Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_A04
(892 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3... 81 3e-15
sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3... 79 1e-14
sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1 56 2e-07
sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1 54 6e-07
sp|P38806|YNG2_YEAST ING1 homolog 2 (ESA1-associated factor 4) 52 3e-06
sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2... 51 4e-06
sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2... 51 4e-06
sp|P50947|YNJ7_YEAST Hypothetical 37.0 kDa protein in RAS2-... 51 5e-06
sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5 50 1e-05
sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5) 50 1e-05
>sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3 protein)
Length = 418
Score = 81.3 bits (199), Expect = 3e-15
Identities = 77/312 (24%), Positives = 132/312 (42%), Gaps = 16/312 (5%)
Frame = +1
Query: 4 DTFNKMIKKLDTELNKFKLELEADNPGSAEAIEL------MVNQQIKSGVNEGIQRVERK 165
D ++ ++KLD EL KFK+ELEADN G E +E +Q + + VE++
Sbjct: 88 DLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDTPSQPVNNHHAHSHTPVEKR 147
Query: 166 RIKRGRMGFDTNNSQTNTDN--RKSIRPKDTTDSFNYKSEKIESFGSISGQNDALMTTVV 339
+ ++ + T TD+ K + + + + K + G + + A
Sbjct: 148 K-------YNPTSHHTTTDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASSNNAY 200
Query: 340 ANGSLSPASSF-MGSLNTPHSIKRKFDWKHASSIPIEKSVKSERK--RLKMMSALSEDSG 510
S P S+ +GSL++ A ++ +K R+ LK +++
Sbjct: 201 NVNSSQPLGSYNIGSLSSGTG-AGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNND 259
Query: 511 SNLGTNDELGLDESG-XXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTPGSL 687
LG + + G S S +D+ + + + N+ S SS+ S
Sbjct: 260 FQLGKEFSMARETVGYSSSSALMTTLTQNASSSAADSRSGRKSKNNNKS---SSQQSSSS 316
Query: 688 NFGMYNEPMISTTSTIQQISHDSQMNLENEILG-FDTT---EELRYCFCNDVSYGDMIAC 855
+ S+++ +Q+IS + + E++ D T E RYC CN VSYG+M+ C
Sbjct: 317 SSSSSLSSCSSSSTVVQEISQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGC 376
Query: 856 DGVGCpreWFHY 891
D CP EWFHY
Sbjct: 377 DNQDCPIEWFHY 388
>sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3 protein)
Length = 421
Score = 79.3 bits (194), Expect = 1e-14
Identities = 78/335 (23%), Positives = 134/335 (40%), Gaps = 39/335 (11%)
Frame = +1
Query: 4 DTFNKMIKKLDTELNKFKLELEADNPGSAEAIELMV------NQQIKSGVNEGIQRVERK 165
D ++ ++KLD EL KFK+ELEADN G E +E +Q + + VE++
Sbjct: 88 DLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQPVNNHHAHSHTPVEKR 147
Query: 166 RIK----------------RGRMGFDTNNSQTNTDNRKSIRPKDTTDSFNY-----KSEK 282
+ + T S + +N R ++T S N S+
Sbjct: 148 KYNPTSHHAAADHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASCNNAYNVNSSQP 207
Query: 283 IESF--GSISGQNDALMTTVVANGSLSPASSFM-----GSLNTPHSIKRKFDWKHASSIP 441
+ S+ GS+S A T+ A ++ + SL + + D++
Sbjct: 208 LASYNIGSLSSGAGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFS 267
Query: 442 IEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTN 621
I + +M+ L++++ S+ T+ G +S N
Sbjct: 268 IpreTAGYSSSSALMTTLTQNASSS-ATDSRSG---------------------RKSKNN 305
Query: 622 TRKTAANDGMSDCGSSRTPGSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILG----- 786
T+ ++ S SS + SL S+++ +Q++S + + E++
Sbjct: 306 TKSSSQQSSSSSSSSSSSSLSL--------CSSSSTVVQEVSQQATVVPESDSNSQVDWT 357
Query: 787 FDTTEELRYCFCNDVSYGDMIACDGVGCpreWFHY 891
+D E RYC CN VSYG+M+ CD CP EWFHY
Sbjct: 358 YDPNEP-RYCICNQVSYGEMVGCDNQDCPIEWFHY 391
>sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1
Length = 422
Score = 55.8 bits (133), Expect = 2e-07
Identities = 37/150 (24%), Positives = 60/150 (40%)
Frame = +1
Query: 442 IEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTN 621
+E + +++ A ++ G G + + G D S + +
Sbjct: 242 VENRTRQVDSHVELFEA-QQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNE 300
Query: 622 TRKTAANDGMSDCGSSRTPGSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILGFDTTE 801
R+ A+++ D G+S TP E T+ ++ ++ L D E
Sbjct: 301 NRENASSNHDHDDGASGTP--------KEKKAKTSKKKKRSKAKAEREASPADLPIDPNE 352
Query: 802 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 891
YC CN VSYG+MI CD CP EWFH+
Sbjct: 353 PT-YCLCNQVSYGEMIGCDNDECPIEWFHF 381
>sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1
Length = 279
Score = 53.9 bits (128), Expect = 6e-07
Identities = 36/131 (27%), Positives = 53/131 (40%)
Frame = +1
Query: 499 EDSGSNLGTNDELGLDESGXXXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSRTP 678
+D G + + G D+S S + + R+ A+N+ D +S TP
Sbjct: 117 QDISDGTGGSGKAGQDKSKSEAITQADKPNNKRSRRQRNNENRENASNNHDHDDITSGTP 176
Query: 679 GSLNFGMYNEPMISTTSTIQQISHDSQMNLENEILGFDTTEELRYCFCNDVSYGDMIACD 858
E T+ ++ ++ L D E YC CN VSYG+MI CD
Sbjct: 177 --------KEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPT-YCLCNQVSYGEMIGCD 227
Query: 859 GVGCpreWFHY 891
CP EWFH+
Sbjct: 228 NDECPIEWFHF 238
>sp|P38806|YNG2_YEAST ING1 homolog 2 (ESA1-associated factor 4)
Length = 282
Score = 51.6 bits (122), Expect = 3e-06
Identities = 18/27 (66%), Positives = 21/27 (77%)
Frame = +1
Query: 811 YCFCNDVSYGDMIACDGVGCpreWFHY 891
YCFC VS+G+M+ACDG C EWFHY
Sbjct: 224 YCFCQRVSFGEMVACDGPNCKYEWFHY 250
>sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like
protein) (ING1Lp) (p32)
Length = 280
Score = 51.2 bits (121), Expect = 4e-06
Identities = 19/30 (63%), Positives = 21/30 (70%)
Frame = +1
Query: 802 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 891
E YC CN VSYG+MI CD CP EWFH+
Sbjct: 211 EPTYCLCNQVSYGEMIGCDNEQCPIEWFHF 240
>sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like
protein)
Length = 281
Score = 51.2 bits (121), Expect = 4e-06
Identities = 19/30 (63%), Positives = 21/30 (70%)
Frame = +1
Query: 802 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 891
E YC CN VSYG+MI CD CP EWFH+
Sbjct: 212 EPTYCLCNQVSYGEMIGCDNEQCPIEWFHF 241
>sp|P50947|YNJ7_YEAST Hypothetical 37.0 kDa protein in RAS2-RPS7B intergenic region
Length = 330
Score = 50.8 bits (120), Expect = 5e-06
Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 14/184 (7%)
Frame = +1
Query: 379 SLNTPHSIKRKFDWKHASSIPIEKSVKSERKRLKMMSALSEDSGSNLGTNDELGLDESGX 558
+++ H + K + K S+ +++KSE +R M A + G + + D
Sbjct: 130 AMHLHHELMEKIESK--SNSKSSQALKSESRREAM--AANRRQGEHYSASTHQQDDSKND 185
Query: 559 XXXXXXXXXXXXVSVSESDTNTRKTAANDGMSDCGSSR----------TPGSLNFGM-YN 705
+ + +++ R AAN +D + + +P +++ N
Sbjct: 186 ANYGGSRHESQDHTGNNTNSRKRANAANTNNADPETKKRKRRVATTAVSPSTISTATAVN 245
Query: 706 EPMISTTSTIQQISHDSQMNLENEILGFDTTE---ELRYCFCNDVSYGDMIACDGVGCPR 876
I T++ + +S S N N + T E YC+CN V+YG+M+ CDG C
Sbjct: 246 NGRIGTSTASRGVS--SVGNSNNSRISRPKTNDYGEPLYCYCNQVAYGEMVGCDGADCEL 303
Query: 877 EWFH 888
EWFH
Sbjct: 304 EWFH 307
>sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5
Length = 240
Score = 49.7 bits (117), Expect = 1e-05
Identities = 18/30 (60%), Positives = 21/30 (70%)
Frame = +1
Query: 802 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 891
E YC C+ VSYG+MI CD CP EWFH+
Sbjct: 185 EPTYCLCHQVSYGEMIGCDNPDCPIEWFHF 214
>sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5)
Length = 240
Score = 49.7 bits (117), Expect = 1e-05
Identities = 18/30 (60%), Positives = 21/30 (70%)
Frame = +1
Query: 802 ELRYCFCNDVSYGDMIACDGVGCpreWFHY 891
E YC C+ VSYG+MI CD CP EWFH+
Sbjct: 185 EPTYCLCHQVSYGEMIGCDNPDCPIEWFHF 214
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.310 0.127 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,308,892
Number of Sequences: 369166
Number of extensions: 1670087
Number of successful extensions: 3600
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3494
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3597
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)