Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_P07
(893 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3... 46 1e-04
sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3... 46 1e-04
sp|P55283|CADH4_HUMAN Cadherin-4 precursor (Retinal-cadheri... 34 0.63
sp|P24503|CADH4_CHICK Cadherin-4 precursor (Retinal-cadheri... 32 2.4
sp|P39038|CADH4_MOUSE Cadherin-4 precursor (Retinal-cadheri... 32 2.4
sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5 32 3.1
sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5) 31 4.1
sp|P10288|CADH2_CHICK Neural-cadherin precursor (N-cadherin... 30 7.0
sp|P79883|CADH4_XENLA Cadherin-4 precursor (Maternally expr... 30 7.0
sp|Q99MZ3|WBS14_MOUSE Williams-Beuren syndrome chromosome r... 30 9.1
>sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3 protein)
Length = 418
Score = 46.2 bits (108), Expect = 1e-04
Identities = 20/43 (46%), Positives = 31/43 (72%)
Frame = +1
Query: 172 DKIAITDQMKDTFNKMIKKLDTELNKFKLELEADNPGSAEAIE 300
+K+ + +Q+ D ++ ++KLD EL KFK+ELEADN G E +E
Sbjct: 78 EKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120
>sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3 protein)
Length = 421
Score = 46.2 bits (108), Expect = 1e-04
Identities = 20/43 (46%), Positives = 31/43 (72%)
Frame = +1
Query: 172 DKIAITDQMKDTFNKMIKKLDTELNKFKLELEADNPGSAEAIE 300
+K+ + +Q+ D ++ ++KLD EL KFK+ELEADN G E +E
Sbjct: 78 EKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILE 120
>sp|P55283|CADH4_HUMAN Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD)
Length = 916
Score = 33.9 bits (76), Expect = 0.63
Identities = 24/96 (25%), Positives = 45/96 (46%)
Frame = -3
Query: 675 DEACFQSNLRFIE*GVFNEPINEEAGDNEPLATTVVIKASFCPDIDPKLSIFSDL*LKES 496
D A + ++E G+++ PI N PL+ T +IK CP D D +
Sbjct: 670 DYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDN-----GDCTTIGA 724
Query: 495 VVSFGLIDFRLLSVFVCELFVSKPILPRFILFLSTR 388
V + GL ++++ +C L + +L F++++ R
Sbjct: 725 VAAAGLGTGAIVAILICILILLTMVL-LFVMWMKRR 759
>sp|P24503|CADH4_CHICK Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD)
Length = 913
Score = 32.0 bits (71), Expect = 2.4
Identities = 23/96 (23%), Positives = 44/96 (45%)
Frame = -3
Query: 675 DEACFQSNLRFIE*GVFNEPINEEAGDNEPLATTVVIKASFCPDIDPKLSIFSDL*LKES 496
D A + ++E GV++ PI N PL T +IK CP + D +
Sbjct: 667 DYAQLSLRIMYLEAGVYDVPIIVTDSGNPPLYNTSIIKVKVCPCDEN-----GDCTTIGA 721
Query: 495 VVSFGLIDFRLLSVFVCELFVSKPILPRFILFLSTR 388
V + GL ++++ +C + + +L F++++ R
Sbjct: 722 VAAAGLGTGAIIAILICIIILLTMVL-LFVVWMKRR 756
>sp|P39038|CADH4_MOUSE Cadherin-4 precursor (Retinal-cadherin) (R-cadherin) (R-CAD)
Length = 913
Score = 32.0 bits (71), Expect = 2.4
Identities = 16/43 (37%), Positives = 22/43 (51%)
Frame = -3
Query: 675 DEACFQSNLRFIE*GVFNEPINEEAGDNEPLATTVVIKASFCP 547
D A + ++E GV++ PI N PL+ T VIK CP
Sbjct: 667 DYAQLSLRILYLEAGVYDVPIIVTDSGNPPLSNTSVIKVKVCP 709
>sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5
Length = 240
Score = 31.6 bits (70), Expect = 3.1
Identities = 20/80 (25%), Positives = 40/80 (50%)
Frame = +1
Query: 46 KSLSISQQVQEYEKILKVYNQNXXXXXXXXXXXXXXVESKNVDKIAITDQMKDTFNKMIK 225
K+LS +Q+V+ +KI Y++ + + DK+ + Q + +K I+
Sbjct: 54 KTLSSAQRVEHLQKIQSAYSK---------------CKEYSDDKVQLAMQTYEMVDKHIR 98
Query: 226 KLDTELNKFKLELEADNPGS 285
+LD +L +F+ +L+ GS
Sbjct: 99 RLDADLARFEADLKDRMDGS 118
>sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5)
Length = 240
Score = 31.2 bits (69), Expect = 4.1
Identities = 20/80 (25%), Positives = 39/80 (48%)
Frame = +1
Query: 46 KSLSISQQVQEYEKILKVYNQNXXXXXXXXXXXXXXVESKNVDKIAITDQMKDTFNKMIK 225
K+LS Q+V+ +KI Y++ + + DK+ + Q + +K I+
Sbjct: 54 KTLSPDQRVERLQKIQNAYSK---------------CKEYSDDKVQLAMQTYEMVDKHIR 98
Query: 226 KLDTELNKFKLELEADNPGS 285
+LD +L +F+ +L+ GS
Sbjct: 99 RLDADLARFEADLKDKMEGS 118
>sp|P10288|CADH2_CHICK Neural-cadherin precursor (N-cadherin) (Cadherin-2)
Length = 912
Score = 30.4 bits (67), Expect = 7.0
Identities = 22/96 (22%), Positives = 45/96 (46%)
Frame = -3
Query: 675 DEACFQSNLRFIE*GVFNEPINEEAGDNEPLATTVVIKASFCPDIDPKLSIFSDL*LKES 496
D A +RF+E G+++ PI N ++T V+K C + I D +
Sbjct: 666 DHAQLSLRIRFLEAGIYDVPIVITDSGNPHASSTSVLKVKVC-----QCDINGDCTDVDR 720
Query: 495 VVSFGLIDFRLLSVFVCELFVSKPILPRFILFLSTR 388
+V GL ++++ +C + + +L F++++ R
Sbjct: 721 IVGAGLGTGAIIAILLCIIILLILVL-MFVVWMKRR 755
>sp|P79883|CADH4_XENLA Cadherin-4 precursor (Maternally expressed neural cadherin)
(XmN-cadherin)
Length = 922
Score = 30.4 bits (67), Expect = 7.0
Identities = 20/86 (23%), Positives = 40/86 (46%)
Frame = -3
Query: 645 FIE*GVFNEPINEEAGDNEPLATTVVIKASFCPDIDPKLSIFSDL*LKESVVSFGLIDFR 466
++E G+++ P+ N PL T +IK CP D +V + GL
Sbjct: 686 YLESGMYDVPVIVTDSGNPPLYNTSIIKVKVCP-----CDNNGDCTTIGAVAAAGLGTGA 740
Query: 465 LLSVFVCELFVSKPILPRFILFLSTR 388
++S+ +C + + +L F++++ R
Sbjct: 741 IISILICIIILLSMVL-LFVMWMKRR 765
>sp|Q99MZ3|WBS14_MOUSE Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx
interactor) (MLX-interacting protein-like)
Length = 864
Score = 30.0 bits (66), Expect = 9.1
Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 1/71 (1%)
Frame = +2
Query: 479 RPKDTTDSFNYKSEKIESFGSISGQNDALMTT-VVANGSLSPASSFMGSLNTPHSIKRKF 655
RP T S NY SFG ++ D+L ++ ++A SPASS S TPHS +
Sbjct: 307 RPPQTPTSSNYIESP--SFGPMA---DSLFSSGILAPEMPSPASSSSSSGMTPHSGNTRL 361
Query: 656 DWKHASSIPIE 688
+++ S P++
Sbjct: 362 QARNSCSGPLD 372
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,969,343
Number of Sequences: 369166
Number of extensions: 1320745
Number of successful extensions: 3265
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3192
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3265
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)