Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_M06
(486 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 89 5e-18
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 87 2e-17
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 87 2e-17
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 87 3e-17
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 51 2e-06
sp|P81013|GRN1_CYPCA Granulin-1 46 4e-05
sp|P81015|GRN3_CYPCA Granulin-3 43 3e-04
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 43 3e-04
sp|P25776|ORYA_ORYSA Oryzain alpha chain precursor 42 0.001
sp|P81014|GRN2_CYPCA Granulin-2 41 0.002
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 89.0 bits (219), Expect = 5e-18
Identities = 40/120 (33%), Positives = 53/120 (44%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC PNA+CC D +HCCP+ T CDL+ +CI + ++P Y V
Sbjct: 229 CCPMPNAICCSDHLHCCPQDTVCDLIQSKCISKD----------YTTDLMTKLPGYPV-- 276
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
N+ C CP+ + CC G + CCPF VCC C P+G QC
Sbjct: 277 -----------NEVKCDLEVSCPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQC 325
Score = 87.0 bits (214), Expect = 2e-17
Identities = 43/121 (35%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC P A CC D++HCCP G +CDLV+ RCI + P++K K+ +R
Sbjct: 148 CCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG---THPLLK----------KFPAQR 194
Query: 192 NPLREFIIKVWNKSTCPDG-SLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQ 368
V CPD + CP+ CC G+Y CCP P +CCS C P
Sbjct: 195 TNRAVASFSV----VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTV 250
Query: 369 C 371
C
Sbjct: 251 C 251
Score = 79.0 bits (193), Expect = 6e-15
Identities = 40/125 (32%), Positives = 56/125 (44%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC + AVCC D +HCCP G C C ++ P +K V A + +P + +
Sbjct: 303 CCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMKKVT-ASLSLPDPQILK 358
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
N + C D S CP++ CC + G + CCP P VCC C P G +C
Sbjct: 359 NDV-----------PCDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC 407
Query: 372 LSG*Y 386
+ Y
Sbjct: 408 MDEGY 412
Score = 74.7 bits (182), Expect = 1e-13
Identities = 40/120 (33%), Positives = 53/120 (44%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CCQ P+AVCC D+ HCCP G TC++ + C E +V+
Sbjct: 463 CCQLPHAVCCEDRQHCCPAGYTCNVKARTC---------------------EKDAGSVQP 501
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
+ F KV N C G C ++ CC + G + CCP+ GVCC C P G C
Sbjct: 502 SMDLTFGSKVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHC 560
Score = 67.4 bits (163), Expect = 2e-11
Identities = 33/120 (27%), Positives = 48/120 (40%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC P AVCC D HCCP+G C +++ + + + +E+
Sbjct: 385 CCPMPEAVCCLDHQHCCPQGFKC--MDEGYCQKGDRMVAG-----------------LEK 425
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
P+R+ + C + CP CC G + CC P VCC C P+G C
Sbjct: 426 MPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 485
Score = 62.4 bits (150), Expect = 5e-10
Identities = 32/121 (26%), Positives = 38/121 (31%), Gaps = 1/121 (0%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC + V C D HCCP G C K C S+ +
Sbjct: 83 CCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL---------------------- 120
Query: 192 NPLREFIIKVWNKSTCPDGSL-CPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQ 368
CP CP+S CC+ G + CCP P CC C P G
Sbjct: 121 -----------GAVQCPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGAS 169
Query: 369 C 371
C
Sbjct: 170 C 170
Score = 44.3 bits (103), Expect = 2e-04
Identities = 19/52 (36%), Positives = 25/52 (48%)
Frame = +3
Query: 3 GHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPA 158
G CC Y VCC D HCCP G C +C+ + W ++ + DPA
Sbjct: 535 GWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRKKTP--RWDIL-LRDPA 583
Score = 42.0 bits (97), Expect = 8e-04
Identities = 17/46 (36%), Positives = 20/46 (43%)
Frame = +3
Query: 234 TCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
+C CP+ + C L G CCPF GV C C P G C
Sbjct: 60 SCQIRDHCPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHC 105
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 87.4 bits (215), Expect = 2e-17
Identities = 46/129 (35%), Positives = 58/129 (44%), Gaps = 9/129 (6%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIP----KY 179
CC P A CC D++HCCP G +CDLV+ RC+ P ++P Y
Sbjct: 135 CCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGS----------HPLTTKLPAQRTNY 184
Query: 180 T-VERNPLRE---FIIKVWNKSTCPDG-SLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPP 344
T E P+ + CPD S CP+ CCL A G+Y CCP P +CCS
Sbjct: 185 TGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHL 244
Query: 345 GCVPSGQQC 371
C P C
Sbjct: 245 HCCPQDTVC 253
Score = 86.7 bits (213), Expect = 3e-17
Identities = 40/120 (33%), Positives = 52/120 (43%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC PNA+CC D +HCCP+ T CDL RC+ Q+ ++P +T
Sbjct: 231 CCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK----------AKTLLTKLPSWT--- 277
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
VW+ C CP CC G++ CCPFP VCC C P +C
Sbjct: 278 ---------VWDVE-CDQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRC 327
Score = 79.0 bits (193), Expect = 6e-15
Identities = 41/125 (32%), Positives = 52/125 (41%)
Frame = +3
Query: 3 GHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYT 182
G CCQ P+AVCC D HCCP G TC++ + C K D A + P
Sbjct: 460 GWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC------------EKAADGAHLAAPLAV 507
Query: 183 VERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSG 362
+ + C D C + CC + G + CCPF GVCC C P+G
Sbjct: 508 GSTGGVMDV--------ACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAG 559
Query: 363 QQCLS 377
C S
Sbjct: 560 FHCES 564
Score = 65.5 bits (158), Expect = 6e-11
Identities = 34/121 (28%), Positives = 41/121 (33%), Gaps = 1/121 (0%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC + A+ CGD HCCP G C CI + +
Sbjct: 69 CCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQRPD------------------------- 103
Query: 192 NPLREFIIKVWNKSTCPDGSL-CPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQ 368
I + CP G CP+S CC G + CCP P CC C P G
Sbjct: 104 -------IHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGAS 156
Query: 369 C 371
C
Sbjct: 157 C 157
Score = 59.7 bits (143), Expect = 3e-09
Identities = 35/119 (29%), Positives = 45/119 (37%), Gaps = 6/119 (5%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPK----- 176
CC +P AVCC D +HCCPE C C Q + W P++ P
Sbjct: 305 CCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKTPAQPSRPSQPSPPGPP 363
Query: 177 -YTVERNPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGC 350
PLR I +C + C CC A G++ CCP G C + C
Sbjct: 364 GPPSPPGPLRSEI-------SCDEVVSCRPGNICCRLASGEWGCCPSSEGYLCMAGERC 415
Score = 50.1 bits (118), Expect = 3e-06
Identities = 17/38 (44%), Positives = 22/38 (57%)
Frame = +3
Query: 3 GHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSN 116
G CC + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 537 GWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
Score = 40.8 bits (94), Expect = 0.002
Identities = 16/45 (35%), Positives = 19/45 (42%)
Frame = +3
Query: 237 CPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
C + CP CC G + CC P VCC C P+G C
Sbjct: 441 CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 37.7 bits (86), Expect = 0.014
Identities = 16/45 (35%), Positives = 18/45 (40%)
Frame = +3
Query: 237 CPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
C + CP C L A G CCPF + C C P G C
Sbjct: 47 CQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHC 91
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 87.0 bits (214), Expect = 2e-17
Identities = 42/121 (34%), Positives = 53/121 (43%), Gaps = 1/121 (0%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC P A CC D++HCCP G CDLV+ RCI + P ++P R
Sbjct: 149 CCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG----------THPLAKKLPAQRTNR 198
Query: 192 NPLREFIIKVWNKSTCPDG-SLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQ 368
+ + + CPD S CP+ CC G+Y CCP P CCS C P
Sbjct: 199 ------AVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTV 252
Query: 369 C 371
C
Sbjct: 253 C 253
Score = 87.0 bits (214), Expect = 2e-17
Identities = 40/120 (33%), Positives = 56/120 (46%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC PNA CC D +HCCP+ T CDL+ +C+ + N + ++P +TV
Sbjct: 231 CCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD---------LLTKLPAHTVGD 281
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
+K + +CPDG + CC G + CCPF VCC C P+G C
Sbjct: 282 -------VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTC 328
Score = 85.9 bits (211), Expect = 5e-17
Identities = 41/122 (33%), Positives = 54/122 (44%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC + AVCC D +HCCP G TCD C Q + W PA + +P +
Sbjct: 306 CCPFTQAVCCEDHIHCCPAGFTCDTQKGTC-EQGPHQVPWMEKA---PAHLSLPDPQALK 361
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
+ C + S CP+S CC G++ CCP P VCCS C P G C
Sbjct: 362 RDV-----------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC 410
Query: 372 LS 377
++
Sbjct: 411 VA 412
Score = 72.8 bits (177), Expect = 4e-13
Identities = 41/121 (33%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CCQ P+AVCC D+ HCCP G TC++ + C E VV P + R
Sbjct: 466 CCQLPHAVCCEDRQHCCPAGYTCNVKARSC--------EKEVVSAQ-------PATFLAR 510
Query: 192 NPLREFIIKVWNKST-CPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQ 368
+P V K C +G C ++ CC + CCP+ GVCC+ C P+G +
Sbjct: 511 SP------HVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFR 564
Query: 369 C 371
C
Sbjct: 565 C 565
Score = 70.1 bits (170), Expect = 3e-12
Identities = 38/120 (31%), Positives = 48/120 (40%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC P AVCC D HCCP+G TC + +C S +IV +E+
Sbjct: 388 CCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGS---------EIVAG---------LEK 428
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
P R + C + CP CC G + CC P VCC C P+G C
Sbjct: 429 MPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 68.9 bits (167), Expect = 6e-12
Identities = 34/121 (28%), Positives = 41/121 (33%), Gaps = 1/121 (0%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC +P AV CGD HCCP G C + C +S +
Sbjct: 83 CCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI------------------ 124
Query: 192 NPLREFIIKVWNKSTCPDGSL-CPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQ 368
CPD CP+ CC+ G + CCP P CC C P G
Sbjct: 125 --------------QCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAF 170
Query: 369 C 371
C
Sbjct: 171 C 171
Score = 45.1 bits (105), Expect = 9e-05
Identities = 20/52 (38%), Positives = 25/52 (48%)
Frame = +3
Query: 3 GHQCCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPA 158
G CC Y VCC D+ HCCP G C +C+ + E W + DPA
Sbjct: 540 GWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR--EAPRWD-APLRDPA 588
Score = 35.8 bits (81), Expect = 0.054
Identities = 15/45 (33%), Positives = 16/45 (35%)
Frame = +3
Query: 237 CPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
C + C C G CCPFP V C C P G C
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHC 105
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 86.7 bits (213), Expect = 3e-17
Identities = 39/120 (32%), Positives = 57/120 (47%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC PNA+CC D +HCCP+ T CDL+ +C+ ++ ++P Y V+
Sbjct: 230 CCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN----------YTTDLLTKLPGYPVKE 279
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
+K + +CP+G + CC G + CCPF VCC C P+G QC
Sbjct: 280 -------VKCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC 326
Score = 84.3 bits (207), Expect = 1e-16
Identities = 40/121 (33%), Positives = 52/121 (42%), Gaps = 1/121 (0%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC P A CC D++HCCP G +CDLV+ RC+ + + P R
Sbjct: 148 CCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG----------THTLLKKFPAQKTNR 197
Query: 192 NPLREFIIKVWNKSTCPDG-SLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQ 368
F + CPD + CP+ CC G+Y CCP P +CCS C P
Sbjct: 198 AVSLPFSV------VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTV 251
Query: 369 C 371
C
Sbjct: 252 C 252
Score = 82.0 bits (201), Expect = 7e-16
Identities = 40/125 (32%), Positives = 53/125 (42%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC + AVCC D +HCCP G C C + W + K++ P ++ P+
Sbjct: 304 CCPFAKAVCCEDHIHCCPAGFQCHTEKGTC-EMGILQVPW-MKKVIAPLRLPDPQILKSD 361
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
P C D + CP + CC G + CCP P VCCS C P G C
Sbjct: 362 TP-------------CDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC 408
Query: 372 LSG*Y 386
L+ Y
Sbjct: 409 LAQGY 413
Score = 80.1 bits (196), Expect = 2e-15
Identities = 41/120 (34%), Positives = 57/120 (47%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CCQ P+AVCC D+ HCCP G TC++ + C + + I+ PV+ + P
Sbjct: 464 CCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLLTLGP------------ 510
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
KV N C +G C ++ CC + G + CCP+ GVCC C P G C
Sbjct: 511 --------KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHC 561
Score = 71.6 bits (174), Expect = 9e-13
Identities = 34/120 (28%), Positives = 43/120 (35%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC + V CGD HCCP+G C K C S+ P+ ++ P E
Sbjct: 83 CCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL----------GAVQCPGSQFE- 131
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
CP+S CC+ G + CCP P CC C P G C
Sbjct: 132 ---------------------CPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 69.7 bits (169), Expect = 3e-12
Identities = 41/120 (34%), Positives = 52/120 (43%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQSNEPIEWPVVKIVDPAKIEIPKYTVER 191
CC P AVCC D HCCP+G TC L C Q + + + KI PA+ +
Sbjct: 386 CCPIPEAVCCSDNQHCCPQGFTC-LAQGYC--QKGDTMVAGLEKI--PAR--------QT 432
Query: 192 NPLREFIIKVWNKSTCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
PL+ I ++CP G C C G + CC P VCC C P+G C
Sbjct: 433 TPLQIGDIGCDQHTSCPVGQTC------CPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486
Score = 41.2 bits (95), Expect = 0.001
Identities = 17/46 (36%), Positives = 19/46 (41%)
Frame = +3
Query: 234 TCPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
+C CP + C L G CCPF GV C C P G C
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHC 105
Score = 41.2 bits (95), Expect = 0.001
Identities = 14/33 (42%), Positives = 17/33 (51%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCIHQ 110
CC Y VCC D HCCP G C +C+ +
Sbjct: 539 CCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 50.8 bits (120), Expect = 2e-06
Identities = 18/31 (58%), Positives = 21/31 (67%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCI 104
CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 23 CCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 44.7 bits (104), Expect = 1e-04
Identities = 17/39 (43%), Positives = 20/39 (51%)
Frame = +3
Query: 255 CPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
CP + CC G+ CCP+ GVCC C PSG C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 46.2 bits (108), Expect = 4e-05
Identities = 17/45 (37%), Positives = 22/45 (48%)
Frame = +3
Query: 237 CPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
C ++CP+ CCL G ++CCPF G CC C G C
Sbjct: 4 CDAATICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 37.7 bits (86), Expect = 0.014
Identities = 12/31 (38%), Positives = 16/31 (51%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCI 104
CC + CC D +HCC G CD + C+
Sbjct: 26 CCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 43.1 bits (100), Expect = 3e-04
Identities = 17/45 (37%), Positives = 20/45 (44%)
Frame = +3
Query: 237 CPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
C G CP+ CC G ++CCPF G CC C G C
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 35.4 bits (80), Expect = 0.070
Identities = 12/31 (38%), Positives = 15/31 (48%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCI 104
CC + CC D HCC G CD + C+
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 43.1 bits (100), Expect = 3e-04
Identities = 16/42 (38%), Positives = 21/42 (50%)
Frame = +3
Query: 237 CPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSG 362
C +G C + CC + G CCP+ GVCC+ C P G
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45
Score = 41.6 bits (96), Expect = 0.001
Identities = 14/23 (60%), Positives = 14/23 (60%)
Frame = +3
Query: 3 GHQCCQYPNAVCCGDQMHCCPEG 71
G CC Y VCC DQ HCCP G
Sbjct: 23 GXACCPYSQGVCCADQRHCCPVG 45
>sp|P25776|ORYA_ORYSA Oryzain alpha chain precursor
Length = 458
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Frame = +3
Query: 225 NKSTCPDGSLCPNSFPCCLFAPGQYF----CCPFPGGVCCSSPPGCVP 356
N TCPD + C CC++ G+Y CCP G CC C P
Sbjct: 369 NYYTCPDSTTC-----CCIYEYGKYCYAWGCCPLEGATCCDDHYSCCP 411
Score = 34.7 bits (78), Expect = 0.12
Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 1/45 (2%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCP-EGTTCDLVNKRCIHQSNEPIEWPVVK 143
CC A CC D CCP E C++ C+ + P+ +K
Sbjct: 394 CCPLEGATCCDDHYSCCPHEYPICNVQQGTCLMAKDSPLAVKALK 438
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 40.8 bits (94), Expect = 0.002
Identities = 16/45 (35%), Positives = 21/45 (46%)
Frame = +3
Query: 237 CPDGSLCPNSFPCCLFAPGQYFCCPFPGGVCCSSPPGCVPSGQQC 371
C + CP+ CC G ++CCPF G CC C G +C
Sbjct: 4 CNARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
Score = 35.8 bits (81), Expect = 0.054
Identities = 12/31 (38%), Positives = 15/31 (48%)
Frame = +3
Query: 12 CCQYPNAVCCGDQMHCCPEGTTCDLVNKRCI 104
CC + CC D HCC G CD + C+
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,433,538
Number of Sequences: 369166
Number of extensions: 1446472
Number of successful extensions: 4864
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4310
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4784
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2921208590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)