Planaria EST Database


DrC_00287

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00287
         (1130 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q8VEK6|ING3_MOUSE  Inhibitor of growth protein 3 (p47ING3...    65   5e-10
sp|Q9NXR8|ING3_HUMAN  Inhibitor of growth protein 3 (p47ING3...    63   1e-09
sp|Q9UK53|ING1_HUMAN  Inhibitor of growth protein 1                56   2e-07
sp|Q9QXV3|ING1_MOUSE  Inhibitor of growth protein 1                54   8e-07
sp|P38806|YNG2_YEAST  ING1 homolog 2 (ESA1-associated factor 4)    52   4e-06
sp|Q9H160|ING2_HUMAN  Inhibitor of growth protein 2 (p33ING2...    51   5e-06
sp|Q9ESK4|ING2_MOUSE  Inhibitor of growth protein 2 (p33ING2...    51   5e-06
sp|P50947|YNJ7_YEAST  Hypothetical 37.0 kDa protein in RAS2-...    51   7e-06
sp|Q9D8Y8|ING5_MOUSE  Inhibitor of growth protein 5                50   2e-05
sp|Q8WYH8|ING5_HUMAN  Inhibitor of growth protein 5 (p28ING5)      50   2e-05
>sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3 protein)
          Length = 421

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 56/250 (22%), Positives = 98/250 (39%), Gaps = 10/250 (4%)
 Frame = +2

Query: 410  KRGRMGFDTNNSQTNTDNRKSIRPKDTTDSFNYKSEKIESFGSISGQNDALMTTVVANGS 589
            K   +G   NNS  + +N  ++       S+N         GS+S    A   T+ A  +
Sbjct: 181  KENTLGCRNNNSTASCNNAYNVNSSQPLASYN--------IGSLSSGAGAGAITMAAAQA 232

Query: 590  LSPASSFM-----GSLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSN 754
            +   +         SL   +   +  D++      I +          +M+ L++++ S+
Sbjct: 233  VQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSIpreTAGYSSSSALMTTLTQNASSS 292

Query: 755  LGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTPGSLNFG 934
              T+   G                      +S  NT+ ++     S   SS +  SL   
Sbjct: 293  -ATDSRSG---------------------RKSKNNTKSSSQQSSSSSSSSSSSSLSL--- 327

Query: 935  MYNEPMISTTSTIQQISHDSQMNLENEILG-----FDTTEELRYCFCNDVSYGDMIACDG 1099
                   S+++ +Q++S  + +  E++        +D  E  RYC CN VSYG+M+ CD 
Sbjct: 328  -----CSSSSTVVQEVSQQATVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDN 381

Query: 1100 VGCpreWFHY 1129
              CP EWFHY
Sbjct: 382  QDCPIEWFHY 391

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 20/43 (46%), Positives = 31/43 (72%)
 Frame = +1

Query: 172 DKIAITDQMKDTFNKMIKKLDTELNKFKLELEADNPGSAEAIE 300
           +K+ + +Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct: 78  EKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120
>sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3 protein)
          Length = 418

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 51/245 (20%), Positives = 94/245 (38%), Gaps = 5/245 (2%)
 Frame = +2

Query: 410  KRGRMGFDTNNSQTNTDNRKSIRPKDTTDSFNYKSEKIESFGSISGQNDALMTTVVANGS 589
            K   +G   NNS  +++N  ++       S+N         GS+S    A   T+ A  +
Sbjct: 181  KENTLGCRNNNSTASSNNAYNVNSSQPLGSYN--------IGSLSSGTGAGAITMAAAQA 232

Query: 590  LSPASSFM-----GSLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSN 754
            +   +         SL   +   +  D++      + +          +M+ L++++ S+
Sbjct: 233  VQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSS 292

Query: 755  LGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTPGSLNFG 934
               +       SG                  S   +  ++++  +S C SS T       
Sbjct: 293  AADS------RSGRKSKNNN---------KSSSQQSSSSSSSSSLSSCSSSST------- 330

Query: 935  MYNEPMISTTSTIQQISHDSQMNLENEILGFDTTEELRYCFCNDVSYGDMIACDGVGCPR 1114
               + +   T+ + +   +SQ++   +        E RYC CN VSYG+M+ CD   CP 
Sbjct: 331  -VVQEISQQTTVVPESDSNSQVDWTYD------PNEPRYCICNQVSYGEMVGCDNQDCPI 383

Query: 1115 EWFHY 1129
            EWFHY
Sbjct: 384  EWFHY 388

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 20/43 (46%), Positives = 31/43 (72%)
 Frame = +1

Query: 172 DKIAITDQMKDTFNKMIKKLDTELNKFKLELEADNPGSAEAIE 300
           +K+ + +Q+ D  ++ ++KLD EL KFK+ELEADN G  E +E
Sbjct: 78  EKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120
>sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1
          Length = 422

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 37/150 (24%), Positives = 60/150 (40%)
 Frame = +2

Query: 680  IEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTN 859
            +E   +     +++  A  ++ G   G + + G D                 S  + +  
Sbjct: 242  VENRTRQVDSHVELFEA-QQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNE 300

Query: 860  TRKTAANDGMSDCGSSRTPGSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILGFDTTE 1039
             R+ A+++   D G+S TP         E    T+   ++    ++       L  D  E
Sbjct: 301  NRENASSNHDHDDGASGTP--------KEKKAKTSKKKKRSKAKAEREASPADLPIDPNE 352

Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129
               YC CN VSYG+MI CD   CP EWFH+
Sbjct: 353  PT-YCLCNQVSYGEMIGCDNDECPIEWFHF 381
>sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1
          Length = 279

 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 36/131 (27%), Positives = 53/131 (40%)
 Frame = +2

Query: 737  EDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTP 916
            +D     G + + G D+S               S  + +   R+ A+N+   D  +S TP
Sbjct: 117  QDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTP 176

Query: 917  GSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILGFDTTEELRYCFCNDVSYGDMIACD 1096
                     E    T+   ++    ++       L  D  E   YC CN VSYG+MI CD
Sbjct: 177  --------KEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPT-YCLCNQVSYGEMIGCD 227

Query: 1097 GVGCpreWFHY 1129
               CP EWFH+
Sbjct: 228  NDECPIEWFHF 238
>sp|P38806|YNG2_YEAST ING1 homolog 2 (ESA1-associated factor 4)
          Length = 282

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 18/27 (66%), Positives = 21/27 (77%)
 Frame = +2

Query: 1049 YCFCNDVSYGDMIACDGVGCpreWFHY 1129
            YCFC  VS+G+M+ACDG  C  EWFHY
Sbjct: 224  YCFCQRVSFGEMVACDGPNCKYEWFHY 250
>sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like
            protein) (ING1Lp) (p32)
          Length = 280

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 19/30 (63%), Positives = 21/30 (70%)
 Frame = +2

Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129
            E  YC CN VSYG+MI CD   CP EWFH+
Sbjct: 211  EPTYCLCNQVSYGEMIGCDNEQCPIEWFHF 240
>sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like
            protein)
          Length = 281

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 19/30 (63%), Positives = 21/30 (70%)
 Frame = +2

Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129
            E  YC CN VSYG+MI CD   CP EWFH+
Sbjct: 212  EPTYCLCNQVSYGEMIGCDNEQCPIEWFHF 241
>sp|P50947|YNJ7_YEAST Hypothetical 37.0 kDa protein in RAS2-RPS7B intergenic region
          Length = 330

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 14/184 (7%)
 Frame = +2

Query: 617  SLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGX 796
            +++  H +  K + K  S+    +++KSE +R  M  A +   G +   +     D    
Sbjct: 130  AMHLHHELMEKIESK--SNSKSSQALKSESRREAM--AANRRQGEHYSASTHQQDDSKND 185

Query: 797  XXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSR----------TPGSLNFGM-YN 943
                         + + +++  R  AAN   +D  + +          +P +++     N
Sbjct: 186  ANYGGSRHESQDHTGNNTNSRKRANAANTNNADPETKKRKRRVATTAVSPSTISTATAVN 245

Query: 944  EPMISTTSTIQQISHDSQMNLENEILGFDTTE---ELRYCFCNDVSYGDMIACDGVGCPR 1114
               I T++  + +S  S  N  N  +    T    E  YC+CN V+YG+M+ CDG  C  
Sbjct: 246  NGRIGTSTASRGVS--SVGNSNNSRISRPKTNDYGEPLYCYCNQVAYGEMVGCDGADCEL 303

Query: 1115 EWFH 1126
            EWFH
Sbjct: 304  EWFH 307
>sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5
          Length = 240

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 18/30 (60%), Positives = 21/30 (70%)
 Frame = +2

Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129
            E  YC C+ VSYG+MI CD   CP EWFH+
Sbjct: 185  EPTYCLCHQVSYGEMIGCDNPDCPIEWFHF 214

 Score = 31.6 bits (70), Expect = 4.4
 Identities = 20/80 (25%), Positives = 40/80 (50%)
 Frame = +1

Query: 46  KSLSISQQVQEYEKILKVYNQNXXXXXXXXXXXXXXVESKNVDKIAITDQMKDTFNKMIK 225
           K+LS +Q+V+  +KI   Y++                +  + DK+ +  Q  +  +K I+
Sbjct: 54  KTLSSAQRVEHLQKIQSAYSK---------------CKEYSDDKVQLAMQTYEMVDKHIR 98

Query: 226 KLDTELNKFKLELEADNPGS 285
           +LD +L +F+ +L+    GS
Sbjct: 99  RLDADLARFEADLKDRMDGS 118
>sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5)
          Length = 240

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 18/30 (60%), Positives = 21/30 (70%)
 Frame = +2

Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129
            E  YC C+ VSYG+MI CD   CP EWFH+
Sbjct: 185  EPTYCLCHQVSYGEMIGCDNPDCPIEWFHF 214

 Score = 31.2 bits (69), Expect = 5.7
 Identities = 20/80 (25%), Positives = 39/80 (48%)
 Frame = +1

Query: 46  KSLSISQQVQEYEKILKVYNQNXXXXXXXXXXXXXXVESKNVDKIAITDQMKDTFNKMIK 225
           K+LS  Q+V+  +KI   Y++                +  + DK+ +  Q  +  +K I+
Sbjct: 54  KTLSPDQRVERLQKIQNAYSK---------------CKEYSDDKVQLAMQTYEMVDKHIR 98

Query: 226 KLDTELNKFKLELEADNPGS 285
           +LD +L +F+ +L+    GS
Sbjct: 99  RLDADLARFEADLKDKMEGS 118
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,396,120
Number of Sequences: 369166
Number of extensions: 1925984
Number of successful extensions: 5258
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5075
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5254
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 12583470240
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00287

  1. Dr_sW_007_P07
  2. Dr_sW_005_A04
  3. Dr_sW_001_K12