Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_E11
(677 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q16795|NUEM_HUMAN NADH-ubiquinone oxidoreductase 39 kDa ... 101 2e-21
sp|P34943|NUEM_BOVIN NADH-ubiquinone oxidoreductase 39 kDa ... 99 8e-21
sp|Q9DC69|NUEM_MOUSE NADH-ubiquinone oxidoreductase 39 kDa ... 94 3e-19
sp|P25284|NUEM_NEUCR NADH-ubiquinone oxidoreductase 40 kDa ... 42 0.001
sp|P25811|TRME_BACSU Probable tRNA modification GTPase trmE 35 0.18
sp|Q01008|VP23_SHV21 Probable capsid protein VP23 (Gene 26 ... 34 0.40
sp|P27169|PON1_HUMAN Serum paraoxonase/arylesterase 1 (PON ... 31 2.6
sp|Q9RCA7|TRME_BACHD Probable tRNA modification GTPase trmE 31 3.4
sp|O66841|NUOF_AQUAE NADH-quinone oxidoreductase chain F (N... 31 3.4
sp|Q8RFJ8|SYA_FUSNN Alanyl-tRNA synthetase (Alanine--tRNA l... 30 4.4
>sp|Q16795|NUEM_HUMAN NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial
precursor (Complex I-39KD) (CI-39KD)
Length = 377
Score = 101 bits (251), Expect = 2e-21
Identities = 77/208 (37%), Positives = 104/208 (50%), Gaps = 2/208 (0%)
Frame = +2
Query: 8 STFLKTKGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKY 187
S +L+ K +GE V FPEA+I +P+D++G D F R GP IP+
Sbjct: 178 SRYLRNKAVGEKVVRDAFPEAIIVKPSDIFGREDRFLNSFASMHR---FGP---IPLGSL 231
Query: 188 GKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLRFKPEKL 367
G KT KQPV DV+KGI+N V DP + VGP RY L HL+ +++ V +L
Sbjct: 232 GWKTVKQPVYVVDVSKGIVNAVKDPDANGKSFAFVGPSRYLLFHLVKYIFAV----AHRL 287
Query: 368 VISNMDPLLKLQ-VKIMETIKPIYPIVCLDKLERECFTD-TLNDLPTLEDIGVDNLTNLE 541
+ PL + V + I P P + DK+ER TD L LP LED+G+ T LE
Sbjct: 288 FLPFPLPLFAYRWVARVFEISPFEPWITRDKVERMHITDMKLPHLPGLEDLGI-QATPLE 346
Query: 542 DRLFYEIRFRREDLYYWDSVGEIATIPP 625
+ + RR Y W S EI + P
Sbjct: 347 LKAIEVL--RRHRTYRWLS-AEIEDVKP 371
>sp|P34943|NUEM_BOVIN NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial
precursor (Complex I-39KD) (CI-39KD)
Length = 380
Score = 99.4 bits (246), Expect = 8e-21
Identities = 79/211 (37%), Positives = 103/211 (48%), Gaps = 5/211 (2%)
Frame = +2
Query: 8 STFLKTKGIGELEVLREFPEAVIFRPADMYGHNDHFFFYL--MRWERRRFMGPKSYIPIW 181
S +L++K +GE EV FPEA I +PA+++G D F Y +RW F G +P+
Sbjct: 178 SKYLRSKAVGEKEVRETFPEATIIKPAEIFGREDRFLNYFANIRW----FGG----VPLI 229
Query: 182 KYGKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLR--FK 355
GKKT KQPV DV KGIIN + DP VGP RY L L+ +++ V F
Sbjct: 230 SLGKKTVKQPVYIVDVTKGIINAIKDPDARGKTFAFVGPSRYLLFDLVQYVFAVAHRPFL 289
Query: 356 PEKLVISNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTD-TLNDLPTLEDIGVDNLT 532
P L + + I P P DK+ER TD L LP LED+GV+ T
Sbjct: 290 PYPL-----PHFAYRWIGRLFEISPFEPWTTRDKVERIHTTDKILPHLPGLEDLGVE-AT 343
Query: 533 NLEDRLFYEIRFRREDLYYWDSVGEIATIPP 625
LE + + RR Y W S EI + P
Sbjct: 344 PLELKAIEVL--RRHRTYRWLS-SEIEDVQP 371
>sp|Q9DC69|NUEM_MOUSE NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial
precursor (Complex I-39KD) (CI-39KD)
Length = 377
Score = 94.0 bits (232), Expect = 3e-19
Identities = 70/198 (35%), Positives = 99/198 (50%), Gaps = 3/198 (1%)
Frame = +2
Query: 8 STFLKTKGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKY 187
S L++K +GE EV FPEA+I RP+D++G D F + + R F+ +P+
Sbjct: 178 SKSLRSKAVGEKEVRSVFPEAIIIRPSDIFGREDRFLNHFANY--RWFLA----VPLVSL 231
Query: 188 GKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLR--FKPE 361
G KT KQPV DV+KGI+N DP GP+RY L HL+ +++ + F P
Sbjct: 232 GFKTVKQPVYVADVSKGIVNATKDPDAVGKTFAFTGPNRYLLFHLVKYIFGMTHRTFIPY 291
Query: 362 KLVISNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTDTL-NDLPTLEDIGVDNLTNL 538
L + + KL + P P DK+ER +D + DLP LED+GV T L
Sbjct: 292 PLPLFVYSWIGKL-----FGLSPFEPWTTKDKVERIHISDVMPTDLPGLEDLGVQP-TPL 345
Query: 539 EDRLFYEIRFRREDLYYW 592
E + + RR Y W
Sbjct: 346 ELKSIEVL--RRHRTYRW 361
>sp|P25284|NUEM_NEUCR NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial
precursor (Complex I-40KD) (CI-40KD)
Length = 375
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/199 (22%), Positives = 81/199 (40%), Gaps = 7/199 (3%)
Frame = +2
Query: 14 FLKTKGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKYGK 193
F TK GE V FPE I RPA M+G D L + + G
Sbjct: 177 FFATKARGEQVVRSIFPETTIVRPAPMFGFEDRLLHKLASVKN----------ILTSNGM 226
Query: 194 KTFKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLRFKPEKLVI 373
+ PV DV + + ++ D + E GP Y + + + +K + V
Sbjct: 227 QEKYNPVHVIDVGQALEQMLWDDNTASETFELYGPKTYTTAEISEMVDREI-YKRRRHV- 284
Query: 374 SNMDPLLKLQVKIMETIKPI------YPIVCLDKLERECFTDTLN-DLPTLEDIGVDNLT 532
+ KI++ I + +PI+ D++ERE ++ + T +D+G++
Sbjct: 285 -------NVPKKILKPIAGVLNKALWWPIMSADEIEREFHDQVIDPEAKTFKDLGIEP-A 336
Query: 533 NLEDRLFYEIRFRREDLYY 589
++ + ++ ++ R + YY
Sbjct: 337 DIANFTYHYLQSYRSNAYY 355
>sp|P25811|TRME_BACSU Probable tRNA modification GTPase trmE
Length = 459
Score = 35.0 bits (79), Expect = 0.18
Identities = 43/174 (24%), Positives = 76/174 (43%), Gaps = 14/174 (8%)
Frame = +2
Query: 197 TFKQPVAGYDVAKGI-INVVNDPTISET--IIEAVGPHRYRLDHLIWWLYMVLRFKPEKL 367
T + + Y +G+ + +V+ I ET I+E +G R R ++ ++L L
Sbjct: 255 TTRDVIEEYVNVRGVPLRLVDTAGIRETEDIVERIGVERSR--QVLKEADLIL------L 306
Query: 368 VISNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTDT------LNDLPT-----LEDI 514
V++ + L + VK+ E ++ + IV L+K + E DT N P L++
Sbjct: 307 VLNYSEELSEEDVKLFEAVEGMDVIVILNKTDLEPKIDTERVRELANGRPVVTTSLLKEE 366
Query: 515 GVDNLTNLEDRLFYEIRFRREDLYYWDSVGEIATIPPPPRAVI*DLYSININIP 676
G+++L LFY DL Y + I + RA+ L I ++P
Sbjct: 367 GINDLEEAIQSLFYTGAIESGDLTYVSNTRHITILQQAKRAIEDALSGIEQDVP 420
>sp|Q01008|VP23_SHV21 Probable capsid protein VP23 (Gene 26 protein)
Length = 304
Score = 33.9 bits (76), Expect = 0.40
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 19/100 (19%)
Frame = +2
Query: 383 DPLLKLQVKIMETIKPI---YPIVCLDKL------ERECFTDTLN--------DLPTLED 511
D + KLQ KI +I P+ + + LD L R+ F D ++ L LE+
Sbjct: 18 DEITKLQKKI-GSILPLQDPHKLQSLDTLGLNAVCSRDVFPDYVHMFSYLSKCTLAILEE 76
Query: 512 IGVDNL--TNLEDRLFYEIRFRREDLYYWDSVGEIATIPP 625
+ DNL T L+ Y+I+ E ++ WD + IPP
Sbjct: 77 VNPDNLILTRLDPSETYQIKNVYEPMFQWDGFSNLTVIPP 116
>sp|P27169|PON1_HUMAN Serum paraoxonase/arylesterase 1 (PON 1) (Serum
aryldialkylphosphatase 1) (A-esterase 1) (Aromatic
esterase 1) (K-45)
Length = 355
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Frame = +2
Query: 44 EVLREFPEAVIFRPADMYGHNDHFFF--YLMRWERRRFMGPKSYIPIWKYGKKTFKQPVA 217
++L + V P YG NDH+F YL WE ++G ++ + Y +
Sbjct: 162 KLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWE--MYLG-LAWSYVVYYSPSEVRVVAE 218
Query: 218 GYDVAKGI 241
G+D A GI
Sbjct: 219 GFDFANGI 226
>sp|Q9RCA7|TRME_BACHD Probable tRNA modification GTPase trmE
Length = 458
Score = 30.8 bits (68), Expect = 3.4
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 14/174 (8%)
Frame = +2
Query: 197 TFKQPVAGYDVAKGI-INVVNDPTISET--IIEAVGPHRYRLDHLIWWLYMVLRFKPEKL 367
T + + Y +G+ + +V+ I ET I+E +G R R ++ ++L L
Sbjct: 254 TTRDVIEEYVNVRGVPLRLVDTAGIRETEDIVERIGVERSR--EVLKEAELIL------L 305
Query: 368 VISNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTDTLN-----------DLPTLEDI 514
V++ + L K + E I + IV ++K + E D ++D
Sbjct: 306 VLNFGEELSKEDEALFEAISGMEAIVIVNKTDVEQKIDLTRVRELAAGRPVITTSIVQDQ 365
Query: 515 GVDNLTNLEDRLFYEIRFRREDLYYWDSVGEIATIPPPPRAVI*DLYSININIP 676
G+D L LF+E D+ Y + IA + RAV L +I +++P
Sbjct: 366 GIDELEAAIASLFFESGIESGDVTYVSNSRHIALLEQAKRAVEDALEAIEMDVP 419
>sp|O66841|NUOF_AQUAE NADH-quinone oxidoreductase chain F (NADH dehydrogenase I, chain F)
(NDH-1, chain F)
Length = 426
Score = 30.8 bits (68), Expect = 3.4
Identities = 19/60 (31%), Positives = 27/60 (45%)
Frame = +2
Query: 116 FFYLMRWERRRFMGPKSYIPIWKYGKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVG 295
F M WE R++GP Y G K F PV+G G+ + + T+ E I + G
Sbjct: 229 FIISMGWEEYRYIGPSDYA-----GPKLF--PVSGKVKKPGVYELPMNTTLREVIFKYAG 281
>sp|Q8RFJ8|SYA_FUSNN Alanyl-tRNA synthetase (Alanine--tRNA ligase) (AlaRS)
Length = 867
Score = 30.4 bits (67), Expect = 4.4
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 9/75 (12%)
Frame = +2
Query: 389 LLKLQVKIMETIKPIYP--------IVCLDKLERECFTDTLNDLPTLEDIGVDN-LTNLE 541
+ K+ K++E + YP I + K+E E F++TL+ L + +DN LTN +
Sbjct: 322 MYKMVDKVVEKFEIAYPDLRKNVENIRKIVKIEEEKFSNTLDQGIQLVNQEIDNLLTNGK 381
Query: 542 DRLFYEIRFRREDLY 586
++L EI F+ D Y
Sbjct: 382 NKLDGEISFKLYDTY 396
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,159,093
Number of Sequences: 369166
Number of extensions: 1748815
Number of successful extensions: 4766
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4648
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4760
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5733423530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)