Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_F20
(374 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8R4U0|STAB2_MOUSE Stabilin-2 precursor [Contains: Short... 36 0.031
sp|P53714|ITB2_PIG Integrin beta-2 precursor (Cell surface ... 35 0.054
sp|Q8WWQ8|STAB2_HUMAN Stabilin-2 precursor (FEEL-2 protein)... 35 0.070
sp|Q25464|FP2_MYTGA Adhesive plaque matrix protein 2 precur... 34 0.091
sp|P97776|ADA18_RAT ADAM 18 (A disintegrin and metalloprote... 34 0.12
sp|O54890|ITB3_MOUSE Integrin beta-3 precursor (Platelet me... 33 0.16
sp|Q9R157|ADA18_MOUSE ADAM 18 precursor (A disintegrin and ... 33 0.20
sp|P10968|AGI1_WHEAT Agglutinin isolectin 1 precursor (WGA1... 32 0.45
sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor bet... 32 0.45
sp|P15312|AGI_HORVU Root-specific lectin precursor 32 0.59
>sp|Q8R4U0|STAB2_MOUSE Stabilin-2 precursor [Contains: Short form stabilin-2]
Length = 2559
Score = 35.8 bits (81), Expect = 0.031
Identities = 32/134 (23%), Positives = 49/134 (36%), Gaps = 13/134 (9%)
Frame = +1
Query: 1 ICEN----DAQCFSGVCLSMGSMKFCSKETKVQNKVAE----RGRCREDNN-----CFSG 141
IC+N D C G C + +FC K+T + C N C G
Sbjct: 805 ICDNRLDSDGSCLPGTCREGTAGRFCDKQTSACGPYMQFCHIHATCEYSNETASCVCNDG 864
Query: 142 YCIPIKPNSEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKDSRRQGL 321
Y + C+K G GG C+ + + C+Q + T C ++G
Sbjct: 865 Y------EGDGTLCSKKDPCLGSTSRGG-CSPNAE-----CIQASTGTYSC---VCQRGW 909
Query: 322 IGRGGPCLKDSQCL 363
G G C++ + CL
Sbjct: 910 TGNGRDCVEINSCL 923
>sp|P53714|ITB2_PIG Integrin beta-2 precursor (Cell surface adhesion glycoproteins
LFA-1/CR3/P150,95 beta-subunit) (CD18) (Complement
receptor C3 beta-subunit)
Length = 769
Score = 35.0 bits (79), Expect = 0.054
Identities = 36/139 (25%), Positives = 56/139 (40%), Gaps = 17/139 (12%)
Frame = +1
Query: 1 ICENDAQCFSGVCLSMGSM--KFCSKETKVQNKVAERGRCREDN---------NCFSGYC 147
+C N GVC K C +T+ ++ G CR+DN +C G C
Sbjct: 458 LCGNKGSMECGVCRCDAGYIGKHCECQTQGRSSQELEGSCRKDNSSIICSGLGDCICGQC 517
Query: 148 I---PIKPNSEM--KFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKDSRR 312
+ PN ++ +FC D++ G +C +K+ G C CS +
Sbjct: 518 VCHTSDVPNKKIYGQFCECDNMNCERF-DGQVCGGEKR---GLC--------FCSTCRCQ 565
Query: 313 QGLIGRGGPCLKDSQ-CLS 366
+G G CLK +Q CL+
Sbjct: 566 EGFEGSACQCLKSTQGCLN 584
>sp|Q8WWQ8|STAB2_HUMAN Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like
laminin-type EGF-like and link domain-containing
scavenger receptor-1) (FAS1 EGF-like and X-link domain
containing adhesion molecule 2) (Hyaluronan receptor for
endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa
hyaluronan receptor for endocytosis)]
Length = 2551
Score = 34.7 bits (78), Expect = 0.070
Identities = 28/132 (21%), Positives = 44/132 (33%), Gaps = 13/132 (9%)
Frame = +1
Query: 7 ENDAQCFSGVCLSMGSMKFCSKETKVQNKVAE----RGRCREDNNCFSGYCIPIKPNSEM 174
++D C +G C + + C K+T + C N S C
Sbjct: 804 DSDGACLTGTCRDGSAGRLCDKQTSACGPYVQFCHIHATCEYSNGTASCIC--------- 854
Query: 175 KFCAKDSLLAGFVGSGGICNEDKQC---------HSGYCVQVAGTTKHCSKDSRRQGLIG 327
AG+ G G +C+E C + C++ T C +QG G
Sbjct: 855 --------KAGYEGDGTLCSEMDPCTGLTPGGCSRNAECIKTGTGTHTC---VCQQGWTG 903
Query: 328 RGGPCLKDSQCL 363
G C + + CL
Sbjct: 904 NGRDCSEINNCL 915
Score = 28.1 bits (61), Expect = 6.5
Identities = 33/130 (25%), Positives = 48/130 (36%), Gaps = 10/130 (7%)
Frame = +1
Query: 4 CENDAQCFSGVCLSMGSMKFCSKETKVQNKVAERGRCREDNNC-----FSGYCIPIKPNS 168
C+ C G C + G + S + V + ++NC S C+ +
Sbjct: 1395 CDQACSCVHGRC-NQGPLGDGSCDCDVGWRGVHCDNATTEDNCNGTCHTSANCLTNSDGT 1453
Query: 169 EMKFCAKDSLLAGFVGSGGICNEDKQCH--SGYCVQVAG---TTKHCSKDSRRQGLIGRG 333
CA AGF G+G IC C +G C A TT + + G G G
Sbjct: 1454 ASCKCA-----AGFQGNGTICTAINACEISNGGCSAKADCKRTTPGRRVCTCKAGYTGDG 1508
Query: 334 GPCLKDSQCL 363
CL+ + CL
Sbjct: 1509 IVCLEINPCL 1518
>sp|Q25464|FP2_MYTGA Adhesive plaque matrix protein 2 precursor (Foot protein 2) (MGFP2)
(MGFP-2)
Length = 473
Score = 34.3 bits (77), Expect = 0.091
Identities = 31/131 (23%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Frame = +1
Query: 4 CENDAQCFSGVCLSMGSMKFCSKETKVQNKVAERGRCREDNN-------CFSGYCIPI-- 156
C N ++ +C S C + N RGRC DN+ C GY P
Sbjct: 281 CVNKGSSYNCICKGGYSGPTCGENVCKPNPCQNRGRCYPDNSDDGFKCRCVGGYKGPTCE 340
Query: 157 -KPN-SEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKDSRRQGLIGR 330
KPN K C +GG CN + + ++ C +HC+ + +
Sbjct: 341 DKPNPCNTKPCK----------NGGKCNYNGKIYTCKCA-YGWRGRHCTDKAYKPNPCVV 389
Query: 331 GGPCLKDSQCL 363
PC +C+
Sbjct: 390 SKPCKNRGKCI 400
>sp|P97776|ADA18_RAT ADAM 18 (A disintegrin and metalloproteinase domain 18)
(Transmembrane metalloproteinase-like, disintegrin-like,
and cysteine-rich protein III) (tMDC III)
Length = 445
Score = 33.9 bits (76), Expect = 0.12
Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 145 CIPIKPNSEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHC--SKDSRRQG 318
C+ I P M+ KD+ +V G +C C +G C +V T C +K + G
Sbjct: 300 CLSIPPGLSMRSDGKDN---AYVADGTVCGPQMYCINGSCKEVNFTGNDCNAAKKCKGNG 356
Query: 319 LIGRGGPC 342
+ G C
Sbjct: 357 ICNNFGHC 364
>sp|O54890|ITB3_MOUSE Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa)
(GPIIIa) (CD61 antigen)
Length = 787
Score = 33.5 bits (75), Expect = 0.16
Identities = 25/104 (24%), Positives = 41/104 (39%), Gaps = 3/104 (2%)
Frame = +1
Query: 1 ICENDAQCFSG--VCLSMGSMKFCSKETKVQNKVAERGR-CREDNNCFSGYCIPIKPNSE 171
+C QC G VC S + +C+ T+ ++ G C NC G C+ ++P S
Sbjct: 560 MCSGHGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNGLLCSGRGNCECGSCVCVQPGSY 619
Query: 172 MKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSKD 303
C K C E K+ + G + +++C D
Sbjct: 620 GDTCEKCPTCPDACSFKKECVECKKFNRGTLHEENTCSRYCRDD 663
>sp|Q9R157|ADA18_MOUSE ADAM 18 precursor (A disintegrin and metalloproteinase domain 18)
(Transmembrane metalloproteinase-like, disintegrin-like,
and cysteine-rich protein III) (tMDC III) (ADAM 27)
Length = 719
Score = 33.1 bits (74), Expect = 0.20
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 2/68 (2%)
Frame = +1
Query: 145 CIPIKPNSEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHC--SKDSRRQG 318
C+ + P M+ +DS +V G +C C +G C +V T C +K + G
Sbjct: 574 CLSVLPGLSMRSDGRDS---AYVADGTVCGPQMYCINGTCKEVNFTGNDCNATKKCKGNG 630
Query: 319 LIGRGGPC 342
+ G C
Sbjct: 631 ICNNFGNC 638
>sp|P10968|AGI1_WHEAT Agglutinin isolectin 1 precursor (WGA1) (Isolectin A)
Length = 212
Score = 32.0 bits (71), Expect = 0.45
Identities = 27/99 (27%), Positives = 35/99 (35%), Gaps = 4/99 (4%)
Frame = +1
Query: 16 AQCFSGVCLSMGSMKFCSKETKVQNKVAERGRCREDNNCFSGYCIPIKPN----SEMKFC 183
A C + C S +C + + G CR D C S + PN S+ FC
Sbjct: 79 ATCTNNQCCSQYG--YCGFGAEYCGAGCQGGPCRADIKCGSQAGGKLCPNNLCCSQWGFC 136
Query: 184 AKDSLLAGFVGSGGICNEDKQCHSGYCVQVAGTTKHCSK 300
S G G C+ DK C +V CSK
Sbjct: 137 GLGSEFCGGGCQSGACSTDKPCGKDAGGRVCTNNYCCSK 175
>sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor beta binding protein 4 precursor
(LTBP-4)
Length = 1666
Score = 32.0 bits (71), Expect = 0.45
Identities = 25/115 (21%), Positives = 39/115 (33%), Gaps = 10/115 (8%)
Frame = +1
Query: 4 CENDAQC-FSGVCLSMGSMKFCSKETKVQNKVAERGRCREDNNCFSG-YCIP----IKPN 165
C + C G C + CS T + + G C + N C G +C P + +
Sbjct: 881 CSSGTPCGLHGQCTNTKGSFHCSCSTGYRAPSGQPGPCADINECLEGDFCFPHGECLNTD 940
Query: 166 SEMKFCAKDSLLAGFVGSGGI----CNEDKQCHSGYCVQVAGTTKHCSKDSRRQG 318
G G+ + C+E+ C SG C G+ + R G
Sbjct: 941 GSFTCTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 995
Score = 30.4 bits (67), Expect = 1.3
Identities = 17/56 (30%), Positives = 25/56 (44%), Gaps = 7/56 (12%)
Frame = +1
Query: 223 GICNEDKQCHSG-------YCVQVAGTTKHCSKDSRRQGLIGRGGPCLKDSQCLSG 369
G C + +C SG C G+ HCS + + G+ GPC ++CL G
Sbjct: 873 GRCTDVDECSSGTPCGLHGQCTNTKGSF-HCSCSTGYRAPSGQPGPCADINECLEG 927
>sp|P15312|AGI_HORVU Root-specific lectin precursor
Length = 212
Score = 31.6 bits (70), Expect = 0.59
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Frame = +1
Query: 106 GRCREDNNCFSGYCIPIKPN----SEMKFCAKDSLLAGFVGSGGICNEDKQCHSGYCVQV 273
G CR D C S + PN S+ +C S G GG C+ DK C +V
Sbjct: 107 GPCRADIKCGSQAGGKLCPNNLCCSQWGYCGLGSEFCGEGCQGGACSTDKPCGKAAGGKV 166
Query: 274 AGTTKHCSK 300
CSK
Sbjct: 167 CTNNYCCSK 175
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,217,352
Number of Sequences: 369166
Number of extensions: 946902
Number of successful extensions: 2711
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2513
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2694
length of database: 68,354,980
effective HSP length: 91
effective length of database: 51,544,095
effective search space used: 1700955135
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)