Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_L17
(842 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q90635|DPYL2_CHICK Dihydropyrimidinase-related protein 2... 211 3e-54
sp|Q16555|DPYL2_HUMAN Dihydropyrimidinase-related protein 2... 209 6e-54
sp|P97427|DPYL1_MOUSE Dihydropyrimidinase-related protein 1... 209 6e-54
sp|O02675|DPYL2_BOVIN Dihydropyrimidinase-related protein 2... 209 6e-54
sp|P47942|DPYL2_RAT Dihydropyrimidinase-related protein 2 (... 209 1e-53
sp|O08553|DPYL2_MOUSE Dihydropyrimidinase-related protein 2... 209 1e-53
sp|Q62950|DPYL1_RAT Dihydropyrimidinase-related protein 1 (... 209 1e-53
sp|Q14194|DPYL1_HUMAN Dihydropyrimidinase-related protein 1... 204 2e-52
sp|Q63150|DPYS_RAT Dihydropyrimidinase (DHPase) (Hydantoina... 199 6e-51
sp|Q9BPU6|DPYL5_HUMAN Dihydropyrimidinase-related protein 5... 199 1e-50
>sp|Q90635|DPYL2_CHICK Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response
mediator protein CRMP-62)
Length = 572
Score = 211 bits (536), Expect = 3e-54
Identities = 111/235 (47%), Positives = 157/235 (66%), Gaps = 2/235 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P G NG E+RMS+IW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+
Sbjct: 352 PEGTNGTEERMSIIWDKAVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVI 411
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+PD +TISA TH+ ++++NIFEGM C G +VIS GKIVLE GNL V +G+G+++P
Sbjct: 412 WDPDSVKTISAKTHNISLEYNIFEGMECRGSPLVVISQGKIVLEDGNLHVTEGSGRYIPR 471
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542
PF ++V+ +++ R + + + V R YDGPV ++S + + + ++
Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520
Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701
T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL
Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|Q16555|DPYL2_HUMAN Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response
mediator protein 2) (CRMP-2) (N2A3)
Length = 572
Score = 209 bits (533), Expect = 6e-54
Identities = 111/235 (47%), Positives = 156/235 (66%), Gaps = 2/235 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P G NG E+RMSVIW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+
Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVI 411
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+PD +TISA TH+ ++++NIFEGM C G +VIS GKIVLE G L V +G+G+++P
Sbjct: 412 WDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542
PF ++V+ +++ R + + + V R YDGPV ++S + + + ++
Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520
Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701
T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL
Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|P97427|DPYL1_MOUSE Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response
mediator protein 1) (CRMP-1) (ULIP3 protein)
Length = 572
Score = 209 bits (533), Expect = 6e-54
Identities = 110/235 (46%), Positives = 156/235 (66%), Gaps = 2/235 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P GVNG+E+RM+V+W+K V +G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDAD+V+
Sbjct: 352 PEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVI 411
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+PD +TI+A +H V++NIFEGM CHG +VIS GKIV E GN+ V++G G+F+P
Sbjct: 412 WDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPR 471
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542
PF +++ +V++R + S V+R YDGPV ++ + + +A S
Sbjct: 472 KPFPEHLYQRVRIRSKVFGLHS--VSRGMYDGPVYEVPATPKHA--------APAPSAKS 521
Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701
+ P+ R++ S+F+LSGAQIDDN P R+G R PPGG N TSL
Sbjct: 522 SPSKHQPPPI-----RNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSL 571
>sp|O02675|DPYL2_BOVIN Dihydropyrimidinase-related protein 2 (DRP-2) (Neural-specific
protein NSP60)
Length = 572
Score = 209 bits (533), Expect = 6e-54
Identities = 111/235 (47%), Positives = 156/235 (66%), Gaps = 2/235 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P G NG E+RMSVIW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+
Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVI 411
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+PD +TISA TH+ ++++NIFEGM C G +VIS GKIVLE G L V +G+G+++P
Sbjct: 412 WDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542
PF ++V+ +++ R + + + V R YDGPV ++S + + + ++
Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520
Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701
T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL
Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|P47942|DPYL2_RAT Dihydropyrimidinase-related protein 2 (DRP-2) (Turned on after
division, 64 kDa protein) (TOAD-64) (Collapsin response
mediator protein 2) (CRMP-2)
Length = 572
Score = 209 bits (531), Expect = 1e-53
Identities = 111/235 (47%), Positives = 155/235 (65%), Gaps = 2/235 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P G NG E+RMSVIW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+
Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVI 411
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+PD +TISA TH+ +++NIFEGM C G +VIS GKIVLE G L V +G+G+++P
Sbjct: 412 WDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542
PF ++V+ +++ R + + + V R YDGPV ++S + + + ++
Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520
Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701
T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL
Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|O08553|DPYL2_MOUSE Dihydropyrimidinase-related protein 2 (DRP-2) (ULIP 2 protein)
Length = 572
Score = 209 bits (531), Expect = 1e-53
Identities = 111/235 (47%), Positives = 155/235 (65%), Gaps = 2/235 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P G NG E+RMSVIW+K VV+G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+
Sbjct: 352 PEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVI 411
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+PD +TISA TH+ +++NIFEGM C G +VIS GKIVLE G L V +G+G+++P
Sbjct: 412 WDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPR 471
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542
PF ++V+ +++ R + + + V R YDGPV ++S + + + ++
Sbjct: 472 KPFPDFVYKRIKARSRLAE--LRGVPRGLYDGPVCEVS---------VTPKTVTPASSAK 520
Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701
T + + P R++ S F+LSGAQIDDN P R+ R PPGG N TSL
Sbjct: 521 TSPAKQQAPPV----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571
>sp|Q62950|DPYL1_RAT Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response
mediator protein 1) (CRMP-1)
Length = 572
Score = 209 bits (531), Expect = 1e-53
Identities = 109/235 (46%), Positives = 156/235 (66%), Gaps = 2/235 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P GVNG+E+RM+V+W+K V +G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDAD+V+
Sbjct: 352 PEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVI 411
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+PD +T++A +H V++NIFEGM CHG +VIS GKIV E GN+ V++G G+F+P
Sbjct: 412 WDPDKMKTLTAKSHKSTVEYNIFEGMECHGSPLVVISQGKIVFEDGNISVSKGMGRFIPR 471
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542
PF +++ +V++R + S V+R YDGPV ++ + + +A S
Sbjct: 472 KPFPEHLYQRVRIRSKVFGLHS--VSRGMYDGPVYEVPATPKHA--------APAPSAKS 521
Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701
+ P+ R++ S+F+LSGAQIDDN P R+G R PPGG N TSL
Sbjct: 522 SPSKHQPPPI-----RNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSL 571
>sp|Q14194|DPYL1_HUMAN Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response
mediator protein 1) (CRMP-1)
Length = 572
Score = 204 bits (519), Expect = 2e-52
Identities = 108/235 (45%), Positives = 154/235 (65%), Gaps = 2/235 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P GVNG+E+RM+V+W+K V +G +D +FVAVTSTNAAK+FN+YP+KGRI +GSDAD+V+
Sbjct: 352 PEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADVVI 411
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+PD +TI+A +H V++NIFEGM CHG +VIS GKIV E GN+ V +G G+F+P
Sbjct: 412 WDPDKLKTITAKSHKSAVEYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRFIPR 471
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMTNLNIDLLDQNDSSENAVS 542
F +++ +V++R++ + V+R YDGPV ++ + +A S
Sbjct: 472 KAFPEHLYQRVKIRNKVFG--LQGVSRGMYDGPVYEVPATPKYAT--------PAPSAKS 521
Query: 543 TEFSVNKRPLTSSGGRHMQDSSFALSGAQIDDNRPARSGIRTHQPPGG--NTTSL 701
+ P+ R++ S+F+LSGAQIDDN P R+G R PPGG N TSL
Sbjct: 522 SPSKHQPPPI-----RNLHQSNFSLSGAQIDDNNPRRTGHRIVAPPGGRSNITSL 571
>sp|Q63150|DPYS_RAT Dihydropyrimidinase (DHPase) (Hydantoinase) (DHP)
Length = 519
Score = 199 bits (507), Expect = 6e-51
Identities = 98/162 (60%), Positives = 119/162 (73%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
PNGVNGVEDRMSVIWEKGV SG +D +FVAVTSTNAAK+FN+YPKKGRI +GSDAD+V+
Sbjct: 346 PNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVI 405
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+P+ RTISA THHQ V+FNIFEGM CHGV + IS G++V E G V G GKF+P
Sbjct: 406 WDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFDVTAGHGKFIPR 465
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPVVDLSKEMT 488
PF+ +++ +V+ RDQ I V R PY G V+ L T
Sbjct: 466 QPFAEFIYKRVKQRDQTCTPI--PVKRAPYKGEVITLKpreT 505
>sp|Q9BPU6|DPYL5_HUMAN Dihydropyrimidinase-related protein 5 (DRP-5) (ULIP6 protein)
(Collapsin response mediator protein 5) (CRMP-5)
(CRMP3-associated molecule) (CRAM)
Length = 564
Score = 199 bits (505), Expect = 1e-50
Identities = 110/236 (46%), Positives = 149/236 (63%), Gaps = 2/236 (0%)
Frame = +3
Query: 3 PNGVNGVEDRMSVIWEKGVVSGILDPCKFVAVTSTNAAKLFNIYPKKGRIEIGSDADLVL 182
P+GV+GV+DRMSVIWE+GVV G +D +FVAVTS+NAAKL N+YP+KGRI G+DAD+V+
Sbjct: 345 PHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVV 404
Query: 183 WNPDIKRTISASTHHQNVDFNIFEGMHCHGVAEMVISGGKIVLEVGNLRVAQGTGKFVPT 362
W+P+ +TISAST Q DFN++E M CHGV + IS G++V E G A+GTGKF P
Sbjct: 405 WDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPL 464
Query: 363 NPFSNYVFSKVQLRDQCQKNISKKVAREPYDGPV-VDLSKEMTNLNIDLLDQNDSSENAV 539
F + V+ K+ R++ K + V R PY G V V + + L D
Sbjct: 465 RSFPDTVYKKLVQREKTLK--VRGVDRTPYLGDVAVVVHPGKKEMGTPLAD--------- 513
Query: 540 STEFSVNKRPLTSSGG-RHMQDSSFALSGAQIDDNRPARSGIRTHQPPGGNTTSLW 704
RP+T GG R + +SSF+LSG+QIDD+ P R+ R PPGG ++ +W
Sbjct: 514 -----TPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW 564
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,732,962
Number of Sequences: 369166
Number of extensions: 2009976
Number of successful extensions: 5058
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4741
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5010
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8245425915
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)