Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00330 (848 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q90635|DPYL2_CHICK Dihydropyrimidinase-related protein 2... 211 3e-54 sp|Q16555|DPYL2_HUMAN Dihydropyrimidinase-related protein 2... 209 6e-54 sp|P97427|DPYL1_MOUSE Dihydropyrimidinase-related protein 1... 209 6e-54 sp|O02675|DPYL2_BOVIN Dihydropyrimidinase-related protein 2... 209 6e-54 sp|P47942|DPYL2_RAT Dihydropyrimidinase-related protein 2 (... 209 1e-53 sp|O08553|DPYL2_MOUSE Dihydropyrimidinase-related protein 2... 209 1e-53 sp|Q62950|DPYL1_RAT Dihydropyrimidinase-related protein 1 (... 209 1e-53 sp|Q14194|DPYL1_HUMAN Dihydropyrimidinase-related protein 1... 204 3e-52 sp|Q63150|DPYS_RAT Dihydropyrimidinase (DHPase) (Hydantoina... 199 6e-51 sp|Q9BPU6|DPYL5_HUMAN Dihydropyrimidinase-related protein 5... 199 1e-50
>sp|Q90635|DPYL2_CHICK Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein CRMP-62) Length = 572 Score = 211 bits (536), Expect = 3e-54 Identities = 111/235 (47%), Positives = 157/235 (66%), Gaps = 2/235 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P G NG E+RMS+IW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+ Sbjct: 352 PEGTNGTEERMSIIWDKAVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVI 411 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+PD +TISA TH+ ++++NIFEGM C G +VIS GKIVLE GNL V +G+G+++P Sbjct: 412 WDPDSVKTISAKTHNISLEYNIFEGMECRGSPLVVISQGKIVLEDGNLHVTEGSGRYIPR 471 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542 PF ++V+ +++ R + + + V R YDGPV ++S + + + ++ Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520 Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701 T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|Q16555|DPYL2_HUMAN Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) Length = 572 Score = 209 bits (533), Expect = 6e-54 Identities = 111/235 (47%), Positives = 156/235 (66%), Gaps = 2/235 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P G NG E+RMSVIW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+ Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVI 411 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+PD +TISA TH+ ++++NIFEGM C G +VIS GKIVLE G L V +G+G+++P Sbjct: 412 WDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542 PF ++V+ +++ R + + + V R YDGPV ++S + + + ++ Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520 Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701 T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|P97427|DPYL1_MOUSE Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (ULIP3 protein) Length = 572 Score = 209 bits (533), Expect = 6e-54 Identities = 110/235 (46%), Positives = 156/235 (66%), Gaps = 2/235 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P GVNG+E+RM+V+W+K V +G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDAD+V+ Sbjct: 352 PEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVI 411 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+PD +TI+A +H V++NIFEGM CHG +VIS GKIV E GN+ V++G G+F+P Sbjct: 412 WDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPR 471 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542 PF +++ +V++R + S V+R YDGPV ++ + + +A S Sbjct: 472 KPFPEHLYQRVRIRSKVFGLHS--VSRGMYDGPVYEVPATPKHA--------APAPSAKS 521 Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701 + P+ R++ S+F+LSGAQIDDN P R+G R PPGG N TSL Sbjct: 522 SPSKHQPPPI-----RNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSL 571
>sp|O02675|DPYL2_BOVIN Dihydropyrimidinase-related protein 2 (DRP-2) (Neural-specific protein NSP60) Length = 572 Score = 209 bits (533), Expect = 6e-54 Identities = 111/235 (47%), Positives = 156/235 (66%), Gaps = 2/235 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P G NG E+RMSVIW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+ Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVI 411 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+PD +TISA TH+ ++++NIFEGM C G +VIS GKIVLE G L V +G+G+++P Sbjct: 412 WDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542 PF ++V+ +++ R + + + V R YDGPV ++S + + + ++ Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520 Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701 T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|P47942|DPYL2_RAT Dihydropyrimidinase-related protein 2 (DRP-2) (Turned on after division, 64 kDa protein) (TOAD-64) (Collapsin response mediator protein 2) (CRMP-2) Length = 572 Score = 209 bits (531), Expect = 1e-53 Identities = 111/235 (47%), Positives = 155/235 (65%), Gaps = 2/235 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P G NG E+RMSVIW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+ Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVI 411 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+PD +TISA TH+ +++NIFEGM C G +VIS GKIVLE G L V +G+G+++P Sbjct: 412 WDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542 PF ++V+ +++ R + + + V R YDGPV ++S + + + ++ Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520 Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701 T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|O08553|DPYL2_MOUSE Dihydropyrimidinase-related protein 2 (DRP-2) (ULIP 2 protein) Length = 572 Score = 209 bits (531), Expect = 1e-53 Identities = 111/235 (47%), Positives = 155/235 (65%), Gaps = 2/235 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P G NG E+RMSVIW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+ Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVI 411 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+PD +TISA TH+ +++NIFEGM C G +VIS GKIVLE G L V +G+G+++P Sbjct: 412 WDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542 PF ++V+ +++ R + + + V R YDGPV ++S + + + ++ Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520 Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701 T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|Q62950|DPYL1_RAT Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) Length = 572 Score = 209 bits (531), Expect = 1e-53 Identities = 109/235 (46%), Positives = 156/235 (66%), Gaps = 2/235 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P GVNG+E+RM+V+W+K V +G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDAD+V+ Sbjct: 352 PEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVI 411 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+PD +T++A +H V++NIFEGM CHG +VIS GKIV E GN+ V++G G+F+P Sbjct: 412 WDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPR 471 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542 PF +++ +V++R + S V+R YDGPV ++ + + +A S Sbjct: 472 KPFPEHLYQRVRIRSKVFGLHS--VSRGMYDGPVYEVPATPKHA--------APAPSAKS 521 Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701 + P+ R++ S+F+LSGAQIDDN P R+G R PPGG N TSL Sbjct: 522 SPSKHQPPPI-----RNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSL 571
>sp|Q14194|DPYL1_HUMAN Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) Length = 572 Score = 204 bits (519), Expect = 3e-52 Identities = 108/235 (45%), Positives = 154/235 (65%), Gaps = 2/235 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P GVNG+E+RM+V+W+K V +G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDAD+V+ Sbjct: 352 PEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVI 411 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+PD +TI+A +H V++NIFEGM CHG +VIS GKIV E GN+ V +G G+F+P Sbjct: 412 WDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPR 471 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542 F +++ +V++R++ + V+R YDGPV ++ + +A S Sbjct: 472 KAFPEHLYQRVKIRNKVFG--LQGVSRGMYDGPVYEVPATPKYAT--------PAPSAKS 521 Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701 + P+ R++ S+F+LSGAQIDDN P R+G R PPGG N TSL Sbjct: 522 SPSKHQPPPI-----RNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSL 571
>sp|Q63150|DPYS_RAT Dihydropyrimidinase (DHPase) (Hydantoinase) (DHP) Length = 519 Score = 199 bits (507), Expect = 6e-51 Identities = 98/162 (60%), Positives = 119/162 (73%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 PNGVNGVEDRMSVIWEKGV SG +D +FVAVTSTNAAK+FN+YPKKGRI +GSDAD+V+ Sbjct: 346 PNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVI 405 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+P+ RTISA THHQ V+FNIFEGM CHGV + IS G++V E G V G GKF+P Sbjct: 406 WDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFDVTAGHGKFIPR 465 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMT 488 PF+ +++ +V+ RDQ I V R PY G V+ L T Sbjct: 466 QPFAEFIYKRVKQRDQTCTPI--PVKRAPYKGEVITLKpreT 505
>sp|Q9BPU6|DPYL5_HUMAN Dihydropyrimidinase-related protein 5 (DRP-5) (ULIP6 protein) (Collapsin response mediator protein 5) (CRMP-5) (CRMP3-associated molecule) (CRAM) Length = 564 Score = 199 bits (505), Expect = 1e-50 Identities = 110/236 (46%), Positives = 149/236 (63%), Gaps = 2/236 (0%) Frame = +3 Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182 P+GV+GV+DRMSVIWE+GVV G +D +FVAVTS+NAAKL N+YP+KGRI G+DAD+V+ Sbjct: 345 PHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVV 404 Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362 W+P+ +TISAST Q DFN++E M CHGV + IS G++V E G A+GTGKF P Sbjct: 405 WDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPL 464 Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPV-VDLSKEMTNLNIDLLDQNDSSENAV 539 F + V+ K+ R++ K + V R PY G V V + + L D Sbjct: 465 RSFPDTVYKKLVQREKTLK--VRGVDRTPYLGDVAVVVHPGKKEMGTPLAD--------- 513 Query: 540 STEFSVNKRPLTSSGG-RHMQDSSFALSGAQIDDNRPARSGIRTHQPPGGNTTSLW 704 RP+T GG R + +SSF+LSG+QIDD+ P R+ R PPGG ++ +W Sbjct: 514 -----TPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 100,655,117 Number of Sequences: 369166 Number of extensions: 2028812 Number of successful extensions: 5179 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4855 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5131 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 8341863645 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)