Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_M24
(529 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q16795|NUEM_HUMAN NADH-ubiquinone oxidoreductase 39 kDa ... 94 3e-19
sp|P34943|NUEM_BOVIN NADH-ubiquinone oxidoreductase 39 kDa ... 91 1e-18
sp|Q9DC69|NUEM_MOUSE NADH-ubiquinone oxidoreductase 39 kDa ... 90 3e-18
sp|P25284|NUEM_NEUCR NADH-ubiquinone oxidoreductase 40 kDa ... 36 0.066
sp|P03922|NU5M_XENLA NADH-ubiquinone oxidoreductase chain 5... 32 0.95
sp|P27169|PON1_HUMAN Serum paraoxonase/arylesterase 1 (PON ... 31 1.6
sp|O66841|NUOF_AQUAE NADH-quinone oxidoreductase chain F (N... 31 2.1
sp|Q91090|PON2_MELGA Serum paraoxonase/arylesterase 2 (PON ... 30 3.6
sp|Q90952|PON2_CHICK Serum paraoxonase/arylesterase 2 (PON ... 30 3.6
sp|P54855|UDB15_HUMAN UDP-glucuronosyltransferase 2B15 prec... 30 4.7
>sp|Q16795|NUEM_HUMAN NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial
precursor (Complex I-39KD) (CI-39KD)
Length = 377
Score = 93.6 bits (231), Expect = 3e-19
Identities = 64/167 (38%), Positives = 86/167 (51%), Gaps = 2/167 (1%)
Frame = +3
Query: 3 KGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKYGKKTFK 182
K +GE V FPEA+I +P+D++G D F R GP IP+ G KT K
Sbjct: 184 KAVGEKVVRDAFPEAIIVKPSDIFGREDRFLNSFASMHR---FGP---IPLGSLGWKTVK 237
Query: 183 QPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLRFKPEKLVISNMD 362
QPV DV+KGI+N V DP + VGP RY L HL+ +++ V +L +
Sbjct: 238 QPVYVVDVSKGIVNAVKDPDANGKSFAFVGPSRYLLFHLVKYIFAV----AHRLFLPFPL 293
Query: 363 PLLKLQ-VKIMETIKPIYPIVCLDKLERECFTD-TLNDLPTLEDIGV 497
PL + V + I P P + DK+ER TD L LP LED+G+
Sbjct: 294 PLFAYRWVARVFEISPFEPWITRDKVERMHITDMKLPHLPGLEDLGI 340
>sp|P34943|NUEM_BOVIN NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial
precursor (Complex I-39KD) (CI-39KD)
Length = 380
Score = 91.3 bits (225), Expect = 1e-18
Identities = 66/171 (38%), Positives = 84/171 (49%), Gaps = 5/171 (2%)
Frame = +3
Query: 3 KGIGELEVLREFPEAVIFRPADMYGHNDHFFFYL--MRWERRRFMGPKSYIPIWKYGKKT 176
K +GE EV FPEA I +PA+++G D F Y +RW F G +P+ GKKT
Sbjct: 184 KAVGEKEVRETFPEATIIKPAEIFGREDRFLNYFANIRW----FGG----VPLISLGKKT 235
Query: 177 FKQPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLR--FKPEKLVI 350
KQPV DV KGIIN + DP VGP RY L L+ +++ V F P L
Sbjct: 236 VKQPVYIVDVTKGIINAIKDPDARGKTFAFVGPSRYLLFDLVQYVFAVAHRPFLPYPL-- 293
Query: 351 SNMDPLLKLQVKIMETIKPIYPIVCLDKLERECFTD-TLNDLPTLEDIGVD 500
+ + I P P DK+ER TD L LP LED+GV+
Sbjct: 294 ---PHFAYRWIGRLFEISPFEPWTTRDKVERIHTTDKILPHLPGLEDLGVE 341
>sp|Q9DC69|NUEM_MOUSE NADH-ubiquinone oxidoreductase 39 kDa subunit, mitochondrial
precursor (Complex I-39KD) (CI-39KD)
Length = 377
Score = 90.1 bits (222), Expect = 3e-18
Identities = 61/168 (36%), Positives = 86/168 (51%), Gaps = 3/168 (1%)
Frame = +3
Query: 3 KGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKYGKKTFK 182
K +GE EV FPEA+I RP+D++G D F + + R F+ +P+ G KT K
Sbjct: 184 KAVGEKEVRSVFPEAIIIRPSDIFGREDRFLNHFANY--RWFLA----VPLVSLGFKTVK 237
Query: 183 QPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLR--FKPEKLVISN 356
QPV DV+KGI+N DP GP+RY L HL+ +++ + F P L +
Sbjct: 238 QPVYVADVSKGIVNATKDPDAVGKTFAFTGPNRYLLFHLVKYIFGMTHRTFIPYPLPLFV 297
Query: 357 MDPLLKLQVKIMETIKPIYPIVCLDKLERECFTDTL-NDLPTLEDIGV 497
+ KL + P P DK+ER +D + DLP LED+GV
Sbjct: 298 YSWIGKL-----FGLSPFEPWTTKDKVERIHISDVMPTDLPGLEDLGV 340
>sp|P25284|NUEM_NEUCR NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial
precursor (Complex I-40KD) (CI-40KD)
Length = 375
Score = 35.8 bits (81), Expect = 0.066
Identities = 39/173 (22%), Positives = 68/173 (39%), Gaps = 7/173 (4%)
Frame = +3
Query: 3 KGIGELEVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKYGKKTFK 182
K GE V FPE I RPA M+G D L + + G +
Sbjct: 181 KARGEQVVRSIFPETTIVRPAPMFGFEDRLLHKLASVKN----------ILTSNGMQEKY 230
Query: 183 QPVAGYDVAKGIINVVNDPTISETIIEAVGPHRYRLDHLIWWLYMVLRFKPEKLVISNMD 362
PV DV + + ++ D + E GP Y + + + +K + V
Sbjct: 231 NPVHVIDVGQALEQMLWDDNTASETFELYGPKTYTTAEISEMVDREI-YKRRRHV----- 284
Query: 363 PLLKLQVKIMETIKPI------YPIVCLDKLERECFTDTLN-DLPTLEDIGVD 500
+ KI++ I + +PI+ D++ERE ++ + T +D+G++
Sbjct: 285 ---NVPKKILKPIAGVLNKALWWPIMSADEIEREFHDQVIDPEAKTFKDLGIE 334
>sp|P03922|NU5M_XENLA NADH-ubiquinone oxidoreductase chain 5 (NADH dehydrogenase subunit
5)
Length = 604
Score = 32.0 bits (71), Expect = 0.95
Identities = 34/113 (30%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
Frame = -1
Query: 520 SSKFVKLSTPISSKVGKSFNVSVK--HSLSNLSKQTIG*MGLIVSIIFTCNLRRGSMLLI 347
SS + +S I + +FN+++ H L S +T + +I IIF L +G +
Sbjct: 9 SSMLITISILILPILMSTFNMNIMNLHHLIKTSVKTAFLISIIPLIIF---LDQGLESIT 65
Query: 346 TNFSGLNLNTIYSHQIR*SKRYRCGPTASIIVSLIVGSLTTLIIPFATSYPAT 188
TNF +N+NT I S ++ + I ++L V T I+ FAT Y A+
Sbjct: 66 TNFHWMNINTF---DINMSFKFDIYSSIFIPIALFV---TWSILEFATWYMAS 112
>sp|P27169|PON1_HUMAN Serum paraoxonase/arylesterase 1 (PON 1) (Serum
aryldialkylphosphatase 1) (A-esterase 1) (Aromatic
esterase 1) (K-45)
Length = 355
Score = 31.2 bits (69), Expect = 1.6
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Frame = +3
Query: 21 EVLREFPEAVIFRPADMYGHNDHFFF--YLMRWERRRFMGPKSYIPIWKYGKKTFKQPVA 194
++L + V P YG NDH+F YL WE ++G ++ + Y +
Sbjct: 162 KLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWE--MYLG-LAWSYVVYYSPSEVRVVAE 218
Query: 195 GYDVAKGI 218
G+D A GI
Sbjct: 219 GFDFANGI 226
>sp|O66841|NUOF_AQUAE NADH-quinone oxidoreductase chain F (NADH dehydrogenase I, chain F)
(NDH-1, chain F)
Length = 426
Score = 30.8 bits (68), Expect = 2.1
Identities = 19/60 (31%), Positives = 27/60 (45%)
Frame = +3
Query: 93 FFYLMRWERRRFMGPKSYIPIWKYGKKTFKQPVAGYDVAKGIINVVNDPTISETIIEAVG 272
F M WE R++GP Y G K F PV+G G+ + + T+ E I + G
Sbjct: 229 FIISMGWEEYRYIGPSDYA-----GPKLF--PVSGKVKKPGVYELPMNTTLREVIFKYAG 281
>sp|Q91090|PON2_MELGA Serum paraoxonase/arylesterase 2 (PON 2) (Serum
aryldialkylphosphatase 2) (A-esterase 2) (Aromatic
esterase 2)
Length = 354
Score = 30.0 bits (66), Expect = 3.6
Identities = 17/66 (25%), Positives = 30/66 (45%)
Frame = +3
Query: 21 EVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKYGKKTFKQPVAGY 200
++L + V P Y NDH+F+ + ++G ++ + Y K K+ AG+
Sbjct: 161 DLLTSVNDVVAVGPDSFYATNDHYFYDFILMFLEMYLG-LTWSNVVYYSPKEVKEVAAGF 219
Query: 201 DVAKGI 218
A GI
Sbjct: 220 YSANGI 225
>sp|Q90952|PON2_CHICK Serum paraoxonase/arylesterase 2 (PON 2) (Serum
aryldialkylphosphatase 2) (A-esterase 2) (Aromatic
esterase 2)
Length = 354
Score = 30.0 bits (66), Expect = 3.6
Identities = 17/66 (25%), Positives = 30/66 (45%)
Frame = +3
Query: 21 EVLREFPEAVIFRPADMYGHNDHFFFYLMRWERRRFMGPKSYIPIWKYGKKTFKQPVAGY 200
++L + V P Y NDH+F+ + ++G ++ + Y K K+ AG+
Sbjct: 161 DLLTSVNDVVAVGPDSFYATNDHYFYDFILMFLEMYLG-LTWSNVVYYSPKEVKEVAAGF 219
Query: 201 DVAKGI 218
A GI
Sbjct: 220 YSANGI 225
>sp|P54855|UDB15_HUMAN UDP-glucuronosyltransferase 2B15 precursor (UDPGT) (UDPGTh-3)
(HLUG4)
Length = 530
Score = 29.6 bits (65), Expect = 4.7
Identities = 14/51 (27%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Frame = +3
Query: 201 DVAKGIINVVNDPTISETIIEAVGPHRYR----LDHLIWWLYMVLRFKPEK 341
D+ + +V+NDP E +++ H + LD ++W+ V+R K K
Sbjct: 425 DLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAK 475
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,710,699
Number of Sequences: 369166
Number of extensions: 1331213
Number of successful extensions: 3200
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3138
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3195
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3551563800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)