Planaria EST Database

DrC_00059

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00059
         (1035 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q13530|SERC3_HUMAN  Serine incorporator 3 (Tumor differen...   271   3e-72
sp|Q9QZI9|SERC3_MOUSE  Serine incorporator 3 (Tumor differen...   270   6e-72
sp|Q9NRX5|SERC1_HUMAN  Serine incorporator 1 (Tumor differen...   267   3e-71
sp|Q9QZI8|SERC1_MOUSE  Serine incorporator 1 (Tumor differen...   262   1e-69
sp|Q8K0E7|SERC2_MOUSE  Serine incorporator 2 (Tumor differen...   235   1e-61
sp|Q96SA4|SERC2_HUMAN  Serine incorporator 2 (Tumor differen...   231   3e-60
sp|Q9HDY3|YK17_SCHPO  Membrane protein PB1A10.07c                 138   3e-32
sp|Q12116|TMS1_YEAST  Membrane protein TMS1                       129   1e-29
sp|Q41706|UPSA3_VIGUN  Probable ureide permease A3 (VuA3)          35   0.27 
sp|P16415|ZF36_HUMAN  Zinc finger protein ZFP-36                   32   3.9  

>sp|Q13530|SERC3_HUMAN Serine incorporator 3 (Tumor differentially expressed protein 1)
          Length = 473

 Score =  271 bits (692), Expect = 3e-72
 Identities = 135/303 (44%), Positives = 190/303 (62%), Gaps = 7/303 (2%)
 Frame = +2

Query: 2    FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
            FILIQL+LLVDFAHSWNESW++  EE + + +Y  L+ FT  F                 
Sbjct: 171  FILIQLVLLVDFAHSWNESWVNRMEEGNPRLWYAALLSFTSAFYILSIICVGLLYTYYTK 230

Query: 182  YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
               C  NKFFIS N+ILCV+ S ISI P+I EH PRSGLLQSS++TLYT+YLTWSAM+N 
Sbjct: 231  PDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNE 290

Query: 362  SDKNCNPSLIVY-------TYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIY 520
             D++CNP+L+ +       T     +T +  T +P + S         +GL +F++ ++Y
Sbjct: 291  PDRSCNPNLMSFITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLY 350

Query: 521  SSIRSSGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNEEDGVAYDYSFFHF 700
            SSIR+S ++ V KLT+ GS++ IL D  +     +     +   DNE++GV Y YS FH 
Sbjct: 351  SSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHL 410

Query: 701  MFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYLWTLMAPCLFPDR 880
            M  L SLY+MMTLT+WY P +   ++ +   +VWVKI SSW+C+ +Y+WTL+AP +   R
Sbjct: 411  MLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSWVCLLLYVWTLVAPLVLTSR 470

Query: 881  EFN 889
            +F+
Sbjct: 471  DFS 473

>sp|Q9QZI9|SERC3_MOUSE Serine incorporator 3 (Tumor differentially expressed protein 1)
            (Membrane protein TMS-1) (Axotomy-induced glycoprotein 1)
            (Axotomy-induced glyco/Golgi protein 1) (AIGP-1)
          Length = 472

 Score =  270 bits (689), Expect = 6e-72
 Identities = 137/305 (44%), Positives = 194/305 (63%), Gaps = 9/305 (2%)
 Frame = +2

Query: 2    FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
            FI+IQL+LLVD AHSWNE W++  EE + + +Y  L+ FT  F                 
Sbjct: 171  FIIIQLVLLVDMAHSWNELWVNRMEEGNPRLWYAALLSFTSLFYILSIVFAALLYVFYTK 230

Query: 182  YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
              +C  NK FIS N+I CV +S +SILP++ EH PRSGLLQSS++TLYT+YLTWSAMTN 
Sbjct: 231  PDDCTENKVFISLNLIFCVAVSIVSILPKVQEHQPRSGLLQSSIITLYTLYLTWSAMTNE 290

Query: 362  SDKNCNPSLI-VYTYNTSKT------TGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIY 520
             +++CNPSL+ + T+ TS T      T +    +P + S    +   I GL+IF+  +IY
Sbjct: 291  PERSCNPSLMSIITHLTSPTVSPANSTTLAPAYAPPSQSGHFMNLDDIWGLIIFVFCLIY 350

Query: 521  SSIRSSGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQ--SVWDNEEDGVAYDYSFF 694
            SS R+S ++ V KLT+ GS++ IL D  +G   + ++E GQ     DNE++GV Y YSFF
Sbjct: 351  SSFRTSSNSQVNKLTLSGSDSVILGDTTNG---ANDEEDGQPRRAVDNEKEGVQYSYSFF 407

Query: 695  HFMFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYLWTLMAPCLFP 874
            H M    SLY+MMT+T+WY P +    +++   +VW K+ SSWLC+ +YLWTL+AP +  
Sbjct: 408  HLMLCCASLYIMMTITSWYSPDAKFQKVSSKWLAVWFKMGSSWLCLLLYLWTLVAPLVLT 467

Query: 875  DREFN 889
             R+F+
Sbjct: 468  GRDFS 472

>sp|Q9NRX5|SERC1_HUMAN Serine incorporator 1 (Tumor differentially expressed protein 2)
            (Tumor differentially expressed 1 protein-like)
          Length = 453

 Score =  267 bits (683), Expect = 3e-71
 Identities = 143/302 (47%), Positives = 191/302 (63%), Gaps = 6/302 (1%)
 Frame = +2

Query: 2    FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
            FILIQL+LL+DFAHSWNESW++  EE +++ +Y  L+  T                    
Sbjct: 163  FILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTH 222

Query: 182  YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
               C+ NK FIS NM+LCV  S +SILP+I E  PRSGLLQSS++T+YT+YLTWSAMTN 
Sbjct: 223  PASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNE 282

Query: 362  SDKNCNPSLI-VYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSS 538
             + NCNPSL+ +  YNT+      +T+     S Q W    I+GL++FL+ V YSSIR+S
Sbjct: 283  PETNCNPSLLSIIGYNTT------STVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTS 336

Query: 539  GHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVW---DNEEDGVAYDYSFFHFMFF 709
             ++ V KLT+   E+ ++ D   G     + E G  V    DNE DGV Y YSFFHFM F
Sbjct: 337  NNSQVNKLTLTSDESTLIED--GGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLF 394

Query: 710  LGSLYVMMTLTNW--YQPSSNLMTLNANDASVWVKIVSSWLCIAIYLWTLMAPCLFPDRE 883
            L SLY+MMTLTNW  Y+PS     + +   +VWVKI SSW+ I +Y+WTL+AP +  +R+
Sbjct: 395  LASLYIMMTLTNWYRYEPSRE---MKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRD 451

Query: 884  FN 889
            F+
Sbjct: 452  FD 453

>sp|Q9QZI8|SERC1_MOUSE Serine incorporator 1 (Tumor differentially expressed protein 2)
            (Tumor differentially expressed 1 protein-like) (Membrane
            protein TMS-2) (Axotomy-induced glyco/Golgi protein 2)
          Length = 453

 Score =  262 bits (670), Expect = 1e-69
 Identities = 140/300 (46%), Positives = 188/300 (62%), Gaps = 4/300 (1%)
 Frame = +2

Query: 2    FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
            FILIQL+LL+DFAHSWNESW++  EE +++ +Y  L+  T                    
Sbjct: 163  FILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAVVLFFVYYTH 222

Query: 182  YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
               CA NK FIS NM+LC+  S +SILP+I E  PRSGLLQSS++T+YT+YLTWSAMTN 
Sbjct: 223  PASCAENKAFISVNMLLCIGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNE 282

Query: 362  SDKNCNPSLI-VYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSS 538
             + NCNPSL+ +  +NT++       I     S Q W    I+GLV+FL+ V YSSIR+S
Sbjct: 283  PETNCNPSLLSIIGFNTTR------PIPKDGQSVQWWHPQGIIGLVLFLLCVFYSSIRTS 336

Query: 539  GHTSVGKLTMHGSETAILSDQESGVPVSKNQETG-QSVWDNEEDGVAYDYSFFHFMFFLG 715
             ++ V KLT+   E+ ++ D       S +   G     DNE DGV Y YSFFHFM FL 
Sbjct: 337  NNSQVNKLTLTSDESTLIEDGNGRSDGSLDDGDGIHRAVDNERDGVTYSYSFFHFMLFLA 396

Query: 716  SLYVMMTLTNW--YQPSSNLMTLNANDASVWVKIVSSWLCIAIYLWTLMAPCLFPDREFN 889
            SLY+MMTLTNW  Y+PS     + +   +VWVKI SSW+ + +Y+WTL+AP +  +R+F+
Sbjct: 397  SLYIMMTLTNWYRYEPSRE---MKSQWTAVWVKISSSWIGLVLYVWTLVAPLVLTNRDFD 453

>sp|Q8K0E7|SERC2_MOUSE Serine incorporator 2 (Tumor differentially expressed 2-like)
          Length = 450

 Score =  235 bits (600), Expect = 1e-61
 Identities = 131/296 (44%), Positives = 170/296 (57%)
 Frame = +2

Query: 2    FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
            FILIQLIL VDFAHSWN+ W+   EE D+ A+Y GL FFT  F                 
Sbjct: 170  FILIQLILFVDFAHSWNQRWLCKAEECDSPAWYAGLFFFTFLFYLLSIAAVALMFVYYTE 229

Query: 182  YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
               C   K FIS N+  CV +S I++LP++ +  P SGLLQ+S++TLYT+++TWSA++N 
Sbjct: 230  SGACHEGKVFISLNLTFCVCVSIIAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSNV 289

Query: 362  SDKNCNPSLIVYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSSG 541
             D+ CNP L      T   TG    +     S   W    IVGLVIF++   + S+RSS 
Sbjct: 290  PDQKCNPHL-----PTKNGTGQ---VDLEDYSTVWWDAPSIVGLVIFILCTFFISLRSSD 341

Query: 542  HTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNEEDGVAYDYSFFHFMFFLGSL 721
            H  V  L M   E      Q+  V VS  +      +DNE+DGV Y YSFFHF   L SL
Sbjct: 342  HRQVNSL-MQTEECPAEMVQQQQVAVSDGR-----AYDNEQDGVTYSYSFFHFCLVLASL 395

Query: 722  YVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYLWTLMAPCLFPDREFN 889
            +VMMTLTNWY P      + +   SVWVKI +SW  + +YLWTL+AP L P+R+F+
Sbjct: 396  HVMMTLTNWYSPGETRKMI-STWTSVWVKICASWAGLFLYLWTLVAPLLLPNRDFS 450

>sp|Q96SA4|SERC2_HUMAN Serine incorporator 2 (Tumor differentially expressed 2-like)
          Length = 456

 Score =  231 bits (589), Expect = 3e-60
 Identities = 124/303 (40%), Positives = 173/303 (57%), Gaps = 7/303 (2%)
 Frame = +2

Query: 2    FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
            FILIQL+LL+DFAHSWN+ W+   EE D++A+Y GL FFT+ F                 
Sbjct: 170  FILIQLVLLIDFAHSWNQRWLGKAEECDSRAWYAGLFFFTLLFYLLSIAAVALMFMYYTE 229

Query: 182  YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
               C   K FIS N+  CV +S  ++LP++ +  P SGLLQ+S++TLYT+++TWSA+++ 
Sbjct: 230  PSGCHEGKVFISLNLTFCVCVSIAAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSSI 289

Query: 362  SDKNCNPSLIVYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSSG 541
             ++ CNP L     N +   G      P     Q W    IVGL+IFL+  ++ S+RSS 
Sbjct: 290  PEQKCNPHLPTQLGNETVVAG------PEGYETQWWDAPSIVGLIIFLLCTLFISLRSSD 343

Query: 542  HTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSV-------WDNEEDGVAYDYSFFHF 700
            H  V  L         +  +E    +   Q+  Q V       +DNE+DGV Y YSFFHF
Sbjct: 344  HRQVNSL---------MQTEECPPMLDATQQQQQQVAACEGRAFDNEQDGVTYSYSFFHF 394

Query: 701  MFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYLWTLMAPCLFPDR 880
               L SL+VMMTLTNWY+P      ++   A VWVKI +SW  + +YLWTL+AP L  +R
Sbjct: 395  CLVLASLHVMMTLTNWYKPGETRKMISTWTA-VWVKICASWAGLLLYLWTLVAPLLLRNR 453

Query: 881  EFN 889
            +F+
Sbjct: 454  DFS 456

>sp|Q9HDY3|YK17_SCHPO Membrane protein PB1A10.07c
          Length = 441

 Score =  138 bits (347), Expect = 3e-32
 Identities = 96/303 (31%), Positives = 146/303 (48%), Gaps = 10/303 (3%)
 Frame = +2

Query: 2   FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
           FI+  L+LLVDFAH+W E  +D    +D+ +  F LI  TV                   
Sbjct: 167 FIVYGLMLLVDFAHTWAERCVDRVLTSDSSSSKFYLIGSTVGMYVVGLVLTILTYVFFCA 226

Query: 182 YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
              C+ N+   + N++LC+ +S +S+ P I E+ PRSGL QSSM+  YT YL  SA+ N 
Sbjct: 227 -SSCSFNQAINTINLLLCIAVSCLSVHPTIQEYNPRSGLAQSSMVMCYTCYLILSALANR 285

Query: 362 SDK-NCNPSLIVYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSS 538
            D+  CNP               G + S          ++ ++G      T++YS++R++
Sbjct: 286 PDEGQCNP--------------WGNSASGTR------EFSKVIGAAFTFFTILYSAVRAA 325

Query: 539 GHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNEEDGVAYDYSF--FHFMFFL 712
                       S + + +D    + VS   E G S    EED    DY+F  FH +F L
Sbjct: 326 SSRE-----SDDSYSYLYADSHD-MGVSTPLEDGSS----EEDKHQSDYNFIWFHIVFVL 375

Query: 713 GSLYVMMTLTNW-----YQPSSN--LMTLNANDASVWVKIVSSWLCIAIYLWTLMAPCLF 871
            + Y    LTNW     Y+   N   + +  + A+VWVKI++SW+C  +Y+W+ +AP  F
Sbjct: 376 AAFYTASLLTNWNTTSVYENQKNDVFVRIGFSYAAVWVKIITSWVCHGLYVWSCLAPVFF 435

Query: 872 PDR 880
           P R
Sbjct: 436 PYR 438

>sp|Q12116|TMS1_YEAST Membrane protein TMS1
          Length = 473

 Score =  129 bits (324), Expect = 1e-29
 Identities = 90/330 (27%), Positives = 156/330 (47%), Gaps = 37/330 (11%)
 Frame = +2

Query: 2    FILIQLILLVDFAHSWNESWIDGYE-ENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXX 178
            FIL+ LILLVDFAH W E+ I   E E+++ +++   +                      
Sbjct: 158  FILVGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMF 217

Query: 179  GYPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTN 358
             + +C +N+  ++ N+IL V+   +S+ P+I E  P+SGL QSSM+++Y  YLT SAM++
Sbjct: 218  CHQQCNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMSS 277

Query: 359  -GSDKNCNPSLIVYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRS 535
               DK CNP  +V +  T K                   +++I+G +   I + Y++ R+
Sbjct: 278  EPDDKMCNP--LVRSSGTRK-------------------FSIILGSLFTFIAIAYTTTRA 316

Query: 536  SGHTSVGKLTMHGS----------------------ETAILSDQESGVPVSKNQETG--- 640
            + +++      +G+                      E    + +E  +P S   +T    
Sbjct: 317  AANSAFQGTNTNGAIYLGNDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLG 376

Query: 641  ----QSVWDNEED----GVAYDYSFFHFMFFLGS--LYVMMTLTNWYQPSSNLMTLNAND 790
                    DN+ D    G  Y+Y+ FH +FFL +  + +++T+        + + +    
Sbjct: 377  TSSPTGAMDNQNDDERTGTKYNYTLFHVIFFLATQWIAILLTINVTQDDVGDFIPVGRTY 436

Query: 791  ASVWVKIVSSWLCIAIYLWTLMAPCLFPDR 880
               WVKIVS+W+C A+Y WT++AP + PDR
Sbjct: 437  FYSWVKIVSAWICYALYGWTVVAPAIMPDR 466

>sp|Q41706|UPSA3_VIGUN Probable ureide permease A3 (VuA3)
          Length = 376

 Score = 35.4 bits (80), Expect = 0.27
 Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
 Frame = +2

Query: 410 SKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIR---SSGHTSVGKLTMHGSE 580
           S T  +GTT++   + + N +  L  G+  FLI V     R   S+   +  KL+ + S+
Sbjct: 119 SITVVIGTTLNYFLDDKINKAEILFPGVGCFLIAVFLGFCRFNSSNASDNKAKLSNYTSD 178

Query: 581 --TAILSDQESGVPVSKNQETGQSVWDNEEDGVA 676
                +S +ES +  SK+ E G S  DN E G A
Sbjct: 179 YKEVAISSKESDLVKSKDLERGSSSADNVEAGTA 212

>sp|P16415|ZF36_HUMAN Zinc finger protein ZFP-36
          Length = 582

 Score = 31.6 bits (70), Expect = 3.9
 Identities = 18/48 (37%), Positives = 24/48 (50%)
 Frame = -1

Query: 621 DTGTPDSWSLNIAVSEPCIVNFPTLVWPLLRILE*ITVIRNITSPTIR 478
           DT TP SW ++    E   VNF    W LL   +  ++ RN+   TIR
Sbjct: 26  DTRTPGSWEMDSVAFEDVAVNFTQEEWALLGPSQ-KSLYRNVMQETIR 72

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 120,357,937
Number of Sequences: 369166
Number of extensions: 2460750
Number of successful extensions: 5934
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5658
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5902
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 11148909035
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00059

  1. Dr_sW_002_F10
  2. Dr_sW_027_E05
  3. Dr_sW_009_B12