Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00088 (677 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q16795|NUEM_HUMAN NADH-ubiquinone oxidoreductase 39 kDa ... 101 2e-21 sp|P34943|NUEM_BOVIN NADH-ubiquinone oxidoreductase 39 kDa ... 99 8e-21 sp|Q9DC69|NUEM_MOUSE NADH-ubiquinone oxidoreductase 39 kDa ... 94 3e-19 sp|P25284|NUEM_NEUCR NADH-ubiquinone oxidoreductase 40 kDa ... 42 0.001 sp|P25811|TRME_BACSU Probable tRNA modification GTPase trmE 34 0.31 sp|Q01008|VP23_SHV21 Probable capsid protein VP23 (Gene 26 ... 34 0.40 sp|P27169|PON1_HUMAN Serum paraoxonase/arylesterase 1 (PON ... 31 2.6 sp|O66841|NUOF_AQUAE NADH-quinone oxidoreductase chain F (N... 31 3.4 sp|Q8RFJ8|SYA_FUSNN Alanyl-tRNA synthetase (Alanine--tRNA l... 30 4.4 sp|Q9RCA7|TRME_BACHD Probable tRNA modification GTPase trmE 30 5.8
>sp|Q16795|NUEM_HUMAN NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial precursor (Complex I-39KD) (CI-39KD) Length = 377 Score = 101 bits (251), Expect = 2e-21 Identities = 77/208 (37%), Positives = 104/208 (50%), Gaps = 2/208 (0%) Frame = +2 Query: 8 STFLKTKGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKY 187 S +L+ K +GE V FPEA+I +P+D++G D F R GP IP+ Sbjct: 178 SRYLRNKAVGEKVVRDAFPEAIIVKPSDIFGREDRFLNSFASMHR---FGP---IPLGSL 231 Query: 188 GKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLRFKPEKL 367 G KT KQPV DV+KGI+N V DP + VGP RY L HL+ +++ V +L Sbjct: 232 GWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFAFVGPSRYLLFHLVKYIFAV----AHRL 287 Query: 368 VISNMDPLLKLQ-VKIMETIKPIYPIVCLDKLERECFTD-TLNDLPTLEDIGVDNLTNLE 541 + PL + V + I P P + DK+ER TD L LP LED+G+ T LE Sbjct: 288 FLPFPLPLFAYRWVARVFEISPFEPWITRDKVERMHITDMKLPHLPGLEDLGI-QATPLE 346 Query: 542 DRLFYEIRFRREDLYYWDSVGEIATIPP 625 + + RR Y W S EI + P Sbjct: 347 LKAIEVL--RRHRTYRWLS-AEIEDVKP 371
>sp|P34943|NUEM_BOVIN NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial precursor (Complex I-39KD) (CI-39KD) Length = 380 Score = 99.4 bits (246), Expect = 8e-21 Identities = 79/211 (37%), Positives = 103/211 (48%), Gaps = 5/211 (2%) Frame = +2 Query: 8 STFLKTKGIGELEVLREFPEAVIFRPADMYGHNDHFFFYL--MRWERRRFMGPKSYIPIW 181 S +L++K +GE EV FPEA I +PA+++G D F Y +RW F G +P+ Sbjct: 178 SKYLRSKAVGEKEVRETFPEATIIKPAEIFGREDRFLNYFANIRW----FGG----VPLI 229 Query: 182 KYGKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLR--FK 355 GKKT KQPV DV KGIIN + DP VGP RY L L+ +++ V F Sbjct: 230 SLGKKTVKQPVYIVDVTKGIINAIKDPDARGKTFAFVGPSRYLLFDLVQYVFAVAHRPFL 289 Query: 356 PEKLVISNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTD-TLNDLPTLEDIGVDNLT 532 P L + + I P P DK+ER TD L LP LED+GV+ T Sbjct: 290 PYPL-----PHFAYRWIGRLFEISPFEPWTTRDKVERIHTTDKILPHLPGLEDLGVE-AT 343 Query: 533 NLEDRLFYEIRFRREDLYYWDSVGEIATIPP 625 LE + + RR Y W S EI + P Sbjct: 344 PLELKAIEVL--RRHRTYRWLS-SEIEDVQP 371
>sp|Q9DC69|NUEM_MOUSE NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial precursor (Complex I-39KD) (CI-39KD) Length = 377 Score = 94.0 bits (232), Expect = 3e-19 Identities = 70/198 (35%), Positives = 99/198 (50%), Gaps = 3/198 (1%) Frame = +2 Query: 8 STFLKTKGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKY 187 S L++K +GE EV FPEA+I RP+D++G D F + + R F+ +P+ Sbjct: 178 SKSLRSKAVGEKEVRSVFPEAIIIRPSDIFGREDRFLNHFANY--RWFLA----VPLVSL 231 Query: 188 GKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLR--FKPE 361 G KT KQPV DV+KGI+N DP GP+RY L HL+ +++ + F P Sbjct: 232 GFKTVKQPVYVADVSKGIVNATKDPDAVGKTFAFTGPNRYLLFHLVKYIFGMTHRTFIPY 291 Query: 362 KLVISNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTDTL-NDLPTLEDIGVDNLTNL 538 L + + KL + P P DK+ER +D + DLP LED+GV T L Sbjct: 292 PLPLFVYSWIGKL-----FGLSPFEPWTTKDKVERIHISDVMPTDLPGLEDLGVQP-TPL 345 Query: 539 EDRLFYEIRFRREDLYYW 592 E + + RR Y W Sbjct: 346 ELKSIEVL--RRHRTYRW 361
>sp|P25284|NUEM_NEUCR NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial precursor (Complex I-40KD) (CI-40KD) Length = 375 Score = 42.0 bits (97), Expect = 0.001 Identities = 44/199 (22%), Positives = 81/199 (40%), Gaps = 7/199 (3%) Frame = +2 Query: 14 FLKTKGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKYGK 193 F TK GE V FPE I RPA M+G D L + + G Sbjct: 177 FFATKARGEQVVRSIFPETTIVRPAPMFGFEDRLLHKLASVKN----------ILTSNGM 226 Query: 194 KTFKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLRFKPEKLVI 373 + PV DV + + ++ D + E GP Y + + + +K + V Sbjct: 227 QEKYNPVHVIDVGQALEQMLWDDNTASETFELYGPKTYTTAEISEMVDREI-YKRRRHV- 284 Query: 374 SNMDPLLKLQVKIMETIKPI------YPIVCLDKLERECFTDTLN-DLPTLEDIGVDNLT 532 + KI++ I + +PI+ D++ERE ++ + T +D+G++ Sbjct: 285 -------NVPKKILKPIAGVLNKALWWPIMSADEIEREFHDQVIDPEAKTFKDLGIEP-A 336 Query: 533 NLEDRLFYEIRFRREDLYY 589 ++ + ++ ++ R + YY Sbjct: 337 DIANFTYHYLQSYRSNAYY 355
>sp|P25811|TRME_BACSU Probable tRNA modification GTPase trmE Length = 459 Score = 34.3 bits (77), Expect = 0.31 Identities = 43/174 (24%), Positives = 76/174 (43%), Gaps = 14/174 (8%) Frame = +2 Query: 197 TFKQPVAGYDVAKGI-INVVNDPTISET--IIEAVGPHRYRLDHLIWWLYMVLRFKPEKL 367 T + + Y +G+ + +V+ I ET I+E +G R R ++ ++L L Sbjct: 255 TTRDVIEEYVNVRGVPLRLVDTAGIRETEDIVERIGVERSR--QVLKEADLIL------L 306 Query: 368 VISNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTDT------LNDLPT-----LEDI 514 V++ + L + VK+ E ++ + IV L+K + E DT N P L++ Sbjct: 307 VLNYSEELSEEDVKLFEAVEGMDVIVILNKTDLEPKIDTERVRELANGRPVVTTSLLKEE 366 Query: 515 GVDNLTNLEDRLFYEIRFRREDLYYWDSVGEIATIPPPPRAVI*DL*SININIP 676 G+++L LFY DL Y + I + RA+ L I ++P Sbjct: 367 GINDLEEAIQSLFYTGAIESGDLTYVSNTRHITILQQAKRAIEDALSGIEQDVP 420
>sp|Q01008|VP23_SHV21 Probable capsid protein VP23 (Gene 26 protein) Length = 304 Score = 33.9 bits (76), Expect = 0.40 Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 19/100 (19%) Frame = +2 Query: 383 DPLLKLQVKIMETIKPI---YPIVCLDKL------ERECFTDTLN--------DLPTLED 511 D + KLQ KI +I P+ + + LD L R+ F D ++ L LE+ Sbjct: 18 DEITKLQKKI-GSILPLQDPHKLQSLDTLGLNAVCSRDVFPDYVHMFSYLSKCTLAILEE 76 Query: 512 IGVDNL--TNLEDRLFYEIRFRREDLYYWDSVGEIATIPP 625 + DNL T L+ Y+I+ E ++ WD + IPP Sbjct: 77 VNPDNLILTRLDPSETYQIKNVYEPMFQWDGFSNLTVIPP 116
>sp|P27169|PON1_HUMAN Serum paraoxonase/arylesterase 1 (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1) (K-45) Length = 355 Score = 31.2 bits (69), Expect = 2.6 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Frame = +2 Query: 44 EVLREFPEAVIFRPADMYGHNDHFFF--YLMRWERRRFMGPKSYIPIWKYGKKTFKQPVA 217 ++L + V P YG NDH+F YL WE ++G ++ + Y + Sbjct: 162 KLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWE--MYLG-LAWSYVVYYSPSEVRVVAE 218 Query: 218 GYDVAKGI 241 G+D A GI Sbjct: 219 GFDFANGI 226
>sp|O66841|NUOF_AQUAE NADH-quinone oxidoreductase chain F (NADH dehydrogenase I, chain F) (NDH-1, chain F) Length = 426 Score = 30.8 bits (68), Expect = 3.4 Identities = 19/60 (31%), Positives = 27/60 (45%) Frame = +2 Query: 116 FFYLMRWERRRFMGPKSYIPIWKYGKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVG 295 F M WE R++GP Y G K F PV+G G+ + + T+ E I + G Sbjct: 229 FIISMGWEEYRYIGPSDYA-----GPKLF--PVSGKVKKPGVYELPMNTTLREVIFKYAG 281
>sp|Q8RFJ8|SYA_FUSNN Alanyl-tRNA synthetase (Alanine--tRNA ligase) (AlaRS) Length = 867 Score = 30.4 bits (67), Expect = 4.4 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 9/75 (12%) Frame = +2 Query: 389 LLKLQVKIMETIKPIYP--------IVCLDKLERECFTDTLNDLPTLEDIGVDN-LTNLE 541 + K+ K++E + YP I + K+E E F++TL+ L + +DN LTN + Sbjct: 322 MYKMVDKVVEKFEIAYPDLRKNVENIRKIVKIEEEKFSNTLDQGIQLVNQEIDNLLTNGK 381 Query: 542 DRLFYEIRFRREDLY 586 ++L EI F+ D Y Sbjct: 382 NKLDGEISFKLYDTY 396
>sp|Q9RCA7|TRME_BACHD Probable tRNA modification GTPase trmE Length = 458 Score = 30.0 bits (66), Expect = 5.8 Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 14/174 (8%) Frame = +2 Query: 197 TFKQPVAGYDVAKGI-INVVNDPTISET--IIEAVGPHRYRLDHLIWWLYMVLRFKPEKL 367 T + + Y +G+ + +V+ I ET I+E +G R R ++ ++L L Sbjct: 254 TTRDVIEEYVNVRGVPLRLVDTAGIRETEDIVERIGVERSR--EVLKEAELIL------L 305 Query: 368 VISNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTDTLN-----------DLPTLEDI 514 V++ + L K + E I + IV ++K + E D ++D Sbjct: 306 VLNFGEELSKEDEALFEAISGMEAIVIVNKTDVEQKIDLTRVRELAAGRPVITTSIVQDQ 365 Query: 515 GVDNLTNLEDRLFYEIRFRREDLYYWDSVGEIATIPPPPRAVI*DL*SININIP 676 G+D L LF+E D+ Y + IA + RAV L +I +++P Sbjct: 366 GIDELEAAIASLFFESGIESGDVTYVSNSRHIALLEQAKRAVEDALEAIEMDVP 419
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,047,191 Number of Sequences: 369166 Number of extensions: 1741171 Number of successful extensions: 4748 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4630 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4742 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 5733423530 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)