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Planaria EST Database

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00245
         (665 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P28797|GRN_CAVPO  Granulins precursor (Proepithelin) (PEP...   108   1e-23
sp|P23785|GRN_RAT  Granulins precursor [Contains: Acrogranin...   108   1e-23
sp|P28798|GRN_MOUSE  Granulins precursor (Acrogranin) (Proep...   106   5e-23
sp|P28799|GRN_HUMAN  Granulins precursor (Proepithelin) (PEP...   106   5e-23
sp|P80059|PMD1_LOCMI  Pars intercerebralis major peptide D1 ...    63   8e-10
sp|P80930|ENA1_HORSE  Antimicrobial peptide eNAP-1                 57   4e-08
sp|P81013|GRN1_CYPCA  Granulin-1                                   52   1e-06
sp|P81014|GRN2_CYPCA  Granulin-2                                   49   9e-06
sp|P81015|GRN3_CYPCA  Granulin-3                                   45   2e-04
sp|P43297|RD21A_ARATH  Cysteine proteinase RD21a precursor (...    43   8e-04

>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
           Granulin-1; Granulin-2; Granulin-3; Granulin-4;
           Granulin-5; Granulin-6; Granulin-7]
          Length = 591

 Score =  108 bits (271), Expect = 1e-23
 Identities = 54/157 (34%), Positives = 72/157 (45%)
 Frame = +1

Query: 73  ITPAFLERSNIINACQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTC 252
           + PA L  S I   C + ++ C D  TCC+  SG + CC  PNA+CC D +HCCP+ T C
Sbjct: 197 LLPAALPTSVI---CPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253

Query: 253 DLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCP 432
           DL   RC+ Q+                 ++P +T            VW+   C     CP
Sbjct: 254 DLRQSRCLSQNK----------AKTLLTKLPSWT------------VWDVE-CDQEVSCP 290

Query: 433 NSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
               CC L  G++ CCPFP  VCC     C P   +C
Sbjct: 291 EGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRC 327

 Score =  105 bits (261), Expect = 1e-22
 Identities = 56/149 (37%), Positives = 71/149 (47%), Gaps = 6/149 (4%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQ-SNE 291
           C  G+  C D  TCC    G   CC  P A CC D++HCCP G +CDLV+ RC+    + 
Sbjct: 112 CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSH 171

Query: 292 PIEWPVVKIVDPAKIEIPKYT-VERNPLRE---FIIKVWNKSTCPDG-SLCPNSFPCCLL 456
           P+   +     PA  +   YT  E  P+         +     CPD  S CP+   CCLL
Sbjct: 172 PLTTKL-----PA--QRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLL 224

Query: 457 APGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           A G+Y CCP P  +CCS    C P    C
Sbjct: 225 ASGEYGCCPMPNAICCSDHLHCCPQDTVC 253

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 47/140 (33%), Positives = 60/140 (42%)
 Frame = +1

Query: 130 ALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPV 309
           A C  ++TCC    GG  CCQ P+AVCC D  HCCP G TC++  + C            
Sbjct: 445 ASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC------------ 492

Query: 310 VKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFP 489
            K  D A +  P        + +          C D   C +   CC  + G + CCPF 
Sbjct: 493 EKAADGAHLAAPLAVGSTGGVMDV--------ACGDRHFCHDEQTCCRDSRGGWACCPFH 544

Query: 490 GGVCCSSPPGCVPSGQQCLS 549
            GVCC     C P+G  C S
Sbjct: 545 QGVCCKDQRHCCPAGFHCES 564

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 6/135 (4%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C + +TCC  +SG   CC +P AVCC D +HCCPE   C      C  Q    + W    
Sbjct: 289 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKT 347

Query: 316 IVDPAKIEIPK------YTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFC 477
              P++   P             PLR  I       +C +   C     CC LA G++ C
Sbjct: 348 PAQPSRPSQPSPPGPPGPPSPPGPLRSEI-------SCDEVVSCRPGNICCRLASGEWGC 400

Query: 478 CPFPGGVCCSSPPGC 522
           CP   G  C +   C
Sbjct: 401 CPSSEGYLCMAGERC 415

 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 40/144 (27%), Positives = 53/144 (36%), Gaps = 1/144 (0%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEP 294
           CQ+  A C    +C ++ +G   CC +  A+ CGD  HCCP G  C      CI + +  
Sbjct: 47  CQS-PANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQRPD-- 103

Query: 295 IEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSL-CPNSFPCCLLAPGQY 471
                                         I +     CP G   CP+S  CC +  G +
Sbjct: 104 ------------------------------IHLLGAVQCPGGEFECPDSSTCCHMLDGSW 133

Query: 472 FCCPFPGGVCCSSPPGCVPSGQQC 543
            CCP P   CC     C P G  C
Sbjct: 134 GCCPMPQASCCEDRVHCCPHGASC 157

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 23/62 (37%), Positives = 34/62 (54%)
 Frame = +1

Query: 103 IINACQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQ 282
           +++     +  C D++TCC    GG  CC +   VCC DQ HCCP G  C+    RC+H+
Sbjct: 513 VMDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHK 572

Query: 283 SN 288
            +
Sbjct: 573 KS 574

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 16/45 (35%), Positives = 19/45 (42%)
 Frame = +1

Query: 409 CPDGSLCPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           C   + CP    CC    G + CC  P  VCC     C P+G  C
Sbjct: 441 CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485

>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
           Granulin-2 (Granulin F); Granulin-3 (Granulin B)
           (Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
           Granulin-5 (Granulin C); Granulin-6 (Granulin D);
           Granulin-7 (Granulin E)]
          Length = 588

 Score =  108 bits (271), Expect = 1e-23
 Identities = 49/143 (34%), Positives = 65/143 (45%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEP 294
           C + K  C D  TCC   +G + CC  PNA+CC D +HCCP+ T CDL+  +CI +    
Sbjct: 206 CPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISKD--- 262

Query: 295 IEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYF 474
                         ++P Y V             N+  C     CP+ + CC L  G + 
Sbjct: 263 -------YTTDLMTKLPGYPV-------------NEVKCDLEVSCPDGYTCCRLNTGAWG 302

Query: 475 CCPFPGGVCCSSPPGCVPSGQQC 543
           CCPF   VCC     C P+G QC
Sbjct: 303 CCPFTKAVCCEDHIHCCPAGFQC 325

 Score =  103 bits (258), Expect = 3e-22
 Identities = 51/144 (35%), Positives = 66/144 (45%), Gaps = 1/144 (0%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEP 294
           C   +  C D  TCC+   G   CC  P A CC D++HCCP G +CDLV+ RCI  +   
Sbjct: 125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG-- 182

Query: 295 IEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDG-SLCPNSFPCCLLAPGQY 471
              P++K          K+  +R         V     CPD  + CP+   CC L  G+Y
Sbjct: 183 -THPLLK----------KFPAQRTNRAVASFSV----VCPDAKTQCPDDSTCCELPTGKY 227

Query: 472 FCCPFPGGVCCSSPPGCVPSGQQC 543
            CCP P  +CCS    C P    C
Sbjct: 228 GCCPMPNAICCSDHLHCCPQDTVC 251

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 47/141 (33%), Positives = 64/141 (45%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C D  TCC   +G   CC +  AVCC D +HCCP G  C      C       ++ P +K
Sbjct: 287 CPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMK 343

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
            V  A + +P   + +N +            C D S CP++  CC L+ G + CCP P  
Sbjct: 344 KVT-ASLSLPDPQILKNDV-----------PCDDFSSCPSNNTCCRLSSGDWGCCPMPEA 391

Query: 496 VCCSSPPGCVPSGQQCLSG*Y 558
           VCC     C P G +C+   Y
Sbjct: 392 VCCLDHQHCCPQGFKCMDEGY 412

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 46/136 (33%), Positives = 60/136 (44%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C   +TCC S  G   CCQ P+AVCC D+ HCCP G TC++  + C              
Sbjct: 447 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------- 492

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
                  E    +V+ +    F  KV N   C  G  C ++  CC  + G + CCP+  G
Sbjct: 493 -------EKDAGSVQPSMDLTFGSKVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKG 544

Query: 496 VCCSSPPGCVPSGQQC 543
           VCC     C P G  C
Sbjct: 545 VCCRDGRHCCPIGFHC 560

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 39/136 (28%), Positives = 54/136 (39%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C    TCC   SG   CC  P AVCC D  HCCP+G  C  +++    + +  +      
Sbjct: 369 CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC--MDEGYCQKGDRMVAG---- 422

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
                        +E+ P+R+  +       C   + CP    CC    G + CC  P  
Sbjct: 423 -------------LEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHA 469

Query: 496 VCCSSPPGCVPSGQQC 543
           VCC     C P+G  C
Sbjct: 470 VCCEDRQHCCPAGYTC 485

 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 37/136 (27%), Positives = 49/136 (36%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C D  +C ++ SG   CC +   V C D  HCCP G  C    K C   S+  +      
Sbjct: 67  CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL------ 120

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
                 ++ P    E                      CP+S  CC++  G + CCP P  
Sbjct: 121 ----GAVQCPGSQFE----------------------CPDSATCCIMIDGSWGCCPMPQA 154

Query: 496 VCCSSPPGCVPSGQQC 543
            CC     C P G  C
Sbjct: 155 SCCEDRVHCCPHGASC 170

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 24/65 (36%), Positives = 32/65 (49%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C D ++CC    GG  CC Y   VCC D  HCCP G  C     +C+ +      W ++ 
Sbjct: 522 CHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRKKTP--RWDIL- 578

Query: 316 IVDPA 330
           + DPA
Sbjct: 579 LRDPA 583

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 17/46 (36%), Positives = 20/46 (43%)
 Frame = +1

Query: 406 TCPDGSLCPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           +C     CP+ + C L   G   CCPF  GV C     C P G  C
Sbjct: 60  SCQIRDHCPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHC 105

>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
           cell-derived growth factor) (PCDGF) [Contains: Granulin
           1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
           Granulin 6; Granulin 7]
          Length = 589

 Score =  106 bits (265), Expect = 5e-23
 Identities = 48/143 (33%), Positives = 69/143 (48%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEP 294
           C + K  C D  TCC   +G + CC  PNA+CC D +HCCP+ T CDL+  +C+ ++   
Sbjct: 207 CPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN--- 263

Query: 295 IEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYF 474
                         ++P Y V+        +K   + +CP+G      + CC L  G + 
Sbjct: 264 -------YTTDLLTKLPGYPVKE-------VKCDMEVSCPEG------YTCCRLNTGAWG 303

Query: 475 CCPFPGGVCCSSPPGCVPSGQQC 543
           CCPF   VCC     C P+G QC
Sbjct: 304 CCPFAKAVCCEDHIHCCPAGFQC 326

 Score =  101 bits (252), Expect = 2e-21
 Identities = 48/144 (33%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEP 294
           C   +  C D  TCC+   G   CC  P A CC D++HCCP G +CDLV+ RC+  +   
Sbjct: 125 CPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG-- 182

Query: 295 IEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDG-SLCPNSFPCCLLAPGQY 471
                         + P     R     F +       CPD  + CP+   CC L  G+Y
Sbjct: 183 --------THTLLKKFPAQKTNRAVSLPFSV------VCPDAKTQCPDDSTCCELPTGKY 228

Query: 472 FCCPFPGGVCCSSPPGCVPSGQQC 543
            CCP P  +CCS    C P    C
Sbjct: 229 GCCPMPNAICCSDHLHCCPQDTVC 252

 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 46/141 (32%), Positives = 61/141 (43%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C +  TCC   +G   CC +  AVCC D +HCCP G  C      C       + W + K
Sbjct: 288 CPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTC-EMGILQVPW-MKK 345

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
           ++ P ++  P+      P             C D + CP +  CC L  G + CCP P  
Sbjct: 346 VIAPLRLPDPQILKSDTP-------------CDDFTRCPTNNTCCKLNSGDWGCCPIPEA 392

Query: 496 VCCSSPPGCVPSGQQCLSG*Y 558
           VCCS    C P G  CL+  Y
Sbjct: 393 VCCSDNQHCCPQGFTCLAQGY 413

 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 47/136 (34%), Positives = 64/136 (47%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C   +TCC S  G   CCQ P+AVCC D+ HCCP G TC++  + C  +  + I+ PV+ 
Sbjct: 448 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLL 506

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
            + P                    KV N   C +G  C ++  CC  + G + CCP+  G
Sbjct: 507 TLGP--------------------KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKG 545

Query: 496 VCCSSPPGCVPSGQQC 543
           VCC     C P G  C
Sbjct: 546 VCCRDGRHCCPGGFHC 561

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 47/136 (34%), Positives = 57/136 (41%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C    TCC   SG   CC  P AVCC D  HCCP+G TC L    C  Q  + +   + K
Sbjct: 370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC--QKGDTMVAGLEK 426

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
           I  PA+        +  PL+   I       C   + CP    CC    G + CC  P  
Sbjct: 427 I--PAR--------QTTPLQIGDI------GCDQHTSCPVGQTCCPSLKGSWACCQLPHA 470

Query: 496 VCCSSPPGCVPSGQQC 543
           VCC     C P+G  C
Sbjct: 471 VCCEDRQHCCPAGYTC 486

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 38/136 (27%), Positives = 51/136 (37%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C    +C ++ SG   CC +   V CGD  HCCP+G  C    K C   S+ P+      
Sbjct: 67  CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL------ 120

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
                 ++ P    E                      CP+S  CC++  G + CCP P  
Sbjct: 121 ----GAVQCPGSQFE----------------------CPDSATCCIMVDGSWGCCPMPQA 154

Query: 496 VCCSSPPGCVPSGQQC 543
            CC     C P G  C
Sbjct: 155 SCCEDRVHCCPHGASC 170

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 20/49 (40%), Positives = 25/49 (51%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQ 282
           C D +TCC   +G   CC Y   VCC D  HCCP G  C     +C+ +
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 17/46 (36%), Positives = 19/46 (41%)
 Frame = +1

Query: 406 TCPDGSLCPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           +C     CP  + C L   G   CCPF  GV C     C P G  C
Sbjct: 60  SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHC 105

>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
           Paragranulin; Granulin-1 (Granulin G); Granulin-2
           (Granulin F); Granulin-3 (Granulin B); Granulin-4
           (Granulin A); Granulin-5 (Granulin C); Granulin-6
           (Granulin D); Granulin-7 (Granulin E)]
          Length = 593

 Score =  106 bits (265), Expect = 5e-23
 Identities = 49/143 (34%), Positives = 69/143 (48%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEP 294
           C + ++ C D  TCC   SG + CC  PNA CC D +HCCP+ T CDL+  +C+ + N  
Sbjct: 208 CPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENAT 267

Query: 295 IEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYF 474
            +            ++P +TV         +K   + +CPDG      + CC L  G + 
Sbjct: 268 TD---------LLTKLPAHTVGD-------VKCDMEVSCPDG------YTCCRLQSGAWG 305

Query: 475 CCPFPGGVCCSSPPGCVPSGQQC 543
           CCPF   VCC     C P+G  C
Sbjct: 306 CCPFTQAVCCEDHIHCCPAGFTC 328

 Score =  104 bits (259), Expect = 2e-22
 Identities = 51/144 (35%), Positives = 64/144 (44%), Gaps = 1/144 (0%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEP 294
           C + +  C D  TCCV   G   CC  P A CC D++HCCP G  CDLV+ RCI  +   
Sbjct: 126 CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG-- 183

Query: 295 IEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDG-SLCPNSFPCCLLAPGQY 471
                     P   ++P     R       + + +   CPD  S CP+   CC L  G+Y
Sbjct: 184 --------THPLAKKLPAQRTNR------AVALSSSVMCPDARSRCPDGSTCCELPSGKY 229

Query: 472 FCCPFPGGVCCSSPPGCVPSGQQC 543
            CCP P   CCS    C P    C
Sbjct: 230 GCCPMPNATCCSDHLHCCPQDTVC 253

 Score =  100 bits (249), Expect = 3e-21
 Identities = 49/138 (35%), Positives = 63/138 (45%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C D  TCC  +SG   CC +  AVCC D +HCCP G TCD     C  Q    + W    
Sbjct: 290 CPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC-EQGPHQVPWMEKA 348

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYFCCPFPGG 495
              PA + +P     +  +            C + S CP+S  CC L  G++ CCP P  
Sbjct: 349 ---PAHLSLPDPQALKRDV-----------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEA 394

Query: 496 VCCSSPPGCVPSGQQCLS 549
           VCCS    C P G  C++
Sbjct: 395 VCCSDHQHCCPQGYTCVA 412

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 47/137 (34%), Positives = 63/137 (45%), Gaps = 1/137 (0%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVK 315
           C   +TCC S  G   CCQ P+AVCC D+ HCCP G TC++  + C        E  VV 
Sbjct: 450 CPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC--------EKEVVS 501

Query: 316 IVDPAKIEIPKYTVERNPLREFIIKVWNKST-CPDGSLCPNSFPCCLLAPGQYFCCPFPG 492
                    P   + R+P       V  K   C +G  C ++  CC      + CCP+  
Sbjct: 502 AQ-------PATFLARSP------HVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQ 548

Query: 493 GVCCSSPPGCVPSGQQC 543
           GVCC+    C P+G +C
Sbjct: 549 GVCCADRRHCCPAGFRC 565

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 46/143 (32%), Positives = 57/143 (39%)
 Frame = +1

Query: 115 CQNGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEP 294
           C N  + C    TCC   SG   CC  P AVCC D  HCCP+G TC +   +C   S   
Sbjct: 366 CDNVSS-CPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGS--- 420

Query: 295 IEWPVVKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLLAPGQYF 474
                 +IV           +E+ P R   +       C   + CP    CC    G + 
Sbjct: 421 ------EIVAG---------LEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWA 465

Query: 475 CCPFPGGVCCSSPPGCVPSGQQC 543
           CC  P  VCC     C P+G  C
Sbjct: 466 CCQLPHAVCCEDRQHCCPAGYTC 488

 Score = 77.0 bits (188), Expect = 4e-14
 Identities = 39/139 (28%), Positives = 49/139 (35%), Gaps = 1/139 (0%)
 Frame = +1

Query: 130 ALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPV 309
           A C    +C  + SG   CC +P AV CGD  HCCP G  C    + C  +S       +
Sbjct: 65  AHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI 124

Query: 310 VKIVDPAKIEIPKYTVERNPLREFIIKVWNKSTCPDGSL-CPNSFPCCLLAPGQYFCCPF 486
                                            CPD    CP+   CC++  G + CCP 
Sbjct: 125 --------------------------------QCPDSQFECPDFSTCCVMVDGSWGCCPM 152

Query: 487 PGGVCCSSPPGCVPSGQQC 543
           P   CC     C P G  C
Sbjct: 153 PQASCCEDRVHCCPHGAFC 171

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 5/112 (4%)
 Frame = +1

Query: 10  CCVSTQRFSIVTSILVQYIVSITPA-FLERSNIINA----CQNGKALCGDQKTCCVSKSG 174
           CC +    ++      + +VS  PA FL RS  +      C  G   C D +TCC     
Sbjct: 481 CCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGH-FCHDNQTCCRDNRQ 539

Query: 175 GHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPA 330
           G  CC Y   VCC D+ HCCP G  C     +C+ +  E   W    + DPA
Sbjct: 540 GWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR--EAPRWD-APLRDPA 588

 Score = 36.2 bits (82), Expect = 0.079
 Identities = 15/45 (33%), Positives = 16/45 (35%)
 Frame = +1

Query: 409 CPDGSLCPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           C   + C     C     G   CCPFP  V C     C P G  C
Sbjct: 61  CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHC 105

>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
          Length = 54

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 23/47 (48%), Positives = 28/47 (59%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCI 276
           C   +TCC +  G   CC Y   VCC D +HCCP GT CD  ++RCI
Sbjct: 7   CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 17/39 (43%), Positives = 20/39 (51%)
 Frame = +1

Query: 427 CPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           CP +  CC    G+  CCP+  GVCC     C PSG  C
Sbjct: 7   CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45

>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
          Length = 46

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 20/36 (55%), Positives = 22/36 (61%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEG 243
           C D +TCC +  GG  CC Y   VCC DQ HCCP G
Sbjct: 10  CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 16/42 (38%), Positives = 21/42 (50%)
 Frame = +1

Query: 409 CPDGSLCPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSG 534
           C +G  C +   CC  + G   CCP+  GVCC+    C P G
Sbjct: 4   CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45

>sp|P81013|GRN1_CYPCA Granulin-1
          Length = 57

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 19/48 (39%), Positives = 25/48 (52%)
 Frame = +1

Query: 133 LCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCI 276
           +C D  TCC+S  G   CC +    CC D +HCC  G  CD  +  C+
Sbjct: 9   ICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 17/45 (37%), Positives = 22/45 (48%)
 Frame = +1

Query: 409 CPDGSLCPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           C   ++CP+   CCL   G ++CCPF  G CC     C   G  C
Sbjct: 4   CDAATICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48

>sp|P81014|GRN2_CYPCA Granulin-2
          Length = 57

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 19/52 (36%), Positives = 24/52 (46%)
 Frame = +1

Query: 121 NGKALCGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCI 276
           N +  C  + TCC S  G   CC +    CC D  HCC  G  CD  +  C+
Sbjct: 5   NARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 16/45 (35%), Positives = 21/45 (46%)
 Frame = +1

Query: 409 CPDGSLCPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           C   + CP+   CC    G ++CCPF  G CC     C   G +C
Sbjct: 4   CNARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48

>sp|P81015|GRN3_CYPCA Granulin-3
          Length = 57

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 18/47 (38%), Positives = 21/47 (44%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCI 276
           C    TCC S  G   CC +    CC D  HCC  G  CD  +  C+
Sbjct: 10  CPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 17/45 (37%), Positives = 20/45 (44%)
 Frame = +1

Query: 409 CPDGSLCPNSFPCCLLAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 543
           C  G  CP+   CC    G ++CCPF  G CC     C   G  C
Sbjct: 4   CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48

>sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (RD21)
          Length = 462

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 22/66 (33%), Positives = 25/66 (37%), Gaps = 6/66 (9%)
 Frame = +1

Query: 136 CGDQKTCCVSKSGGHQC-----CQYPNAVCCGDQMHCCP-EGTTCDLVNKRCIHQSNEPI 297
           C +  TCC     G  C     C    A CC D   CCP E   CDL    C+   N P 
Sbjct: 381 CPESNTCCCLFEYGKYCFAWGCCPLEAATCCDDNYSCCPHEYPVCDLDQGTCLLSKNSPF 440

Query: 298 EWPVVK 315
               +K
Sbjct: 441 SVKALK 446

 Score = 36.6 bits (83), Expect = 0.061
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 4/45 (8%)
 Frame = +1

Query: 406 TCPDGSLCPNSFPCCLLAPGQYF----CCPFPGGVCCSSPPGCVP 528
           TCP+ + C     CCL   G+Y     CCP     CC     C P
Sbjct: 380 TCPESNTC-----CCLFEYGKYCFAWGCCPLEAATCCDDNYSCCP 419

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,260,404
Number of Sequences: 369166
Number of extensions: 1948029
Number of successful extensions: 6279
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5310
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6136
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5608903050
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

1. Dr_sW_006_P06
2. Dr_sW_016_B12
3. Dr_sW_003_M06
4. Dr_sW_023_F01
5. Dr_sW_022_H23
6. Dr_sW_012_G20