Planaria EST Database

DrC_01082

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01082
         (905 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9NX52|RHBD2_HUMAN  Rhomboid-related protein 2 (RRP2) (Rh...   192   8e-49
sp|P58872|RHBD4_HUMAN  Rhomboid-related protein 4 (Ventrhoid...   167   5e-41
sp|P58873|RHBD4_MOUSE  Rhomboid-related protein 4 (Ventrhoid...   164   2e-40
sp|Q19821|ROM1_CAEEL  Rhomboid related protein 1                  163   7e-40
sp|P20350|RHOM_DROME  Rhomboid protein (Veinlet protein)          159   1e-38
sp|Q8VC82|RHBD1_MOUSE  Rhomboid-related protein 1 (RRP) (Rho...   158   2e-38
sp|O75783|RHB1_HUMAN  Rhomboid-related protein 1 (RRP) (Rhom...   158   2e-38
sp|P34356|ROM2_CAEEL  Rhomboid related protein 2                  144   4e-34
sp|O88779|RHBD1_RAT  Rhomboid-related protein 1 (RRP) (Rhomb...   107   5e-23
sp|P54493|YQGP_BACSU  Hypothetical protein yqgP                    49   3e-05

>sp|Q9NX52|RHBD2_HUMAN Rhomboid-related protein 2 (RRP2) (Rhomboid-like protein 2)
          Length = 303

 Score =  192 bits (489), Expect = 8e-49
 Identities = 107/257 (41%), Positives = 151/257 (58%), Gaps = 1/257 (0%)
 Frame = +2

Query: 2   YSEAYDCKPPPFIIPLITLSQIGVFIYYAIKLNTDTDKTNDVTARSGVHLRSPLIYSPYR 181
           Y E  +C PPP  I  I+L+++ VFIYYA+       +   +T  +G+ L SP IYSP +
Sbjct: 62  YLERANCFPPPVFIISISLAELAVFIYYAVW----KPQKQWITLDTGI-LESPFIYSPEK 116

Query: 182 RIQAWRFIGYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSC 361
           R +AWRFI YM +H G  H++ N  MQLVLG  LE+VHK  RVG+VY+ GV+AGSLA S 
Sbjct: 117 REEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHKGLRVGLVYLAGVIAGSLASSI 176

Query: 362 FDATKYLVGASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGG 541
           FD  +YLVGASGG YAL+G +F  ++ N+  M            +  +FRL+++ L+   
Sbjct: 177 FDPLRYLVGASGGVYALMGGYFMNVLVNFQEM----------IPAFGIFRLLIIILIIVL 226

Query: 542 DTGIAIYDR-FAKEVPTPIGFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWISLALYC 718
           D G A+Y R F  E  +P+ F+AH  G  AG  IG  V    +    +   FWI++A Y 
Sbjct: 227 DMGFALYRRFFVPEDGSPVSFAAHIAGGFAGMSIGYTVFSCFDKALLKDPRFWIAIAAYL 286

Query: 719 LFMIGAIVFNVICASKN 769
             ++ A+ FN+  +  N
Sbjct: 287 ACVLFAVFFNIFLSPAN 303

>sp|P58872|RHBD4_HUMAN Rhomboid-related protein 4 (Ventrhoid transmembrane protein)
          Length = 404

 Score =  167 bits (422), Expect = 5e-41
 Identities = 88/253 (34%), Positives = 142/253 (56%), Gaps = 3/253 (1%)
 Frame = +2

Query: 2   YSEAYDCKPPPFIIPLITLSQIGVFIYYAIKLNTDTDKTNDVTARSGVHLRSPLIYSPYR 181
           Y ++Y C PPP+ +  +TL ++  F+Y  + L     +          +L++ L+Y P  
Sbjct: 153 YYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQFVLQVTHPR-----YLKNSLVYHPQL 207

Query: 182 RIQAWRFIGYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSC 361
           R Q WR++ Y+F+H G  HL  N ++QL++G  LE+VH   R+G+VY+ GV+AGSLA S 
Sbjct: 208 RAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSV 267

Query: 362 FDATKYLVGASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGG 541
            D T  +VG+SGG YAL+ AH A I+ NW  M+ ++           + R+ V  +    
Sbjct: 268 ADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQF----------KLLRMAVALICMSM 317

Query: 542 DTGIAIYDRFAKEVPTPI---GFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWISLAL 712
           + G A++ RF      P     F AH GG   G  +G+ VLRN E +  ++  +WI +A+
Sbjct: 318 EFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAM 377

Query: 713 YCLFMIGAIVFNV 751
           Y +F++ A+ +N+
Sbjct: 378 YTVFVLFAVFWNI 390

>sp|P58873|RHBD4_MOUSE Rhomboid-related protein 4 (Ventrhoid transmembrane protein)
          Length = 404

 Score =  164 bits (416), Expect = 2e-40
 Identities = 88/253 (34%), Positives = 142/253 (56%), Gaps = 3/253 (1%)
 Frame = +2

Query: 2   YSEAYDCKPPPFIIPLITLSQIGVFIYYAIKLNTDTDKTNDVTARSGVHLRSPLIYSPYR 181
           Y ++Y C PPP+ +  ITL ++ +F+Y  + L+    +          +L++ L+Y P  
Sbjct: 153 YYDSYTCCPPPWFMITITLLEVALFLYNGVLLDQFVLQVTHPR-----YLKNSLVYHPQL 207

Query: 182 RIQAWRFIGYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSC 361
           R QAWR++ Y+F+H G   L  N  +QL++G  LE+VH   R+G+VY+ GV+AGSLA S 
Sbjct: 208 RAQAWRYVTYIFMHAGVEQLGLNVALQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSV 267

Query: 362 FDATKYLVGASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGG 541
            D T  +VG+SGG YAL+ AH A I+ NW  M+ ++           + R+ V  +    
Sbjct: 268 ADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQF----------KLLRMAVALICMSM 317

Query: 542 DTGIAIYDRFAKEVPTPI---GFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWISLAL 712
           + G A++ RF      P     F AH GG   G  +G+ VLRN E +  ++  +WI + +
Sbjct: 318 EFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRLQDQSLWWIFVTM 377

Query: 713 YCLFMIGAIVFNV 751
           Y +F++ A+ +N+
Sbjct: 378 YTIFVLFAVFWNI 390

>sp|Q19821|ROM1_CAEEL Rhomboid related protein 1
          Length = 356

 Score =  163 bits (412), Expect = 7e-40
 Identities = 100/266 (37%), Positives = 138/266 (51%), Gaps = 9/266 (3%)
 Frame = +2

Query: 2   YSEAYDCKPPPFIIPLITLSQIGVFIYYAIKLNTDTDKTNDV---TARSGVHLRSP---- 160
           Y ++Y   PPP  + LIT+ Q+G+F +Y      ++D    +    A   VH        
Sbjct: 101 YIDSYSWCPPPIFMLLITIIQVGIFFFY-----WESDGGRSIWTDCAGCFVHHNHTAPGI 155

Query: 161 LIYSPYRRIQAWRFIGYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLA 340
            I++P  R +AWRF  YMFLH G  HL+ N ++QL++G  LEV HK WR+G +Y+L V +
Sbjct: 156 FIFAPKLRGEAWRFTSYMFLHAGLNHLLGNVIIQLLVGIPLEVAHKIWRIGPIYLLAVTS 215

Query: 341 GSLAHSCFDATKYLVGASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIV 520
           GSL     D    LVGAS G YALI AH A +I NW  M  +W+            R++V
Sbjct: 216 GSLLQYAIDPNSLLVGASAGVYALIFAHVANVILNWHEMPLRWI------------RVLV 263

Query: 521 LFLLAGGDTGIAIYDRFAKEVPTPIGFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWI 700
           LF+    D G AI+ RF       +   AH  GA+ G   G  VL N+   + EKI  ++
Sbjct: 264 LFVFIFLDFGGAIHRRFYTNDCDSVSHLAHIAGAVTGLFFGYVVLYNVVEHRIEKIIRYV 323

Query: 701 SLALYCLFMIGAIVFNVICA--SKNL 772
            L LY  F    I+F ++    SKNL
Sbjct: 324 CLFLYSAFFATTIIFVIVRQPYSKNL 349

>sp|P20350|RHOM_DROME Rhomboid protein (Veinlet protein)
          Length = 355

 Score =  159 bits (401), Expect = 1e-38
 Identities = 93/249 (37%), Positives = 137/249 (55%), Gaps = 8/249 (3%)
 Frame = +2

Query: 32  PFIIPLITLSQIGVFIYYAIKLNTDTDKTNDVTARSGVHLRSP----LIYSPYRRIQAWR 199
           P+ I +I++ +I +F Y         D+        G+ +  P    L+Y P RR+Q WR
Sbjct: 102 PWFILVISIIEIAIFAY---------DRYTMPAQNFGLPVPIPSDSVLVYRPDRRLQVWR 152

Query: 200 FIGYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSCFDATKY 379
           F  YMFLH  + HL FN ++QL  G  LEV+H   R+G++Y+ GV AGSL  S  D+  +
Sbjct: 153 FFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVF 212

Query: 380 LVGASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGGDTGIAI 559
           LVGASGG YAL+ AH A I  N+  M+            SA  +L  + +    D G A+
Sbjct: 213 LVGASGGVYALLAAHLANITLNYAHMK------------SASTQLGSVVIFVSCDLGYAL 260

Query: 560 YDRF----AKEVPTPIGFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWISLALYCLFM 727
           Y ++    A      + + AH  GALAG  IG  VL+N   +++E++ +W++L +YC F 
Sbjct: 261 YTQYFDGSAFAKGPQVSYIAHLTGALAGLTIGFLVLKNFGHREYEQLIWWLALGVYCAFT 320

Query: 728 IGAIVFNVI 754
           + AIVFN+I
Sbjct: 321 VFAIVFNLI 329

>sp|Q8VC82|RHBD1_MOUSE Rhomboid-related protein 1 (RRP) (Rhomboid-like protein 1)
          Length = 373

 Score =  158 bits (400), Expect = 2e-38
 Identities = 88/245 (35%), Positives = 137/245 (55%), Gaps = 3/245 (1%)
 Frame = +2

Query: 26  PPPFIIPLITLSQIGVFIYYAIKLNTDTDKTNDVTARSGVHLRSPLIYSPYRRIQAWRFI 205
           PPP  +  +TL+QI VF+ Y  +LN    +T         +++SPL+Y P  R +AWRF+
Sbjct: 130 PPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPE-----YMKSPLVYHPGHRARAWRFL 184

Query: 206 GYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSCFDATKYLV 385
            YMF+H G   L FN L+QL++G  LE+VH   R+ ++Y+ GVLAGSL  S  D    +V
Sbjct: 185 TYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVV 244

Query: 386 GASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGGDTGIAIYD 565
           G SGG YAL  AH A ++ NW  M+  +           + R+++  +    + G A++ 
Sbjct: 245 GGSGGVYALCSAHLANVVMNWAGMRCPY----------KLLRMVLALVCMSSEVGRAVWL 294

Query: 566 RFAKEVPT---PIGFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWISLALYCLFMIGA 736
           RF+  +P       F AH  GA+ G  +G+ +LR+ E +  ++  +W+ L  Y  F++ A
Sbjct: 295 RFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFA 354

Query: 737 IVFNV 751
           I +NV
Sbjct: 355 IFWNV 359

>sp|O75783|RHB1_HUMAN Rhomboid-related protein 1 (RRP) (Rhomboid-like protein 1)
          Length = 438

 Score =  158 bits (400), Expect = 2e-38
 Identities = 87/245 (35%), Positives = 137/245 (55%), Gaps = 3/245 (1%)
 Frame = +2

Query: 26  PPPFIIPLITLSQIGVFIYYAIKLNTDTDKTNDVTARSGVHLRSPLIYSPYRRIQAWRFI 205
           PPP  +  +TL+QI VF+ Y  +LN    +T         +++SPL+Y P  R +AWRF+
Sbjct: 195 PPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPE-----YMKSPLVYHPGHRARAWRFL 249

Query: 206 GYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSCFDATKYLV 385
            YMF+H G   L FN L+QL++G  LE+VH   R+ ++Y+ GVLAGSL  S  D    +V
Sbjct: 250 TYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVV 309

Query: 386 GASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGGDTGIAIYD 565
           G SGG YAL  AH A ++ NW  M+  +           + R+++  +    + G A++ 
Sbjct: 310 GGSGGVYALCSAHLANVVMNWAGMRCPY----------KLLRMVLALVCMSSEVGRAVWL 359

Query: 566 RFAKEVPT---PIGFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWISLALYCLFMIGA 736
           RF+  +P       F AH  GA+ G  +G+ +LR+ E +  ++  +W+ L  Y  F++ A
Sbjct: 360 RFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFA 419

Query: 737 IVFNV 751
           + +NV
Sbjct: 420 VFWNV 424

>sp|P34356|ROM2_CAEEL Rhomboid related protein 2
          Length = 435

 Score =  144 bits (362), Expect = 4e-34
 Identities = 81/253 (32%), Positives = 127/253 (50%)
 Frame = +2

Query: 8   EAYDCKPPPFIIPLITLSQIGVFIYYAIKLNTDTDKTNDVTARSGVHLRSPLIYSPYRRI 187
           + Y C PPP  +  +++ Q+  ++YY +      D +  V     +   SPLI S Y   
Sbjct: 114 QRYKCVPPPIFLIFLSIVQLAFYLYYVV------DSSEGVWLSGPIPTMSPLIVSQYHLP 167

Query: 188 QAWRFIGYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSCFD 367
           + WR   Y  ++ G  H+IFN L+QL +G  LE+VH+ WR+ I+Y +GVL GS+     D
Sbjct: 168 ELWRLFTYCLINVGIFHIIFNILIQLAIGVPLELVHR-WRIYILYFMGVLFGSILSLALD 226

Query: 368 ATKYLVGASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGGDT 547
            T +L G + G ++LI +H  TI TN+  M+            +A  RL +L + A  D 
Sbjct: 227 PTVFLCGGAAGSFSLIASHITTIATNFKEME------------NATCRLPILIVFAALDY 274

Query: 548 GIAIYDRFAKEVPTPIGFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWISLALYCLFM 727
            +A+Y RF       +    H GG +AG L    + R  +  ++  + FW+SL L   F+
Sbjct: 275 VLAVYQRFFAPRIDKVSMYGHLGGLVAGILFTFILFRGSKPSRFYTVSFWVSLVLSGFFI 334

Query: 728 IGAIVFNVICASK 766
             AI   +I A +
Sbjct: 335 --AICITLIAAPR 345

>sp|O88779|RHBD1_RAT Rhomboid-related protein 1 (RRP) (Rhomboid-like protein 1)
          Length = 164

 Score =  107 bits (267), Expect = 5e-23
 Identities = 59/174 (33%), Positives = 94/174 (54%), Gaps = 3/174 (1%)
 Frame = +2

Query: 215 FLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSCFDATKYLVGAS 394
           F+H G   L FN L+QL++G  LE+VH   R+ ++Y+ GVLAGSL  S  D    +VG S
Sbjct: 1   FMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGS 60

Query: 395 GGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGGDTGIAIYDRFA 574
           GG YAL  AH A ++ NW  M+  +           + R+++  +    + G A++ RF+
Sbjct: 61  GGVYALCSAHLANVVMNWAGMRCPY----------KLLRMVLALVCMSSEVGRAVWLRFS 110

Query: 575 KEVPT---PIGFSAHFGGALAGFLIGIPVLRNLEVKKWEKICFWISLALYCLFM 727
             +P       F AH  GA+ G  +G+ +LR+ E +  ++  +W+ L  Y  F+
Sbjct: 111 PPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFL 164

>sp|P54493|YQGP_BACSU Hypothetical protein yqgP
          Length = 507

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 42/156 (26%), Positives = 67/156 (42%), Gaps = 4/156 (2%)
 Frame = +2

Query: 194 WRFIGYMFLHQGYIHLIFNCLMQLVLGTLLEVVHKFWRVGIVYILGVLAGSLAHSCFDAT 373
           WR +  + LH G  HL FN L    +GT +E ++   R  ++Y+   + GS+A   F   
Sbjct: 223 WRLLTPIVLHIGIAHLAFNTLALWSVGTAVERMYGSGRFLLIYLAAGITGSIASFVFSPY 282

Query: 374 KYLVGASGGCYALIGAHFATIITNWDTMQKKWLENPINFLSSAVFRLIVLFLLAGGDTGI 553
               GASG  +  +GA     ++N              FL +    +IV+ ++  G  G 
Sbjct: 283 P-SAGASGAIFGCLGALLYVALSNRKM-----------FLRTIGTNIIVIIIINLG-FGF 329

Query: 554 AIYDRFAKEVPTPIGFSAHFGGALAGFL----IGIP 649
           A+         + I  S H GG + GF     +G+P
Sbjct: 330 AV---------SNIDNSGHIGGLIGGFFAAAALGLP 356

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,917,215
Number of Sequences: 369166
Number of extensions: 2315033
Number of successful extensions: 6049
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5854
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6025
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9174518830
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_01082

  1. Dr_sW_027_C09
  2. Dr_sW_011_E06