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Planaria EST Database

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00426
         (1063 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q03168|ASPP_AEDAE  Lysosomal aspartic protease precursor       372   e-103
sp|Q05744|CATD_CHICK  Cathepsin D precursor [Contains: Cathe...   350   4e-96
sp|P18242|CATD_MOUSE  Cathepsin D precursor                       334   3e-91
sp|P07339|CATD_HUMAN  Cathepsin D precursor [Contains: Cathe...   334   3e-91
sp|P24268|CATD_RAT  Cathepsin D precursor [Contains: Catheps...   332   8e-91
sp|P80209|CATD_BOVIN  Cathepsin D precursor                       331   2e-90
sp|Q9DEX3|CATD_CLUHA  Cathepsin D precursor                       328   2e-89
sp|Q9MZS8|CATD_SHEEP  Cathepsin D precursor                       323   4e-88
sp|P00795|CATD_PIG  Cathepsin D [Contains: Cathepsin D light...   318   2e-86
sp|Q805F2|CATEB_XENLA  Cathepsin E-B precursor                    300   5e-81

>sp|Q03168|ASPP_AEDAE Lysosomal aspartic protease precursor
          Length = 387

 Score =  372 bits (956), Expect = e-103
 Identities = 188/329 (57%), Positives = 230/329 (69%), Gaps = 7/329 (2%)
 Frame = +2

Query: 89   RVPLKKMESARSNIKKFNMMLSHFTK--NGKVTPFPEPLNNYMDAQYFGDITIGTPPQLF 262
            RV L K ESAR + +  +  +       N    P PEPL+NY+DAQY+G ITIGTPPQ F
Sbjct: 22   RVQLHKTESARQHFRNVDTEIKQLRLKYNAVSGPVPEPLSNYLDAQYYGAITIGTPPQSF 81

Query: 263  TVLFDTGSSNLWVPSKKCKITNIACLTHRKYDSSKSSTYVKNGTDFSIRYGTGSLSGFLS 442
             V+FDTGSSNLWVPSK+C  TNIACL H KY++ KSST+ KNGT F I+YG+GSLSG+LS
Sbjct: 82   KVVFDTGSSNLWVPSKECSFTNIACLMHNKYNAKKSSTFEKNGTAFHIQYGSGSLSGYLS 141

Query: 443  TDTVTIAGANVVNQTFGEAISEPGMTFVAAKFDGILGMAYPSISVDQVTPVFQNMVTQKL 622
            TDTV + G +V  QTF EAI+EPG+ FVAAKFDGILG+ Y SISVD V PVF NM  Q L
Sbjct: 142  TDTVGLGGVSVTKQTFAEAINEPGLVFVAAKFDGILGLGYSSISVDGVVPVFYNMFNQGL 201

Query: 623  VDAPIFSFYLNRDVNGKPGGEILFGGSDTNFYNGPFTYTPVTSKTYWQFKMDGLSMLGKT 802
            +DAP+FSFYLNRD +   GGEI+FGGSD+N Y G FTY  V  K YWQFKMD + +    
Sbjct: 202  IDAPVFSFYLNRDPSAAEGGEIIFGGSDSNKYTGDFTYLSVDRKAYWQFKMDSVKVGDTE 261

Query: 803  YCTE-CIAIADTGTSLIVGPESVIDDINSKFNGTKI-NGMTIVLCSNVAKLPVVNIQIGG 976
            +C   C AIADTGTSLI GP S +  IN    GT I NG  +V CS + KLP ++  +GG
Sbjct: 262  FCNNGCEAIADTGTSLIAGPVSEVTAINKAIGGTPIMNGEYMVDCSLIPKLPKISFVLGG 321

Query: 977  RNFPLNSTDYIMKVQD---TVCISGFTSL 1054
            ++F L   DY+++V     T+C+SGF  +
Sbjct: 322  KSFDLEGADYVLRVAQMGKTICLSGFMGI 350

>sp|Q05744|CATD_CHICK Cathepsin D precursor [Contains: Cathepsin D light chain; Cathepsin D
            heavy chain]
          Length = 398

 Score =  350 bits (898), Expect = 4e-96
 Identities = 181/344 (52%), Positives = 231/344 (67%), Gaps = 19/344 (5%)
 Frame = +2

Query: 80   ALFRVPLKKMESAR-------SNIKKFNMMLSHFTK-----NGKVTPFPEPLNNYMDAQY 223
            AL R+PL K  S R       S I   N  ++ F K          P PE L NYMDAQY
Sbjct: 20   ALIRIPLTKFTSTRRMLTEVGSEIPDMNA-ITQFLKFKLGFADLAEPTPEILKNYMDAQY 78

Query: 224  FGDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDSSKSSTYVKNGTDFS 403
            +G+I IGTPPQ FTV+FDTGSSNLWVPS  C + +IACL H KYD+SKSSTYV+NGT+F+
Sbjct: 79   YGEIGIGTPPQKFTVVFDTGSSNLWVPSVHCHLLDIACLLHHKYDASKSSTYVENGTEFA 138

Query: 404  IRYGTGSLSGFLSTDTVTIAGANVVNQTFGEAISEPGMTFVAAKFDGILGMAYPSISVDQ 583
            I YGTGSLSGFLS DTVT+    + NQ FGEA+ +PG+TF+AAKFDGILGMA+P ISVD+
Sbjct: 139  IHYGTGSLSGFLSQDTVTLGNLKIKNQIFGEAVKQPGITFIAAKFDGILGMAFPRISVDK 198

Query: 584  VTPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEILFGGSDTNFYNGPFTYTPVTSKTYW 763
            VTP F N++ QKL++  IFSFYLNRD   +PGGE+L GG+D  +Y+G F++  VT K YW
Sbjct: 199  VTPFFDNVMQQKLIEKNIFSFYLNRDPTAQPGGELLLGGTDPKYYSGDFSWVNVTRKAYW 258

Query: 764  QFKMDGLSML-GKTYCT-ECIAIADTGTSLIVGPESVIDDINSKFNGTK--INGMTIVLC 931
            Q  MD + +  G T C   C AI DTGTSLI GP   + ++ +   G K  I G  ++ C
Sbjct: 259  QVHMDSVDVANGLTLCKGGCEAIVDTGTSLITGPTKEVKELQTAI-GAKPLIKGQYVISC 317

Query: 932  SNVAKLPVVNIQIGGRNFPLNSTDYIMKVQ---DTVCISGFTSL 1054
              ++ LPVV + +GG+ + L    Y+ KV    +T+C+SGF+ L
Sbjct: 318  DKISSLPVVTLMLGGKPYQLTGEQYVFKVSAQGETICLSGFSGL 361

>sp|P18242|CATD_MOUSE Cathepsin D precursor
          Length = 410

 Score =  334 bits (856), Expect = 3e-91
 Identities = 175/352 (49%), Positives = 223/352 (63%), Gaps = 27/352 (7%)
 Frame = +2

Query: 80   ALFRVPLKKMESARSNIKKFNMMLSHFTKNGKVT------------PFPEPLNNYMDAQY 223
            A+ R+PL+K  S R  + +    +      G +T            P  E L NY+DAQY
Sbjct: 20   AIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQY 79

Query: 224  FGDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDSSKSSTYVKNGTDFS 403
            +GDI IGTPPQ FTV+FDTGSSNLWVPS  CKI +IAC  H KY+S KSSTYVKNGT F 
Sbjct: 80   YGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFD 139

Query: 404  IRYGTGSLSGFLSTDTVTI---------AGANVVNQTFGEAISEPGMTFVAAKFDGILGM 556
            I YG+GSLSG+LS DTV++          G  V  Q FGEA  +PG+ FVAAKFDGILGM
Sbjct: 140  IHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGM 199

Query: 557  AYPSISVDQVTPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEILFGGSDTNFYNGPFTY 736
             YP ISV+ V PVF N++ QKLVD  IFSFYLNRD  G+PGGE++ GG+D+ +Y+G  +Y
Sbjct: 200  GYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSY 259

Query: 737  TPVTSKTYWQFKMDGLSMLGK-TYCT-ECIAIADTGTSLIVGPESVIDDINSKFNGTK-I 907
              VT K YWQ  MD L +  + T C   C AI DTGTSL+VGP   + ++         I
Sbjct: 260  LNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLI 319

Query: 908  NGMTIVLCSNVAKLPVVNIQIGGRNFPLNSTDYIMKVQD---TVCISGFTSL 1054
             G  ++ C  V+ LP V +++GG+N+ L+   YI+KV     T+C+SGF  +
Sbjct: 320  QGEYMIPCEKVSSLPTVYLKLGGKNYELHPDKYILKVSQGGKTICLSGFMGM 371

>sp|P07339|CATD_HUMAN Cathepsin D precursor [Contains: Cathepsin D light chain; Cathepsin D
            heavy chain]
          Length = 412

 Score =  334 bits (856), Expect = 3e-91
 Identities = 173/354 (48%), Positives = 224/354 (63%), Gaps = 29/354 (8%)
 Frame = +2

Query: 80   ALFRVPLKKMESARSNIKKFNMMLSHFTKNGKVT------------PFPEPLNNYMDAQY 223
            AL R+PL K  S R  + +    +      G V+            P PE L NYMDAQY
Sbjct: 20   ALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQY 79

Query: 224  FGDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDSSKSSTYVKNGTDFS 403
            +G+I IGTPPQ FTV+FDTGSSNLWVPS  CK+ +IAC  H KY+S KSSTYVKNGT F 
Sbjct: 80   YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSSTYVKNGTSFD 139

Query: 404  IRYGTGSLSGFLSTDTVTI-----------AGANVVNQTFGEAISEPGMTFVAAKFDGIL 550
            I YG+GSLSG+LS DTV++            G  V  Q FGEA  +PG+TF+AAKFDGIL
Sbjct: 140  IHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQVFGEATKQPGITFIAAKFDGIL 199

Query: 551  GMAYPSISVDQVTPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEILFGGSDTNFYNGPF 730
            GMAYP ISV+ V PVF N++ QKLVD  IFSFYL+RD + +PGGE++ GG+D+ +Y G  
Sbjct: 200  GMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSL 259

Query: 731  TYTPVTSKTYWQFKMDGLSML-GKTYCTE-CIAIADTGTSLIVGPESVIDDINSKFNGTK 904
            +Y  VT K YWQ  +D + +  G T C E C AI DTGTSL+VGP   + ++        
Sbjct: 260  SYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVP 319

Query: 905  -INGMTIVLCSNVAKLPVVNIQIGGRNFPLNSTDYIMKVQD---TVCISGFTSL 1054
             I G  ++ C  V+ LP + +++GG+ + L+  DY +KV     T+C+SGF  +
Sbjct: 320  LIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGM 373

>sp|P24268|CATD_RAT Cathepsin D precursor [Contains: Cathepsin D 12 kDa light chain;
            Cathepsin D 9 kDa light chain; Cathepsin D 34 kDa heavy
            chain; Cathepsin D 30 kDa heavy chain]
          Length = 407

 Score =  332 bits (852), Expect = 8e-91
 Identities = 171/349 (48%), Positives = 224/349 (64%), Gaps = 24/349 (6%)
 Frame = +2

Query: 80   ALFRVPLKKMESARSNIKKFNMMLSHFTKNGKVT------------PFPEPLNNYMDAQY 223
            AL R+PL+K  S R  + +    +      G +T            P  E L NY+DAQY
Sbjct: 20   ALIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPRTKEPVSELLKNYLDAQY 79

Query: 224  FGDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDSSKSSTYVKNGTDFS 403
            +G+I IGTPPQ FTV+FDTGSSNLWVPS  CK+ +IAC  H KY+S KSSTYVKNGT F 
Sbjct: 80   YGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWVHHKYNSDKSSTYVKNGTSFD 139

Query: 404  IRYGTGSLSGFLSTDTVTI------AGANVVNQTFGEAISEPGMTFVAAKFDGILGMAYP 565
            I YG+GSLSG+LS DTV++       G  V  Q FGEA  +PG+ F+AAKFDGILGM YP
Sbjct: 140  IHYGSGSLSGYLSQDTVSVPCKSDLGGIKVEKQIFGEATKQPGVVFIAAKFDGILGMGYP 199

Query: 566  SISVDQVTPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEILFGGSDTNFYNGPFTYTPV 745
             ISV++V PVF N++ QKLV+  IFSFYLNRD  G+PGGE++ GG+D+ +Y+G  +Y  V
Sbjct: 200  FISVNKVLPVFDNLMKQKLVEKNIFSFYLNRDPTGQPGGELMLGGTDSRYYHGELSYLNV 259

Query: 746  TSKTYWQFKMDGLSMLGK-TYCT-ECIAIADTGTSLIVGPESVIDDINSKFNGTK-INGM 916
            T K YWQ  MD L +  + T C   C AI DTGTSL+VGP   + ++         I G 
Sbjct: 260  TRKAYWQVHMDQLEVGSELTLCKGGCEAIVDTGTSLLVGPVDEVKELQKAIGAVPLIQGE 319

Query: 917  TIVLCSNVAKLPVVNIQIGGRNFPLNSTDYIMKVQD---TVCISGFTSL 1054
             ++ C  V+ LP++  ++GG+N+ L+   YI+KV     T+C+SGF  +
Sbjct: 320  YMIPCEKVSSLPIITFKLGGQNYELHPEKYILKVSQAGKTICLSGFMGM 368

>sp|P80209|CATD_BOVIN Cathepsin D precursor
          Length = 390

 Score =  331 bits (848), Expect = 2e-90
 Identities = 172/351 (49%), Positives = 224/351 (63%), Gaps = 27/351 (7%)
 Frame = +2

Query: 83   LFRVPLKKMESARSNIKKFNMMLSHFTKNGKVT------------PFPEPLNNYMDAQYF 226
            + R+PL K  S R  + +    +      G ++            P PE L NYMDAQY+
Sbjct: 1    VIRIPLHKFTSIRRTMSEAAGXVXXLIAKGPISKYATGEPAVRQGPIPELLKNYMDAQYY 60

Query: 227  GDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDSSKSSTYVKNGTDFSI 406
            G+I IGTPPQ FTV+FDTGS+NLWVPS  CK+ +IAC THRKY+S KSSTYVKNGT F I
Sbjct: 61   GEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWTHRKYNSDKSSTYVKNGTTFDI 120

Query: 407  RYGTGSLSGFLSTDTVTI---------AGANVVNQTFGEAISEPGMTFVAAKFDGILGMA 559
             YG+GSLSG+LS DTV++          G  V  QTFGEAI +PG+ F+AAKFDGILGMA
Sbjct: 121  HYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPGVVFIAAKFDGILGMA 180

Query: 560  YPSISVDQVTPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEILFGGSDTNFYNGPFTYT 739
            YP ISV+ V PVF N++ QKLVD  +FSF+LNRD   +PGGE++ GG+D+ +Y G   + 
Sbjct: 181  YPRISVNNVLPVFDNLMQQKLVDKNVFSFFLNRDPKAQPGGELMLGGTDSKYYRGSLMFH 240

Query: 740  PVTSKTYWQFKMDGLSM-LGKTYCT-ECIAIADTGTSLIVGPESVIDDINSKFNGTK-IN 910
             VT + YWQ  MD L +    T C   C AI DTGTSLIVGP   + ++         I 
Sbjct: 241  NVTRQAYWQIHMDQLDVGSSLTVCKGGCEAIVDTGTSLIVGPVEEVRELQKAIGAVPLIQ 300

Query: 911  GMTIVLCSNVAKLPVVNIQIGGRNFPLNSTDYIMKV---QDTVCISGFTSL 1054
            G  ++ C  V+ LP V +++GG+++ L+  DY +KV   + TVC+SGF  +
Sbjct: 301  GEYMIPCEKVSSLPEVTVKLGGKDYALSPEDYALKVSQAETTVCLSGFMGM 351

>sp|Q9DEX3|CATD_CLUHA Cathepsin D precursor
          Length = 396

 Score =  328 bits (840), Expect = 2e-89
 Identities = 166/342 (48%), Positives = 218/342 (63%), Gaps = 17/342 (4%)
 Frame = +2

Query: 80   ALFRVPLKKMESARSNIKKFNMMLSHFTKN-----------GKVTPFPEPLNNYMDAQYF 226
            A+ R+PLKK  S R  +    + +                     P PE L NYMDAQY+
Sbjct: 18   AIVRIPLKKFRSIRRTLSDSGLNVEQLLAGTNSLQHNQGFPSSNAPTPETLKNYMDAQYY 77

Query: 227  GDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDSSKSSTYVKNGTDFSI 406
            G+I +GTP Q+FTV+FDTGSSNLW+PS  C  T+IACL H KY+ +KSSTYVKNGT+F+I
Sbjct: 78   GEIGLGTPVQMFTVVFDTGSSNLWLPSIHCSFTDIACLLHHKYNGAKSSTYVKNGTEFAI 137

Query: 407  RYGTGSLSGFLSTDTVTIAGANVVNQTFGEAISEPGMTFVAAKFDGILGMAYPSISVDQV 586
            +YG+GSLSG+LS D+ TI    V  Q FGEAI +PG+ F+AAKFDGILGMAYP ISVD V
Sbjct: 138  QYGSGSLSGYLSQDSCTIGDIVVEKQLFGEAIKQPGVAFIAAKFDGILGMAYPRISVDGV 197

Query: 587  TPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEILFGGSDTNFYNGPFTYTPVTSKTYWQ 766
             PVF  M++QK V+  +FSFYLNR+ + +PGGE+L GG+D  +Y G F Y PVT + YWQ
Sbjct: 198  PPVFDMMMSQKKVEQNVFSFYLNRNPDTEPGGELLLGGTDPKYYTGDFNYVPVTRQAYWQ 257

Query: 767  FKMDGLSMLGK-TYCTE-CIAIADTGTSLIVGPESVIDDINSKFNGTK-INGMTIVLCSN 937
              MDG+S+  + T C + C AI DTGTSLI GP + +  +         I G  ++ C  
Sbjct: 258  IHMDGMSIGSQLTLCKDGCEAIVDTGTSLITGPPAEVRALQKAIGAIPLIQGEYMIDCKK 317

Query: 938  VAKLPVVNIQIGGRNFPLNSTDYIMKVQD---TVCISGFTSL 1054
            V  LP ++  +GG+ + L    Y++K      T+C+SG   L
Sbjct: 318  VPTLPTISFNVGGKTYSLTGEQYVLKESQGGKTICLSGLMGL 359

>sp|Q9MZS8|CATD_SHEEP Cathepsin D precursor
          Length = 365

 Score =  323 bits (829), Expect = 4e-88
 Identities = 163/306 (53%), Positives = 208/306 (67%), Gaps = 15/306 (4%)
 Frame = +2

Query: 182  PFPEPLNNYMDAQYFGDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDS 361
            P PE L NYMDAQY+G+I IGTPPQ FTV+FDTGS+NLWVPS  CK+ +IAC  H KY+S
Sbjct: 41   PIPELLTNYMDAQYYGEIGIGTPPQCFTVVFDTGSANLWVPSIHCKLLDIACWVHHKYNS 100

Query: 362  SKSSTYVKNGTDFSIRYGTGSLSGFLSTDTVTI---------AGANVVNQTFGEAISEPG 514
             KSSTYVKNGT F I YG+GSLSG+LS DTV++          G  V  QTFGEAI +PG
Sbjct: 101  DKSSTYVKNGTTFDIHYGSGSLSGYLSQDTVSVPCNPSSSSPGGVTVQRQTFGEAIKQPG 160

Query: 515  MTFVAAKFDGILGMAYPSISVDQVTPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEILF 694
            + F+AAKFDGILGMAYP ISV+ V PVF N++ QKLVD  +FSF+LNRD   +PG E++ 
Sbjct: 161  VVFIAAKFDGILGMAYPRISVNNVLPVFDNLMRQKLVDKNVFSFFLNRDPKAQPGEELML 220

Query: 695  GGSDTNFYNGPFTYTPVTSKTYWQFKMDGLSM-LGKTYCT-ECIAIADTGTSLIVGPESV 868
            GG+D+ +Y G  TY  VT + YWQ  MD L +    T C   C AI DTGTSL+VGP   
Sbjct: 221  GGTDSKYYRGSLTYHNVTRQAYWQIHMDQLDVGSSLTVCKGGCEAIVDTGTSLMVGPVDE 280

Query: 869  IDDINSKFNGTK-INGMTIVLCSNVAKLPVVNIQIGGRNFPLNSTDYIMKVQD---TVCI 1036
            + +++        I G  ++ C  V+ LP V +++GG+++ L+  DY +KV     TVC+
Sbjct: 281  VRELHKAIGAVPLIQGEYMIPCEKVSSLPQVTLKLGGKDYTLSPEDYTLKVSQAGTTVCL 340

Query: 1037 SGFTSL 1054
            SGF  +
Sbjct: 341  SGFMGM 346

>sp|P00795|CATD_PIG Cathepsin D [Contains: Cathepsin D light chain; Cathepsin D heavy
            chain]
          Length = 345

 Score =  318 bits (815), Expect = 2e-86
 Identities = 164/307 (53%), Positives = 206/307 (67%), Gaps = 16/307 (5%)
 Frame = +2

Query: 182  PFPEPLNNYMDAQYFGDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDS 361
            P PE L NYMDAQY+G+I IGTPPQ FTV+FDTGSSNLWVPS  CK+ +IAC  H KY+S
Sbjct: 2    PIPEVLKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNS 61

Query: 362  SKSSTYVKNGTDFSIRYGTGSLSGFLST-DTVT---------IAGANVVNQTFGEAISEP 511
             KSSTYVKNGT F+I YG+GSLSG+LS+ DTV+         + G  V  QTFGEA  +P
Sbjct: 62   GKSSTYVKNGTTFAIHYGSGSLSGYLSSQDTVSVPCNSALSGVGGIKVERQTFGEATKQP 121

Query: 512  GMTFVAAKFDGILGMAYPSISVDQVTPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEIL 691
            G+TF+AAKFDGILGMAYP ISV+ V PVF N++ QKLVD  IFSFYLNRD   +PGGE++
Sbjct: 122  GLTFIAAKFDGILGMAYPRISVNNVVPVFDNLMQQKLVDKDIFSFYLNRDPGAQPGGELM 181

Query: 692  FGGSDTNFYNGPFTYTPVTSKTYWQFKMDGLSM-LGKTYCT-ECIAIADTGTSLIVGPES 865
             GG D+ +Y G   Y  VT K YWQ  M+ +++    T C   C AI DTGTSLIVG   
Sbjct: 182  LGGIDSKYYKGSLDYHNVTRKAYWQIHMNQVAVGSSLTLCKGGCEAIVDTGTSLIVGQPE 241

Query: 866  VIDDINSKFNGTK-INGMTIVLCSNVAKLPVVNIQIGGRNFPLNSTDYIMKVQ---DTVC 1033
             + ++         I G  ++ C  V  LP V + +GG+ + L+S +Y +KV     T+C
Sbjct: 242  EVRELGKAIGAVPLIQGEYMIPCEKVPSLPDVTVTLGGKKYKLSSENYTLKVSQAGQTIC 301

Query: 1034 ISGFTSL 1054
            +SGF  +
Sbjct: 302  LSGFMGM 308

>sp|Q805F2|CATEB_XENLA Cathepsin E-B precursor
          Length = 397

 Score =  300 bits (768), Expect = 5e-81
 Identities = 159/342 (46%), Positives = 212/342 (61%), Gaps = 14/342 (4%)
 Frame = +2

Query: 71   LVVALFRVPLKKMESARSNIKKFNMMLSHFTKNG------------KVTPFPEPLNNYMD 214
            LV  L RVPLK+ +S R   K+   +   +T+ G               P  EPL NYMD
Sbjct: 13   LVYGLIRVPLKRQKSIRKTPKEKGKLSHVWTQQGIDMVQYTDSCNNDQAP-SEPLINYMD 71

Query: 215  AQYFGDITIGTPPQLFTVLFDTGSSNLWVPSKKCKITNIACLTHRKYDSSKSSTYVKNGT 394
             QYFG+I+IGTPPQ FTV+FDTGSSNLWVPS  C   + AC  H ++    SSTY  NG 
Sbjct: 72   VQYFGEISIGTPPQNFTVIFDTGSSNLWVPSVYC--ISPACAQHNRFQPQLSSTYESNGN 129

Query: 395  DFSIRYGTGSLSGFLSTDTVTIAGANVVNQTFGEAISEPGMTFVAAKFDGILGMAYPSIS 574
            +FS++YGTGSLSG +  D+VT+ G  V NQ FGE++SEPG TFV A FDGILG+ YPSI+
Sbjct: 130  NFSLQYGTGSLSGVIGIDSVTVEGILVQNQQFGESVSEPGSTFVDASFDGILGLGYPSIA 189

Query: 575  VDQVTPVFQNMVTQKLVDAPIFSFYLNRDVNGKPGGEILFGGSDTNFYNGPFTYTPVTSK 754
            V   TPVF NM+ Q LV+ P+FS Y++RD N   GGE++FGG D + ++G   + PVT++
Sbjct: 190  VGGCTPVFDNMIAQNLVELPMFSVYMSRDPNSPVGGELVFGGFDASRFSGQLNWVPVTNQ 249

Query: 755  TYWQFKMDGLSMLGK-TYCT-ECIAIADTGTSLIVGPESVIDDINSKFNGTKINGMTIVL 928
             YWQ ++D + + G+  +C+  C AI DTGTS+I GP S I  + S    +  NG   V 
Sbjct: 250  GYWQIQLDNIQINGEVVFCSGGCQAIVDTGTSMITGPSSDIVQLQSIIGASAANGDYEVD 309

Query: 929  CSNVAKLPVVNIQIGGRNFPLNSTDYIMKVQDTVCISGFTSL 1054
            C+ + K+P +   I G  + +    Y ++  D VC SGF  L
Sbjct: 310  CTVLNKMPTMTFTINGIGYQMTPQQYTLQDDDGVCSSGFQGL 351

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 123,932,146
Number of Sequences: 369166
Number of extensions: 2655700
Number of successful extensions: 7046
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6451
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6680
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 11487183060
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

1. Dr_sW_011_E20
2. Dr_sW_013_M03
3. Dr_sW_023_D04