Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_E21
(724 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5R4J9|NARG1_PONPY NMDA receptor regulated protein 1 90 7e-18
sp|Q9BXJ9|NARG1_HUMAN NMDA receptor regulated protein 1 (N-... 89 2e-17
sp|Q80UM3|NARG1_MOUSE NMDA receptor regulated protein 1 (N-... 87 5e-17
sp|Q9DBB4|NARGL_MOUSE NMDA receptor regulated 1-like protei... 84 4e-16
sp|Q6N069|NARGL_HUMAN NMDA receptor regulated 1-like protei... 83 9e-16
sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 (HEF1) (CR... 35 0.20
sp|Q895G1|KCY_CLOTE Cytidylate kinase (CK) (Cytidine monoph... 34 0.35
sp|O93379|P53_ICTPU Cellular tumor antigen p53 (Tumor suppr... 33 0.77
sp|O35177|CASL_MOUSE Enhancer of filamentation 1 (MEF1) (CR... 32 1.7
sp|Q829L4|ECTB_STRAW Diaminobutyrate--2-oxoglutarate transa... 32 1.7
>sp|Q5R4J9|NARG1_PONPY NMDA receptor regulated protein 1
Length = 866
Score = 89.7 bits (221), Expect = 7e-18
Identities = 57/169 (33%), Positives = 89/169 (52%), Gaps = 1/169 (0%)
Frame = +2
Query: 74 AENEALKKQQEQEKRDQIQKLKTQDK-EDMEMAEEKIDGSKLIKTTAPLDEAVKFLQPLL 250
A+ E KK E+EK+ + QK K D E++ +E++ KL K PL+EA+KFL PL
Sbjct: 606 AQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLK 665
Query: 251 TLTPRNIDSLCLAFKIYEKKDKILLMLKAIKSGLRIPNSLENPYFYECFIKFLIIVKQKL 430
L I++ AF+IY +K+K LLML+++K I +S +P+ +EC I+ +
Sbjct: 666 NLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSS--HPWLHECMIRLFNTAVCES 723
Query: 431 PTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFSNKNKASILHQFYA 577
+TVRTV++ M H L + F +N S+ H+ A
Sbjct: 724 KDLSDTVRTVLKQEM----HRLFGATNPKNFNETFLKRNSDSLPHRLSA 768
>sp|Q9BXJ9|NARG1_HUMAN NMDA receptor regulated protein 1 (N-terminal acetyltransferase)
(Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen
Ga19)
Length = 866
Score = 88.6 bits (218), Expect = 2e-17
Identities = 57/169 (33%), Positives = 90/169 (53%), Gaps = 1/169 (0%)
Frame = +2
Query: 74 AENEALKKQQEQEKRDQIQKLKTQDK-EDMEMAEEKIDGSKLIKTTAPLDEAVKFLQPLL 250
A+ E KK E+EK+ + QK K D E++ +E++ KL K PL+EA+KFL PL
Sbjct: 606 AQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLK 665
Query: 251 TLTPRNIDSLCLAFKIYEKKDKILLMLKAIKSGLRIPNSLENPYFYECFIKFLIIVKQKL 430
L I++ AF+IY +K+K LLML+++K I +S +P+ +EC I+ +
Sbjct: 666 NLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSS--HPWLHECMIRLFNTAVCES 723
Query: 431 PTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFSNKNKASILHQFYA 577
+TVRTV++ M L + N + F +N S+ H+ A
Sbjct: 724 KDLSDTVRTVLKQEMNRLFGATNPKN----FNETFLKRNSDSLPHRLSA 768
>sp|Q80UM3|NARG1_MOUSE NMDA receptor regulated protein 1 (N-terminal aceyltransferase 1)
(Tubedown-1 protein)
Length = 865
Score = 87.0 bits (214), Expect = 5e-17
Identities = 59/171 (34%), Positives = 92/171 (53%), Gaps = 3/171 (1%)
Frame = +2
Query: 74 AENEALKKQQEQEKRDQIQKLKTQDK-EDMEMAEEKIDGSKLIKTTAPLDEAVKFLQPLL 250
A+ E KK E+EK+ + QK K D E++ +E++ KL K PL+EA+KFL PL
Sbjct: 606 AQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPLEEAIKFLTPLK 665
Query: 251 TLTPRNIDSLCLAFKIYEKKDKILLMLKAIKSGLRIPNSLENPYFYECFIKFL--IIVKQ 424
L I++ AF+IY +K+K LLML+++K I + +P+ +EC I+ + +
Sbjct: 666 NLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSG--HPWLHECMIRLFHSVCESK 723
Query: 425 KLPTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFSNKNKASILHQFYA 577
LP ETVRTV++ M L + N + F +N S+ H+ A
Sbjct: 724 DLP---ETVRTVLKQEMNRLFGATNPKN----FNETFLKRNSDSLPHRLSA 767
>sp|Q9DBB4|NARGL_MOUSE NMDA receptor regulated 1-like protein (NARG1-like protein)
Length = 864
Score = 84.0 bits (206), Expect = 4e-16
Identities = 61/191 (31%), Positives = 97/191 (50%), Gaps = 3/191 (1%)
Frame = +2
Query: 2 LNIENL*ISEAXXXXXXXXXXXXXAENEALKKQQEQEKRDQIQKLKTQDKEDMEMA-EEK 178
++ ENL E A+ E +K E+E++ + QK K +++E++ +E+
Sbjct: 582 IDSENLSAKEMKKMLSKQRRAQKKAKVEEERKHTERERQQKNQKKKREEEEEVTSGHKEE 641
Query: 179 IDGSKLIKTTAPLDEAVKFLQPLLTLTPRNIDSLCLAFKIYEKKDKILLMLKAIKSGLRI 358
+ KL + PL+EA+KFL PL TL +ID+ LAF+IY +K K LLML+++K I
Sbjct: 642 LIPEKLERVDNPLEEAIKFLTPLKTLAAESIDTHLLAFEIYFRKGKFLLMLQSVKRAFAI 701
Query: 359 PNSLENPYFYECFIKFLIIVK--QKLPTTGETVRTVIETAMKDLPHGLDAMNKCSEITQE 532
++ NP+ +EC IKF V LP + V V+ MK + D ++
Sbjct: 702 ESN--NPWLHECLIKFSKSVSNHSNLP---DIVSKVLAQEMKKIFVNKD----LHSFNED 752
Query: 533 FSNKNKASILH 565
F N S+ H
Sbjct: 753 FLRHNATSLQH 763
>sp|Q6N069|NARGL_HUMAN NMDA receptor regulated 1-like protein (NARG1-like protein)
Length = 864
Score = 82.8 bits (203), Expect = 9e-16
Identities = 55/189 (29%), Positives = 92/189 (48%), Gaps = 1/189 (0%)
Frame = +2
Query: 2 LNIENL*ISEAXXXXXXXXXXXXXAENEALKKQQEQEKRDQIQKLKT-QDKEDMEMAEEK 178
+N ENL E A+ E +K E+E++ + QK K +++E+ +E+
Sbjct: 582 INSENLSAKELKKMLSKQRRAQKKAKLEEERKHAERERQQKNQKKKRDEEEEEASGLKEE 641
Query: 179 IDGSKLIKTTAPLDEAVKFLQPLLTLTPRNIDSLCLAFKIYEKKDKILLMLKAIKSGLRI 358
+ KL + PL+EAVKFL PL L NID+ LAF+IY +K K LLML+++K I
Sbjct: 642 LIPEKLERVENPLEEAVKFLIPLKNLVADNIDTHLLAFEIYFRKGKFLLMLQSVKRAFAI 701
Query: 359 PNSLENPYFYECFIKFLIIVKQKLPTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFS 538
++ NP+ +EC I+F K + + ++ + + ++F
Sbjct: 702 NSN--NPWLHECLIRF-----SKSVSNHSNLPDIVSKVLSQEMQKIFVKKDLESFNEDFL 754
Query: 539 NKNKASILH 565
+N S+ H
Sbjct: 755 KRNATSLQH 763
>sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related
protein) (CAS-L) (CasL) (p105) (Protein NEDD9)
Length = 834
Score = 35.0 bits (79), Expect = 0.20
Identities = 32/165 (19%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Frame = +2
Query: 92 KKQQEQEKRDQIQKLKTQDKEDMEMAEEKIDGSKLIKT--TAPLDEAVKFLQPLLTLTPR 265
K++ E+++++ ++K + M++ ++ +L++ T P++ + +P +L
Sbjct: 637 KEEFERQQKELLEKENIMKQNKMQLEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTT 696
Query: 266 NI-----DSLCLAFKIYEKKDKILLMLKAIKSGLRIPNSLENPYFYECFIKFLIIVKQKL 430
N D L F + + + +L AI + +S + P + KF+I+ KL
Sbjct: 697 NSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKL 756
Query: 431 PTTGETVRTVIETAMKDLPHGLDAMNKCSEITQEFSNKNKASILH 565
G+T+ + TA +++ N+ E + K + LH
Sbjct: 757 VFIGDTLTRQV-TAQDIRNKVMNSSNQLCEQLKTIVMATKMAALH 800
>sp|Q895G1|KCY_CLOTE Cytidylate kinase (CK) (Cytidine monophosphate kinase) (CMP kinase)
Length = 226
Score = 34.3 bits (77), Expect = 0.35
Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Frame = +2
Query: 206 TAPLDEAVKFLQPLLTLTPRNIDSLC---LAFKIYEKKDKILLMLKAIKSGLRIPNSLEN 376
T + A+ +L +TP N++ LC + +Y K DKI++ + + +R PN N
Sbjct: 33 TGAMYRAITYLAQNKNITPSNVEGLCNLINSISMYFKDDKIIVNGEDLSEEIRKPNVSSN 92
Query: 377 PYFYECFIK---FLIIVKQKLPTTGETVRTVIETAMKDLPH 490
Y ++ L+ +++ L E V + +PH
Sbjct: 93 VSLYASVLEVRTLLVDIQKDLACKYEVVMDGRDIGTVVMPH 133
>sp|O93379|P53_ICTPU Cellular tumor antigen p53 (Tumor suppressor p53)
Length = 376
Score = 33.1 bits (74), Expect = 0.77
Identities = 21/61 (34%), Positives = 31/61 (50%)
Frame = +2
Query: 83 EALKKQQEQEKRDQIQKLKTQDKEDMEMAEEKIDGSKLIKTTAPLDEAVKFLQPLLTLTP 262
EA KK + D+I L+ + KE E ++ DG +L P D+ K+ Q LL+ T
Sbjct: 291 EASKKSKNSSSDDEIYTLQVRGKERYEFLKKINDGLELSDVVPPADQE-KYRQKLLSKTC 349
Query: 263 R 265
R
Sbjct: 350 R 350
>sp|O35177|CASL_MOUSE Enhancer of filamentation 1 (MEF1) (CRK-associated substrate-related
protein) (CAS-L) (p105) (Protein NEDD9) (Neural precursor
cell expressed developmentally down-regulated protein 9)
Length = 833
Score = 32.0 bits (71), Expect = 1.7
Identities = 31/166 (18%), Positives = 75/166 (45%), Gaps = 8/166 (4%)
Frame = +2
Query: 92 KKQQEQEKRDQIQKLKTQDKEDMEMAEEKIDGSKLIKT--TAPLDEAVKFLQPLLTLTPR 265
K++ E+++++ ++K + ++ ++ +L++ T P++ + +P +L
Sbjct: 636 KEEFERQQKELLEKENIMKQSKAQLEHHQLSQFQLLEQEITKPVENDISKWKPSQSLPTT 695
Query: 266 NI-----DSLCLAFKIYEKKDKILLMLKAIKSGLRIPNSLENPYFYECFIKFLIIVKQKL 430
N D L F + + + +L AI + +S + P + KF+I+ KL
Sbjct: 696 NNSVGAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSSAQPPRIFVAHSKFVILSAHKL 755
Query: 431 PTTGETVRTVIETAMKDLPHGL-DAMNKCSEITQEFSNKNKASILH 565
G+T+ + A +D+ + + ++ N+ E + K + LH
Sbjct: 756 VFIGDTLTR--QVAAQDIRNKVRNSSNQLCEQLKTIVMATKMAALH 799
>sp|Q829L4|ECTB_STRAW Diaminobutyrate--2-oxoglutarate transaminase
(Diaminobutyrate--2-oxoglutarate aminotransferase)
(L-2,4-diaminobutyric acid transaminase) (DABA
aminotransferase)
Length = 423
Score = 32.0 bits (71), Expect = 1.7
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Frame = +2
Query: 83 EALKKQQEQEKRDQIQKLKTQDKEDM-EMAEEKIDGSKLIKTTAPLDEAVKFLQPLLTLT 259
E L +E R + ++ +DK+ +A+ + LI+T+ P E VK L P LT+T
Sbjct: 346 ENLADVKEYRGRGLVWGIEFKDKDRAGRIAQRAFELGLLIETSGPESEVVKLL-PALTIT 404
Query: 260 PRNID 274
P +D
Sbjct: 405 PEELD 409
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,773,498
Number of Sequences: 369166
Number of extensions: 1540939
Number of successful extensions: 5199
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4787
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5161
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6462248555
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)