Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_M01
(689 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99611|SPS2_HUMAN Selenide, water dikinase 2 (Selenophos... 152 8e-37
sp|P97364|SPS2_MOUSE Selenide, water dikinase 2 (Selenophos... 150 3e-36
sp|Q94497|SELD_DICDI Selenide, water dikinase (Selenophosph... 147 3e-35
sp|P49903|SPS1_HUMAN Selenide, water dikinase 1 (Selenophos... 146 4e-35
sp|Q8BH69|SPS1_MOUSE Selenide, water dikinase 1 (Selenophos... 146 4e-35
sp|O62461|SELD_CAEEL Probable selenide, water dikinase (Sel... 145 8e-35
sp|O18373|SPS1_DROME Selenide, water dikinase (Selenophosph... 145 1e-34
sp|Q9VKY8|SPS2_DROME Selenide, water dikinase 2 (Selenophos... 133 5e-31
sp|Q8TVM0|SELD_METKA Selenide, water dikinase (Selenophosph... 90 6e-18
sp|P60819|SELD_METJA Selenide, water dikinase (Selenophosph... 80 7e-15
>sp|Q99611|SPS2_HUMAN Selenide, water dikinase 2 (Selenophosphate synthetase 2) (Selenium
donor protein 2)
Length = 448
Score = 152 bits (384), Expect = 8e-37
Identities = 84/176 (47%), Positives = 113/176 (64%), Gaps = 7/176 (3%)
Frame = +2
Query: 2 AEIGDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQ 181
A +GDVLVLTKPLGTQVAVNA+QW+ D R+ K+K +++ +E++ ++ A MATLN+
Sbjct: 242 AVVGDVLVLTKPLGTQVAVNAHQWL-DNPERWNKVKMVVSREEVELAYQEAMFNMATLNR 300
Query: 182 KGAQLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGA 361
A LMH + A A TD+TGFGILGH+ NL + Q V F+I LP + A+ G
Sbjct: 301 TAAGLMHTFNAHAATDITGFGILGHSQNLAKQQRNEVSFVIHNLPIIAKMAAVSKA-SGR 359
Query: 362 MKLRRGFSPETSGGLFIVLKKENAEKFVSEMPSN-------AWIIGRVESGSRCAK 508
L +G S ETSGGL I L +E A +F SE+ S+ AWI+G VE G+R A+
Sbjct: 360 FGLLQGTSAETSGGLLICLpreQAARFCSEIKSSKYGEGHQAWIVGIVEKGNRTAR 415
>sp|P97364|SPS2_MOUSE Selenide, water dikinase 2 (Selenophosphate synthetase 2) (Selenium
donor protein 2)
Length = 452
Score = 150 bits (379), Expect = 3e-36
Identities = 84/176 (47%), Positives = 112/176 (63%), Gaps = 7/176 (3%)
Frame = +2
Query: 2 AEIGDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQ 181
A +GDVLVLTKPLGTQVA NA+QW+ D ++ KIK +++ +E++ ++ A MATLN+
Sbjct: 245 AVVGDVLVLTKPLGTQVAANAHQWL-DNPEKWNKIKMVVSREEVELAYQEAMFNMATLNR 303
Query: 182 KGAQLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGA 361
A LMH + A A TD+TGFGILGH+ NL + Q V F+I LP + AI G
Sbjct: 304 TAAGLMHTFNAHAATDITGFGILGHSQNLAKQQKNEVSFVIHNLPIIAKMAAISKA-SGR 362
Query: 362 MKLRRGFSPETSGGLFIVLKKENAEKFVSEMPSN-------AWIIGRVESGSRCAK 508
L +G S ETSGGL I L +E A +F SE+ S+ AWI+G VE G+R A+
Sbjct: 363 FGLLQGTSAETSGGLLICLpreQAARFCSEIKSSKYGEGHQAWIVGIVEKGNRTAR 418
>sp|Q94497|SELD_DICDI Selenide, water dikinase (Selenophosphate synthetase) (Selenium
donor protein)
Length = 370
Score = 147 bits (370), Expect = 3e-35
Identities = 83/162 (51%), Positives = 103/162 (63%), Gaps = 4/162 (2%)
Frame = +2
Query: 11 GDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQKGA 190
GDVLVLT PLGTQ VN +QW++ K R EKI I KE + +F AT MA LN+ GA
Sbjct: 208 GDVLVLTNPLGTQFCVNFHQWLS-KPKRGEKINTITNAKECEQVFNYATLSMAKLNRVGA 266
Query: 191 QLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKL 370
+LM Y A A TDVTGFGILGH+TNL + QL + F I LP +++ ++D L+ KL
Sbjct: 267 KLMKNYNAHAATDVTGFGILGHSTNLAQNQLLPIRFEIHTLPIIKHMKKLEDHLNHPFKL 326
Query: 371 RRGFSPETSGGLFIVLKKENAEKFVSEM----PSNAWIIGRV 484
+G S ETSGGL I + +ENAE F E+ AWIIG V
Sbjct: 327 LKGTSAETSGGLLISMSRENAEAFCKEIYEIEKQPAWIIGDV 368
>sp|P49903|SPS1_HUMAN Selenide, water dikinase 1 (Selenophosphate synthetase 1) (Selenium
donor protein 1)
Length = 392
Score = 146 bits (369), Expect = 4e-35
Identities = 81/173 (46%), Positives = 105/173 (60%), Gaps = 7/173 (4%)
Frame = +2
Query: 11 GDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQKGA 190
GDVLVLTKPLGTQVAV +QW+ D ++ KIK ++T ++++ ++ A MA LN+ A
Sbjct: 194 GDVLVLTKPLGTQVAVAVHQWL-DIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAA 252
Query: 191 QLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKL 370
LMH + A A TD+TGFGILGHA NL + Q V F+I LP L A+ L
Sbjct: 253 GLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGL 312
Query: 371 RRGFSPETSGGLFIVLKKENAEKFVSEMPS-------NAWIIGRVESGSRCAK 508
G PETSGGL I L +E A +F +E+ S AWIIG VE G+R A+
Sbjct: 313 MHGTCPETSGGLLICLpreQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTAR 365
>sp|Q8BH69|SPS1_MOUSE Selenide, water dikinase 1 (Selenophosphate synthetase 1) (Selenium
donor protein 1)
Length = 392
Score = 146 bits (369), Expect = 4e-35
Identities = 81/173 (46%), Positives = 105/173 (60%), Gaps = 7/173 (4%)
Frame = +2
Query: 11 GDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQKGA 190
GDVLVLTKPLGTQVAV +QW+ D ++ KIK ++T ++++ ++ A MA LN+ A
Sbjct: 194 GDVLVLTKPLGTQVAVAVHQWL-DIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAA 252
Query: 191 QLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGAMKL 370
LMH + A A TD+TGFGILGHA NL + Q V F+I LP L A+ L
Sbjct: 253 GLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGL 312
Query: 371 RRGFSPETSGGLFIVLKKENAEKFVSEMPS-------NAWIIGRVESGSRCAK 508
G PETSGGL I L +E A +F +E+ S AWIIG VE G+R A+
Sbjct: 313 MHGTCPETSGGLLICLpreQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTAR 365
>sp|O62461|SELD_CAEEL Probable selenide, water dikinase (Selenophosphate synthetase)
(Selenium donor protein)
Length = 378
Score = 145 bits (367), Expect = 8e-35
Identities = 77/166 (46%), Positives = 110/166 (66%), Gaps = 8/166 (4%)
Frame = +2
Query: 11 GDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQKGA 190
GDVL+LTKP+G QVAVN+Y+W+ K + E++ L +I+ F+ +QM+ LN+ A
Sbjct: 190 GDVLILTKPIGGQVAVNSYEWIKKKNGKIEELN--LEIPKIEKAFKQVCEQMSRLNRNAA 247
Query: 191 QLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVL----DG 358
+L+HKY A + TDVTGFG+LGHA NL Q ++F+IEKLP ++Y I D +
Sbjct: 248 KLLHKYDAHSSTDVTGFGLLGHAENLARVQKQPMEFIIEKLPIIEYMDEIADKMIAKGGE 307
Query: 359 AMKLRRGFSPETSGGLFIVLKKENAEKFVSEMPS----NAWIIGRV 484
KL +G S ETSGGL I + +ENA+K+++E+ S AWIIG+V
Sbjct: 308 GFKLYQGTSAETSGGLLIAMSEENAKKYIAELSSLDNAPAWIIGKV 353
>sp|O18373|SPS1_DROME Selenide, water dikinase (Selenophosphate synthetase) (Selenium
donor protein) (Patufet protein) (dSelD)
Length = 398
Score = 145 bits (366), Expect = 1e-34
Identities = 77/173 (44%), Positives = 107/173 (61%), Gaps = 4/173 (2%)
Frame = +2
Query: 2 AEIGDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQ 181
A +GDVLVLTKPLGTQVAVNA+QW+ D+ R+ +IK +++++++ + A MA LN+
Sbjct: 213 AVVGDVLVLTKPLGTQVAVNAHQWI-DQPERWNRIKLVVSEEDVRKAYHRAMNSMARLNR 271
Query: 182 KGAQLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGA 361
A+LMHKY A TD+TGFG+LGHA L Q V F+I LP + A+
Sbjct: 272 VAARLMHKYNAHGATDITGFGLLGHAQTLAAHQKKDVSFVIHNLPVIAKMAAVAKACGNM 331
Query: 362 MKLRRGFSPETSGGLFIVLKKENAEKFVSEMPS----NAWIIGRVESGSRCAK 508
+L +G S ETSGGL I L +E A + ++ AWIIG VE G++ A+
Sbjct: 332 FQLLQGHSAETSGGLLICLpreQAAAYCKDIEKQEGYQAWIIGIVEKGNKTAR 384
>sp|Q9VKY8|SPS2_DROME Selenide, water dikinase 2 (Selenophosphate synthetase 2) (Selenium
donor protein 2) (Dsps2)
Length = 370
Score = 133 bits (334), Expect = 5e-31
Identities = 69/147 (46%), Positives = 93/147 (63%)
Frame = +2
Query: 2 AEIGDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQ 181
A+ GDVLVLTKPLG Q+A++A+ W ++T +Y+K+ +D +I FE A K M LN+
Sbjct: 183 AQPGDVLVLTKPLGGQMAMDAHLWQLNQTEKYKKLLSECSDADIKETFEIAVKSMTYLNK 242
Query: 182 KGAQLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGA 361
A LMHKY A TD+TGFG+LGHA NL + Q V F I KLP ++ + ++ +
Sbjct: 243 NAALLMHKYQAHCATDITGFGLLGHANNLAQFQKEKVLFQINKLPIIKNVLKFSTLVGQS 302
Query: 362 MKLRRGFSPETSGGLFIVLKKENAEKF 442
K R G S ETSGGL I L + A+KF
Sbjct: 303 TKFRSGRSVETSGGLLICLPADAADKF 329
>sp|Q8TVM0|SELD_METKA Selenide, water dikinase (Selenophosphate synthetase) (Selenium
donor protein)
Length = 334
Score = 89.7 bits (221), Expect = 6e-18
Identities = 64/168 (38%), Positives = 86/168 (51%), Gaps = 3/168 (1%)
Frame = +2
Query: 2 AEIGDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQ 181
AE GDVL LTKPLGTQ A+ A + D K LTD E++ + A + M +
Sbjct: 162 AEPGDVLYLTKPLGTQPAMAALRLPEDVR------KQFLTDSELEEAVDLAVEVMTEPLK 215
Query: 182 KGAQLMHKYAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAIDDVLDGA 361
A+ + A TDVTGFG+ GHA + E + V +IE+LP + T + L
Sbjct: 216 DAAEAALEVGVHAMTDVTGFGLKGHAGEMAEA--SGVRVVIERLPVIPGTTELSRAL--G 271
Query: 362 MKLRRGFSPETSGGLFIVLKKENAEKFVSEMP-SNAWI--IGRVESGS 496
L RG S ET+GGL + + +E+AE + W IGRVE GS
Sbjct: 272 YGLERGESAETAGGLLVAVPEEHAEDLEDAFERRDVWYRRIGRVEEGS 319
>sp|P60819|SELD_METJA Selenide, water dikinase (Selenophosphate synthetase) (Selenium
donor protein)
Length = 349
Score = 79.7 bits (195), Expect = 7e-15
Identities = 56/170 (32%), Positives = 87/170 (51%), Gaps = 10/170 (5%)
Frame = +2
Query: 5 EIGDVLVLTKPLGTQVAVNAYQWMNDKTPRYEKIKHILTDKEIDSLFETATKQMATLNQK 184
++GDVL+LTKPLGTQ A+ + P K +T++E D + A + M T N+
Sbjct: 170 KVGDVLILTKPLGTQTAMAL-----SRIPEEFKDLISITEEERDYIINKAIEIMTTSNRY 224
Query: 185 GAQLMHK-------YAAKACTDVTGFGILGHATNLVECQLASVDFLIEKLPCLQYTMAID 343
+ + K A A TD+TGFGILGH+ + + ++ I LPC++ T +
Sbjct: 225 ALKALRKAEERVGDKIANALTDITGFGILGHSNEMAKNSNVLIE--INLLPCIKRTPELS 282
Query: 344 DVLDGAMKLRRGFSPETSGGLFIVLKKENAEKFVSEMPS---NAWIIGRV 484
+ A L G+ ET+GGL I K+E + + E+ A+ +GRV
Sbjct: 283 RLFGHA--LLDGYGAETAGGLLISAKEEYKDNLIDELEKAKCYAFEVGRV 330
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,496,193
Number of Sequences: 369166
Number of extensions: 1713134
Number of successful extensions: 4688
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4519
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4632
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5927776870
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)