Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_F10
(845 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13530|SERC3_HUMAN Serine incorporator 3 (Tumor differen... 253 4e-67
sp|Q9QZI9|SERC3_MOUSE Serine incorporator 3 (Tumor differen... 253 6e-67
sp|Q9NRX5|SERC1_HUMAN Serine incorporator 1 (Tumor differen... 249 5e-66
sp|Q9QZI8|SERC1_MOUSE Serine incorporator 1 (Tumor differen... 244 2e-64
sp|Q8K0E7|SERC2_MOUSE Serine incorporator 2 (Tumor differen... 213 4e-55
sp|Q96SA4|SERC2_HUMAN Serine incorporator 2 (Tumor differen... 213 7e-55
sp|Q9HDY3|YK17_SCHPO Membrane protein PB1A10.07c 123 6e-28
sp|Q12116|TMS1_YEAST Membrane protein TMS1 112 2e-24
sp|Q41706|UPSA3_VIGUN Probable ureide permease A3 (VuA3) 35 0.20
sp|P16415|ZF36_HUMAN Zinc finger protein ZFP-36 32 2.2
>sp|Q13530|SERC3_HUMAN Serine incorporator 3 (Tumor differentially expressed protein 1)
Length = 473
Score = 253 bits (647), Expect = 4e-67
Identities = 128/288 (44%), Positives = 179/288 (62%), Gaps = 7/288 (2%)
Frame = +2
Query: 2 FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
FILIQL+LLVDFAHSWNESW++ EE + + +Y L+ FT F
Sbjct: 171 FILIQLVLLVDFAHSWNESWVNRMEEGNPRLWYAALLSFTSAFYILSIICVGLLYTYYTK 230
Query: 182 YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
C NKFFIS N+ILCV+ S ISI P+I EH PRSGLLQSS++TLYT+YLTWSAM+N
Sbjct: 231 PDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSLITLYTMYLTWSAMSNE 290
Query: 362 SDKNCNPSLIVY-------TYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIY 520
D++CNP+L+ + T +T + T +P + S +GL +F++ ++Y
Sbjct: 291 PDRSCNPNLMSFITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLY 350
Query: 521 SSIRSSGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNEEDGVAYDYSFFHF 700
SSIR+S ++ V KLT+ GS++ IL D + + + DNE++GV Y YS FH
Sbjct: 351 SSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHL 410
Query: 701 MFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYL 844
M L SLY+MMTLT+WY P + ++ + +VWVKI SSW+C+ +Y+
Sbjct: 411 MLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSWVCLLLYV 458
>sp|Q9QZI9|SERC3_MOUSE Serine incorporator 3 (Tumor differentially expressed protein 1)
(Membrane protein TMS-1) (Axotomy-induced glycoprotein 1)
(Axotomy-induced glyco/Golgi protein 1) (AIGP-1)
Length = 472
Score = 253 bits (645), Expect = 6e-67
Identities = 130/290 (44%), Positives = 183/290 (63%), Gaps = 9/290 (3%)
Frame = +2
Query: 2 FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
FI+IQL+LLVD AHSWNE W++ EE + + +Y L+ FT F
Sbjct: 171 FIIIQLVLLVDMAHSWNELWVNRMEEGNPRLWYAALLSFTSLFYILSIVFAALLYVFYTK 230
Query: 182 YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
+C NK FIS N+I CV +S +SILP++ EH PRSGLLQSS++TLYT+YLTWSAMTN
Sbjct: 231 PDDCTENKVFISLNLIFCVAVSIVSILPKVQEHQPRSGLLQSSIITLYTLYLTWSAMTNE 290
Query: 362 SDKNCNPSLI-VYTYNTSKT------TGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIY 520
+++CNPSL+ + T+ TS T T + +P + S + I GL+IF+ +IY
Sbjct: 291 PERSCNPSLMSIITHLTSPTVSPANSTTLAPAYAPPSQSGHFMNLDDIWGLIIFVFCLIY 350
Query: 521 SSIRSSGHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQ--SVWDNEEDGVAYDYSFF 694
SS R+S ++ V KLT+ GS++ IL D +G + ++E GQ DNE++GV Y YSFF
Sbjct: 351 SSFRTSSNSQVNKLTLSGSDSVILGDTTNG---ANDEEDGQPRRAVDNEKEGVQYSYSFF 407
Query: 695 HFMFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYL 844
H M SLY+MMT+T+WY P + +++ +VW K+ SSWLC+ +YL
Sbjct: 408 HLMLCCASLYIMMTITSWYSPDAKFQKVSSKWLAVWFKMGSSWLCLLLYL 457
>sp|Q9NRX5|SERC1_HUMAN Serine incorporator 1 (Tumor differentially expressed protein 2)
(Tumor differentially expressed 1 protein-like)
Length = 453
Score = 249 bits (637), Expect = 5e-66
Identities = 136/287 (47%), Positives = 179/287 (62%), Gaps = 6/287 (2%)
Frame = +2
Query: 2 FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
FILIQL+LL+DFAHSWNESW++ EE +++ +Y L+ T
Sbjct: 163 FILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTH 222
Query: 182 YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
C+ NK FIS NM+LCV S +SILP+I E PRSGLLQSS++T+YT+YLTWSAMTN
Sbjct: 223 PASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNE 282
Query: 362 SDKNCNPSLI-VYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSS 538
+ NCNPSL+ + YNT+ +T+ S Q W I+GL++FL+ V YSSIR+S
Sbjct: 283 PETNCNPSLLSIIGYNTT------STVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTS 336
Query: 539 GHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVW---DNEEDGVAYDYSFFHFMFF 709
++ V KLT+ E+ ++ D G + E G V DNE DGV Y YSFFHFM F
Sbjct: 337 NNSQVNKLTLTSDESTLIED--GGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLF 394
Query: 710 LGSLYVMMTLTNW--YQPSSNLMTLNANDASVWVKIVSSWLCIAIYL 844
L SLY+MMTLTNW Y+PS + + +VWVKI SSW+ I +Y+
Sbjct: 395 LASLYIMMTLTNWYRYEPSRE---MKSQWTAVWVKISSSWIGIVLYV 438
>sp|Q9QZI8|SERC1_MOUSE Serine incorporator 1 (Tumor differentially expressed protein 2)
(Tumor differentially expressed 1 protein-like)
(Membrane protein TMS-2) (Axotomy-induced glyco/Golgi
protein 2)
Length = 453
Score = 244 bits (624), Expect = 2e-64
Identities = 133/285 (46%), Positives = 176/285 (61%), Gaps = 4/285 (1%)
Frame = +2
Query: 2 FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
FILIQL+LL+DFAHSWNESW++ EE +++ +Y L+ T
Sbjct: 163 FILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAVVLFFVYYTH 222
Query: 182 YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
CA NK FIS NM+LC+ S +SILP+I E PRSGLLQSS++T+YT+YLTWSAMTN
Sbjct: 223 PASCAENKAFISVNMLLCIGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNE 282
Query: 362 SDKNCNPSLI-VYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSS 538
+ NCNPSL+ + +NT++ I S Q W I+GLV+FL+ V YSSIR+S
Sbjct: 283 PETNCNPSLLSIIGFNTTR------PIPKDGQSVQWWHPQGIIGLVLFLLCVFYSSIRTS 336
Query: 539 GHTSVGKLTMHGSETAILSDQESGVPVSKNQETG-QSVWDNEEDGVAYDYSFFHFMFFLG 715
++ V KLT+ E+ ++ D S + G DNE DGV Y YSFFHFM FL
Sbjct: 337 NNSQVNKLTLTSDESTLIEDGNGRSDGSLDDGDGIHRAVDNERDGVTYSYSFFHFMLFLA 396
Query: 716 SLYVMMTLTNW--YQPSSNLMTLNANDASVWVKIVSSWLCIAIYL 844
SLY+MMTLTNW Y+PS + + +VWVKI SSW+ + +Y+
Sbjct: 397 SLYIMMTLTNWYRYEPSRE---MKSQWTAVWVKISSSWIGLVLYV 438
>sp|Q8K0E7|SERC2_MOUSE Serine incorporator 2 (Tumor differentially expressed 2-like)
Length = 450
Score = 213 bits (543), Expect = 4e-55
Identities = 122/281 (43%), Positives = 157/281 (55%)
Frame = +2
Query: 2 FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
FILIQLIL VDFAHSWN+ W+ EE D+ A+Y GL FFT F
Sbjct: 170 FILIQLILFVDFAHSWNQRWLCKAEECDSPAWYAGLFFFTFLFYLLSIAAVALMFVYYTE 229
Query: 182 YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
C K FIS N+ CV +S I++LP++ + P SGLLQ+S++TLYT+++TWSA++N
Sbjct: 230 SGACHEGKVFISLNLTFCVCVSIIAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSNV 289
Query: 362 SDKNCNPSLIVYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSSG 541
D+ CNP L T TG + S W IVGLVIF++ + S+RSS
Sbjct: 290 PDQKCNPHL-----PTKNGTGQ---VDLEDYSTVWWDAPSIVGLVIFILCTFFISLRSSD 341
Query: 542 HTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNEEDGVAYDYSFFHFMFFLGSL 721
H V L M E Q+ V VS + +DNE+DGV Y YSFFHF L SL
Sbjct: 342 HRQVNSL-MQTEECPAEMVQQQQVAVSDGR-----AYDNEQDGVTYSYSFFHFCLVLASL 395
Query: 722 YVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYL 844
+VMMTLTNWY P + + SVWVKI +SW + +YL
Sbjct: 396 HVMMTLTNWYSPGETRKMI-STWTSVWVKICASWAGLFLYL 435
>sp|Q96SA4|SERC2_HUMAN Serine incorporator 2 (Tumor differentially expressed 2-like)
Length = 456
Score = 213 bits (541), Expect = 7e-55
Identities = 116/288 (40%), Positives = 161/288 (55%), Gaps = 7/288 (2%)
Frame = +2
Query: 2 FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
FILIQL+LL+DFAHSWN+ W+ EE D++A+Y GL FFT+ F
Sbjct: 170 FILIQLVLLIDFAHSWNQRWLGKAEECDSRAWYAGLFFFTLLFYLLSIAAVALMFMYYTE 229
Query: 182 YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
C K FIS N+ CV +S ++LP++ + P SGLLQ+S++TLYT+++TWSA+++
Sbjct: 230 PSGCHEGKVFISLNLTFCVCVSIAAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSSI 289
Query: 362 SDKNCNPSLIVYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSSG 541
++ CNP L N + G P Q W IVGL+IFL+ ++ S+RSS
Sbjct: 290 PEQKCNPHLPTQLGNETVVAG------PEGYETQWWDAPSIVGLIIFLLCTLFISLRSSD 343
Query: 542 HTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSV-------WDNEEDGVAYDYSFFHF 700
H V L + +E + Q+ Q V +DNE+DGV Y YSFFHF
Sbjct: 344 HRQVNSL---------MQTEECPPMLDATQQQQQQVAACEGRAFDNEQDGVTYSYSFFHF 394
Query: 701 MFFLGSLYVMMTLTNWYQPSSNLMTLNANDASVWVKIVSSWLCIAIYL 844
L SL+VMMTLTNWY+P ++ A VWVKI +SW + +YL
Sbjct: 395 CLVLASLHVMMTLTNWYKPGETRKMISTWTA-VWVKICASWAGLLLYL 441
>sp|Q9HDY3|YK17_SCHPO Membrane protein PB1A10.07c
Length = 441
Score = 123 bits (309), Expect = 6e-28
Identities = 90/291 (30%), Positives = 138/291 (47%), Gaps = 10/291 (3%)
Frame = +2
Query: 2 FILIQLILLVDFAHSWNESWIDGYEENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXXG 181
FI+ L+LLVDFAH+W E +D +D+ + F LI TV
Sbjct: 167 FIVYGLMLLVDFAHTWAERCVDRVLTSDSSSSKFYLIGSTVGMYVVGLVLTILTYVFFCA 226
Query: 182 YPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTNG 361
C+ N+ + N++LC+ +S +S+ P I E+ PRSGL QSSM+ YT YL SA+ N
Sbjct: 227 -SSCSFNQAINTINLLLCIAVSCLSVHPTIQEYNPRSGLAQSSMVMCYTCYLILSALANR 285
Query: 362 SDK-NCNPSLIVYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRSS 538
D+ CNP G + S ++ ++G T++YS++R++
Sbjct: 286 PDEGQCNP--------------WGNSASGTR------EFSKVIGAAFTFFTILYSAVRAA 325
Query: 539 GHTSVGKLTMHGSETAILSDQESGVPVSKNQETGQSVWDNEEDGVAYDYSF--FHFMFFL 712
S + + +D + VS E G S EED DY+F FH +F L
Sbjct: 326 SSRE-----SDDSYSYLYADSHD-MGVSTPLEDGSS----EEDKHQSDYNFIWFHIVFVL 375
Query: 713 GSLYVMMTLTNW-----YQPSSN--LMTLNANDASVWVKIVSSWLCIAIYL 844
+ Y LTNW Y+ N + + + A+VWVKI++SW+C +Y+
Sbjct: 376 AAFYTASLLTNWNTTSVYENQKNDVFVRIGFSYAAVWVKIITSWVCHGLYV 426
>sp|Q12116|TMS1_YEAST Membrane protein TMS1
Length = 473
Score = 112 bits (279), Expect = 2e-24
Identities = 83/317 (26%), Positives = 146/317 (46%), Gaps = 37/317 (11%)
Frame = +2
Query: 2 FILIQLILLVDFAHSWNESWIDGYE-ENDNKAYYFGLIFFTVFFXXXXXXXXXXXXXXXX 178
FIL+ LILLVDFAH W E+ I E E+++ +++ +
Sbjct: 158 FILVGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMF 217
Query: 179 GYPECALNKFFISFNMILCVMMSAISILPRIHEHMPRSGLLQSSMLTLYTIYLTWSAMTN 358
+ +C +N+ ++ N+IL V+ +S+ P+I E P+SGL QSSM+++Y YLT SAM++
Sbjct: 218 CHQQCNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMSS 277
Query: 359 -GSDKNCNPSLIVYTYNTSKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIRS 535
DK CNP +V + T K +++I+G + I + Y++ R+
Sbjct: 278 EPDDKMCNP--LVRSSGTRK-------------------FSIILGSLFTFIAIAYTTTRA 316
Query: 536 SGHTSVGKLTMHGS----------------------ETAILSDQESGVPVSKNQETG--- 640
+ +++ +G+ E + +E +P S +T
Sbjct: 317 AANSAFQGTNTNGAIYLGNDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLG 376
Query: 641 ----QSVWDNEED----GVAYDYSFFHFMFFLGS--LYVMMTLTNWYQPSSNLMTLNAND 790
DN+ D G Y+Y+ FH +FFL + + +++T+ + + +
Sbjct: 377 TSSPTGAMDNQNDDERTGTKYNYTLFHVIFFLATQWIAILLTINVTQDDVGDFIPVGRTY 436
Query: 791 ASVWVKIVSSWLCIAIY 841
WVKIVS+W+C A+Y
Sbjct: 437 FYSWVKIVSAWICYALY 453
>sp|Q41706|UPSA3_VIGUN Probable ureide permease A3 (VuA3)
Length = 376
Score = 35.4 bits (80), Expect = 0.20
Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Frame = +2
Query: 410 SKTTGMGTTISPVTNSEQNWSWTLIVGLVIFLITVIYSSIR---SSGHTSVGKLTMHGSE 580
S T +GTT++ + + N + L G+ FLI V R S+ + KL+ + S+
Sbjct: 119 SITVVIGTTLNYFLDDKINKAEILFPGVGCFLIAVFLGFCRFNSSNASDNKAKLSNYTSD 178
Query: 581 --TAILSDQESGVPVSKNQETGQSVWDNEEDGVA 676
+S +ES + SK+ E G S DN E G A
Sbjct: 179 YKEVAISSKESDLVKSKDLERGSSSADNVEAGTA 212
>sp|P16415|ZF36_HUMAN Zinc finger protein ZFP-36
Length = 582
Score = 32.0 bits (71), Expect = 2.2
Identities = 18/48 (37%), Positives = 25/48 (52%)
Frame = -3
Query: 621 DTGTPDSWSLNIAVSEPCIVNFPTLVWPLLRILE*ITVIRNITRPTIR 478
DT TP SW ++ E VNF W LL + ++ RN+ + TIR
Sbjct: 26 DTRTPGSWEMDSVAFEDVAVNFTQEEWALLGPSQ-KSLYRNVMQETIR 72
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,237,248
Number of Sequences: 369166
Number of extensions: 2095460
Number of successful extensions: 5173
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4951
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5141
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8293644780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)