Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00287 (1130 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3... 65 5e-10 sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3... 63 1e-09 sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1 56 2e-07 sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1 54 8e-07 sp|P38806|YNG2_YEAST ING1 homolog 2 (ESA1-associated factor 4) 52 4e-06 sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2... 51 5e-06 sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2... 51 5e-06 sp|P50947|YNJ7_YEAST Hypothetical 37.0 kDa protein in RAS2-... 51 7e-06 sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5 50 2e-05 sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5) 50 2e-05
>sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3 protein) Length = 421 Score = 64.7 bits (156), Expect = 5e-10 Identities = 56/250 (22%), Positives = 98/250 (39%), Gaps = 10/250 (4%) Frame = +2 Query: 410 KRGRMGFDTNNSQTNTDNRKSIRPKDTTDSFNYKSEKIESFGSISGQNDALMTTVVANGS 589 K +G NNS + +N ++ S+N GS+S A T+ A + Sbjct: 181 KENTLGCRNNNSTASCNNAYNVNSSQPLASYN--------IGSLSSGAGAGAITMAAAQA 232 Query: 590 LSPASSFM-----GSLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSN 754 + + SL + + D++ I + +M+ L++++ S+ Sbjct: 233 VQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSIpreTAGYSSSSALMTTLTQNASSS 292 Query: 755 LGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTPGSLNFG 934 T+ G +S NT+ ++ S SS + SL Sbjct: 293 -ATDSRSG---------------------RKSKNNTKSSSQQSSSSSSSSSSSSLSL--- 327 Query: 935 MYNEPMISTTSTIQQISHDSQMNLENEILG-----FDTTEELRYCFCNDVSYGDMIACDG 1099 S+++ +Q++S + + E++ +D E RYC CN VSYG+M+ CD Sbjct: 328 -----CSSSSTVVQEVSQQATVVPESDSNSQVDWTYDPNEP-RYCICNQVSYGEMVGCDN 381 Query: 1100 VGCpreWFHY 1129 CP EWFHY Sbjct: 382 QDCPIEWFHY 391
Score = 46.2 bits (108), Expect = 2e-04 Identities = 20/43 (46%), Positives = 31/43 (72%) Frame = +1 Query: 172 DKIAITDQMKDTFNKMIKKLDTELNKFKLELEADNPGSAEAIE 300 +K+ + +Q+ D ++ ++KLD EL KFK+ELEADN G E +E Sbjct: 78 EKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120
>sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3 protein) Length = 418 Score = 63.2 bits (152), Expect = 1e-09 Identities = 51/245 (20%), Positives = 94/245 (38%), Gaps = 5/245 (2%) Frame = +2 Query: 410 KRGRMGFDTNNSQTNTDNRKSIRPKDTTDSFNYKSEKIESFGSISGQNDALMTTVVANGS 589 K +G NNS +++N ++ S+N GS+S A T+ A + Sbjct: 181 KENTLGCRNNNSTASSNNAYNVNSSQPLGSYN--------IGSLSSGTGAGAITMAAAQA 232 Query: 590 LSPASSFM-----GSLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSN 754 + + SL + + D++ + + +M+ L++++ S+ Sbjct: 233 VQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMARETVGYSSSSALMTTLTQNASSS 292 Query: 755 LGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTPGSLNFG 934 + SG S + ++++ +S C SS T Sbjct: 293 AADS------RSGRKSKNNN---------KSSSQQSSSSSSSSSLSSCSSSST------- 330 Query: 935 MYNEPMISTTSTIQQISHDSQMNLENEILGFDTTEELRYCFCNDVSYGDMIACDGVGCPR 1114 + + T+ + + +SQ++ + E RYC CN VSYG+M+ CD CP Sbjct: 331 -VVQEISQQTTVVPESDSNSQVDWTYD------PNEPRYCICNQVSYGEMVGCDNQDCPI 383 Query: 1115 EWFHY 1129 EWFHY Sbjct: 384 EWFHY 388
Score = 46.2 bits (108), Expect = 2e-04 Identities = 20/43 (46%), Positives = 31/43 (72%) Frame = +1 Query: 172 DKIAITDQMKDTFNKMIKKLDTELNKFKLELEADNPGSAEAIE 300 +K+ + +Q+ D ++ ++KLD EL KFK+ELEADN G E +E Sbjct: 78 EKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120
>sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1 Length = 422 Score = 55.8 bits (133), Expect = 2e-07 Identities = 37/150 (24%), Positives = 60/150 (40%) Frame = +2 Query: 680 IEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTN 859 +E + +++ A ++ G G + + G D S + + Sbjct: 242 VENRTRQVDSHVELFEA-QQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNE 300 Query: 860 TRKTAANDGMSDCGSSRTPGSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILGFDTTE 1039 R+ A+++ D G+S TP E T+ ++ ++ L D E Sbjct: 301 NRENASSNHDHDDGASGTP--------KEKKAKTSKKKKRSKAKAEREASPADLPIDPNE 352 Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129 YC CN VSYG+MI CD CP EWFH+ Sbjct: 353 PT-YCLCNQVSYGEMIGCDNDECPIEWFHF 381
>sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1 Length = 279 Score = 53.9 bits (128), Expect = 8e-07 Identities = 36/131 (27%), Positives = 53/131 (40%) Frame = +2 Query: 737 EDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTP 916 +D G + + G D+S S + + R+ A+N+ D +S TP Sbjct: 117 QDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTP 176 Query: 917 GSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILGFDTTEELRYCFCNDVSYGDMIACD 1096 E T+ ++ ++ L D E YC CN VSYG+MI CD Sbjct: 177 --------KEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPT-YCLCNQVSYGEMIGCD 227 Query: 1097 GVGCpreWFHY 1129 CP EWFH+ Sbjct: 228 NDECPIEWFHF 238
>sp|P38806|YNG2_YEAST ING1 homolog 2 (ESA1-associated factor 4) Length = 282 Score = 51.6 bits (122), Expect = 4e-06 Identities = 18/27 (66%), Positives = 21/27 (77%) Frame = +2 Query: 1049 YCFCNDVSYGDMIACDGVGCpreWFHY 1129 YCFC VS+G+M+ACDG C EWFHY Sbjct: 224 YCFCQRVSFGEMVACDGPNCKYEWFHY 250
>sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32) Length = 280 Score = 51.2 bits (121), Expect = 5e-06 Identities = 19/30 (63%), Positives = 21/30 (70%) Frame = +2 Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129 E YC CN VSYG+MI CD CP EWFH+ Sbjct: 211 EPTYCLCNQVSYGEMIGCDNEQCPIEWFHF 240
>sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) Length = 281 Score = 51.2 bits (121), Expect = 5e-06 Identities = 19/30 (63%), Positives = 21/30 (70%) Frame = +2 Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129 E YC CN VSYG+MI CD CP EWFH+ Sbjct: 212 EPTYCLCNQVSYGEMIGCDNEQCPIEWFHF 241
>sp|P50947|YNJ7_YEAST Hypothetical 37.0 kDa protein in RAS2-RPS7B intergenic region Length = 330 Score = 50.8 bits (120), Expect = 7e-06 Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 14/184 (7%) Frame = +2 Query: 617 SLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGX 796 +++ H + K + K S+ +++KSE +R M A + G + + D Sbjct: 130 AMHLHHELMEKIESK--SNSKSSQALKSESRREAM--AANRRQGEHYSASTHQQDDSKND 185 Query: 797 XXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSR----------TPGSLNFGM-YN 943 + + +++ R AAN +D + + +P +++ N Sbjct: 186 ANYGGSRHESQDHTGNNTNSRKRANAANTNNADPETKKRKRRVATTAVSPSTISTATAVN 245 Query: 944 EPMISTTSTIQQISHDSQMNLENEILGFDTTE---ELRYCFCNDVSYGDMIACDGVGCPR 1114 I T++ + +S S N N + T E YC+CN V+YG+M+ CDG C Sbjct: 246 NGRIGTSTASRGVS--SVGNSNNSRISRPKTNDYGEPLYCYCNQVAYGEMVGCDGADCEL 303 Query: 1115 EWFH 1126 EWFH Sbjct: 304 EWFH 307
>sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5 Length = 240 Score = 49.7 bits (117), Expect = 2e-05 Identities = 18/30 (60%), Positives = 21/30 (70%) Frame = +2 Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129 E YC C+ VSYG+MI CD CP EWFH+ Sbjct: 185 EPTYCLCHQVSYGEMIGCDNPDCPIEWFHF 214
Score = 31.6 bits (70), Expect = 4.4 Identities = 20/80 (25%), Positives = 40/80 (50%) Frame = +1 Query: 46 KSLSISQQVQEYEKILKVYNQNXXXXXXXXXXXXXXVESKNVDKIAITDQMKDTFNKMIK 225 K+LS +Q+V+ +KI Y++ + + DK+ + Q + +K I+ Sbjct: 54 KTLSSAQRVEHLQKIQSAYSK---------------CKEYSDDKVQLAMQTYEMVDKHIR 98 Query: 226 KLDTELNKFKLELEADNPGS 285 +LD +L +F+ +L+ GS Sbjct: 99 RLDADLARFEADLKDRMDGS 118
>sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5) Length = 240 Score = 49.7 bits (117), Expect = 2e-05 Identities = 18/30 (60%), Positives = 21/30 (70%) Frame = +2 Query: 1040 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 1129 E YC C+ VSYG+MI CD CP EWFH+ Sbjct: 185 EPTYCLCHQVSYGEMIGCDNPDCPIEWFHF 214
Score = 31.2 bits (69), Expect = 5.7 Identities = 20/80 (25%), Positives = 39/80 (48%) Frame = +1 Query: 46 KSLSISQQVQEYEKILKVYNQNXXXXXXXXXXXXXXVESKNVDKIAITDQMKDTFNKMIK 225 K+LS Q+V+ +KI Y++ + + DK+ + Q + +K I+ Sbjct: 54 KTLSPDQRVERLQKIQNAYSK---------------CKEYSDDKVQLAMQTYEMVDKHIR 98 Query: 226 KLDTELNKFKLELEADNPGS 285 +LD +L +F+ +L+ GS Sbjct: 99 RLDADLARFEADLKDKMEGS 118
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 106,396,120 Number of Sequences: 369166 Number of extensions: 1925984 Number of successful extensions: 5258 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5075 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5254 length of database: 68,354,980 effective HSP length: 112 effective length of database: 47,664,660 effective search space used: 12583470240 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)