Planaria EST Database


DrC_00463

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00463
         (1138 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q5R4J9|NARG1_PONPY  NMDA receptor regulated protein 1           95   3e-19
sp|Q9BXJ9|NARG1_HUMAN  NMDA receptor regulated protein 1 (N-...    94   7e-19
sp|Q80UM3|NARG1_MOUSE  NMDA receptor regulated protein 1 (N-...    92   4e-18
sp|Q6N069|NARGL_HUMAN  NMDA receptor regulated 1-like protei...    89   3e-17
sp|Q9DBB4|NARGL_MOUSE  NMDA receptor regulated 1-like protei...    84   6e-16
sp|Q14511|CASL_HUMAN  Enhancer of filamentation 1 (HEF1) (CR...    35   0.31 
sp|O93379|P53_ICTPU  Cellular tumor antigen p53 (Tumor suppr...    33   1.5  
sp|O35177|CASL_MOUSE  Enhancer of filamentation 1 (MEF1) (CR...    32   2.6  
sp|Q895G1|KCY_CLOTE  Cytidylate kinase (CK) (Cytidine monoph...    32   2.6  
sp|P08032|SPTA1_MOUSE  Spectrin alpha chain, erythrocyte (Er...    32   2.6  
>sp|Q5R4J9|NARG1_PONPY NMDA receptor regulated protein 1
          Length = 866

 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 74/244 (30%), Positives = 118/244 (48%), Gaps = 3/244 (1%)
 Frame = +2

Query: 74   AENEALKKQQEQEKRDQIQKLKTQDK-EDMEMAEEKIDGSKLIKTTAPLDEAVKFLQPLL 250
            A+ E  KK  E+EK+ + QK K  D  E++   +E++   KL K   PL+EA+KFL PL 
Sbjct: 606  AQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLK 665

Query: 251  TLTPRNIDSLCLAFKIYEKKNKILLMLKAIKSGLRIPNSLENPYFYECFIKFLIIVKQKL 430
             L    I++   AF+IY +K K LLML+++K    I +S  +P+ +EC I+       + 
Sbjct: 666  NLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSS--HPWLHECMIRLFNTAVCES 723

Query: 431  PTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFSNKNKASILHQFYAWHLGNIIRNCV 610
                +TVRTV++  M    H L          + F  +N  S+ H+  A  +   +    
Sbjct: 724  KDLSDTVRTVLKQEM----HRLFGATNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSS 779

Query: 611  QNCDYSTLESSLNRPPANGSWKDCEIVLNKLKD--VYNLKEKDSVYNSLREKFSVTFPFC 784
            Q      L ++L+    N + + C  VL  L D  + + KE   +Y +   K    FP+ 
Sbjct: 780  QKRAIE-LATTLDESLTNRNLQTCMEVLETLYDGSLGDCKEAAEIYRANCHKL---FPYA 835

Query: 785  SSFM 796
             +FM
Sbjct: 836  LAFM 839
>sp|Q9BXJ9|NARG1_HUMAN NMDA receptor regulated protein 1 (N-terminal acetyltransferase)
            (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen
            Ga19)
          Length = 866

 Score = 94.0 bits (232), Expect = 7e-19
 Identities = 74/244 (30%), Positives = 119/244 (48%), Gaps = 3/244 (1%)
 Frame = +2

Query: 74   AENEALKKQQEQEKRDQIQKLKTQDK-EDMEMAEEKIDGSKLIKTTAPLDEAVKFLQPLL 250
            A+ E  KK  E+EK+ + QK K  D  E++   +E++   KL K   PL+EA+KFL PL 
Sbjct: 606  AQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLK 665

Query: 251  TLTPRNIDSLCLAFKIYEKKNKILLMLKAIKSGLRIPNSLENPYFYECFIKFLIIVKQKL 430
             L    I++   AF+IY +K K LLML+++K    I +S  +P+ +EC I+       + 
Sbjct: 666  NLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSS--HPWLHECMIRLFNTAVCES 723

Query: 431  PTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFSNKNKASILHQFYAWHLGNIIRNCV 610
                +TVRTV++  M  L    +  N      + F  +N  S+ H+  A  +   +    
Sbjct: 724  KDLSDTVRTVLKQEMNRLFGATNPKN----FNETFLKRNSDSLPHRLSAAKMVYYLDPSS 779

Query: 611  QNCDYSTLESSLNRPPANGSWKDCEIVLNKLKD--VYNLKEKDSVYNSLREKFSVTFPFC 784
            Q      L ++L+    N + + C  VL  L D  + + KE   +Y +   K    FP+ 
Sbjct: 780  QKRAIE-LATTLDESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKL---FPYA 835

Query: 785  SSFM 796
             +FM
Sbjct: 836  LAFM 839
>sp|Q80UM3|NARG1_MOUSE NMDA receptor regulated protein 1 (N-terminal aceyltransferase 1)
            (Tubedown-1 protein)
          Length = 865

 Score = 91.7 bits (226), Expect = 4e-18
 Identities = 76/246 (30%), Positives = 121/246 (49%), Gaps = 5/246 (2%)
 Frame = +2

Query: 74   AENEALKKQQEQEKRDQIQKLKTQDK-EDMEMAEEKIDGSKLIKTTAPLDEAVKFLQPLL 250
            A+ E  KK  E+EK+ + QK K  D  E++   +E++   KL K   PL+EA+KFL PL 
Sbjct: 606  AQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLK 665

Query: 251  TLTPRNIDSLCLAFKIYEKKNKILLMLKAIKSGLRIPNSLENPYFYECFIKFL--IIVKQ 424
             L    I++   AF+IY +K K LLML+++K    I +   +P+ +EC I+    +   +
Sbjct: 666  NLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSG--HPWLHECMIRLFHSVCESK 723

Query: 425  KLPTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFSNKNKASILHQFYAWHLGNIIRN 604
             LP   ETVRTV++  M  L    +  N      + F  +N  S+ H+  A  +   + +
Sbjct: 724  DLP---ETVRTVLKQEMNRLFGATNPKN----FNETFLKRNSDSLPHRLSAAKMVYYLDS 776

Query: 605  CVQNCDYSTLESSLNRPPANGSWKDCEIVLNKLKD--VYNLKEKDSVYNSLREKFSVTFP 778
              Q      L ++L+    N + + C  VL  L D  + + KE    Y +   K    FP
Sbjct: 777  SSQKRAIE-LATTLDGSLTNRNLQTCMEVLEALCDGSLGDCKEAAEAYRASCHKL---FP 832

Query: 779  FCSSFM 796
            +  +FM
Sbjct: 833  YALAFM 838
>sp|Q6N069|NARGL_HUMAN NMDA receptor regulated 1-like protein (NARG1-like protein)
          Length = 864

 Score = 88.6 bits (218), Expect = 3e-17
 Identities = 76/300 (25%), Positives = 129/300 (43%), Gaps = 16/300 (5%)
 Frame = +2

Query: 2    LNIENL*ISEAXXXXXXXXXXXXXAENEALKKQQEQEKRDQIQKLKT-QDKEDMEMAEEK 178
            +N ENL   E              A+ E  +K  E+E++ + QK K  +++E+    +E+
Sbjct: 582  INSENLSAKELKKMLSKQRRAQKKAKLEEERKHAERERQQKNQKKKRDEEEEEASGLKEE 641

Query: 179  IDGSKLIKTTAPLDEAVKFLQPLLTLTPRNIDSLCLAFKIYEKKNKILLMLKAIKSGLRI 358
            +   KL +   PL+EAVKFL PL  L   NID+  LAF+IY +K K LLML+++K    I
Sbjct: 642  LIPEKLERVENPLEEAVKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAI 701

Query: 359  PNSLENPYFYECFIKFLIIVKQKLPTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFS 538
             ++  NP+ +EC I+F      K  +    +  ++   +      +          ++F 
Sbjct: 702  NSN--NPWLHECLIRF-----SKSVSNHSNLPDIVSKVLSQEMQKIFVKKDLESFNEDFL 754

Query: 539  NKNKASILH---------------QFYAWHLGNIIRNCVQNCDYSTLESSLNRPPANGSW 673
             +N  S+ H               Q  A  +   +   +++ D  TL   ++    +GS+
Sbjct: 755  KRNATSLQHLLSGAKMMYFLDKSRQEKAIAIATRLDETIKDKDVKTL-IKVSEALLDGSF 813

Query: 674  KDCEIVLNKLKDVYNLKEKDSVYNSLREKFSVTFPFCSSFMTSVQFKDNQNTPVVTTASH 853
             +C                 S Y   R       PF S+F+ +V   DN N  +  TA++
Sbjct: 814  GNC----------------SSQYEEYRMACHNLLPFTSAFLPAVNEVDNPNVALNHTANY 857
>sp|Q9DBB4|NARGL_MOUSE NMDA receptor regulated 1-like protein (NARG1-like protein)
          Length = 864

 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 61/191 (31%), Positives = 97/191 (50%), Gaps = 3/191 (1%)
 Frame = +2

Query: 2    LNIENL*ISEAXXXXXXXXXXXXXAENEALKKQQEQEKRDQIQKLKTQDKEDMEMA-EEK 178
            ++ ENL   E              A+ E  +K  E+E++ + QK K +++E++    +E+
Sbjct: 582  IDSENLSAKEMKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKREEEEEVTSGHKEE 641

Query: 179  IDGSKLIKTTAPLDEAVKFLQPLLTLTPRNIDSLCLAFKIYEKKNKILLMLKAIKSGLRI 358
            +   KL +   PL+EA+KFL PL TL   +ID+  LAF+IY +K K LLML+++K    I
Sbjct: 642  LIPEKLERVDNPLEEAIKFLTPLKTLAAESIDTHLLAFEIYFRKGKFLLMLQSVKRAFAI 701

Query: 359  PNSLENPYFYECFIKFLIIVK--QKLPTTGETVRTVIETAMKDLPHGLDAMNKCSEITQE 532
             ++  NP+ +EC IKF   V     LP   + V  V+   MK +    D         ++
Sbjct: 702  ESN--NPWLHECLIKFSKSVSNHSNLP---DIVSKVLAQEMKKIFVNKD----LHSFNED 752

Query: 533  FSNKNKASILH 565
            F   N  S+ H
Sbjct: 753  FLRHNATSLQH 763
>sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related
            protein) (CAS-L) (CasL) (p105) (Protein NEDD9)
          Length = 834

 Score = 35.4 bits (80), Expect = 0.31
 Identities = 32/165 (19%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
 Frame = +2

Query: 92   KKQQEQEKRDQIQKLKTQDKEDMEMAEEKIDGSKLIKT--TAPLDEAVKFLQPLLTLTPR 265
            K++ E+++++ ++K     +  M++   ++   +L++   T P++  +   +P  +L   
Sbjct: 637  KEEFERQQKELLEKENIMKQNKMQLEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTT 696

Query: 266  NI-----DSLCLAFKIYEKKNKILLMLKAIKSGLRIPNSLENPYFYECFIKFLIIVKQKL 430
            N      D   L F   + +   + +L AI +     +S + P  +    KF+I+   KL
Sbjct: 697  NSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKL 756

Query: 431  PTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFSNKNKASILH 565
               G+T+   + TA       +++ N+  E  +      K + LH
Sbjct: 757  VFIGDTLTRQV-TAQDIRNKVMNSSNQLCEQLKTIVMATKMAALH 800
>sp|O93379|P53_ICTPU Cellular tumor antigen p53 (Tumor suppressor p53)
          Length = 376

 Score = 33.1 bits (74), Expect = 1.5
 Identities = 21/61 (34%), Positives = 31/61 (50%)
 Frame = +2

Query: 83  EALKKQQEQEKRDQIQKLKTQDKEDMEMAEEKIDGSKLIKTTAPLDEAVKFLQPLLTLTP 262
           EA KK +     D+I  L+ + KE  E  ++  DG +L     P D+  K+ Q LL+ T 
Sbjct: 291 EASKKSKNSSSDDEIYTLQVRGKERYEFLKKINDGLELSDVVPPADQE-KYRQKLLSKTC 349

Query: 263 R 265
           R
Sbjct: 350 R 350
>sp|O35177|CASL_MOUSE Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related
            protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor
            cell expressed developmentally down-regulated protein 9)
          Length = 833

 Score = 32.3 bits (72), Expect = 2.6
 Identities = 31/166 (18%), Positives = 75/166 (45%), Gaps = 8/166 (4%)
 Frame = +2

Query: 92   KKQQEQEKRDQIQKLKTQDKEDMEMAEEKIDGSKLIKT--TAPLDEAVKFLQPLLTLTPR 265
            K++ E+++++ ++K     +   ++   ++   +L++   T P++  +   +P  +L   
Sbjct: 636  KEEFERQQKELLEKENIMKQSKAQLEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTT 695

Query: 266  NI-----DSLCLAFKIYEKKNKILLMLKAIKSGLRIPNSLENPYFYECFIKFLIIVKQKL 430
            N      D   L F   + +   + +L AI +     +S + P  +    KF+I+   KL
Sbjct: 696  NNSVGAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKL 755

Query: 431  PTTGETVRTVIETAMKDLPHGL-DAMNKCSEITQEFSNKNKASILH 565
               G+T+    + A +D+ + + ++ N+  E  +      K + LH
Sbjct: 756  VFIGDTLTR--QVAAQDIRNKVRNSSNQLCEQLKTIVMATKMAALH 799
>sp|Q895G1|KCY_CLOTE Cytidylate kinase (CK) (Cytidine monophosphate kinase) (CMP kinase)
          Length = 226

 Score = 32.3 bits (72), Expect = 2.6
 Identities = 23/101 (22%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
 Frame = +2

Query: 206 TAPLDEAVKFLQPLLTLTPRNIDSLC---LAFKIYEKKNKILLMLKAIKSGLRIPNSLEN 376
           T  +  A+ +L     +TP N++ LC    +  +Y K +KI++  + +   +R PN   N
Sbjct: 33  TGAMYRAITYLAQNKNITPSNVEGLCNLINSISMYFKDDKIIVNGEDLSEEIRKPNVSSN 92

Query: 377 PYFYECFIK---FLIIVKQKLPTTGETVRTVIETAMKDLPH 490
              Y   ++    L+ +++ L    E V    +     +PH
Sbjct: 93  VSLYASVLEVRTLLVDIQKDLACKYEVVMDGRDIGTVVMPH 133
>sp|P08032|SPTA1_MOUSE Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin)
          Length = 2415

 Score = 32.3 bits (72), Expect = 2.6
 Identities = 28/131 (21%), Positives = 64/131 (48%), Gaps = 7/131 (5%)
 Frame = +2

Query: 386  YECFIKFLIIVKQKLPTTGETVRTVIET---AMKDLPHGLDAMNKCSEITQEFSNKNKAS 556
            +ECF + +I + +K+ T GET   + E+   A +DL      +N+  +  Q  ++  K S
Sbjct: 1223 HECFERDIIPLGEKVNTLGETAERLCESHPDATEDLQKQRTELNEAWDTLQGLTSDRKES 1282

Query: 557  I--LHQFYAW-HLGNIIRNCVQNCDYSTLESSLNRPPANGSWKDCEIVLNKLKDVY-NLK 724
            +   H+F+ +    + + N ++     T+   ++ P         EI+L + ++ + ++K
Sbjct: 1283 LNEAHKFFLFLSKASDLENWIK-----TIGGVISSPELAEDLTGTEILLERHQEHHDDIK 1337

Query: 725  EKDSVYNSLRE 757
             +D  + +L +
Sbjct: 1338 REDPTFQALED 1348
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,630,434
Number of Sequences: 369166
Number of extensions: 2200431
Number of successful extensions: 7171
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6644
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7133
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 12678799560
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00463

  1. Dr_sW_012_E21
  2. Dr_sW_002_P01
  3. Dr_sW_002_I07
  4. Dr_sW_011_E22