DrC_01078
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01078 (1426 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8CIF6|SIDT2_MOUSE SID1 transmembrane family member 2 pr... 117 1e-25 sp|Q8NBJ9|SIDT2_HUMAN SID1 transmembrane family member 2 pr... 116 2e-25 sp|Q6AXF6|SIDT1_MOUSE SID1 transmembrane family member 1 pr... 111 5e-24 sp|Q9NXL6|SIDT1_HUMAN SID1 transmembrane family member 1 pr... 110 1e-23 sp|Q6Q3F5|SIDT1_RAT SID1 transmembrane family member 1 prec... 107 7e-23 sp|Q9GZC8|SID1_CAEEL Systemic RNA interference defective pr... 57 2e-07 sp|P58145|ROAA_ASTLO Ribosomal operon-associated A protein ... 39 0.048 sp|P19145|GAP1_YEAST General amino-acid permease GAP1 36 0.31 sp|P51099|NU5C_ATRJA NAD(P)H-quinone oxidoreductase chain 5... 35 0.41 sp|P51096|NU5C_ANIIN NAD(P)H-quinone oxidoreductase chain 5... 35 0.54
>sp|Q8CIF6|SIDT2_MOUSE SID1 transmembrane family member 2 precursor Length = 832 Score = 117 bits (292), Expect = 1e-25 Identities = 84/316 (26%), Positives = 146/316 (46%), Gaps = 5/316 (1%) Frame = +2 Query: 308 YGIFYALGFSLIMEGIMSASYHICPRSDTIQFDATFMYIIGCLLNLYCAIKLLQRSNNNV 487 +G+FYA+G +L+MEG++SA YH+CP QFD +FMY+I L C +KL Q+ + ++ Sbjct: 547 FGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGL----CMLKLYQKRHPDI 602 Query: 488 XXXXXXXXXXXXMSXXXXXXXXXXXXETKYKEIYKENINIFIKWLVILIFQSPIISISLL 667 + K N +I + VI I + ++S L Sbjct: 603 NASAYSAYACLAIVIFFSVLGVVFG---------KGNTAFWIVFSVIHIISTLLLSTQLY 653 Query: 668 NIFKSSALKW---SDFFICSRFVIYANIIIFVAFYLIKEFYFYFLVAIVVNFVVLLLEYY 838 + + W S F V+Y + I + L + ++ ++N+ L Y Sbjct: 654 YMGR-----WKLDSGIFRRILHVLYTDCIRQCSGPLYTDRMVLLVMGNIINWS---LAAY 705 Query: 839 FTLSENIEFWKYEILFFGFNHIFFILHNLFIK--NNCRVKFIEKFCLIWKKYKFISINLI 1012 + +F Y + N + + + +K + R+K I C++ Sbjct: 706 GLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIV------------ 753 Query: 1013 ASVIIWGLAYSAFRNAPTDWNSSASESRESNQDCIWWNYYDIHDIWHILSSIALFLSFMW 1192 + ++WG A F + W + +ESRE N+DCI +++D HDIWH LSSIA+F SF+ Sbjct: 754 CTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLV 813 Query: 1193 IFMIDEEIEKNQREPI 1240 + +D++++ QR+ I Sbjct: 814 LLTLDDDLDTVQRDKI 829
Score = 79.0 bits (193), Expect = 3e-14
Identities = 33/68 (48%), Positives = 53/68 (77%)
Frame = +3
Query: 6 VFTISVFYGLPVIQLLWHFLMVMDENGDFDKCFFNDLCSKPLGSIISFNNVASNIGYIIL 185
+ TI+VFY LPV+QL+ + V++ G+ D C++N LC+ PLG++ +FNN+ SN+GYI+L
Sbjct: 453 IATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILL 512
Query: 186 GITFILIV 209
G+ F+LI+
Sbjct: 513 GLLFLLII 520
>sp|Q8NBJ9|SIDT2_HUMAN SID1 transmembrane family member 2 precursor Length = 832 Score = 116 bits (290), Expect = 2e-25 Identities = 84/316 (26%), Positives = 146/316 (46%), Gaps = 5/316 (1%) Frame = +2 Query: 308 YGIFYALGFSLIMEGIMSASYHICPRSDTIQFDATFMYIIGCLLNLYCAIKLLQRSNNNV 487 +G+FYA+G +L+MEG++SA YH+CP QFD +FMY+I L C +KL Q+ + ++ Sbjct: 547 FGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGL----CMLKLYQKRHPDI 602 Query: 488 XXXXXXXXXXXXMSXXXXXXXXXXXXETKYKEIYKENINIFIKWLVILIFQSPIISISLL 667 + K N +I + +I I + ++S L Sbjct: 603 NASAYSAYACLAIVIFFSVLGVVFG---------KGNTAFWIVFSIIHIIATLLLSTQLY 653 Query: 668 NIFKSSALKW---SDFFICSRFVIYANIIIFVAFYLIKEFYFYFLVAIVVNFVVLLLEYY 838 + + W S F V+Y + I + L + ++ V+N+ L Y Sbjct: 654 YMGR-----WKLDSGIFRRILHVLYTDCIRQCSGPLYVDRMVLLVMGNVINWS---LAAY 705 Query: 839 FTLSENIEFWKYEILFFGFNHIFFILHNLFIK--NNCRVKFIEKFCLIWKKYKFISINLI 1012 + +F Y + N + + + +K + R+K I C++ Sbjct: 706 GLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIV------------ 753 Query: 1013 ASVIIWGLAYSAFRNAPTDWNSSASESRESNQDCIWWNYYDIHDIWHILSSIALFLSFMW 1192 + ++WG A F + W + +ESRE N+DCI +++D HDIWH LSSIA+F SF+ Sbjct: 754 CTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLV 813 Query: 1193 IFMIDEEIEKNQREPI 1240 + +D++++ QR+ I Sbjct: 814 LLTLDDDLDTVQRDKI 829
Score = 79.0 bits (193), Expect = 3e-14
Identities = 33/68 (48%), Positives = 53/68 (77%)
Frame = +3
Query: 6 VFTISVFYGLPVIQLLWHFLMVMDENGDFDKCFFNDLCSKPLGSIISFNNVASNIGYIIL 185
+ TI+VFY LPV+QL+ + V++ G+ D C++N LC+ PLG++ +FNN+ SN+GYI+L
Sbjct: 453 IATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILL 512
Query: 186 GITFILIV 209
G+ F+LI+
Sbjct: 513 GLLFLLII 520
>sp|Q6AXF6|SIDT1_MOUSE SID1 transmembrane family member 1 precursor Length = 827 Score = 111 bits (278), Expect = 5e-24 Identities = 83/325 (25%), Positives = 151/325 (46%), Gaps = 14/325 (4%) Frame = +2 Query: 308 YGIFYALGFSLIMEGIMSASYHICPRSDTIQFDATFMYIIGCLLNLYCAIKLLQRSNNNV 487 +G+FYA+G +L+MEG++SA YH+CP QFD +FMY+I L C +KL Q + ++ Sbjct: 542 FGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGL----CMLKLYQTRHPDI 597 Query: 488 XXXXXXXXXXXXMSXXXXXXXXXXXXETKYKEIYKENINIFIKWLVILIFQSPI---ISI 658 + Y + I + L ++ ++ + I Sbjct: 598 NA-------------------------SAYSAYASFAVVITLTVLGVVFGKNDVWFWIIF 632 Query: 659 SLLNIFKSSALKWSDFFICSRFVIYANIIIFVA--FYL------IKEFYFYFLVAIVV-N 811 S ++I S AL +++ RF I I A FY + Y +V ++V N Sbjct: 633 SAIHILSSLALSTQIYYM-GRFKIDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGN 691 Query: 812 FVVLLLEYYFTLSENIEFWKYEILFFGFNHIFFILHNLFIK--NNCRVKFIEKFCLIWKK 985 V ++ + +F Y + F N + ++ + +K ++ +V + FC+ Sbjct: 692 LVNWSFAFFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPLPVFCIA--- 748 Query: 986 YKFISINLIASVIIWGLAYSAFRNAPTDWNSSASESRESNQDCIWWNYYDIHDIWHILSS 1165 A+ ++W A F + W + +ESRE N++C+ +++D HDIWH LS+ Sbjct: 749 ---------ATAVVWAAALYFFFQNLSSWEGTPAESREKNRECVLLDFFDDHDIWHFLSA 799 Query: 1166 IALFLSFMWIFMIDEEIEKNQREPI 1240 ALF SF+ + +D++++ +R+ I Sbjct: 800 TALFFSFLVLLTLDDDLDVVRRDQI 824
Score = 75.1 bits (183), Expect = 5e-13
Identities = 32/68 (47%), Positives = 51/68 (75%)
Frame = +3
Query: 6 VFTISVFYGLPVIQLLWHFLMVMDENGDFDKCFFNDLCSKPLGSIISFNNVASNIGYIIL 185
+ TI+VFY LPV+QL+ + V++ G+ D C++N LC+ PLG + +FNN+ SN+G+++L
Sbjct: 448 IITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLL 507
Query: 186 GITFILIV 209
G F+LIV
Sbjct: 508 GFLFLLIV 515
>sp|Q9NXL6|SIDT1_HUMAN SID1 transmembrane family member 1 precursor Length = 827 Score = 110 bits (275), Expect = 1e-23 Identities = 82/325 (25%), Positives = 151/325 (46%), Gaps = 14/325 (4%) Frame = +2 Query: 308 YGIFYALGFSLIMEGIMSASYHICPRSDTIQFDATFMYIIGCLLNLYCAIKLLQRSNNNV 487 +G+FYA+G +L+MEG++SA YH+CP +FD +FMY+I L C +KL Q + ++ Sbjct: 542 FGLFYAMGIALMMEGVLSACYHVCPNYSNFRFDTSFMYMIAGL----CMLKLYQTRHPDI 597 Query: 488 XXXXXXXXXXXXMSXXXXXXXXXXXXETKYKEIYKENINIFIKWLVILIFQSPI---ISI 658 + Y + I + L ++ ++ + + Sbjct: 598 NA-------------------------SAYSAYASFAVVIMVTVLGVVFGKNDVWFWVIF 632 Query: 659 SLLNIFKSSALKWSDFFICSRFVIYANIIIFVA--FYL------IKEFYFYFLVAIVV-N 811 S +++ S AL +++ RF I I A FY + Y +V +VV N Sbjct: 633 SAIHVLASLALSTQIYYM-GRFKIDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLVVGN 691 Query: 812 FVVLLLEYYFTLSENIEFWKYEILFFGFNHIFFILHNLFIK--NNCRVKFIEKFCLIWKK 985 V + + +F Y + F N + ++ + +K ++ +V + FC++ Sbjct: 692 LVNWSFALFGLIYRPRDFASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPVPLFCIV--- 748 Query: 986 YKFISINLIASVIIWGLAYSAFRNAPTDWNSSASESRESNQDCIWWNYYDIHDIWHILSS 1165 A+ ++W A F + W + +ESRE N++CI +++D HDIWH LS+ Sbjct: 749 ---------ATAVMWAAALYFFFQNLSSWEGTPAESREKNRECILLDFFDDHDIWHFLSA 799 Query: 1166 IALFLSFMWIFMIDEEIEKNQREPI 1240 ALF SF+ + +D++++ +R+ I Sbjct: 800 TALFFSFLVLLTLDDDLDVVRRDQI 824
Score = 76.3 bits (186), Expect = 2e-13
Identities = 33/68 (48%), Positives = 51/68 (75%)
Frame = +3
Query: 6 VFTISVFYGLPVIQLLWHFLMVMDENGDFDKCFFNDLCSKPLGSIISFNNVASNIGYIIL 185
+ TI+VFY LPVIQL+ + V++ G+ D C++N LC+ PLG + +FNN+ SN+G+++L
Sbjct: 448 IITIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLL 507
Query: 186 GITFILIV 209
G F+LIV
Sbjct: 508 GFLFLLIV 515
>sp|Q6Q3F5|SIDT1_RAT SID1 transmembrane family member 1 precursor Length = 831 Score = 107 bits (268), Expect = 7e-23 Identities = 80/315 (25%), Positives = 142/315 (45%), Gaps = 4/315 (1%) Frame = +2 Query: 308 YGIFYALGFSLIMEGIMSASYHICPRSDTIQFDATFMYIIGCLLNLYCAIKLLQRSNNNV 487 +G+FYA+G +L+MEG++SA YH+CP QFD +FMY+I L C +KL Q + ++ Sbjct: 541 FGLFYAMGIALMMEGVLSACYHVCPNYSNFQFDTSFMYMIAGL----CMLKLYQTRHPDI 596 Query: 488 XXXXXXXXXXXXMSXXXXXXXXXXXXETKYKEIYKENINIFIKWLVILIFQSPIISISLL 667 + + I I++ L L + I + Sbjct: 597 NASAYSAYASFAVVITLTVLGVVFGKNDVWFWIIFSAIHV----LASLALSTQIYYMGRF 652 Query: 668 NIFKSSALKWSDFFICSR--FVIYANIIIFVAFYLIKEFYFYFLVAIVVNFVVLLLEYYF 841 I S +D I R V Y + I + L + +V +VN+ L + Sbjct: 653 KIDVSD----TDLGIFRRAAMVFYTDCIQQCSRPLYMDRMVLLIVGNLVNWSFALFGLIY 708 Query: 842 TLSENIEFWKYEILFFGFNHIFFILHNLFIK--NNCRVKFIEKFCLIWKKYKFISINLIA 1015 + F Y + F N + ++ + +K ++ +V + FC++ A Sbjct: 709 RPRD---FASYMLGIFICNLLLYLAFYIIMKLRSSEKVLPLPVFCIV------------A 753 Query: 1016 SVIIWGLAYSAFRNAPTDWNSSASESRESNQDCIWWNYYDIHDIWHILSSIALFLSFMWI 1195 + ++W A F + W + +ESRE N++C+ ++D HDIWH LS+ ALF SF+ + Sbjct: 754 TAVVWAAALYFFFQNLSSWEGTPAESREKNRECVLLGFFDDHDIWHFLSATALFFSFLVL 813 Query: 1196 FMIDEEIEKNQREPI 1240 +D++++ +R+ I Sbjct: 814 LTLDDDLDVVRRDQI 828
Score = 75.1 bits (183), Expect = 5e-13
Identities = 32/68 (47%), Positives = 51/68 (75%)
Frame = +3
Query: 6 VFTISVFYGLPVIQLLWHFLMVMDENGDFDKCFFNDLCSKPLGSIISFNNVASNIGYIIL 185
+ TI+VFY LPV+QL+ + V++ G+ D C++N LC+ PLG + +FNN+ SN+G+++L
Sbjct: 447 IITIAVFYALPVMQLVITYQTVVNVTGNQDICYYNFLCAHPLGVLSAFNNILSNLGHVLL 506
Query: 186 GITFILIV 209
G F+LIV
Sbjct: 507 GFLFLLIV 514
>sp|Q9GZC8|SID1_CAEEL Systemic RNA interference defective protein 1 precursor (Systemic RNAi enabling protein) Length = 776 Score = 56.6 bits (135), Expect = 2e-07 Identities = 22/75 (29%), Positives = 43/75 (57%) Frame = +2 Query: 1016 SVIIWGLAYSAFRNAPTDWNSSASESRESNQDCIWWNYYDIHDIWHILSSIALFLSFMWI 1195 S++ W +A F TDW SA+ SR N+ C+ ++ HD+WHI ++A +F+++ Sbjct: 699 SLLAWAVAGFFFFQDDTDWTRSAAASRALNKPCLLLGFFGSHDLWHIFGALAGLFTFIFV 758 Query: 1196 FMIDEEIEKNQREPI 1240 +D+++ ++ I Sbjct: 759 SFVDDDLINTRKTSI 773
Score = 44.7 bits (104), Expect = 7e-04
Identities = 16/38 (42%), Positives = 27/38 (71%)
Frame = +3
Query: 93 DKCFFNDLCSKPLGSIISFNNVASNIGYIILGITFILI 206
+ CF N C++PLG + ++NN+ +NIGY + G FI++
Sbjct: 462 EMCFHNHACARPLGELRAWNNIITNIGYTLYGAIFIVL 499
Score = 36.2 bits (82), Expect = 0.24
Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 8/84 (9%)
Frame = +2
Query: 212 NQLFCKRGKTLLSRMF*KII*KLIKNSQN--SRLYGIF------YALGFSLIMEGIMSAS 367
N + G TL +F I+ + + ++ S ++G + +G ++++ I SA+
Sbjct: 481 NNIITNIGYTLYGAIF--IVLSICRRGRHEYSHVFGTYECTLLDVTIGVFMVLQSIASAT 538
Query: 368 YHICPRSDTIQFDATFMYIIGCLL 439
YHICP QFD + +I LL
Sbjct: 539 YHICPSDVAFQFDTPCIQVICGLL 562
>sp|P58145|ROAA_ASTLO Ribosomal operon-associated A protein (RoaA) Length = 519 Score = 38.5 bits (88), Expect = 0.048 Identities = 37/134 (27%), Positives = 68/134 (50%), Gaps = 10/134 (7%) Frame = +2 Query: 659 SLLNI---FKSSALKWSDFFICSRFVIYANIIIFVAFYLIKEFYFYFLV-AIVVNFVVLL 826 SL NI FKS +++F IC ++IY + F I + FL + NF+ Sbjct: 248 SLKNIYFFFKS----YNEFNICINYLIYFLKYKGINFNFINDHVKNFLTNGLTFNFIKFF 303 Query: 827 ---LEYYFTLSE-NIEFWKYEILFFGFN-HIFFILHNLFIKNNCRVKFIEKFCL-IWKKY 988 ++ F L+E +I ++K+ I N +I I + + + NN +++K+ L + KKY Sbjct: 304 NFGYKFLFKLNEKDINYYKFNIKTLIKNFYIKNIFYTICLINNKIKNWLDKYFLFVNKKY 363 Query: 989 KFISINLIASVIIW 1030 F+ +++ S ++W Sbjct: 364 LFLELDIFISKLLW 377
>sp|P19145|GAP1_YEAST General amino-acid permease GAP1 Length = 602 Score = 35.8 bits (81), Expect = 0.31 Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 2/81 (2%) Frame = +2 Query: 587 YKENINIFIKWLVILIFQSPIISISLLNIFKSSALKWSDFFICSRFVIYANIIIF-VAFY 763 Y N N ++WLV+L + I+S S+ F + K+ D F+ ++ I +F V Y Sbjct: 169 YANNFNYMLQWLVVLPLE--IVSASITVNFWGTDPKYRDGFVALFWLAIVIINMFGVKGY 226 Query: 764 LIKEFYFYFL-VAIVVNFVVL 823 EF F F+ V VV F++L Sbjct: 227 GEAEFVFSFIKVITVVGFIIL 247
>sp|P51099|NU5C_ATRJA NAD(P)H-quinone oxidoreductase chain 5, chloroplast (NAD(P)H dehydrogenase, chain 5) (NADH-plastoquinone oxidoreductase chain 5) Length = 749 Score = 35.4 bits (80), Expect = 0.41 Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 4/97 (4%) Frame = +2 Query: 596 NINIFIKWLVILIFQSPIISISLLNIFKSSALKWSDFFICSRF-VIYANIIIFVAFYLIK 772 N++I KWL SI+LL+ ++++ W +FF + F V A+ IF+AF+L K Sbjct: 575 NLDILSKWLTP--------SINLLHKNSNNSIDWYEFFKDAVFSVSIASFGIFIAFFLYK 626 Query: 773 EFYFYFLVAIVVN-FVVLLLEYYFT--LSENIEFWKY 874 Y F ++N FV + + F+ + I W Y Sbjct: 627 PVYSSFQNLDLINSFVKMGPKRIFSDKIKNGIYDWSY 663
>sp|P51096|NU5C_ANIIN NAD(P)H-quinone oxidoreductase chain 5, chloroplast (NAD(P)H dehydrogenase, chain 5) (NADH-plastoquinone oxidoreductase chain 5) Length = 741 Score = 35.0 bits (79), Expect = 0.54 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 4/100 (4%) Frame = +2 Query: 587 YKENINIFIKWLVILIFQSPIISISLLNIFKSSALKWSDFFICSRF-VIYANIIIFVAFY 763 + ++++I KWL SI+LL+ ++++ W +F + F V A+ IF+AF+ Sbjct: 569 FNQDVDILTKWLTP--------SINLLHKNSNNSIDWYEFSKDAVFSVSIASFGIFIAFF 620 Query: 764 LIKEFYFYFLVAIVVNFVVLLLE---YYFTLSENIEFWKY 874 L K Y F ++N V + +Y + I W Y Sbjct: 621 LYKPVYSSFQNLDLINSFVKISPKRIFYDKIKNAIYDWSY 660
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148,642,414
Number of Sequences: 369166
Number of extensions: 2943786
Number of successful extensions: 7438
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6972
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7419
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 17026268400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
