Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_E05
(571 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9QZI9|SERC3_MOUSE Serine incorporator 3 (Tumor differen... 133 4e-31
sp|Q13530|SERC3_HUMAN Serine incorporator 3 (Tumor differen... 132 6e-31
sp|Q9NRX5|SERC1_HUMAN Serine incorporator 1 (Tumor differen... 132 8e-31
sp|Q9QZI8|SERC1_MOUSE Serine incorporator 1 (Tumor differen... 130 3e-30
sp|Q8K0E7|SERC2_MOUSE Serine incorporator 2 (Tumor differen... 120 2e-27
sp|Q96SA4|SERC2_HUMAN Serine incorporator 2 (Tumor differen... 114 2e-25
sp|Q9HDY3|YK17_SCHPO Membrane protein PB1A10.07c 72 1e-12
sp|Q12116|TMS1_YEAST Membrane protein TMS1 66 7e-11
sp|P16415|ZF36_HUMAN Zinc finger protein ZFP-36 32 1.5
sp|P65374|MMLB_MYCTU Putative membrane protein mmpL11 >gi|5... 31 2.5
>sp|Q9QZI9|SERC3_MOUSE Serine incorporator 3 (Tumor differentially expressed protein 1)
(Membrane protein TMS-1) (Axotomy-induced glycoprotein
1) (Axotomy-induced glyco/Golgi protein 1) (AIGP-1)
Length = 472
Score = 133 bits (334), Expect = 4e-31
Identities = 61/135 (45%), Positives = 91/135 (67%)
Frame = +3
Query: 18 IVGLVIFLITVIYSSIRSRGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNE 197
I GL+IF+ +IYSS R+ ++ V KLT+ GS++ IL D +G ++ + ++V DNE
Sbjct: 338 IWGLIIFVFCLIYSSFRTSSNSQVNKLTLSGSDSVILGDTTNGANDEEDGQPRRAV-DNE 396
Query: 198 EDGVAYDYSFFHFMFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIY 377
++GV Y YSFFH M SLY+MMT+T+WY P + +++ +VW K+ SSWLC+ +Y
Sbjct: 397 KEGVQYSYSFFHLMLCCASLYIMMTITSWYSPDAKFQKVSSKWLAVWFKMGSSWLCLLLY 456
Query: 378 LWTLMAPCLFPDRDF 422
LWTL+AP + RDF
Sbjct: 457 LWTLVAPLVLTGRDF 471
>sp|Q13530|SERC3_HUMAN Serine incorporator 3 (Tumor differentially expressed protein 1)
Length = 473
Score = 132 bits (332), Expect = 6e-31
Identities = 58/134 (43%), Positives = 88/134 (65%)
Frame = +3
Query: 21 VGLVIFLITVIYSSIRSRGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNEE 200
+GL +F++ ++YSSIR+ ++ V KLT+ GS++ IL D + + + DNE+
Sbjct: 339 IGLFVFVLCLLYSSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEK 398
Query: 201 DGVAYDYSFFHFMFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYL 380
+GV Y YS FH M L SLY+MMTLT+WY P + ++ + +VWVKI SSW+C+ +Y+
Sbjct: 399 EGVQYSYSLFHLMLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSWVCLLLYV 458
Query: 381 WTLMAPCLFPDRDF 422
WTL+AP + RDF
Sbjct: 459 WTLVAPLVLTSRDF 472
>sp|Q9NRX5|SERC1_HUMAN Serine incorporator 1 (Tumor differentially expressed protein 2)
(Tumor differentially expressed 1 protein-like)
Length = 453
Score = 132 bits (331), Expect = 8e-31
Identities = 68/140 (48%), Positives = 91/140 (65%), Gaps = 5/140 (3%)
Frame = +3
Query: 18 IVGLVIFLITVIYSSIRSRGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVW--- 188
I+GL++FL+ V YSSIR+ ++ V KLT+ E+ ++ D G + E G V
Sbjct: 318 IIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIED--GGARSDGSLEDGDDVHRAV 375
Query: 189 DNEEDGVAYDYSFFHFMFFLGSLYVMMTLTNW--YQPSSNLMTLNANDASVWVKIVSSWL 362
DNE DGV Y YSFFHFM FL SLY+MMTLTNW Y+PS + + +VWVKI SSW+
Sbjct: 376 DNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSRE---MKSQWTAVWVKISSSWI 432
Query: 363 CIAIYLWTLMAPCLFPDRDF 422
I +Y+WTL+AP + +RDF
Sbjct: 433 GIVLYVWTLVAPLVLTNRDF 452
>sp|Q9QZI8|SERC1_MOUSE Serine incorporator 1 (Tumor differentially expressed protein 2)
(Tumor differentially expressed 1 protein-like)
(Membrane protein TMS-2) (Axotomy-induced glyco/Golgi
protein 2)
Length = 453
Score = 130 bits (326), Expect = 3e-30
Identities = 66/138 (47%), Positives = 89/138 (64%), Gaps = 3/138 (2%)
Frame = +3
Query: 18 IVGLVIFLITVIYSSIRSRGHTSVGKLTMHGSETAILSDQESGVPVSKNQETG-QSVWDN 194
I+GLV+FL+ V YSSIR+ ++ V KLT+ E+ ++ D S + G DN
Sbjct: 318 IIGLVLFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGNGRSDGSLDDGDGIHRAVDN 377
Query: 195 EEDGVAYDYSFFHFMFFLGSLYVMMTLTNW--YQPSSNLMTLNANDASVWVKIVSSWLCI 368
E DGV Y YSFFHFM FL SLY+MMTLTNW Y+PS + + +VWVKI SSW+ +
Sbjct: 378 ERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSRE---MKSQWTAVWVKISSSWIGL 434
Query: 369 AIYLWTLMAPCLFPDRDF 422
+Y+WTL+AP + +RDF
Sbjct: 435 VLYVWTLVAPLVLTNRDF 452
>sp|Q8K0E7|SERC2_MOUSE Serine incorporator 2 (Tumor differentially expressed 2-like)
Length = 450
Score = 120 bits (301), Expect = 2e-27
Identities = 65/135 (48%), Positives = 81/135 (60%)
Frame = +3
Query: 18 IVGLVIFLITVIYSSIRSRGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNE 197
IVGLVIF++ + S+RS H V L M E Q+ V VS + +DNE
Sbjct: 322 IVGLVIFILCTFFISLRSSDHRQVNSL-MQTEECPAEMVQQQQVAVSDGR-----AYDNE 375
Query: 198 EDGVAYDYSFFHFMFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIY 377
+DGV Y YSFFHF L SL+VMMTLTNWY P + + SVWVKI +SW + +Y
Sbjct: 376 QDGVTYSYSFFHFCLVLASLHVMMTLTNWYSPGETRKMI-STWTSVWVKICASWAGLFLY 434
Query: 378 LWTLMAPCLFPDRDF 422
LWTL+AP L P+RDF
Sbjct: 435 LWTLVAPLLLPNRDF 449
>sp|Q96SA4|SERC2_HUMAN Serine incorporator 2 (Tumor differentially expressed 2-like)
Length = 456
Score = 114 bits (285), Expect = 2e-25
Identities = 62/142 (43%), Positives = 82/142 (57%), Gaps = 7/142 (4%)
Frame = +3
Query: 18 IVGLVIFLITVIYSSIRSRGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSV---- 185
IVGL+IFL+ ++ S+RS H V L + +E + Q+ Q V
Sbjct: 324 IVGLIIFLLCTLFISLRSSDHRQVNSL---------MQTEECPPMLDATQQQQQQVAACE 374
Query: 186 ---WDNEEDGVAYDYSFFHFMFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSS 356
+DNE+DGV Y YSFFHF L SL+VMMTLTNWY+P ++ A VWVKI +S
Sbjct: 375 GRAFDNEQDGVTYSYSFFHFCLVLASLHVMMTLTNWYKPGETRKMISTWTA-VWVKICAS 433
Query: 357 WLCIAIYLWTLMAPCLFPDRDF 422
W + +YLWTL+AP L +RDF
Sbjct: 434 WAGLLLYLWTLVAPLLLRNRDF 455
>sp|Q9HDY3|YK17_SCHPO Membrane protein PB1A10.07c
Length = 441
Score = 72.0 bits (175), Expect = 1e-12
Identities = 45/142 (31%), Positives = 71/142 (50%), Gaps = 9/142 (6%)
Frame = +3
Query: 18 IVGLVIFLITVIYSSIRSRGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNE 197
++G T++YS++R+ S + + +D + VS E G S E
Sbjct: 307 VIGAAFTFFTILYSAVRAASSRE-----SDDSYSYLYADSHD-MGVSTPLEDGSS----E 356
Query: 198 EDGVAYDYSF--FHFMFFLGSLYVMMTLTNW-----YQPSSN--LMTLNANDASVWVKIV 350
ED DY+F FH +F L + Y LTNW Y+ N + + + A+VWVKI+
Sbjct: 357 EDKHQSDYNFIWFHIVFVLAAFYTASLLTNWNTTSVYENQKNDVFVRIGFSYAAVWVKII 416
Query: 351 SSWLCIAIYLWTLMAPCLFPDR 416
+SW+C +Y+W+ +AP FP R
Sbjct: 417 TSWVCHGLYVWSCLAPVFFPYR 438
>sp|Q12116|TMS1_YEAST Membrane protein TMS1
Length = 473
Score = 65.9 bits (159), Expect = 7e-11
Identities = 31/78 (39%), Positives = 48/78 (61%), Gaps = 2/78 (2%)
Frame = +3
Query: 189 DNEEDGVAYDYSFFHFMFFLGSLYVMMTLT-NWYQPS-SNLMTLNANDASVWVKIVSSWL 362
D+E G Y+Y+ FH +FFL + ++ + LT N Q + + + WVKIVS+W+
Sbjct: 389 DDERTGTKYNYTLFHVIFFLATQWIAILLTINVTQDDVGDFIPVGRTYFYSWVKIVSAWI 448
Query: 363 CIAIYLWTLMAPCLFPDR 416
C A+Y WT++AP + PDR
Sbjct: 449 CYALYGWTVVAPAIMPDR 466
>sp|P16415|ZF36_HUMAN Zinc finger protein ZFP-36
Length = 582
Score = 31.6 bits (70), Expect = 1.5
Identities = 18/48 (37%), Positives = 24/48 (50%)
Frame = -1
Query: 157 DTGTPDSWSLNIAVSEPCIVNFPTLVWPLLRILE*ITVIRNITSPTIR 14
DT TP SW ++ E VNF W LL + ++ RN+ TIR
Sbjct: 26 DTRTPGSWEMDSVAFEDVAVNFTQEEWALLGPSQ-KSLYRNVMQETIR 72
>sp|P65374|MMLB_MYCTU Putative membrane protein mmpL11
sp|P65375|MMLB_MYCBO Putative membrane protein mmpL11
Length = 966
Score = 30.8 bits (68), Expect = 2.5
Identities = 11/45 (24%), Positives = 25/45 (55%)
Frame = +3
Query: 3 CLWTLIVGLVIFLITVIYSSIRSRGHTSVGKLTMHGSETAILSDQ 137
C W + G ++ L+ +Y ++ G+ + G + GS++ ++ DQ
Sbjct: 11 CRWLVFTGWLLALVPAVYLAMTQSGNLTGGGFEVAGSQSLLVHDQ 55
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,650,797
Number of Sequences: 369166
Number of extensions: 1313879
Number of successful extensions: 3169
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3101
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3158
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 4177115900
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)