-adducin (Erythrocyte adducin beta... 75 3e-13
sp|Q9QYC0|ADDA_MOUSE Alpha-adducin (Erythrocyte adducin alp... 67 6e-11
sp|Q63028|ADDA_RAT Alpha-adducin (Erythrocyte adducin alpha... 67 6e-11
sp|P35611|ADDA_HUMAN Alpha-adducin (Erythrocyte adducin alp... 66 1e-10
sp|Q9UEY8|ADDG_HUMAN Gamma-adducin (Adducin-like protein 70) 56 1e-07
sp|Q9QYB5|ADDG_MOUSE Gamma-adducin (Adducin-like protein 70) 50 6e-06
>sp|Q02645|HTS_DROME Hu-li tai shao protein (Adducin-like protein)
Length = 1156
Score = 102 bits (253), Expect = 2e-21
Identities = 59/170 (34%), Positives = 97/170 (57%), Gaps = 5/170 (2%)
Frame = +1
Query: 34 EQGDEAVKQKQPQTQWLLHTPNDYVREEITENGT---RKVVSWRPVSADSRQTSGLVETC 204
++GD +++ +++WL ++PN Y + E+ E GT +K+ W + + T +E
Sbjct: 434 KKGD--IRKGGDRSRWL-NSPNVYQKVEVLETGTPDPKKITKWVAEGSPTHSTPVRIE-- 488
Query: 205 TSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNV--DQTSEVDGVPDEES 378
P QF P G + E K QQ +K D+ SAG QS +L V D+ S + ++
Sbjct: 489 -DPLQFVPAGTNpreFKRVQQLIKDNRRADKISAGPQSHILEGVTWDEASRLKDATVSQA 547
Query: 379 VGRVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKV 528
VV++GA S+GII + +H+ +VY++ ++ NPFD VTDD+L +YKR V
Sbjct: 548 GDHVVMMGAASKGIIQRGFQHNATVYKAPYAKNPFDNVTDDELNEYKRTV 597
>sp|Q9U9K0|ADD1_CAEEL Adducin-related protein 1
Length = 732
Score = 84.3 bits (207), Expect = 4e-16
Identities = 57/192 (29%), Positives = 97/192 (50%), Gaps = 20/192 (10%)
Frame = +1
Query: 1 PPSSTSFATRTEQGDEAV--------KQKQPQTQWLLHTPNDYVREEITENGT---RKVV 147
PP+++++ E E+V +++Q + +W+ ++PN Y + E E G +K+
Sbjct: 394 PPTTSAYGQIDETNLESVSAHRLALLRKEQERVRWM-NSPNAYQKVEFLEYGADNPKKIT 452
Query: 148 SW-RPVSADSRQTSGLVETCTSPNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRV 324
W V+ S SG +S +QF+P + E K +Q+ +K SAG QS++
Sbjct: 453 KWVHDVNVPS--ASGTPVKISSVHQFSPASSNPKEFKEKQKAIKENNRLGTLSAGPQSQI 510
Query: 325 LRNVDQTS-------EVDGVPDEESVG-RVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNP 480
L +V + DG + S R +L+G S+GIID++ +H VY ++PNP
Sbjct: 511 LDSVTYEDIALLIKPDNDGTVGQSSTADRAILIGTASKGIIDRQFQHHAQVYHQIYAPNP 570
Query: 481 FDRVTDDDLKQY 516
F TD D+K+Y
Sbjct: 571 FSVETDADIKKY 582
>sp|Q05764|ADDB_RAT Beta-adducin (Erythrocyte adducin beta subunit) (Adducin 63)
Length = 725
Score = 80.5 bits (197), Expect = 5e-15
Identities = 61/202 (30%), Positives = 105/202 (51%), Gaps = 7/202 (3%)
Frame = +1
Query: 49 AVKQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRP----VSADS--RQTSGLVETCTS 210
A KQ++ +T+WL +TPN Y+R + + R + S RP + AD + +SG+ +
Sbjct: 423 AQKQQKEKTRWL-NTPNTYLRVNVADEVQRNMGSPRPKTTWMKADEVEKSSSGMPIRIEN 481
Query: 211 PNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEVDGVPDEESVGRV 390
PNQF P D E+ + K++ + +D SAG QS++L +V +E P ES
Sbjct: 482 PNQFVPLYTDPQEVLDMRNKIREQNRQDIKSAGPQSQLLASV--IAEKSRSPSTES---- 535
Query: 391 VLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVLGLPPDEIETSKQE 570
S+G D + + +V PNPF ++TD +L++YK++V ++ + +++
Sbjct: 536 ---QLASKGDADTKDELEETV------PNPFSQLTDQELEEYKKEVERKKLEQEQEGEKD 586
Query: 571 VSFTEP-SVTDTNISSPVDKPT 633
+ EP S + +SPV PT
Sbjct: 587 AATEEPGSPVKSTPASPVQSPT 608
>sp|Q9QYB8|ADDB_MOUSE Beta-adducin (Erythrocyte adducin beta subunit) (Add97)
Length = 725
Score = 79.7 bits (195), Expect = 9e-15
Identities = 59/202 (29%), Positives = 107/202 (52%), Gaps = 7/202 (3%)
Frame = +1
Query: 49 AVKQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRP----VSADS--RQTSGLVETCTS 210
A KQ++ +T+WL +TPN Y+R + + R + S RP + AD + +SG+ +
Sbjct: 423 AQKQQKEKTRWL-NTPNTYLRVNVADEVQRNMGSPRPKTTWMKADEVEKSSSGMPIRIEN 481
Query: 211 PNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEVDGVPDEESVGRV 390
PNQF P D E+ + K++ + +D SAG QS++L +V +E P ES
Sbjct: 482 PNQFVPLYTDPQEVLDMRNKIREQNRQDIKSAGPQSQLLASV--IAEKSRSPSTES---- 535
Query: 391 VLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVLGLPPDEIETSKQE 570
+S+G D + + +V PNPF ++TD +L++YK++V ++ + +++
Sbjct: 536 ---QLMSKGDADTKDESEETV------PNPFSQLTDQELEEYKKEVERKKLEQEQEGEKD 586
Query: 571 VSFTEP-SVTDTNISSPVDKPT 633
++ +P S + +SPV P+
Sbjct: 587 IATEKPGSPVKSTPASPVQSPS 608
>sp|P35612|ADDB_HUMAN Beta-adducin (Erythrocyte adducin beta subunit)
Length = 726
Score = 74.7 bits (182), Expect = 3e-13
Identities = 63/200 (31%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Frame = +1
Query: 49 AVKQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRP----VSADS--RQTSGLVETCTS 210
A KQ++ +T+WL +TPN Y+R + + R + S RP + AD + +SG+ +
Sbjct: 423 AQKQQKEKTRWL-NTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIEN 481
Query: 211 PNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEVDGVPDEESVGRV 390
PNQF P D E+ + K++ + +D SAG QS++L +V +E P ES
Sbjct: 482 PNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASV--IAEKSRSPSTES---- 535
Query: 391 VLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYK----RKVLGLPPDEIET 558
+S+G D + + +V PNPF ++TD +L++YK RK L L E ET
Sbjct: 536 ---QLMSKGDEDTKDDSEETV------PNPFSQLTDQELEEYKKEVERKKLEL-DGEKET 585
Query: 559 SKQEVSFTEPSVTDTNISSP 618
+ +E S + + SP
Sbjct: 586 APEEPGSPAKSAPASPVQSP 605
>sp|Q9QYC0|ADDA_MOUSE Alpha-adducin (Erythrocyte adducin alpha subunit)
Length = 735
Score = 67.0 bits (162), Expect = 6e-11
Identities = 58/195 (29%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Frame = +1
Query: 55 KQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRPVSADSRQTSGLVETCTSPNQFAPQG 234
KQ++ +T+WL D EE +NG+ + D +TS T PN F P
Sbjct: 439 KQQREKTRWLHSGRGDDASEE-GQNGSSPKSKTKWTKEDGHRTS----TSAVPNLFVPLN 493
Query: 235 HDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEVDGVPDEESVGRVVLVGAVSR 414
+ E++ + K++ + +D +AG QS+VL GV + S+ + LV A S+
Sbjct: 494 TNPKEVQEMRNKIREQNLQDIKTAGPQSQVLC---------GVMMDRSLVQGELVTA-SK 543
Query: 415 GIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVLGLPP------DEIETSKQEVS 576
II+K ++ P V S PNPF+ +TD +L++Y+R+V DE K++
Sbjct: 544 AIIEKEYQ--PHVIVSTTGPNPFNTLTDRELEEYRREVERKQKGSEENLDETREQKEKSP 601
Query: 577 FTEPSVTDTNISSPV 621
+ +V +T S+PV
Sbjct: 602 PDQSAVPNTPPSTPV 616
>sp|Q63028|ADDA_RAT Alpha-adducin (Erythrocyte adducin alpha subunit)
Length = 735
Score = 67.0 bits (162), Expect = 6e-11
Identities = 58/195 (29%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Frame = +1
Query: 55 KQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRPVSADSRQTSGLVETCTSPNQFAPQG 234
KQ++ +T+WL D EE +NG+ + D +TS T PN F P
Sbjct: 439 KQQREKTRWLNSGRGDDASEE-GQNGSSPKSKTKWTKEDGHRTS----TSAVPNLFVPLN 493
Query: 235 HDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEVDGVPDEESVGRVVLVGAVSR 414
+ E++ + K++ + +D +AG QS+VL GV + S+ + LV A S+
Sbjct: 494 TNPKEVQEMRNKIREQNLQDIKTAGPQSQVLC---------GVMMDRSLVQGELVTA-SK 543
Query: 415 GIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVLGLPP------DEIETSKQEVS 576
II+K ++ P V S PNPF+ +TD +L++Y+R+V DE K++
Sbjct: 544 AIIEKEYQ--PHVIVSTTGPNPFNTLTDRELEEYRREVERKQKGSEENLDETREQKEKSP 601
Query: 577 FTEPSVTDTNISSPV 621
+ +V +T S+PV
Sbjct: 602 PDQSAVPNTPPSTPV 616
>sp|P35611|ADDA_HUMAN Alpha-adducin (Erythrocyte adducin alpha subunit)
Length = 737
Score = 66.2 bits (160), Expect = 1e-10
Identities = 57/195 (29%), Positives = 94/195 (48%), Gaps = 6/195 (3%)
Frame = +1
Query: 55 KQKQPQTQWLLHTPNDYVREEITENGTRKVVSWRPVSADSRQTSGLVETCTSPNQFAPQG 234
KQ++ +T+WL D EE +NG+ + D +TS T PN F P
Sbjct: 439 KQQREKTRWLNSGRGDEASEE-GQNGSSPKSKTKWTKEDGHRTS----TSAVPNLFVPLN 493
Query: 235 HDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEVDGVPDEESVGRVVLVGAVSR 414
+ E++ + K++ + +D +AG QS+VL GV + S+ + LV A S+
Sbjct: 494 TNPKEVQEMRNKIREQNLQDIKTAGPQSQVLC---------GVVMDRSLVQGELVTA-SK 543
Query: 415 GIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVLGLPP------DEIETSKQEVS 576
II+K ++ P V S PNPF +TD +L++Y+R+V DE K++
Sbjct: 544 AIIEKEYQ--PHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSP 601
Query: 577 FTEPSVTDTNISSPV 621
+P+V S+P+
Sbjct: 602 PDQPAVPHPPPSTPI 616
>sp|Q9UEY8|ADDG_HUMAN Gamma-adducin (Adducin-like protein 70)
Length = 706
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/202 (23%), Positives = 91/202 (45%), Gaps = 8/202 (3%)
Frame = +1
Query: 49 AVKQKQPQTQWLLHTPNDYVREEITE---NGT---RKVVSWRPVSADSRQTSGLVETCTS 210
A +Q++ +T+WL ++PN Y++ + E NG R ++W S+ + G
Sbjct: 429 AQRQQREKTRWL-NSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSGGTPIKIED 487
Query: 211 PNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRN--VDQTSEVDGVPDEESVG 384
PNQF P + +E+ ++ K++ + D +AG QS++L VD+ D++
Sbjct: 488 PNQFVPLNTNPNEVLEKRNKIREQNRYDLKTAGPQSQLLAGIVVDKPPSTMQFEDDD--- 544
Query: 385 RVVLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQYKRKVLGLPPDEIETSK 564
H P PNPF +T+ +L++YKR + +E ++
Sbjct: 545 ------------------HGPPA-----PPNPFSHLTEGELEEYKR-TIERKQQGLEDAE 580
Query: 565 QEVSFTEPSVTDTNISSPVDKP 630
QE+ ++ + + + I S P
Sbjct: 581 QEL-LSDDASSVSQIQSQTQSP 601
>sp|Q9QYB5|ADDG_MOUSE Gamma-adducin (Adducin-like protein 70)
Length = 706
Score = 50.4 bits (119), Expect = 6e-06
Identities = 51/204 (25%), Positives = 86/204 (42%), Gaps = 10/204 (4%)
Frame = +1
Query: 49 AVKQKQPQTQWLLHTPNDYVREEITE---NGT---RKVVSWRPVSADSRQTSGLVETCTS 210
A +Q++ +T+WL ++PN Y++ + E NG R ++W S+ +SG
Sbjct: 429 AQRQQREKTRWL-NSPNTYMKVNVPEESRNGETSPRTKITWMKAEDSSKVSSGTPIKIED 487
Query: 211 PNQFAPQGHDKHELKHQQQKVKGKYFRDETSAGHQSRVLRNVDQTSEVDGVPDEESVGRV 390
PNQF P + E+ ++ K++ + D +AG QS++L + VD P
Sbjct: 488 PNQFVPLNTNPTEVLEKRNKIREQNRYDLKTAGPQSQLLAGI----VVDKPP-------- 535
Query: 391 VLVGAVSRGIIDKRHRHDPSVYQSCFSPNPFDRVTDDDLKQY----KRKVLGLPPDEIET 558
S D + P+ PNPF + + +L++Y +RK GL D+ E
Sbjct: 536 ------STMQFDDDDQGPPA------PPNPFSHLLEGELEEYTKTIERKQQGL--DDAEQ 581
Query: 559 SKQEVSFTEPSVTDTNISSPVDKP 630
S + SP P
Sbjct: 582 GSLSDDAASVSQIQSQTQSPQSVP 605
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.309 0.126 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,077,101
Number of Sequences: 369166
Number of extensions: 1422832
Number of successful extensions: 3471
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3348
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3461
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8100769320
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)