Planaria EST Database

DrC_00523

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00523
         (1115 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P07711|CATL_HUMAN  Cathepsin L precursor (Major excreted ...   283   8e-76
sp|O60911|CATL2_HUMAN  Cathepsin L2 precursor (Cathepsin V) ...   280   5e-75
sp|Q9GL24|CATL_CANFA  Cathepsin L precursor [Contains: Cathe...   274   4e-73
sp|Q28944|CATL_PIG  Cathepsin L precursor [Contains: Catheps...   271   2e-72
sp|P07154|CATL_RAT  Cathepsin L precursor (Major excreted pr...   269   9e-72
sp|P25975|CATL_BOVIN  Cathepsin L precursor [Contains: Cathe...   269   1e-71
sp|P43236|CATK_RABIT  Cathepsin K precursor (OC-2 protein)        267   5e-71
sp|P43235|CATK_HUMAN  Cathepsin K precursor (Cathepsin O) (C...   264   4e-70
sp|P55097|CATK_MOUSE  Cathepsin K precursor                       263   5e-70
sp|O35186|CATK_RAT  Cathepsin K precursor                         263   5e-70

>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
           Cathepsin L heavy chain; Cathepsin L light chain]
          Length = 333

 Score =  283 bits (723), Expect = 8e-76
 Identities = 145/323 (44%), Positives = 195/323 (60%), Gaps = 8/323 (2%)
 Frame = +2

Query: 2   LSNGAYKIDLQLNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHS 181
           +++     D  L  QW  +K   N+ Y     E  RR +WE N+K IE HN EY  G HS
Sbjct: 14  IASATLTFDHSLEAQWTKWKAMHNRLY-GMNEEGWRRAVWEKNMKMIELHNQEYREGKHS 72

Query: 182 FTLGANEFSDLSHEEFKSIYLMKEFIPPKTENIYXXXXXXXXXXXXVNWQKQGYVTSVKD 361
           FT+  N F D++ EEF+ +    +   P+   ++            V+W+++GYVT VK+
Sbjct: 73  FTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRS-VDWREKGYVTPVKN 131

Query: 362 QTRTCGSCWAFSTTGSLEGQFYRKYKRLVSLSEQQLVDCD--MKSYGCYGGWVEDAVDYI 535
           Q + CGSCWAFS TG+LEGQ +RK  RL+SLSEQ LVDC     + GC GG ++ A  Y+
Sbjct: 132 QGQ-CGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYV 190

Query: 536 TQTGGIESEDDYPYLAKASLCKFNKSKIVARTAGYTTIEKNEIALAEALVNVGPISIIID 715
              GG++SE+ YPY A    CK+N    VA   G+  I K E AL +A+  VGPIS+ ID
Sbjct: 191 QDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAID 250

Query: 716 ASHRSFQLYKDGIYDEPQC-TEKVDHAVLLVGYG-----EEKSKYWIVKNSWGRKWGKNG 877
           A H SF  YK+GIY EP C +E +DH VL+VGYG      + +KYW+VKNSWG +WG  G
Sbjct: 251 AGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGG 310

Query: 878 YIWMSKDKENQCSIASYAGFPKI 946
           Y+ M+KD+ N C IAS A +P +
Sbjct: 311 YVKMAKDRRNHCGIASAASYPTV 333

>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
          Length = 334

 Score =  280 bits (716), Expect = 5e-75
 Identities = 146/327 (44%), Positives = 200/327 (61%), Gaps = 12/327 (3%)
 Frame = +2

Query: 2   LSNGAYKIDLQLNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHS 181
           +++   K D  L+ +W  +K T  + Y     E  RR +WE N+K IE HN EY  G H 
Sbjct: 14  IASAVPKFDQNLDTKWYQWKATHRRLY-GANEEGWRRAVWEKNMKMIELHNGEYSQGKHG 72

Query: 182 FTLGANEFSDLSHEEFKSI---YLMKEFIPPKTENIYXXXXXXXXXXXXVNWQKQGYVTS 352
           FT+  N F D+++EEF+ +   +  ++F   K                 V+W+K+GYVT 
Sbjct: 73  FTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKV----FREPLFLDLPKSVDWRKKGYVTP 128

Query: 353 VKDQTRTCGSCWAFSTTGSLEGQFYRKYKRLVSLSEQQLVDCDMK--SYGCYGGWVEDAV 526
           VK+Q + CGSCWAFS TG+LEGQ +RK  +LVSLSEQ LVDC     + GC GG++  A 
Sbjct: 129 VKNQ-KQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAF 187

Query: 527 DYITQTGGIESEDDYPYLAKASLCKFNKSKIVARTAGYTTIEKN-EIALAEALVNVGPIS 703
            Y+ + GG++SE+ YPY+A   +CK+     VA   G+T +    E AL +A+  VGPIS
Sbjct: 188 QYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPIS 247

Query: 704 IIIDASHRSFQLYKDGIYDEPQCTEK-VDHAVLLVGYGEE-----KSKYWIVKNSWGRKW 865
           + +DA H SFQ YK GIY EP C+ K +DH VL+VGYG E      SKYW+VKNSWG +W
Sbjct: 248 VAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEW 307

Query: 866 GKNGYIWMSKDKENQCSIASYAGFPKI 946
           G NGY+ ++KDK N C IA+ A +P +
Sbjct: 308 GSNGYVKIAKDKNNHCGIATAASYPNV 334

>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 333

 Score =  274 bits (700), Expect = 4e-73
 Identities = 144/324 (44%), Positives = 198/324 (61%), Gaps = 9/324 (2%)
 Frame = +2

Query: 2   LSNGAYKIDLQLNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHS 181
           +++ A K D  LN QW  +K T  + Y     E  RR +WE N+K IE HN EY  G H 
Sbjct: 14  IASAAPKFDQSLNAQWYQWKATHRRLY-GMNEEGWRRAVWEKNMKMIELHNREYSQGKHG 72

Query: 182 FTLGANEFSDLSHEEFKSIYLMKEFIPPK-TENIYXXXXXXXXXXXXVNWQKQGYVTSVK 358
           FT+  N F D+++EEF+ +  M  F   K  +               V+W+++GYVT VK
Sbjct: 73  FTMAMNAFGDMTNEEFRQV--MNGFQNQKHKKGKMFQEPLFAEIPKSVDWREKGYVTPVK 130

Query: 359 DQTRTCGSCWAFSTTGSLEGQFYRKYKRLVSLSEQQLVDCDMK--SYGCYGGWVEDAVDY 532
           +Q + CGSCWAFS TG+LEGQ +RK  +LVSLSEQ LVDC     + GC GG +++A  Y
Sbjct: 131 NQGQ-CGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGLMDNAFRY 189

Query: 533 ITQTGGIESEDDYPYLAK-ASLCKFNKSKIVARTAGYTTIEKNEIALAEALVNVGPISII 709
           +   GG++SE+ YPYL +    C +      A   G+  + + E AL +A+  +GPIS+ 
Sbjct: 190 VKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQREKALMKAVATLGPISVA 249

Query: 710 IDASHRSFQLYKDGIYDEPQCTEK-VDHAVLLVGYGEE----KSKYWIVKNSWGRKWGKN 874
           IDA H+SFQ YK GIY +P C+ K +DH VL+VGYG E     +K+WIVKNSWG +WG N
Sbjct: 250 IDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGPEWGWN 309

Query: 875 GYIWMSKDKENQCSIASYAGFPKI 946
           GY+ M+KD+ N C IA+ A +P +
Sbjct: 310 GYVKMAKDQNNHCGIATAASYPTV 333

>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  271 bits (693), Expect = 2e-72
 Identities = 140/324 (43%), Positives = 199/324 (61%), Gaps = 9/324 (2%)
 Frame = +2

Query: 2   LSNGAYKIDLQLNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHS 181
           +++ A K+D  L+  W  +K T  + Y     E  RR +WE N+K IE HN EY  G H 
Sbjct: 14  IASAAPKLDQNLDADWYKWKATHGRLY-GMNEEGWRRAVWEKNMKMIELHNQEYSQGKHG 72

Query: 182 FTLGANEFSDLSHEEFKSIYLMKEFIPPKTENIYXXXXXXXXXXXXVNWQKQGYVTSVKD 361
           F++  N F D+++EEF+ +    +    K   ++            V+W+++GYVT+VK+
Sbjct: 73  FSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVLEVPKS-VDWREKGYVTAVKN 131

Query: 362 QTRTCGSCWAFSTTGSLEGQFYRKYKRLVSLSEQQLVDCDMK--SYGCYGGWVEDAVDYI 535
           Q + CGSCWAFS TG+LEGQ +RK  +LVSLSEQ LVDC     + GC GG +++A  Y+
Sbjct: 132 QGQ-CGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYV 190

Query: 536 TQTGGIESEDDYPYLAK-ASLCKFNKSKIVARTAGYTTIEKNEIALAEALVNVGPISIII 712
              GG+++E+ YPYL +  + C +      A   G+  I + E AL +A+  VGPIS+ I
Sbjct: 191 KDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAI 250

Query: 713 DASHRSFQLYKDGIYDEPQCTEK-VDHAVLLVGYGEE-----KSKYWIVKNSWGRKWGKN 874
           DA H SFQ YK GIY +P C+ K +DH VL+VGYG E      SK+WIVKNSWG +WG N
Sbjct: 251 DAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWN 310

Query: 875 GYIWMSKDKENQCSIASYAGFPKI 946
           GY+ M+KD+ N C I++ A +P +
Sbjct: 311 GYVKMAKDQNNHCGISTAASYPTV 334

>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
           protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
           Cathepsin L light chain]
          Length = 334

 Score =  269 bits (688), Expect = 9e-72
 Identities = 140/315 (44%), Positives = 190/315 (60%), Gaps = 8/315 (2%)
 Frame = +2

Query: 20  KIDLQLNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHSFTLGAN 199
           K D   N QW  +K T  + Y     E  RR +WE N++ I+ HN EY  G H FT+  N
Sbjct: 20  KFDQTFNAQWHQWKSTHRRLYGTNEEEW-RRAVWEKNMRMIQLHNGEYSNGKHGFTMEMN 78

Query: 200 EFSDLSHEEFKSIYLMKEFIPPKTENIYXXXXXXXXXXXXVNWQKQGYVTSVKDQTRTCG 379
            F D+++EEF+ I         K   ++            V+W+++G VT VK+Q + CG
Sbjct: 79  AFGDMTNEEFRQIVNGYRHQKHKKGRLFQEPLMLQIPKT-VDWREKGCVTPVKNQGQ-CG 136

Query: 380 SCWAFSTTGSLEGQFYRKYKRLVSLSEQQLVDC--DMKSYGCYGGWVEDAVDYITQTGGI 553
           SCWAFS +G LEGQ + K  +L+SLSEQ LVDC  D  + GC GG ++ A  YI + GG+
Sbjct: 137 SCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQYIKENGGL 196

Query: 554 ESEDDYPYLAKASLCKFNKSKIVARTAGYTTIEKNEIALAEALVNVGPISIIIDASHRSF 733
           +SE+ YPY AK   CK+     VA   G+  I + E AL +A+  VGPIS+ +DASH S 
Sbjct: 197 DSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQQEKALMKAVATVGPISVAMDASHPSL 256

Query: 734 QLYKDGIYDEPQCTEK-VDHAVLLVGYGEE-----KSKYWIVKNSWGRKWGKNGYIWMSK 895
           Q Y  GIY EP C+ K +DH VL+VGYG E     K KYW+VKNSWG++WG +GYI ++K
Sbjct: 257 QFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAK 316

Query: 896 DKENQCSIASYAGFP 940
           D+ N C +A+ A +P
Sbjct: 317 DRNNHCGLATAASYP 331

>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  269 bits (687), Expect = 1e-71
 Identities = 143/324 (44%), Positives = 196/324 (60%), Gaps = 9/324 (2%)
 Frame = +2

Query: 2   LSNGAYKIDLQLNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHS 181
           +++ A K+D  L+  W  +K T  + Y     E  RR +WE N K I+ HN EY  G H+
Sbjct: 14  VASAAPKLDPNLDAHWHQWKATHRRLY-GMNEEEWRRAVWEKNKKIIDLHNQEYSEGKHA 72

Query: 182 FTLGANEFSDLSHEEFKSIYLMKEFIPPKTENIYXXXXXXXXXXXXVNWQKQGYVTSVKD 361
           F +  N F D+++EEF+ +    +    K   ++            V+W K+GYVT VK+
Sbjct: 73  FRMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKLFHEPLLVDVPKS-VDWTKKGYVTPVKN 131

Query: 362 QTRTCGSCWAFSTTGSLEGQFYRKYKRLVSLSEQQLVDCDMK--SYGCYGGWVEDAVDYI 535
           Q + CGSCWAFS TG+LEGQ +RK  +LVSLSEQ LVDC     + GC GG +++A  YI
Sbjct: 132 QGQ-CGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNGGLMDNAFQYI 190

Query: 536 TQTGGIESEDDYPYLAK-ASLCKFNKSKIVARTAGYTTIEKNEIALAEALVNVGPISIII 712
              GG++SE+ YPYLA   + C +      A   G+  I + E AL +A+  VGPIS+ I
Sbjct: 191 KDNGGLDSEESYPYLATDTNSCNYKPECSAANDTGFVDIPQREKALMKAVATVGPISVAI 250

Query: 713 DASHRSFQLYKDGIYDEPQCTEK-VDHAVLLVGYGEE-----KSKYWIVKNSWGRKWGKN 874
           DA H SFQ YK GIY +P C+ K +DH VL+VGYG E      +K+WIVKNSWG +WG N
Sbjct: 251 DAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKNSWGPEWGWN 310

Query: 875 GYIWMSKDKENQCSIASYAGFPKI 946
           GY+ M+KD+ N C IA+ A +P +
Sbjct: 311 GYVKMAKDQNNHCGIATAASYPTV 334

>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
          Length = 329

 Score =  267 bits (682), Expect = 5e-71
 Identities = 136/311 (43%), Positives = 199/311 (63%), Gaps = 7/311 (2%)
 Frame = +2

Query: 35  LNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHSFTLGANEFSDL 214
           L+ QW ++K+T++K Y +   EI RR IWE NLK+I  HN E  +G+H++ L  N   D+
Sbjct: 22  LDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDM 81

Query: 215 SHEEF-KSIYLMKEFIPPK---TENIYXXXXXXXXXXXXVNWQKQGYVTSVKDQTRTCGS 382
           + EE  + +  +K  +PP    + +              ++++K+GYVT VK+Q + CGS
Sbjct: 82  TSEEVVQKMTGLK--VPPSRSHSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQ-CGS 138

Query: 383 CWAFSTTGSLEGQFYRKYKRLVSLSEQQLVDCDMKSYGCYGGWVEDAVDYITQTGGIESE 562
           CWAFS+ G+LEGQ  +K  +L++LS Q LVDC  ++YGC GG++ +A  Y+ +  GI+SE
Sbjct: 139 CWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENYGCGGGYMTNAFQYVQRNRGIDSE 198

Query: 563 DDYPYLAKASLCKFNKSKIVARTAGYTTI-EKNEIALAEALVNVGPISIIIDASHRSFQL 739
           D YPY+ +   C +N +   A+  GY  I E NE AL  A+  VGP+S+ IDAS  SFQ 
Sbjct: 199 DAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF 258

Query: 740 YKDGIYDEPQC-TEKVDHAVLLVGYGEEK-SKYWIVKNSWGRKWGKNGYIWMSKDKENQC 913
           Y  G+Y +  C ++ V+HAVL VGYG +K +K+WI+KNSWG  WG  GYI M+++K N C
Sbjct: 259 YSKGVYYDENCSSDNVNHAVLAVGYGIQKGNKHWIIKNSWGESWGNKGYILMARNKNNAC 318

Query: 914 SIASYAGFPKI 946
            IA+ A FPK+
Sbjct: 319 GIANLASFPKM 329

>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2)
          Length = 329

 Score =  264 bits (674), Expect = 4e-70
 Identities = 135/309 (43%), Positives = 191/309 (61%), Gaps = 5/309 (1%)
 Frame = +2

Query: 35  LNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHSFTLGANEFSDL 214
           L+  W ++K+T  K Y N   EI RR IWE NLKYI  HN E  +G+H++ L  N   D+
Sbjct: 22  LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 81

Query: 215 SHEEF--KSIYLMKEFIPPKTENIYXXXXXXXXXXXXVNWQKQGYVTSVKDQTRTCGSCW 388
           + EE   K   L       ++ +              V+++K+GYVT VK+Q + CGSCW
Sbjct: 82  TSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ-CGSCW 140

Query: 389 AFSTTGSLEGQFYRKYKRLVSLSEQQLVDCDMKSYGCYGGWVEDAVDYITQTGGIESEDD 568
           AFS+ G+LEGQ  +K  +L++LS Q LVDC  ++ GC GG++ +A  Y+ +  GI+SED 
Sbjct: 141 AFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDA 200

Query: 569 YPYLAKASLCKFNKSKIVARTAGYTTI-EKNEIALAEALVNVGPISIIIDASHRSFQLYK 745
           YPY+ +   C +N +   A+  GY  I E NE AL  A+  VGP+S+ IDAS  SFQ Y 
Sbjct: 201 YPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYS 260

Query: 746 DGIYDEPQC-TEKVDHAVLLVGYGEEK-SKYWIVKNSWGRKWGKNGYIWMSKDKENQCSI 919
            G+Y +  C ++ ++HAVL VGYG +K +K+WI+KNSWG  WG  GYI M+++K N C I
Sbjct: 261 KGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGI 320

Query: 920 ASYAGFPKI 946
           A+ A FPK+
Sbjct: 321 ANLASFPKM 329

>sp|P55097|CATK_MOUSE Cathepsin K precursor
          Length = 329

 Score =  263 bits (673), Expect = 5e-70
 Identities = 136/310 (43%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
 Frame = +2

Query: 35  LNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHSFTLGANEFSDL 214
           L+ QW ++K+T  K Y +   EI RR IWE NLK I  HN E  +G+H++ L  N   D+
Sbjct: 22  LDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLGDM 81

Query: 215 SHEEFKSIYLMKEFIPPK---TENIYXXXXXXXXXXXXVNWQKQGYVTSVKDQTRTCGSC 385
           + EE     +    IPP    + +              ++++K+GYVT VK+Q + CGSC
Sbjct: 82  TSEEVVQ-KMTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQ-CGSC 139

Query: 386 WAFSTTGSLEGQFYRKYKRLVSLSEQQLVDCDMKSYGCYGGWVEDAVDYITQTGGIESED 565
           WAFS+ G+LEGQ  +K  +L++LS Q LVDC  ++YGC GG++  A  Y+ Q GGI+SED
Sbjct: 140 WAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENYGCGGGYMTTAFQYVQQNGGIDSED 199

Query: 566 DYPYLAKASLCKFNKSKIVARTAGYTTIE-KNEIALAEALVNVGPISIIIDASHRSFQLY 742
            YPY+ +   C +N +   A+  GY  I   NE AL  A+  VGPIS+ IDAS  SFQ Y
Sbjct: 200 AYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQFY 259

Query: 743 KDGIYDEPQC-TEKVDHAVLLVGYGEEK-SKYWIVKNSWGRKWGKNGYIWMSKDKENQCS 916
             G+Y +  C  + V+HAVL+VGYG +K SK+WI+KNSWG  WG  GY  ++++K N C 
Sbjct: 260 SRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKNNACG 319

Query: 917 IASYAGFPKI 946
           I + A FPK+
Sbjct: 320 ITNMASFPKM 329

>sp|O35186|CATK_RAT Cathepsin K precursor
          Length = 329

 Score =  263 bits (673), Expect = 5e-70
 Identities = 134/310 (43%), Positives = 190/310 (61%), Gaps = 6/310 (1%)
 Frame = +2

Query: 35  LNDQWRIYKETFNKTYRNPFHEIERREIWEDNLKYIEKHNYEYFVGLHSFTLGANEFSDL 214
           L+ QW ++K+T  K Y +   EI RR IWE NLK I  HN E  +G H++ L  N   D+
Sbjct: 22  LDTQWELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVHNLEASLGAHTYELAMNHLGDM 81

Query: 215 SHEEFKSIYLMKEFIPPK---TENIYXXXXXXXXXXXXVNWQKQGYVTSVKDQTRTCGSC 385
           + EE     +    +PP    + +              ++++K+GYVT VK+Q + CGSC
Sbjct: 82  TSEEVVQ-KMTGLRVPPSRSFSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQ-CGSC 139

Query: 386 WAFSTTGSLEGQFYRKYKRLVSLSEQQLVDCDMKSYGCYGGWVEDAVDYITQTGGIESED 565
           WAFS+ G+LEGQ  +K  +L++LS Q LVDC  ++YGC GG++  A  Y+ Q GGI+SED
Sbjct: 140 WAFSSAGALEGQLKKKTGKLLALSPQNLVDCVSENYGCGGGYMTTAFQYVQQNGGIDSED 199

Query: 566 DYPYLAKASLCKFNKSKIVARTAGYTTIE-KNEIALAEALVNVGPISIIIDASHRSFQLY 742
            YPY+ +   C +N +   A+  GY  I   NE AL  A+  VGP+S+ IDAS  SFQ Y
Sbjct: 200 AYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPVSVSIDASLTSFQFY 259

Query: 743 KDGIYDEPQC-TEKVDHAVLLVGYGEEK-SKYWIVKNSWGRKWGKNGYIWMSKDKENQCS 916
             G+Y +  C  + V+HAVL+VGYG +K +KYWI+KNSWG  WG  GY+ ++++K N C 
Sbjct: 260 SRGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIKNSWGESWGNKGYVLLARNKNNACG 319

Query: 917 IASYAGFPKI 946
           I + A FPK+
Sbjct: 320 ITNLASFPKM 329

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 123,494,143
Number of Sequences: 369166
Number of extensions: 2462891
Number of successful extensions: 6652
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5679
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5932
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 12345146940
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00523

  1. Dr_sW_013_L02
  2. Dr_sW_024_G04
  3. Dr_sW_003_M23