Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00309 (784 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q99611|SPS2_HUMAN Selenide, water dikinase 2 (Selenophos... 204 2e-52 sp|P97364|SPS2_MOUSE Selenide, water dikinase 2 (Selenophos... 202 6e-52 sp|P49903|SPS1_HUMAN Selenide, water dikinase 1 (Selenophos... 198 2e-50 sp|Q8BH69|SPS1_MOUSE Selenide, water dikinase 1 (Selenophos... 198 2e-50 sp|O18373|SPS1_DROME Selenide, water dikinase (Selenophosph... 191 2e-48 sp|Q94497|SELD_DICDI Selenide, water dikinase (Selenophosph... 187 2e-47 sp|O62461|SELD_CAEEL Probable selenide, water dikinase (Sel... 178 2e-44 sp|Q9VKY8|SPS2_DROME Selenide, water dikinase 2 (Selenophos... 171 2e-42 sp|Q8TVM0|SELD_METKA Selenide, water dikinase (Selenophosph... 109 7e-24 sp|P60819|SELD_METJA Selenide, water dikinase (Selenophosph... 106 6e-23
>sp|Q99611|SPS2_HUMAN Selenide, water dikinase 2 (Selenophosphate synthetase 2) (Selenium donor protein 2) Length = 448 Score = 204 bits (520), Expect = 2e-52 Identities = 109/208 (52%), Positives = 141/208 (67%), Gaps = 7/208 (3%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 VTGGQTVVNPW+IIGGVAT VC NE IMP++A +GDVLVLTKPLGTQVAVNA+QW+ D Sbjct: 210 VTGGQTVVNPWIIIGGVATVVCQPNEFIMPDSAVVGDVLVLTKPLGTQVAVNAHQWL-DN 268 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATN 360 R+ K+K +++ +E++ ++ A MATLN+ A LMH + A A TD+TGFGILGH+ N Sbjct: 269 PERWNKVKMVVSREEVELAYQEAMFNMATLNRTAAGLMHTFNAHAATDITGFGILGHSQN 328 Query: 361 LVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKKENAEKFV 540 L + Q V F+I LP + A+ G L +G S ETSGGL I L +E A +F Sbjct: 329 LAKQQRNEVSFVIHNLPIIAKMAAVSKA-SGRFGLLQGTSAETSGGLLICLpreQAARFC 387 Query: 541 SEMPSN-------AWIIGRVESGSRCAK 603 SE+ S+ AWI+G VE G+R A+ Sbjct: 388 SEIKSSKYGEGHQAWIVGIVEKGNRTAR 415
>sp|P97364|SPS2_MOUSE Selenide, water dikinase 2 (Selenophosphate synthetase 2) (Selenium donor protein 2) Length = 452 Score = 202 bits (515), Expect = 6e-52 Identities = 109/208 (52%), Positives = 140/208 (67%), Gaps = 7/208 (3%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 VTGGQTVVNPW+IIGGVAT VC NE IMP++A +GDVLVLTKPLGTQVA NA+QW+ D Sbjct: 213 VTGGQTVVNPWIIIGGVATVVCQQNEFIMPDSAVVGDVLVLTKPLGTQVAANAHQWL-DN 271 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATN 360 ++ KIK +++ +E++ ++ A MATLN+ A LMH + A A TD+TGFGILGH+ N Sbjct: 272 PEKWNKIKMVVSREEVELAYQEAMFNMATLNRTAAGLMHTFNAHAATDITGFGILGHSQN 331 Query: 361 LVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKKENAEKFV 540 L + Q V F+I LP + AI G L +G S ETSGGL I L +E A +F Sbjct: 332 LAKQQKNEVSFVIHNLPIIAKMAAISKA-SGRFGLLQGTSAETSGGLLICLpreQAARFC 390 Query: 541 SEMPSN-------AWIIGRVESGSRCAK 603 SE+ S+ AWI+G VE G+R A+ Sbjct: 391 SEIKSSKYGEGHQAWIVGIVEKGNRTAR 418
>sp|P49903|SPS1_HUMAN Selenide, water dikinase 1 (Selenophosphate synthetase 1) (Selenium donor protein 1) Length = 392 Score = 198 bits (503), Expect = 2e-50 Identities = 105/208 (50%), Positives = 134/208 (64%), Gaps = 7/208 (3%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 VTGGQTV+NPW+++GGVAT VC NE IMP+NA GDVLVLTKPLGTQVAV +QW+ D Sbjct: 159 VTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWL-DI 217 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATN 360 ++ KIK ++T ++++ ++ A MA LN+ A LMH + A A TD+TGFGILGHA N Sbjct: 218 PEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQN 277 Query: 361 LVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKKENAEKFV 540 L + Q V F+I LP L A+ L G PETSGGL I L +E A +F Sbjct: 278 LAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLpreQAARFC 337 Query: 541 SEMPS-------NAWIIGRVESGSRCAK 603 +E+ S AWIIG VE G+R A+ Sbjct: 338 AEIKSPKYGEGHQAWIIGIVEKGNRTAR 365
>sp|Q8BH69|SPS1_MOUSE Selenide, water dikinase 1 (Selenophosphate synthetase 1) (Selenium donor protein 1) Length = 392 Score = 198 bits (503), Expect = 2e-50 Identities = 105/208 (50%), Positives = 134/208 (64%), Gaps = 7/208 (3%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 VTGGQTV+NPW+++GGVAT VC NE IMP+NA GDVLVLTKPLGTQVAV +QW+ D Sbjct: 159 VTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWL-DI 217 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATN 360 ++ KIK ++T ++++ ++ A MA LN+ A LMH + A A TD+TGFGILGHA N Sbjct: 218 PEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQN 277 Query: 361 LVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKKENAEKFV 540 L + Q V F+I LP L A+ L G PETSGGL I L +E A +F Sbjct: 278 LAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLpreQAARFC 337 Query: 541 SEMPS-------NAWIIGRVESGSRCAK 603 +E+ S AWIIG VE G+R A+ Sbjct: 338 AEIKSPKYGEGHQAWIIGIVEKGNRTAR 365
>sp|O18373|SPS1_DROME Selenide, water dikinase (Selenophosphate synthetase) (Selenium donor protein) (Patufet protein) (dSelD) Length = 398 Score = 191 bits (485), Expect = 2e-48 Identities = 98/205 (47%), Positives = 133/205 (64%), Gaps = 4/205 (1%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 VTGGQ+VVNPW IGGVA+ +C NE I+P+NA +GDVLVLTKPLGTQVAVNA+QW+ D+ Sbjct: 181 VTGGQSVVNPWCTIGGVASTICQPNEYIVPDNAVVGDVLVLTKPLGTQVAVNAHQWI-DQ 239 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATN 360 R+ +IK +++++++ + A MA LN+ A+LMHKY A TD+TGFG+LGHA Sbjct: 240 PERWNRIKLVVSEEDVRKAYHRAMNSMARLNRVAARLMHKYNAHGATDITGFGLLGHAQT 299 Query: 361 LVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKKENAEKFV 540 L Q V F+I LP + A+ +L +G S ETSGGL I L +E A + Sbjct: 300 LAAHQKKDVSFVIHNLPVIAKMAAVAKACGNMFQLLQGHSAETSGGLLICLpreQAAAYC 359 Query: 541 SEMPS----NAWIIGRVESGSRCAK 603 ++ AWIIG VE G++ A+ Sbjct: 360 KDIEKQEGYQAWIIGIVEKGNKTAR 384
>sp|Q94497|SELD_DICDI Selenide, water dikinase (Selenophosphate synthetase) (Selenium donor protein) Length = 370 Score = 187 bits (476), Expect = 2e-47 Identities = 104/197 (52%), Positives = 128/197 (64%), Gaps = 4/197 (2%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 V+GGQTV NPW I+GGVAT++ NE I P NA GDVLVLT PLGTQ VN +QW++ K Sbjct: 173 VSGGQTVKNPWPIVGGVATSILKTNEFIKPVNAVPGDVLVLTNPLGTQFCVNFHQWLS-K 231 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATN 360 R EKI I KE + +F AT MA LN+ GA+LM Y A A TDVTGFGILGH+TN Sbjct: 232 PKRGEKINTITNAKECEQVFNYATLSMAKLNRVGAKLMKNYNAHAATDVTGFGILGHSTN 291 Query: 361 LVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKKENAEKFV 540 L + QL + F I LP +++ ++D L+ KL +G S ETSGGL I + +ENAE F Sbjct: 292 LAQNQLLPIRFEIHTLPIIKHMKKLEDHLNHPFKLLKGTSAETSGGLLISMSRENAEAFC 351 Query: 541 SEM----PSNAWIIGRV 579 E+ AWIIG V Sbjct: 352 KEIYEIEKQPAWIIGDV 368
>sp|O62461|SELD_CAEEL Probable selenide, water dikinase (Selenophosphate synthetase) (Selenium donor protein) Length = 378 Score = 178 bits (451), Expect = 2e-44 Identities = 95/201 (47%), Positives = 134/201 (66%), Gaps = 8/201 (3%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 + GGQTV PWL++GGVAT+V +EII + A GDVL+LTKP+G QVAVN+Y+W+ K Sbjct: 155 IRGGQTVRCPWLLLGGVATSVAHESEIIKVDQAVPGDVLILTKPIGGQVAVNSYEWIKKK 214 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATN 360 + E++ L +I+ F+ +QM+ LN+ A+L+HKY A + TDVTGFG+LGHA N Sbjct: 215 NGKIEELN--LEIPKIEKAFKQVCEQMSRLNRNAAKLLHKYDAHSSTDVTGFGLLGHAEN 272 Query: 361 LVECQLASVDFLIEKLPCLQYTMAIDDVL----DGAMKLRRGFSPETSGGLFIVLKKENA 528 L Q ++F+IEKLP ++Y I D + KL +G S ETSGGL I + +ENA Sbjct: 273 LARVQKQPMEFIIEKLPIIEYMDEIADKMIAKGGEGFKLYQGTSAETSGGLLIAMSEENA 332 Query: 529 EKFVSEMPS----NAWIIGRV 579 +K+++E+ S AWIIG+V Sbjct: 333 KKYIAELSSLDNAPAWIIGKV 353
>sp|Q9VKY8|SPS2_DROME Selenide, water dikinase 2 (Selenophosphate synthetase 2) (Selenium donor protein 2) (Dsps2) Length = 370 Score = 171 bits (433), Expect = 2e-42 Identities = 86/175 (49%), Positives = 115/175 (65%) Frame = +1 Query: 13 QTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDKTPRY 192 Q +NPW IIGG+AT+VC EII+P+NA+ GDVLVLTKPLG Q+A++A+ W ++T +Y Sbjct: 155 QLKINPWCIIGGIATSVCRSEEIILPSNAQPGDVLVLTKPLGGQMAMDAHLWQLNQTEKY 214 Query: 193 EKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATNLVEC 372 +K+ +D +I FE A K M LN+ A LMHKY A TD+TGFG+LGHA NL + Sbjct: 215 KKLLSECSDADIKETFEIAVKSMTYLNKNAALLMHKYQAHCATDITGFGLLGHANNLAQF 274 Query: 373 QLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKKENAEKF 537 Q V F I KLP ++ + ++ + K R G S ETSGGL I L + A+KF Sbjct: 275 QKEKVLFQINKLPIIKNVLKFSTLVGQSTKFRSGRSVETSGGLLICLPADAADKF 329
>sp|Q8TVM0|SELD_METKA Selenide, water dikinase (Selenophosphate synthetase) (Selenium donor protein) Length = 334 Score = 109 bits (273), Expect = 7e-24 Identities = 74/200 (37%), Positives = 101/200 (50%), Gaps = 3/200 (1%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 + GG T++NPW I+GG T + AE GDVL LTKPLGTQ A+ A + D Sbjct: 132 IVGGHTIMNPWPILGGCVTGFA--ERYVTVGGAEPGDVLYLTKPLGTQPAMAALRLPEDV 189 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHKYAAKACTDVTGFGILGHATN 360 K LTD E++ + A + M + A+ + A TDVTGFG+ GHA Sbjct: 190 R------KQFLTDSELEEAVDLAVEVMTEPLKDAAEAALEVGVHAMTDVTGFGLKGHAGE 243 Query: 361 LVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKKENAEKFV 540 + E + V +IE+LP + T + L L RG S ET+GGL + + +E+AE Sbjct: 244 MAEA--SGVRVVIERLPVIPGTTELSRAL--GYGLERGESAETAGGLLVAVPEEHAEDLE 299 Query: 541 SEMP-SNAWI--IGRVESGS 591 + W IGRVE GS Sbjct: 300 DAFERRDVWYRRIGRVEEGS 319
>sp|P60819|SELD_METJA Selenide, water dikinase (Selenophosphate synthetase) (Selenium donor protein) Length = 349 Score = 106 bits (265), Expect = 6e-23 Identities = 68/203 (33%), Positives = 105/203 (51%), Gaps = 10/203 (4%) Frame = +1 Query: 1 VTGGQTVVNPWLIIGGVATAVCPINEIIMPNNAEIGDVLVLTKPLGTQVAVNAYQWMNDK 180 + GG T++NPW +IGG T V E++ ++GDVL+LTKPLGTQ A+ + Sbjct: 137 IVGGHTILNPWPLIGGAVTGVGREEEVLTKAGVKVGDVLILTKPLGTQTAMAL-----SR 191 Query: 181 TPRYEKIKHILTDKEIDSLFETATKQMATLNQKGAQLMHK-------YAAKACTDVTGFG 339 P K +T++E D + A + M T N+ + + K A A TD+TGFG Sbjct: 192 IPEEFKDLISITEEERDYIINKAIEIMTTSNRYALKALRKAEERVGDKIANALTDITGFG 251 Query: 340 ILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKLRRGFSPETSGGLFIVLKK 519 ILGH+ + + ++ I LPC++ T + + A L G+ ET+GGL I K+ Sbjct: 252 ILGHSNEMAKNSNVLIE--INLLPCIKRTPELSRLFGHA--LLDGYGAETAGGLLISAKE 307 Query: 520 ENAEKFVSEMPS---NAWIIGRV 579 E + + E+ A+ +GRV Sbjct: 308 EYKDNLIDELEKAKCYAFEVGRV 330
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 94,929,111 Number of Sequences: 369166 Number of extensions: 2007577 Number of successful extensions: 5989 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5792 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5926 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 7357347200 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)