Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01103 (928 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q91XW8|FKBP6_MOUSE FK506-binding protein 6 (Peptidyl-pro... 112 1e-24 sp|O75344|FKBP6_HUMAN FK506-binding protein 6 (Peptidyl-pro... 104 3e-22 sp|Q38931|FKB70_ARATH 70 kDa peptidylprolyl isomerase (Pept... 65 3e-10 sp|Q02790|FKBP4_HUMAN FK506-binding protein 4 (Peptidyl-pro... 59 2e-08 sp|Q43207|FKB70_WHEAT 70 kDa peptidylprolyl isomerase (Pept... 59 2e-08 sp|P27124|FKBP4_RABIT FK506-binding protein 4 (Peptidyl-pro... 59 3e-08 sp|Q13451|FKBP5_HUMAN FK506-binding protein 5 (Peptidyl-pro... 55 4e-07 sp|Q64378|FKBP5_MOUSE FK506-binding protein 5 (Peptidyl-pro... 55 4e-07 sp|Q5RF88|FKBP5_PONPY FK506-binding protein 5 (Peptidyl-pro... 55 4e-07 sp|Q9XT11|FKBP5_AOTNA FK506-binding protein 5 (Peptidyl-pro... 54 5e-07
>sp|Q91XW8|FKBP6_MOUSE FK506-binding protein 6 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506 binding protein) (FKBP-36) (Immunophilin FKBP36) Length = 327 Score = 112 bits (280), Expect = 1e-24 Identities = 69/221 (31%), Positives = 116/221 (52%) Frame = +3 Query: 225 YKNIASKMTDISGGQKLIFKRLISKGEGSKAPEGSLVIYNYKFYCEPEPEPFDSTRFKKR 404 Y+ ++ +M DISG + ++ K +I +G G + V+ Y Y E +PFDS F+K Sbjct: 22 YERLSQRMLDISGDRGVL-KDIIREGTGDTVTPDASVLVKYSGYLEHMDKPFDSNCFRKT 80 Query: 405 PDRQRVGVGQLLPGLDVALQSMSRKERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVI 584 P ++G L G+++ L SM + E A F+F + +G LG PP IP A + EIE+I Sbjct: 81 PRLMKLGEDITLWGMELGLLSMRKGELARFLFKPAYAYGTLGCPPLIPPNATVLFEIELI 140 Query: 585 DFTEKNLIDDFFEKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRGLDI 764 DF + D F + E++ + ++K+ R+ N R RF A +Y+R L + Sbjct: 141 DFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLL 200 Query: 765 LYSMPICTDDEERIRSGHVTKLHLNMAHCNLKLNRGPSAIK 887 L+ + T +E+ + V + LN++ LKL+R A++ Sbjct: 201 LHRR-LATCEEQHLVEPAVLLVLLNLSFVYLKLDRPAMALR 240
>sp|O75344|FKBP6_HUMAN FK506-binding protein 6 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (36 kDa FK506 binding protein) (FKBP-36) (Immunophilin FKBP36) Length = 327 Score = 104 bits (260), Expect = 3e-22 Identities = 66/220 (30%), Positives = 111/220 (50%) Frame = +3 Query: 225 YKNIASKMTDISGGQKLIFKRLISKGEGSKAPEGSLVIYNYKFYCEPEPEPFDSTRFKKR 404 Y+ ++ +M DISG + ++ K +I +G G + V+ Y Y E PFDS F+K Sbjct: 22 YERLSQRMLDISGDRGVL-KDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKT 80 Query: 405 PDRQRVGVGQLLPGLDVALQSMSRKERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVI 584 P ++G L G+++ L SM R E A F+F + +G LG PP IP + EIE++ Sbjct: 81 PRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELL 140 Query: 585 DFTEKNLIDDFFEKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRGLDI 764 DF + D F + E++ + ++K+ R+ N R RF A +Y+R L + Sbjct: 141 DFLDCAESDKFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLL 200 Query: 765 LYSMPICTDDEERIRSGHVTKLHLNMAHCNLKLNRGPSAI 884 L +++ + + + L LN++ LKL+R A+ Sbjct: 201 LRRRSAPPEEQHLVEAAKLPVL-LNLSFTYLKLDRPTIAL 239
>sp|Q38931|FKB70_ARATH 70 kDa peptidylprolyl isomerase (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (Peptidylprolyl isomerase ROF1) Length = 551 Score = 65.1 bits (157), Expect = 3e-10 Identities = 37/130 (28%), Positives = 69/130 (53%) Frame = +3 Query: 195 NDPDSVDFPSYKNIASKMTDISGGQKLIFKRLISKGEGSKAPEGSLVIYNYKFYCEPEPE 374 ND D +DF + K+ + Q+ + K+L+ +GEG + PE + + + Sbjct: 14 NDDDDMDFGDGASFL-KVGEEKEIQQGLKKKLLKEGEGYETPENGDEVEVHYTGTLLDGT 72 Query: 375 PFDSTRFKKRPDRQRVGVGQLLPGLDVALQSMSRKERAHFVFDSSVMFGELGVPPRIPER 554 FDS+R + P + +G GQ++ G D+ +++M + E A F + + +GE G PP IP Sbjct: 73 KFDSSRDRATPFKFTLGQGQVIKGWDIGIKTMKKGENAVFTIPAELAYGESGSPPTIPAN 132 Query: 555 ADIYAEIEVI 584 A + ++E++ Sbjct: 133 ATLQFDVELL 142
Score = 50.4 bits (119), Expect = 7e-06 Identities = 58/259 (22%), Positives = 116/259 (44%), Gaps = 19/259 (7%) Frame = +3 Query: 207 SVDFPSYKNIASKMTDISGGQKLIFKRLISKGEGSKAP-EGSLV------------IYNY 347 +++ S+K + S++TD + K+++ +G+G + P EG++V ++ Sbjct: 255 NLELVSWKTV-SEVTD----DNKVVKKVLKEGDGYERPNEGAVVKVKLIGKLQDGTVFLK 309 Query: 348 KFYCEPEPEPFDSTRFKKRPDRQRVGVGQLLPGLDVALQSMSRKERAHFVFDSSVMFG-- 521 K + E E EPF+ FK + Q++ GLD A+ M + E A D FG Sbjct: 310 KGHGENE-EPFE---FKTDEE-------QVVDGLDRAVMKMKKGEVALVTIDPEYAFGSN 358 Query: 522 ----ELGVPPRIPERADIYAEIEVIDFTEKNLIDDFFEKTVEERLELSFSDMIKLVIQCR 689 EL V +P + + E++++ F ++ + ++ EE++E + + Sbjct: 359 ESQQELAV---VPPNSTVTYEVDLLTFDKER---ESWDMNTEEKIEAASKK--------K 404 Query: 690 DDANVAVRDKRFGGALNKYQRGLDILYSMPICTDDEERIRSGHVTKLHLNMAHCNLKLNR 869 ++ N + ++ A +Y++ + + +++E++ +LN A C LKL Sbjct: 405 EEGNSKFKGGKYSLASKRYEKAVKFIEYDTSFSEEEKKQAKALKVACNLNDAACKLKLKD 464 Query: 870 GPSAIKCCNVVLGKQPHNV 926 A K C VL + NV Sbjct: 465 YKQAEKLCTKVLELESTNV 483
>sp|Q02790|FKBP4_HUMAN FK506-binding protein 4 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506 binding protein) (FKBP59) Length = 459 Score = 58.9 bits (141), Expect = 2e-08 Identities = 57/222 (25%), Positives = 104/222 (46%), Gaps = 6/222 (2%) Frame = +3 Query: 276 IFKRLISKGEGSKAP-EGSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGVGQLLP--- 443 I +R+ ++GEG P EG++V + Y + F +R R +G G+ L Sbjct: 150 IIRRIQTRGEGYAKPNEGAIVEVALEGY-------YKDKLFDQRELRFEIGEGENLDLPY 202 Query: 444 GLDVALQSMSRKERAHFVFDSSVMFGELGVPP-RIPERADIYAEIEVIDFTEKNLIDDFF 620 GL+ A+Q M + E + S FG +G +IP A++ E+ + F + + + Sbjct: 203 GLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAK---ESW 259 Query: 621 EKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRGLDIL-YSMPICTDDE 797 E EE+LE S ++ V ++ ++ AL +Y++ + L Y ++ Sbjct: 260 EMNSEEKLEQSTI--------VKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEA 311 Query: 798 ERIRSGHVTKLHLNMAHCNLKLNRGPSAIKCCNVVLGKQPHN 923 ++ ++ + HLN+A C+LKL +AI+ CN L +N Sbjct: 312 QKAQALRLAS-HLNLAMCHLKLQAFSAAIESCNKALELDSNN 352
Score = 47.8 bits (112), Expect = 4e-05 Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 6/119 (5%) Frame = +3 Query: 276 IFKRLISKGEGSKAPE-GSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQR-----VGVGQL 437 + K + +G G++ P G V +Y + D T+F DR+ +G G++ Sbjct: 33 VLKVIKREGTGTEMPMIGDRVFVHYTGWL------LDGTKFDSSLDRKDKFSFDLGKGEV 86 Query: 438 LPGLDVALQSMSRKERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVIDFTEKNLIDD 614 + D+A+ +M E H +G G PP+IP A + E+E+ +F ++L ++ Sbjct: 87 IKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEE 145
>sp|Q43207|FKB70_WHEAT 70 kDa peptidylprolyl isomerase (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 559 Score = 58.9 bits (141), Expect = 2e-08 Identities = 35/128 (27%), Positives = 70/128 (54%), Gaps = 3/128 (2%) Frame = +3 Query: 264 GQKLIFKRLISKGEGSKAPEGSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGVGQLLP 443 G++ + K+L+ +GEG PE + + + + FDS+R + + ++G GQ++ Sbjct: 39 GKQGLKKKLLKEGEGWDTPEVGDEVEVHYTGTLLDGKKFDSSRDRDDTFKFKLGQGQVIK 98 Query: 444 GLDVALQSMSRKERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVIDFTE-KNLIDD-- 614 G D +++M + E A F + +GE G PP IP A + ++E++ +T +++ D Sbjct: 99 GWDQGIKTMKKGENALFTIPPELAYGESGSPPTIPANATLQFDVELLSWTSVRDIAKDGG 158 Query: 615 FFEKTVEE 638 F+K ++E Sbjct: 159 IFKKILKE 166
Score = 51.2 bits (121), Expect = 4e-06 Identities = 54/238 (22%), Positives = 101/238 (42%), Gaps = 16/238 (6%) Frame = +3 Query: 261 GGQKLIFKRLISKGEGSKAP-EGSLV------------IYNYKFYCEPEPEPFDSTRFKK 401 G K I K+++ + EG + P EG++V ++ K + E EP F+ Sbjct: 271 GDDKKILKKVLKEXEGYERPNEGAVVTVKITGKLQDGTVFLKKGHDEQEP-------FEF 323 Query: 402 RPDRQRVGVGQLLPGLDVALQSMSRKERAHFVFDSSVMFG--ELGVPPRIPERADIYAEI 575 + D + V + GLD A+ +M + E A +G E +P + + E+ Sbjct: 324 KTDEEAV-----IEGLDRAVLNMKKGEVALVTIPPEYAYGSTESKQDAIVPPNSTVIYEV 378 Query: 576 EVIDFTEKNLIDDFFEKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRG 755 E++ F + +E +L+ S+ I+ +++ N + ++ A +Y++ Sbjct: 379 ELVSFVKD-----------KESWDLNNSEKIEAAGTKKEEGNALFKSGKYARASKRYEKA 427 Query: 756 LDIL-YSMPICTDDEERIRSGHVTKLHLNMAHCNLKLNRGPSAIKCCNVVLGKQPHNV 926 + Y D++++ + +T +LN A C LKL A K C VL NV Sbjct: 428 AKFIEYDTSFSEDEKKQSKQLKIT-CNLNNAACKLKLKDYKQAEKLCTKVLELDSRNV 484
>sp|P27124|FKBP4_RABIT FK506-binding protein 4 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506 binding protein) (FKBP59) Length = 458 Score = 58.5 bits (140), Expect = 3e-08 Identities = 59/230 (25%), Positives = 108/230 (46%), Gaps = 6/230 (2%) Frame = +3 Query: 252 DISGGQKLIFKRLISKGEGSKAP-EGSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGV 428 D GG I +R+ ++GEG P +G++V + Y + F +R R VG Sbjct: 145 DEDGG---IIRRIRTRGEGYARPNDGAIVEVALEGY-------YKDRLFDQRELRFEVGE 194 Query: 429 GQLLP---GLDVALQSMSRKERAHFVFDSSVMFGELGVPP-RIPERADIYAEIEVIDFTE 596 G+ L GL+ A+Q M + E + S FG G +IP A++ E+ + F + Sbjct: 195 GESLDLPCGLEKAIQRMEKGEHSILYLKPSYAFGNAGKEKFQIPPYAELKYEVHLKSFEK 254 Query: 597 KNLIDDFFEKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRGLDIL-YS 773 + +E + EE+LE S ++ V ++ ++ AL +Y++ + L Y Sbjct: 255 AK---ESWEMSSEEKLEQSAI--------VKERGTVYFKEGKYKQALLQYKKIVSWLEYE 303 Query: 774 MPICTDDEERIRSGHVTKLHLNMAHCNLKLNRGPSAIKCCNVVLGKQPHN 923 +++ ++ ++ + HLN+A C+LKL +A++ CN L +N Sbjct: 304 SSFSSEEVQKAQALRLAS-HLNLAMCHLKLQAFSAAVESCNKALELDSNN 352
Score = 48.1 bits (113), Expect = 3e-05 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 6/119 (5%) Frame = +3 Query: 276 IFKRLISKGEGSKAPE-GSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQR-----VGVGQL 437 + K + +G G++ P G V +Y + D T+F DR+ +G G++ Sbjct: 33 VLKVIKREGTGTETPMIGDRVFVHYTGWL------LDGTKFDSSLDRKDKFSFDLGKGEV 86 Query: 438 LPGLDVALQSMSRKERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVIDFTEKNLIDD 614 + D+A+ +M E +G G PP+IP A + E+E+ +F ++L DD Sbjct: 87 IKAWDIAVATMKVGELCRITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTDD 145
>sp|Q13451|FKBP5_HUMAN FK506-binding protein 5 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-binding immunophilin) (Androgen-regulated protein 6) Length = 457 Score = 54.7 bits (130), Expect = 4e-07 Identities = 34/129 (26%), Positives = 64/129 (49%), Gaps = 2/129 (1%) Frame = +3 Query: 234 IASKMTDISGGQKLIFKRLISK-GEGSKAPE-GSLVIYNYKFYCEPEPEPFDSTRFKKRP 407 +A + DI+ + +++ + G G + P G V +YK + FDS+ + P Sbjct: 18 VAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS-NGKKFDSSHDRNEP 76 Query: 408 DRQRVGVGQLLPGLDVALQSMSRKERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVID 587 +G GQ++ D+ + +M + E H + +G G P+IP A ++ EIE++D Sbjct: 77 FVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLD 136 Query: 588 FTEKNLIDD 614 F ++L +D Sbjct: 137 FKGEDLFED 145
Score = 50.1 bits (118), Expect = 9e-06 Identities = 52/221 (23%), Positives = 89/221 (40%), Gaps = 5/221 (2%) Frame = +3 Query: 276 IFKRLISKGEGSKAP-EGSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGVGQ---LLP 443 I +R KGEG P EG+ V + + C F R VG G+ + Sbjct: 148 IIRRTKRKGEGYSNPNEGATVEIHLEGRC-------GGRMFDCRDVAFTVGEGEDHDIPI 200 Query: 444 GLDVALQSMSRKERAHFVFDSSVMFGELGVPP-RIPERADIYAEIEVIDFTEKNLIDDFF 620 G+D AL+ M R+E+ FGE G P I A++ E+ + F + Sbjct: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK-------- 252 Query: 621 EKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRGLDILYSMPICTDDEE 800 +E E+ + ++ ++ V + ++ A+ +Y + + L ++ E Sbjct: 253 ---AKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKES 309 Query: 801 RIRSGHVTKLHLNMAHCNLKLNRGPSAIKCCNVVLGKQPHN 923 + + LN+A C LKL A++CC+ LG N Sbjct: 310 KASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSAN 350
>sp|Q64378|FKBP5_MOUSE FK506-binding protein 5 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP-51) Length = 456 Score = 54.7 bits (130), Expect = 4e-07 Identities = 31/106 (29%), Positives = 55/106 (51%), Gaps = 1/106 (0%) Frame = +3 Query: 300 GEGSKAPE-GSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGVGQLLPGLDVALQSMSR 476 G +AP G V +YK + + FDS+ +K+P +G GQ++ D+ + +M + Sbjct: 41 GTSDEAPMFGDKVYVHYKGMLS-DGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKK 99 Query: 477 KERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVIDFTEKNLIDD 614 E H + +G G +IP A ++ EIE++DF ++L +D Sbjct: 100 GEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFKGEDLFED 145
Score = 48.1 bits (113), Expect = 3e-05 Identities = 51/221 (23%), Positives = 89/221 (40%), Gaps = 5/221 (2%) Frame = +3 Query: 276 IFKRLISKGEGSKAP-EGSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGVGQ---LLP 443 + +R+ KGEG P EG+ V + + C F R VG G+ + Sbjct: 148 VIRRIKRKGEGYSNPNEGATVKVHLEGCC-------GGRTFDCRDVVFVVGEGEDHDIPI 200 Query: 444 GLDVALQSMSRKERAHFVFDSSVMFGELGVPP-RIPERADIYAEIEVIDFTEKNLIDDFF 620 G+D AL M R+E+ FGE G P I A++ E+ + F + Sbjct: 201 GIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEK-------- 252 Query: 621 EKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRGLDILYSMPICTDDEE 800 +E E+ + + ++ V + ++ A+ +Y++ + L ++ E Sbjct: 253 ---AKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKES 309 Query: 801 RIRSGHVTKLHLNMAHCNLKLNRGPSAIKCCNVVLGKQPHN 923 + + LN+A C LKL A++CC+ LG N Sbjct: 310 KASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSAN 350
>sp|Q5RF88|FKBP5_PONPY FK506-binding protein 5 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) Length = 457 Score = 54.7 bits (130), Expect = 4e-07 Identities = 34/129 (26%), Positives = 64/129 (49%), Gaps = 2/129 (1%) Frame = +3 Query: 234 IASKMTDISGGQKLIFKRLISK-GEGSKAPE-GSLVIYNYKFYCEPEPEPFDSTRFKKRP 407 +A + DI+ + +++ + G G + P G V +YK + FDS+ + P Sbjct: 18 VAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS-NGKKFDSSHDRNEP 76 Query: 408 DRQRVGVGQLLPGLDVALQSMSRKERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVID 587 +G GQ++ D+ + +M + E H + +G G P+IP A ++ EIE++D Sbjct: 77 FVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLD 136 Query: 588 FTEKNLIDD 614 F ++L +D Sbjct: 137 FKGEDLFED 145
Score = 48.9 bits (115), Expect = 2e-05 Identities = 52/221 (23%), Positives = 90/221 (40%), Gaps = 5/221 (2%) Frame = +3 Query: 276 IFKRLISKGEGSKAP-EGSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGVGQ--LLP- 443 I +R KGEG P EG+ V + + C F R VG G+ ++P Sbjct: 148 IIRRTKRKGEGYSNPNEGATVEIHLEGRC-------GGRMFDCRDVAFTVGEGEDHVIPI 200 Query: 444 GLDVALQSMSRKERAHFVFDSSVMFGELGVPP-RIPERADIYAEIEVIDFTEKNLIDDFF 620 G+D AL+ M R+E+ FGE G P I A++ E+ + F + Sbjct: 201 GIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK-------- 252 Query: 621 EKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRGLDILYSMPICTDDEE 800 +E E+ + ++ ++ V + ++ A+ +Y + + L ++ E Sbjct: 253 ---AKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKES 309 Query: 801 RIRSGHVTKLHLNMAHCNLKLNRGPSAIKCCNVVLGKQPHN 923 + + LN+A C KL A++CC+ LG N Sbjct: 310 KASESFLLAAFLNLAMCYSKLREYTKAVECCDKALGLDSAN 350
>sp|Q9XT11|FKBP5_AOTNA FK506-binding protein 5 (Peptidyl-prolyl cis-trans isomerase) (51 kDa FK506-binding immunophilin) (FKBP-51) Length = 457 Score = 54.3 bits (129), Expect = 5e-07 Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 3/108 (2%) Frame = +3 Query: 300 GEGSKAP---EGSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGVGQLLPGLDVALQSM 470 G G + P + V YN K + FDS+ + P +G GQ++ D+ + +M Sbjct: 41 GHGEETPMIGDKVYVHYNGKL---SNGKKFDSSHDRNEPFVFSIGKGQVIKAWDIGVATM 97 Query: 471 SRKERAHFVFDSSVMFGELGVPPRIPERADIYAEIEVIDFTEKNLIDD 614 + E H + +G G P+IP A ++ EIE++DF ++L++D Sbjct: 98 KKGEICHLLCKPEYAYGATGSLPKIPSNATLFFEIELLDFKGEDLLED 145
Score = 45.8 bits (107), Expect = 2e-04 Identities = 50/221 (22%), Positives = 89/221 (40%), Gaps = 5/221 (2%) Frame = +3 Query: 276 IFKRLISKGEGSKAP-EGSLVIYNYKFYCEPEPEPFDSTRFKKRPDRQRVGVGQ---LLP 443 I +R +GEG P EG+ V + + C F R VG G+ + Sbjct: 148 IIRRTKRRGEGYSNPNEGARVQIHLEGRC-------GGRVFDCRDVAFTVGEGEDHDIPI 200 Query: 444 GLDVALQSMSRKERAHFVFDSSVMFGELGVPP-RIPERADIYAEIEVIDFTEKNLIDDFF 620 G+D AL+ M R+E+ FGE G P I A++ E+ + F + Sbjct: 201 GIDKALEKMQREEQCILHLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEK-------- 252 Query: 621 EKTVEERLELSFSDMIKLVIQCRDDANVAVRDKRFGGALNKYQRGLDILYSMPICTDDEE 800 +E E+ + ++ ++ + + ++ A+ +Y + + L ++ E Sbjct: 253 ---AKESWEMDTKEKLEQAAIVKEKGTLYFKGGKYVQAVIQYGKIVSWLEMEYGLSEKES 309 Query: 801 RIRSGHVTKLHLNMAHCNLKLNRGPSAIKCCNVVLGKQPHN 923 + + LN+A C LKL A++CC+ LG N Sbjct: 310 KASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSAN 350
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 93,428,774 Number of Sequences: 369166 Number of extensions: 1877249 Number of successful extensions: 5338 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5071 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5311 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9510757740 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)