Planaria EST Database

DrC_00078

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00078
         (1412 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9VKJ0|HGD_DROME  Homogentisate 1,2-dioxygenase (Homogent...   241   4e-63
sp|Q9Y041|HGD_CAEEL  Homogentisate 1,2-dioxygenase (Homogent...   223   1e-57
sp|Q93099|HGD_HUMAN  Homogentisate 1,2-dioxygenase (Homogent...   220   7e-57
sp|O09173|HGD_MOUSE  Homogentisate 1,2-dioxygenase (Homogent...   218   4e-56
sp|Q9ZRA2|HGD_ARATH  Homogentisate 1,2-dioxygenase (Homogent...   197   5e-50
sp|Q00667|HGD_EMENI  Homogentisate 1,2-dioxygenase (Homogent...   187   6e-47
sp|Q87Z79|HGD_PSESM  Homogentisate 1,2-dioxygenase (Homogent...   176   2e-43
sp|Q9S2B5|HGD_STRCO  Homogentisate 1,2-dioxygenase (Homogent...   174   7e-43
sp|Q9A5B8|HGD_CAUCR  Homogentisate 1,2-dioxygenase (Homogent...   171   5e-42
sp|Q9X4G0|HGD_PSEAE  Homogentisate 1,2-dioxygenase (Homogent...   168   4e-41

>sp|Q9VKJ0|HGD_DROME Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 439

 Score =  241 bits (615), Expect = 4e-63
 Identities = 121/178 (67%), Positives = 141/178 (79%)
 Frame = +3

Query: 3   NKAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYIL 182
           N AF+NSD DFL+VPQ+G L + TEFG+  VAP EI VI QGI+++VN+ DS S  GYIL
Sbjct: 145 NSAFYNSDGDFLIVPQQGVLDITTEFGRMSVAPNEICVIPQGIRFAVNV-DSPS-RGYIL 202

Query: 183 EVCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQE 362
           EV  +HFVLP+LGPIGANGLAN RDF T VAWFD+  +K    F +I+K+QG LF A Q 
Sbjct: 203 EVYDDHFVLPDLGPIGANGLANPRDFETPVAWFDDRDVK---DFQVISKFQGRLFVAKQN 259

Query: 363 HTCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVI 536
           HT FDVV W GNY P+KYDL+ FMVINSVSFDH DPSIFTVLTCPSL+ GTA+ADFVI
Sbjct: 260 HTVFDVVAWHGNYVPFKYDLSKFMVINSVSFDHCDPSIFTVLTCPSLRAGTAIADFVI 317

>sp|Q9Y041|HGD_CAEEL Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 437

 Score =  223 bits (567), Expect = 1e-57
 Identities = 113/176 (64%), Positives = 133/176 (75%)
 Frame = +3

Query: 9   AFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYILEV 188
           A +NSD DFL+VPQ+GAL + TEFG+ +V P EI VI QGI++SV +     + GYILEV
Sbjct: 149 AMYNSDGDFLIVPQQGALEITTEFGRLLVNPQEIAVIPQGIRFSVAVRGP--SRGYILEV 206

Query: 189 CGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQEHT 368
            G HF LP+LGPIGANGLAN RDF   VAWF++  +    +FT+INKYQG  F A Q H+
Sbjct: 207 YGTHFQLPDLGPIGANGLANPRDFEAPVAWFEDLDV----EFTIINKYQGSWFQAKQGHS 262

Query: 369 CFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVI 536
            FDVV W GNY PYKYDL  FMVIN+VSFDH DPSIFTVLT PS+K GTA+ADFVI
Sbjct: 263 PFDVVGWHGNYVPYKYDLKKFMVINTVSFDHCDPSIFTVLTAPSVKHGTAIADFVI 318

>sp|Q93099|HGD_HUMAN Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 445

 Score =  220 bits (561), Expect = 7e-57
 Identities = 106/178 (59%), Positives = 138/178 (77%)
 Frame = +3

Query: 3   NKAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYIL 182
           N+ F+NSD DFL+VPQ+G L + TEFGK +V P EI VIQ+G+++S+++ +     GYIL
Sbjct: 144 NRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEICVIQRGMRFSIDVFEE--TRGYIL 201

Query: 183 EVCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQE 362
           EV G HF LP+LGPIGANGLAN RDFL  +AW+++  +     +T+INKYQG+LF A Q+
Sbjct: 202 EVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVPGG--YTVINKYQGKLFAAKQD 259

Query: 363 HTCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVI 536
            + F+VV W GNY PYKY+L +FMVINSV+FDH DPSIFTVLT  S++PG A+ADFVI
Sbjct: 260 VSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGVAIADFVI 317

>sp|O09173|HGD_MOUSE Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 445

 Score =  218 bits (554), Expect = 4e-56
 Identities = 106/178 (59%), Positives = 137/178 (76%)
 Frame = +3

Query: 3   NKAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYIL 182
           N+ F+NSD DFL+VPQ+G L + TEFGK  + P EI VIQ+G+++SV++ +     GYIL
Sbjct: 144 NRCFYNSDGDFLIVPQKGKLLIYTEFGKMSLQPNEICVIQRGMRFSVDVFEE--TRGYIL 201

Query: 183 EVCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQE 362
           EV G HF LP+LGPIGANGLAN RDFL  VAW+++  +     +T+INK+QG+LF   Q+
Sbjct: 202 EVYGVHFELPDLGPIGANGLANPRDFLIPVAWYEDRRVPGG--YTVINKFQGKLFACKQD 259

Query: 363 HTCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVI 536
            + F+VVTW GNY PYKY+L +FMVIN+V+FDH DPSIFTVLT  SL+PG A+ADFVI
Sbjct: 260 VSPFNVVTWHGNYTPYKYNLENFMVINAVAFDHADPSIFTVLTAKSLRPGVAIADFVI 317

>sp|Q9ZRA2|HGD_ARATH Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 461

 Score =  197 bits (502), Expect = 5e-50
 Identities = 102/178 (57%), Positives = 126/178 (70%)
 Frame = +3

Query: 3   NKAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYIL 182
           + AF N+D DFLLVPQ G L + TE G+ +V PGEI VI QG ++S++L D KS  GY+ 
Sbjct: 150 DSAFCNADGDFLLVPQTGRLWIETECGRLLVTPGEIAVIPQGFRFSIDLPDGKS-RGYVA 208

Query: 183 EVCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQE 362
           E+ G HF LP+LGPIGANGLA SRDFL   AWF ED ++   ++T++ K+ GELF A Q+
Sbjct: 209 EIYGAHFQLPDLGPIGANGLAASRDFLAPTAWF-EDGLRP--EYTIVQKFGGELFTAKQD 265

Query: 363 HTCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVI 536
            + F+VV W GNY PYKYDL  F   N+V  DH DPSI TVLT P+ KPG AL DFVI
Sbjct: 266 FSPFNVVAWHGNYVPYKYDLKKFCPYNTVLLDHGDPSINTVLTAPTDKPGVALLDFVI 323

>sp|Q00667|HGD_EMENI Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 448

 Score =  187 bits (475), Expect = 6e-47
 Identities = 95/177 (53%), Positives = 121/177 (68%)
 Frame = +3

Query: 6   KAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYILE 185
           +AF+++D DFL+V Q G L + TE G+ +V P EI VI +G++Y V L D     GYI E
Sbjct: 149 EAFYSADGDFLIVAQHGVLDIQTELGRLLVRPNEICVIPRGVRYRVTLPDGP-VRGYICE 207

Query: 186 VCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQEH 365
           +   H+ LP LGPIG+NGLAN+RDF   VA FD++   T  ++ L +K+   LF A Q+H
Sbjct: 208 LYQGHYQLPELGPIGSNGLANARDFQAPVAAFDDEEGPT--EYRLYSKFNNHLFSARQDH 265

Query: 366 TCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVI 536
           T FD+V W GNY PYKYDL  F  + SVSFDH DPSI+TVLT PS   GTA+ADFVI
Sbjct: 266 TPFDIVAWHGNYYPYKYDLGRFNTMGSVSFDHPDPSIYTVLTGPSDHVGTAIADFVI 322

>sp|Q87Z79|HGD_PSESM Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 434

 Score =  176 bits (445), Expect = 2e-43
 Identities = 92/177 (51%), Positives = 117/177 (66%)
 Frame = +3

Query: 6   KAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYILE 185
           +AFF++D ++L+VPQ+G L ++TE G   + P EI V+ +G+K+SV LLD  SA GY+ E
Sbjct: 143 RAFFSADGEWLIVPQQGRLRIITEMGVLDIGPLEIAVLPRGLKFSVQLLDG-SARGYLCE 201

Query: 186 VCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQEH 365
             G    LP LGPIG+NGLAN RDFLT VAWF+E     +    L+ K+ GEL+    +H
Sbjct: 202 NHGGVLRLPELGPIGSNGLANPRDFLTPVAWFEE----RDEPVQLVQKFLGELWTTQLQH 257

Query: 366 TCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVI 536
           + FDVV W GN  PY YDL  F  I +VS+DH DPSIFTVLT P    G A  DFVI
Sbjct: 258 SPFDVVGWHGNNVPYTYDLRRFNTIGTVSYDHPDPSIFTVLTSPGAVHGQANIDFVI 314

>sp|Q9S2B5|HGD_STRCO Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 441

 Score =  174 bits (440), Expect = 7e-43
 Identities = 90/189 (47%), Positives = 123/189 (65%)
 Frame = +3

Query: 3   NKAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYIL 182
           ++ F ++D + L+VP+ G L + TEFG     PG + +I +G+++ V LLD + A GY+ 
Sbjct: 147 DRVFSDADGELLIVPERGGLLLRTEFGLLHAEPGHVALIPRGVRFRVQLLD-EDARGYVC 205

Query: 183 EVCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQE 362
           E  G  F LP+LGPIGANGLAN+RDF   VA +++D   T     ++NK+ G L+ A  +
Sbjct: 206 ENYGAPFQLPDLGPIGANGLANARDFRAPVAAYEDDE-STPGPVEVVNKFCGNLWTAEYD 264

Query: 363 HTCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVISS 542
           H+  DVV W GN+ PY YDL  F VI S+S+DH DPSIFTVLT PS  PG A  DFV+ +
Sbjct: 265 HSPLDVVAWHGNHVPYVYDLRRFNVIGSISYDHPDPSIFTVLTSPSDTPGLAGVDFVVFA 324

Query: 543 CRIIGGGDT 569
            R + G DT
Sbjct: 325 PRWLVGEDT 333

>sp|Q9A5B8|HGD_CAUCR Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 425

 Score =  171 bits (433), Expect = 5e-42
 Identities = 95/189 (50%), Positives = 121/189 (64%)
 Frame = +3

Query: 3   NKAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYIL 182
           N+ F+N+D + L+VPQ G L+++TE G     PG I VI +G+++ V +     A GY+ 
Sbjct: 137 NRVFYNADGEMLIVPQMGELTLVTEMGVLKAGPGHIAVIPRGVRFRVEV--EGPARGYVC 194

Query: 183 EVCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQE 362
           E  G  F LP LGPIGANGLAN RDF   VA F++  I T  Q  +I K+QG L+ A  +
Sbjct: 195 ENYGAAFRLPELGPIGANGLANPRDFEAPVAAFED--IDTPTQ--VIQKFQGALWAATWD 250

Query: 363 HTCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVISS 542
           H+  DVV W GN  PY+YDL+ F  IN+VS+DH DPSIFTVLT PS  PGTA  DFVI  
Sbjct: 251 HSPLDVVAWHGNLTPYRYDLSRFNTINTVSYDHPDPSIFTVLTSPSDTPGTANCDFVIFP 310

Query: 543 CRIIGGGDT 569
            R +   DT
Sbjct: 311 PRWMVAEDT 319

>sp|Q9X4G0|HGD_PSEAE Homogentisate 1,2-dioxygenase (Homogentisicase) (Homogentisate
           oxygenase) (Homogentisic acid oxidase)
          Length = 432

 Score =  168 bits (425), Expect = 4e-41
 Identities = 92/177 (51%), Positives = 114/177 (64%)
 Frame = +3

Query: 6   KAFFNSDWDFLLVPQEGALSVLTEFGKFIVAPGEIIVIQQGIKYSVNLLDSKSANGYILE 185
           + F+++D + LLVPQ G L + TE G   V P EI VI +G+K+ V LLD + A GYI E
Sbjct: 141 RCFYDADGELLLVPQLGRLRLCTELGALQVEPLEIAVIPRGMKFRVELLDGE-ARGYIAE 199

Query: 186 VCGNHFVLPNLGPIGANGLANSRDFLTCVAWFDEDAIKTNNQFTLINKYQGELFYAHQEH 365
             G    LP+LGPIG+NGLAN RDFLT VA +++    +     L+ KY GEL+    +H
Sbjct: 200 NHGAPLRLPDLGPIGSNGLANPRDFLTPVARYED----SRQPLQLVQKYLGELWACELDH 255

Query: 366 TCFDVVTWSGNYAPYKYDLASFMVINSVSFDHVDPSIFTVLTCPSLKPGTALADFVI 536
           +  DVV W GN  PYKYDL  F  I +VSFDH DPSIFTVLT P+  PG A  DFVI
Sbjct: 256 SPLDVVAWHGNNVPYKYDLRRFNTIGTVSFDHPDPSIFTVLTSPTSVPGLANIDFVI 312

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 161,712,664
Number of Sequences: 369166
Number of extensions: 3450029
Number of successful extensions: 9471
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8798
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9419
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 16837087640
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00078

  1. Dr_sW_003_A02
  2. Dr_sW_011_F20
  3. Dr_sW_002_N13