Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_K12
(837 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3... 60 6e-09
sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3... 59 2e-08
sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1 40 0.008
sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1 38 0.030
sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2... 35 0.26
sp|P50947|YNJ7_YEAST Hypothetical 37.0 kDa protein in RAS2-... 35 0.26
sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2... 35 0.26
sp|P38806|YNG2_YEAST ING1 homolog 2 (ESA1-associated factor 4) 33 0.75
sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5 33 0.97
sp|P32583|SRP40_YEAST Suppressor protein SRP40 33 0.97
>sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3 protein)
Length = 418
Score = 60.5 bits (145), Expect = 6e-09
Identities = 69/294 (23%), Positives = 121/294 (41%), Gaps = 16/294 (5%)
Frame = +3
Query: 3 KKLDTELNKFKLELEADNPGSAEAIEL------MVNQQIKSGVNEGIQRVERKRIKRGRM 164
+KLD EL KFK+ELEADN G E +E +Q + + VE+++
Sbjct: 95 RKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVNNHHAHSHTPVEKRK------ 148
Query: 165 GFDTNNSQTNTDN--RKSIRPKDTTDSFNYKSEKIESFGSISGQNDALMTTVVANGSLSP 338
++ + T TD+ K + + + + K + G + + A S P
Sbjct: 149 -YNPTSHHTTTDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASSNNAYNVNSSQP 207
Query: 339 ASSF-MGSLNTPHSIKRKFDWKHASSIPIEKSVKSERK--RLKMMSALSEDSGSNLGTND 509
S+ +GSL++ A ++ +K R+ LK +++ LG
Sbjct: 208 LGSYNIGSLSSGTG-AGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEF 266
Query: 510 ELGLDESG-XXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTPGSLNFGMYNE 686
+ + G S S +D+ + + + N+ S SS+ S +
Sbjct: 267 SMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKS---SSQQSSSSSSSSSLS 323
Query: 687 PMISTTSTIQQISHDSQMNLENEILG-FDTT---EELRYCFCNDVSYGDMIACD 836
S+++ +Q+IS + + E++ D T E RYC CN VSYG+M+ CD
Sbjct: 324 SCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCD 377
>sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3 protein)
Length = 421
Score = 58.5 bits (140), Expect = 2e-08
Identities = 70/317 (22%), Positives = 123/317 (38%), Gaps = 39/317 (12%)
Frame = +3
Query: 3 KKLDTELNKFKLELEADNPGSAEAIELMV------NQQIKSGVNEGIQRVERKRIK---- 152
+KLD EL KFK+ELEADN G E +E +Q + + VE+++
Sbjct: 95 RKLDQELAKFKMELEADNAGITEILERRSLELDAPSQPVNNHHAHSHTPVEKRKYNPTSH 154
Query: 153 ------------RGRMGFDTNNSQTNTDNRKSIRPKDTTDSFNY-----KSEKIESF--G 275
+ T S + +N R ++T S N S+ + S+ G
Sbjct: 155 HAAADHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASCNNAYNVNSSQPLASYNIG 214
Query: 276 SISGQNDALMTTVVANGSLSPASSFM-----GSLNTPHSIKRKFDWKHASSIPIEKSVKS 440
S+S A T+ A ++ + SL + + D++ I +
Sbjct: 215 SLSSGAGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSIpreTAG 274
Query: 441 ERKRLKMMSALSEDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAAN 620
+M+ L++++ S+ T+ G +S NT+ ++
Sbjct: 275 YSSSSALMTTLTQNASSS-ATDSRSG---------------------RKSKNNTKSSSQQ 312
Query: 621 DGMSDCGSSRTPGSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILG-----FDTTEEL 785
S SS + SL S+++ +Q++S + + E++ +D E
Sbjct: 313 SSSSSSSSSSSSLSL--------CSSSSTVVQEVSQQATVVPESDSNSQVDWTYDPNEP- 363
Query: 786 RYCFCNDVSYGDMIACD 836
RYC CN VSYG+M+ CD
Sbjct: 364 RYCICNQVSYGEMVGCD 380
>sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1
Length = 422
Score = 40.0 bits (92), Expect = 0.008
Identities = 31/139 (22%), Positives = 53/139 (38%)
Frame = +3
Query: 420 IEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTN 599
+E + +++ A ++ G G + + G D S + +
Sbjct: 242 VENRTRQVDSHVELFEA-QQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNE 300
Query: 600 TRKTAANDGMSDCGSSRTPGSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILGFDTTE 779
R+ A+++ D G+S TP E T+ ++ ++ L D E
Sbjct: 301 NRENASSNHDHDDGASGTP--------KEKKAKTSKKKKRSKAKAEREASPADLPIDPNE 352
Query: 780 ELRYCFCNDVSYGDMIACD 836
YC CN VSYG+MI CD
Sbjct: 353 PT-YCLCNQVSYGEMIGCD 370
>sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1
Length = 279
Score = 38.1 bits (87), Expect = 0.030
Identities = 30/120 (25%), Positives = 46/120 (38%)
Frame = +3
Query: 477 EDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTP 656
+D G + + G D+S S + + R+ A+N+ D +S TP
Sbjct: 117 QDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTP 176
Query: 657 GSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILGFDTTEELRYCFCNDVSYGDMIACD 836
E T+ ++ ++ L D E YC CN VSYG+MI CD
Sbjct: 177 --------KEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPT-YCLCNQVSYGEMIGCD 227
>sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like
protein) (ING1Lp) (p32)
Length = 280
Score = 35.0 bits (79), Expect = 0.26
Identities = 13/19 (68%), Positives = 14/19 (73%)
Frame = +3
Query: 780 ELRYCFCNDVSYGDMIACD 836
E YC CN VSYG+MI CD
Sbjct: 211 EPTYCLCNQVSYGEMIGCD 229
>sp|P50947|YNJ7_YEAST Hypothetical 37.0 kDa protein in RAS2-RPS7B intergenic region
Length = 330
Score = 35.0 bits (79), Expect = 0.26
Identities = 37/174 (21%), Positives = 71/174 (40%), Gaps = 14/174 (8%)
Frame = +3
Query: 357 SLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGX 536
+++ H + K + K S+ +++KSE +R M A + G + + D
Sbjct: 130 AMHLHHELMEKIESK--SNSKSSQALKSESRREAM--AANRRQGEHYSASTHQQDDSKND 185
Query: 537 XXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSR----------TPGSLNFGM-YN 683
+ + +++ R AAN +D + + +P +++ N
Sbjct: 186 ANYGGSRHESQDHTGNNTNSRKRANAANTNNADPETKKRKRRVATTAVSPSTISTATAVN 245
Query: 684 EPMISTTSTIQQISHDSQMNLENEILGFDTTE---ELRYCFCNDVSYGDMIACD 836
I T++ + +S S N N + T E YC+CN V+YG+M+ CD
Sbjct: 246 NGRIGTSTASRGVS--SVGNSNNSRISRPKTNDYGEPLYCYCNQVAYGEMVGCD 297
>sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like
protein)
Length = 281
Score = 35.0 bits (79), Expect = 0.26
Identities = 13/19 (68%), Positives = 14/19 (73%)
Frame = +3
Query: 780 ELRYCFCNDVSYGDMIACD 836
E YC CN VSYG+MI CD
Sbjct: 212 EPTYCLCNQVSYGEMIGCD 230
>sp|P38806|YNG2_YEAST ING1 homolog 2 (ESA1-associated factor 4)
Length = 282
Score = 33.5 bits (75), Expect = 0.75
Identities = 11/16 (68%), Positives = 14/16 (87%)
Frame = +3
Query: 789 YCFCNDVSYGDMIACD 836
YCFC VS+G+M+ACD
Sbjct: 224 YCFCQRVSFGEMVACD 239
>sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5
Length = 240
Score = 33.1 bits (74), Expect = 0.97
Identities = 12/19 (63%), Positives = 14/19 (73%)
Frame = +3
Query: 780 ELRYCFCNDVSYGDMIACD 836
E YC C+ VSYG+MI CD
Sbjct: 185 EPTYCLCHQVSYGEMIGCD 203
>sp|P32583|SRP40_YEAST Suppressor protein SRP40
Length = 406
Score = 33.1 bits (74), Expect = 0.97
Identities = 39/199 (19%), Positives = 81/199 (40%), Gaps = 1/199 (0%)
Frame = +3
Query: 171 DTNNSQTNTDNRKSIRPKDTTDSFNYKSEKIESFGSISGQNDALMTTVVANGSLSPASSF 350
++++S +++ + S D++DS + S S S S + + ++ S S +SS
Sbjct: 51 ESSSSSSSSSSSSSSDSSDSSDSESSSSSSSSSSSSSSSSDSESSSESDSSSSGSSSSSS 110
Query: 351 MGSLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDES 530
S + + + + K + + K E K+ K S S S+ + ES
Sbjct: 111 SSSDESSSESESEDETKKRARESDNEDAK-ETKKAKTEPESSSSSESSSSGSSSSSESES 169
Query: 531 GXXXXXXXXXXXXXVSVSESDTNT-RKTAANDGMSDCGSSRTPGSLNFGMYNEPMISTTS 707
G S SESD+ + +++++ SD S S + ++ S++S
Sbjct: 170 GSESDSDSSSSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSS 229
Query: 708 TIQQISHDSQMNLENEILG 764
+ DS + +++ G
Sbjct: 230 SSSDSDSDSDSSSDSDSSG 248
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,152,537
Number of Sequences: 369166
Number of extensions: 1534823
Number of successful extensions: 4329
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4203
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4324
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8148988185
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)