DrC_00444
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00444 (502 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor bet... 37 0.026 sp|P97776|ADA18_RAT ADAM 18 (A disintegrin and metalloprote... 35 0.13 sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-rela... 34 0.22 sp|O75077|ADA23_HUMAN ADAM 23 precursor (A disintegrin and ... 33 0.29 sp|Q8R4U0|STAB2_MOUSE Stabilin-2 precursor [Contains: Short... 33 0.38 sp|P34504|YMV2_CAEEL Hypothetical protein K04H4.2 precursor 33 0.38 sp|Q9R157|ADA18_MOUSE ADAM 18 precursor (A disintegrin and ... 33 0.38 sp|Q9R1V7|ADA23_MOUSE ADAM 23 precursor (A disintegrin and ... 32 0.65 sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-relat... 32 0.84 sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 31 1.9
>sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor beta binding protein 4 precursor (LTBP-4) Length = 1666 Score = 37.0 bits (84), Expect = 0.026 Identities = 27/80 (33%), Positives = 32/80 (40%), Gaps = 14/80 (17%) Frame = +1 Query: 229 CNEDKQCHSGYCVQV-AGTTKHCSK----DSRRQGLIGQG------GPC---LKDSQCSL 366 C +C G C G T C DS R I Q GPC L D CSL Sbjct: 360 CATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCYRVLHDGGCSL 419 Query: 367 RCLFQISRAKCLCTRIKKTW 426 L I++ C C+R+ K W Sbjct: 420 PILRNITKQICCCSRVGKAW 439
Score = 29.3 bits (64), Expect = 5.5
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Frame = +1
Query: 223 GICNEDKQCHSG-------YCVQVAGTTKHCSKDSRRQGLIGQGGPCLKDSQCSLRCLFQ 381
G C + +C SG C G+ HCS + + GQ GPC ++C L F
Sbjct: 873 GRCTDVDECSSGTPCGLHGQCTNTKGSF-HCSCSTGYRAPSGQPGPCADINEC-LEGDFC 930
Query: 382 ISRAKCLCT 408
+CL T
Sbjct: 931 FPHGECLNT 939
>sp|P97776|ADA18_RAT ADAM 18 (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III) (tMDC III) Length = 445 Score = 34.7 bits (78), Expect = 0.13 Identities = 29/128 (22%), Positives = 45/128 (35%), Gaps = 21/128 (16%) Frame = +1 Query: 22 CFSGVCLSMESMKFCSKETKVQNKVAERDR-------YRENNNCFSG------------Y 144 CF V E++ C + ++D +R N N S Sbjct: 240 CFEKVNSQRENLANCDSKNSYSLPCGQKDVLCGKLACFRPNKNYKSSTQSVLYSYVHGSV 299 Query: 145 CIPIKPNSEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHC--SKDSRRQG 318 C+ I P M+ KD+ +V G +C C +G C +V T C +K + G Sbjct: 300 CLSIPPGLSMRSDGKDN---AYVADGTVCGPQMYCINGSCKEVNFTGNDCNAAKKCKGNG 356 Query: 319 LIGQGGPC 342 + G C Sbjct: 357 ICNNFGHC 364
>sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-related protein 1B precursor (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT) Length = 4599 Score = 33.9 bits (76), Expect = 0.22 Identities = 34/156 (21%), Positives = 59/156 (37%), Gaps = 22/156 (14%) Frame = +1 Query: 4 CENDAQCF------SGV--CLSMESMKFCSKETKVQNKVAERDRYRENNNCFSGYCIPIK 159 C ND C +G+ C + CS + +++K ++D + C + CIP++ Sbjct: 3723 CRNDRICLQLEKICNGINDCGDNSDEEHCSGKLSLKSKPCKKDEF----TCSNRNCIPME 3778 Query: 160 ----------PNSEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKDSR 309 S+ + C K + +G C +D YC Q+ + K Sbjct: 3779 LQCDSLDDCGDGSDEQGCLKTPIEHTCENNGNPCGDD-----AYCNQIKTSVFCRCKPGF 3833 Query: 310 RQGLIGQG----GPCLKDSQCSLRCLFQISRAKCLC 405 ++ + G+ CL CS CL KC+C Sbjct: 3834 QRNMKGRECADLNECLLFGICSHHCLNTRGSYKCVC 3869
>sp|O75077|ADA23_HUMAN ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3) Length = 832 Score = 33.5 bits (75), Expect = 0.29 Identities = 31/121 (25%), Positives = 48/121 (39%) Frame = +1 Query: 10 NDAQCFSGVCLSMESMKFCSKETKVQNKVAERDRYRENNNCFSGYCIPIKPNSEMKFCAK 189 N A C G C + S F + + ++ V E D E SG C P + C + Sbjct: 536 NGAHCSDGPCCNNTSCLFQPRGYECRDAVNECD-ITEYCTGDSGQCPPNLHKQDGYACNQ 594 Query: 190 DSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKDSRRQGLIGQGGPCLKDSQCSLR 369 + G +G D QC + + AG+ K C + +G + G C KD ++ Sbjct: 595 NQ---GRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGT--EKGNCGKDGDRWIQ 649 Query: 370 C 372 C Sbjct: 650 C 650
>sp|Q8R4U0|STAB2_MOUSE Stabilin-2 precursor [Contains: Short form stabilin-2] Length = 2559 Score = 33.1 bits (74), Expect = 0.38 Identities = 31/135 (22%), Positives = 49/135 (36%), Gaps = 13/135 (9%) Frame = +1 Query: 1 ICEN----DAQCFSGVCLSMESMKFCSKETKV---------QNKVAERDRYRENNNCFSG 141 IC+N D C G C + +FC K+T + E + C G Sbjct: 805 ICDNRLDSDGSCLPGTCREGTAGRFCDKQTSACGPYMQFCHIHATCEYSNETASCVCNDG 864 Query: 142 YCIPIKPNSEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKDSRRQGL 321 Y + C+K G GG C+ + + C+Q + T C ++G Sbjct: 865 Y------EGDGTLCSKKDPCLGSTSRGG-CSPNAE-----CIQASTGTYSC---VCQRGW 909 Query: 322 IGQGGPCLKDSQCSL 366 G G C++ + C L Sbjct: 910 TGNGRDCVEINSCLL 924
Score = 28.9 bits (63), Expect = 7.1
Identities = 21/88 (23%), Positives = 32/88 (36%), Gaps = 8/88 (9%)
Frame = +1
Query: 166 SEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKDSRRQGLIGQ----- 330
S +FC+K + G CN QC G C + C + R+G G+
Sbjct: 780 SRCQFCSKPNRY------GPQCNRTCQCVHGICDNRLDSDGSCLPGTCREGTAGRFCDKQ 833
Query: 331 ---GGPCLKDSQCSLRCLFQISRAKCLC 405
GP ++ C + A C+C
Sbjct: 834 TSACGPYMQFCHIHATCEYSNETASCVC 861
>sp|P34504|YMV2_CAEEL Hypothetical protein K04H4.2 precursor Length = 967 Score = 33.1 bits (74), Expect = 0.38 Identities = 21/89 (23%), Positives = 34/89 (38%) Frame = +1 Query: 4 CENDAQCFSGVCLSMESMKFCSKETKVQNKVAERDRYRENNNCFSGYCIPIKPNSEMKFC 183 C + C +G C+ + + CS + N RD Y +C G+ + K C Sbjct: 180 CPLGSACRNGNCIPLTTSNLCS-DGSPPNNTCTRDPY----SCPKGHFC-----TAQKVC 229 Query: 184 AKDSLLAGFVGSGGICNEDKQCHSGYCVQ 270 + L +G +C D+ C G Q Sbjct: 230 CPSTALQSSIGCSTVCTIDESCPKGMTCQ 258
>sp|Q9R157|ADA18_MOUSE ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III) (tMDC III) (ADAM 27) Length = 719 Score = 33.1 bits (74), Expect = 0.38 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Frame = +1 Query: 145 CIPIKPNSEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHC--SKDSRRQG 318 C+ + P M+ +DS +V G +C C +G C +V T C +K + G Sbjct: 574 CLSVLPGLSMRSDGRDS---AYVADGTVCGPQMYCINGTCKEVNFTGNDCNATKKCKGNG 630 Query: 319 LIGQGGPC 342 + G C Sbjct: 631 ICNNFGNC 638
>sp|Q9R1V7|ADA23_MOUSE ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3) Length = 829 Score = 32.3 bits (72), Expect = 0.65 Identities = 31/121 (25%), Positives = 47/121 (38%) Frame = +1 Query: 10 NDAQCFSGVCLSMESMKFCSKETKVQNKVAERDRYRENNNCFSGYCIPIKPNSEMKFCAK 189 N A C G C + S F S+ + ++ V D E SG C P + C + Sbjct: 533 NGAHCSDGPCCNNTSCLFQSRGYECRDAVNSCD-ITEYCTGDSGQCPPNLHKQDGYSCNQ 591 Query: 190 DSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKDSRRQGLIGQGGPCLKDSQCSLR 369 + G +G D QC + + AG+ K C + +G + G C KD + Sbjct: 592 NQ---GRCYNGECKTRDNQCQYIWGTKAAGSDKFCYEKLNTEGT--EKGNCGKDGDRWIP 646 Query: 370 C 372 C Sbjct: 647 C 647
>sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91) Length = 4544 Score = 32.0 bits (71), Expect = 0.84 Identities = 37/154 (24%), Positives = 62/154 (40%), Gaps = 22/154 (14%) Frame = +1 Query: 10 NDAQCFSGVCLSMESMKFCSKETKVQNKVAERDRYRENNNCFSGYCIPIKPNSEMKF--- 180 ++ +C +G CLS + C E + + D +N +C S K N+ +F Sbjct: 2861 SEFRCANGRCLSSRQWE-CDGENDCHD---QSDEAPKNPHCTSP---EHKCNASSQFLCS 2913 Query: 181 ---CAKDSLLAGFVGSGGICNEDKQCHSGYCV--QVAGTTKHCS------KDSRRQG--L 321 C ++LL G ++++ CH C+ +++G ++ C K R G L Sbjct: 2914 SGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIGFKCRCRPGFRL 2973 Query: 322 IGQGGPCLKDSQ------CSLRCLFQISRAKCLC 405 G C + CS RC+ KCLC Sbjct: 2974 KDDGRTCADVDECSTTFPCSQRCINTHGSYKCLC 3007
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] Length = 593 Score = 30.8 bits (68), Expect = 1.9 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 6/77 (7%) Frame = +1 Query: 193 SLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSK---DSRRQGLIGQ-GGPCLKDSQC 360 +L AG V +G C + + C C+ G + C + D L GGPC D+ C Sbjct: 9 ALTAGLV-AGTRCPDGQFCPVACCLDPGGASYSCCRPLLDKWPTTLSRHLGGPCQVDAHC 67 Query: 361 SL--RCLFQISRAKCLC 405 S C+F +S C Sbjct: 68 SAGHSCIFTVSGTSSCC 84
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,282,431
Number of Sequences: 369166
Number of extensions: 1263532
Number of successful extensions: 3649
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3371
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3639
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3168768640
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
