Planarian EST Database

DrC_01074

Cluster detail
GO Category : Not Available
Consensus Sequence :
>DrC_01074 ATCTATATAAATCTTATATGATATAATGGCAACCTCAATAGATGAAAAATTGGTTTCGAT GTTCAAGATTTTATCTGATCACAAATTCTCGGTTATAGGAGAAATAACAAATGATATGAA ATGTACTTTATGTGGAAATATTGCTGTAAATGCACAACAAGCTCTGTGTGGGTGCAATTT TTGTAATAAATGTATTACCAATTTCATTAATAATGGGGGTAGCGCGTGTTCTGGTAATAC TGAAGAATGTAAATTAGAAAATATCTCGCAAACTGTGATAAATCATAGGTTAAATGAAGA TATTTCTAATCTCACTGTAAAATGTCCCGAAGAAAAATGTTCTTTTGAATGCCGATTGAT TGATATGGATGAACATCTTAAGGTTTGCGACAATAAAACTGAAAAATGTCCATTTTTCGG TTATGGTTGTACGCATAAAATTAAAAGTAAAAATATGAATTCTCATATGCTGCGCGAGGC TCAAGATCATAATAATATGTTAATCGATTTACTTGGGAACTTGAAAAATGAAGTTATAGA TTTACGAGAGAAAGAAAAGAATAACCACGATGAAATAGAAAAATTAAAGGAAAAGGGACG AGTTCAAGATGAAAAACTTAAAGCGATGTACGAAAATCTTCAAGCGATGAGAAGAGAAAG AGAAGAAATACGGCAAAGAATTCGAACTGGCAATCAAAATGTTTGGTATAAATCGATTTA AGTTTCAAAAGTTTTTATCATCAATCATCCTCCATATTTAAAAAAACTGTAGAATTCGTG ATGTCTTGATAAATAAATTTCGTTGTTTTTTGC

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_01074
         (813 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O00463|TRAF5_HUMAN  TNF receptor-associated factor 5 (RIN...    59   2e-08
sp|P70196|TRAF6_MOUSE  TNF receptor-associated factor 6            57   5e-08
sp|P70191|TRAF5_MOUSE  TNF receptor-associated factor 5            57   6e-08
sp|Q9Y4K3|TRAF6_HUMAN  TNF receptor-associated factor 6 (Int...    56   1e-07
sp|P68907|PZRN3_RAT  PDZ domain-containing RING finger prote...    54   5e-07
sp|Q69ZS0|PZRN3_MOUSE  PDZ domain-containing RING finger pro...    52   2e-06
sp|Q9UPQ7|PZRN3_HUMAN  PDZ domain-containing RING finger pro...    49   1e-05
sp|Q13114|TRAF3_HUMAN  TNF receptor-associated factor 3 (CD4...    47   6e-05
sp|Q60803|TRAF3_MOUSE  TNF receptor-associated factor 3 (CD4...    47   6e-05
sp|Q9BUZ4|TRAF4_HUMAN  TNF receptor-associated factor 4 (Cys...    46   1e-04

>sp|O00463|TRAF5_HUMAN TNF receptor-associated factor 5 (RING finger protein 84)
          Length = 557

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
 Frame = +2

Query: 221 SACSGNTEECKLENISQTVINHRLNEDISNLTVKCPEEK--CSFECRLI----DMDEHLK 382
           ++C    E+C        VIN + +E+  NL   CPE    C   C  I    ++DEHL 
Sbjct: 159 ASCQFRKEKCLYCKKDVVVINLQNHEE--NL---CPEYPVFCPNNCAKIILKTEVDEHLA 213

Query: 383 VCDNKTEKCPFFGYGCTHKIKSKNMNSHMLREAQDHNNMLIDLLGNLKNEVIDLREKEKN 562
           VC    + CPF  YGC    K +N+  H     ++H  ++++    L+ ++ DL +  + 
Sbjct: 214 VCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQ 273

Query: 563 NHDEIEKLKEKGRVQDEKLK 622
              +I++L E  +  +++ K
Sbjct: 274 KESKIQQLAETIKKLEKEFK 293


 Score = 40.0 bits (92), Expect = 0.008
 Identities = 34/162 (20%), Positives = 65/162 (40%), Gaps = 2/162 (1%)
 Frame = +2

Query: 83  KFSVIGEITNDMKCTLCGNIAVNAQQALCGCNFCNKCITNFIN-NGGSACSGNTEECKLE 259
           ++  +  +    KC  C ++  N  Q  CG  FC  CI +    N    C  + E  K +
Sbjct: 32  EYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICPVDKEVIKSQ 91

Query: 260 NISQTVINHRLNEDISNLTVKCPEEK-CSFECRLIDMDEHLKVCDNKTEKCPFFGYGCTH 436
            + +   ++    ++ NL V C     C+ +  L    +HL+ C  +  +C      C  
Sbjct: 92  EVFK---DNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCS--NEKCRE 146

Query: 437 KIKSKNMNSHMLREAQDHNNMLIDLLGNLKNEVIDLREKEKN 562
            +  K++  H+    Q      +    ++   VI+L+  E+N
Sbjct: 147 PVLRKDLKEHLSASCQFRKEKCLYCKKDV--VVINLQNHEEN 186

>sp|P70196|TRAF6_MOUSE TNF receptor-associated factor 6
          Length = 530

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 39/152 (25%), Positives = 64/152 (42%)
 Frame = +2

Query: 119 KCTLCGNIAVNAQQALCGCNFCNKCITNFINNGGSACSGNTEECKLENISQTVINHRLNE 298
           +C +C      A Q  CG  FC  CI   I + G  C  +  E  LEN  Q   ++    
Sbjct: 69  ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD-NEILLEN--QLFPDNFAKR 125

Query: 299 DISNLTVKCPEEKCSFECRLIDMDEHLKVCDNKTEKCPFFGYGCTHKIKSKNMNSHMLRE 478
           +I +LTVKCP + C  +  L  +++H   C+     CP     C    +   +N+H++ +
Sbjct: 126 EILSLTVKCPNKGCLQKMELRHLEDHQVHCEFALVNCP----QCQRPFQKCQVNTHIIED 181

Query: 479 AQDHNNMLIDLLGNLKNEVIDLREKEKNNHDE 574
                   +       N  + +  +EK  HD+
Sbjct: 182 CPRRQVSCV-------NCAVSMAYEEKEIHDQ 206

>sp|P70191|TRAF5_MOUSE TNF receptor-associated factor 5
          Length = 558

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 35/125 (28%), Positives = 59/125 (47%)
 Frame = +2

Query: 248 CKLENISQTVINHRLNEDISNLTVKCPEEKCSFECRLIDMDEHLKVCDNKTEKCPFFGYG 427
           CK + +   + +H  N       V CP  +C        ++EHL VC    + CPF  YG
Sbjct: 171 CKRDIVVTNLQDHEENS-CPAYPVSCPN-RCVQTIPRARVNEHLTVCPEAEQDCPFKHYG 228

Query: 428 CTHKIKSKNMNSHMLREAQDHNNMLIDLLGNLKNEVIDLREKEKNNHDEIEKLKEKGRVQ 607
           CT K K  N+  H     QDH  ++++    L+  + DL +  +    +I++L E  +  
Sbjct: 229 CTVKGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQLAETVKKF 288

Query: 608 DEKLK 622
           +++LK
Sbjct: 289 EKELK 293


 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 30/133 (22%), Positives = 55/133 (41%), Gaps = 2/133 (1%)
 Frame = +2

Query: 77  DHKFSVIGEITNDMKCTLCGNIAVNAQQALCGCNFCNKCITNFIN-NGGSACSGNTEECK 253
           D ++  + ++    KC  C ++  N  Q  CG  FC +CI +    N    C  + E  K
Sbjct: 30  DTEYQFVEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICPVDKEVIK 89

Query: 254 LENISQTVINHRLNEDISNLTVKCPEEK-CSFECRLIDMDEHLKVCDNKTEKCPFFGYGC 430
            + + +   ++    ++ NL V C     C+    L    +HL+ C  +   CP     C
Sbjct: 90  PQEVFK---DNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCP--NESC 144

Query: 431 THKIKSKNMNSHM 469
              +  K++  H+
Sbjct: 145 REAMLRKDVKEHL 157

>sp|Q9Y4K3|TRAF6_HUMAN TNF receptor-associated factor 6 (Interleukin 1 signal transducer)
           (RING finger protein 85)
          Length = 522

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 35/120 (29%), Positives = 54/120 (45%)
 Frame = +2

Query: 119 KCTLCGNIAVNAQQALCGCNFCNKCITNFINNGGSACSGNTEECKLENISQTVINHRLNE 298
           +C +C      A Q  CG  FC  CI   I + G  C  +  E  LEN  Q   ++    
Sbjct: 69  ECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD-NEILLEN--QLFPDNFAKR 125

Query: 299 DISNLTVKCPEEKCSFECRLIDMDEHLKVCDNKTEKCPFFGYGCTHKIKSKNMNSHMLRE 478
           +I +L VKCP E C  +  L  +++H   C+     CP     C    +  ++N H+L++
Sbjct: 126 EILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCP----QCQRPFQKFHINIHILKD 181

>sp|P68907|PZRN3_RAT PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic
           domain-associated protein 3) (SEMACAP3 protein)
          Length = 1062

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 4/134 (2%)
 Frame = +2

Query: 98  GEITNDMKCTLCGNIAVNAQQALCGCNFCNKCITNFINNGGSACSGNTEECKLENISQTV 277
           GE+  D+KC LC  +  +     CG  FC  C+  ++   GS  S     C+   +S   
Sbjct: 10  GEVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPS----RCR-GRLSAKE 64

Query: 278 INH--RLNEDISNLTVKCPE--EKCSFECRLIDMDEHLKVCDNKTEKCPFFGYGCTHKIK 445
           +NH   L   I  L +KC      C    +L D+ EHL+ CD    +C     GC   + 
Sbjct: 65  LNHVLPLKRLILKLDIKCAHAARGCGRVVKLQDLPEHLERCDFAPARCRH--AGCGQLLL 122

Query: 446 SKNMNSHMLREAQD 487
            +++ +HM R+A D
Sbjct: 123 RRDVEAHM-RDACD 135

>sp|Q69ZS0|PZRN3_MOUSE PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic
           domain-associated protein 3) (SEMACAP3 protein)
          Length = 1063

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 7/137 (5%)
 Frame = +2

Query: 98  GEITNDMKCTLCGNIAVNAQQALCGCNFCNKCITNFINNGGSA---CSGNTEECKLENIS 268
           G++  D+KC LC  +  +     CG  FC  C+  ++   GS    C G         +S
Sbjct: 10  GDVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRG--------RLS 61

Query: 269 QTVINH--RLNEDISNLTVKCPE--EKCSFECRLIDMDEHLKVCDNKTEKCPFFGYGCTH 436
              +NH   L   I  L +KC      C    +L D+ EHL+ CD    +C     GC  
Sbjct: 62  AKELNHVLPLKRLILKLDIKCAHAARGCGRVVKLQDLPEHLERCDFAPARCRH--AGCGQ 119

Query: 437 KIKSKNMNSHMLREAQD 487
            +  +++ +HM R+A D
Sbjct: 120 LLLRRDVEAHM-RDACD 135

>sp|Q9UPQ7|PZRN3_HUMAN PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein
           X 3) (Semaphorin cytoplasmic domain-associated protein
           3) (SEMACAP3 protein)
          Length = 1066

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 38/137 (27%), Positives = 59/137 (43%), Gaps = 7/137 (5%)
 Frame = +2

Query: 98  GEITNDMKCTLCGNIAVNAQQALCGCNFCNKCITNFINNGGSA---CSGNTEECKLENIS 268
           G++  D+KC LC  +  +     CG  FC  C+  ++   GS    C G         +S
Sbjct: 10  GDVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRG--------RLS 61

Query: 269 QTVINH--RLNEDISNLTVKC--PEEKCSFECRLIDMDEHLKVCDNKTEKCPFFGYGCTH 436
              +NH   L   I  L +KC      C    +L  + EHL+ CD    +C     GC  
Sbjct: 62  AKELNHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLERCDFAPARCRH--AGCGQ 119

Query: 437 KIKSKNMNSHMLREAQD 487
            +  +++ +HM R+A D
Sbjct: 120 VLLRRDVEAHM-RDACD 135

>sp|Q13114|TRAF3_HUMAN TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (CD40 binding protein) (CD40BP) (LMP1
           associated protein) (LAP1) (CAP-1)
          Length = 568

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 4/134 (2%)
 Frame = +2

Query: 248 CKLENISQTVINHRLNEDISNLTVKCPEEKCSFECRL-IDMDEHLKVCDNKTEKCPFFGY 424
           CK + +    +    + D   + V CP  KCS +  L  ++  HL  C N    C F  Y
Sbjct: 180 CKSQ-VPMIALQKHEDTDCPCVVVSCPH-KCSVQTLLRSELSAHLSECVNAPSTCSFKRY 237

Query: 425 GCTHKIKSKNMNSHMLREAQDHNNMLIDLLGNLKNEVIDLREKEKNNHDEIEKLKEK--- 595
           GC  +  ++ + +H    A  H N+L +   +L+ +V  L+ +    +  I+ L  +   
Sbjct: 238 GCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICS 297

Query: 596 GRVQDEKLKAMYEN 637
             ++ E+ K M  N
Sbjct: 298 FEIEIERQKEMLRN 311


 Score = 41.6 bits (96), Expect = 0.003
 Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 2/132 (1%)
 Frame = +2

Query: 80  HKFSVIGEITNDMKCTLCGNIAVNAQQALCGCNFCNKCITNFINNGGSACSGNTEECKLE 259
           +K   +  + +  KC  C  +  + +Q  CG  FC  C+   +++    C+   E    +
Sbjct: 39  YKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKD 98

Query: 260 NISQTVINHRLNEDISNLTVKCPEEK--CSFECRLIDMDEHLKVCDNKTEKCPFFGYGCT 433
            + +   ++    +I  L + C  E   C+ +  L  +  HLK  D   E+ P     C 
Sbjct: 99  KVFK---DNCCKREILALQIYCRNESRGCAEQLTLGHLLVHLK-NDCHFEELPCVRPDCK 154

Query: 434 HKIKSKNMNSHM 469
            K+  K++  H+
Sbjct: 155 EKVLRKDLRDHV 166

>sp|Q60803|TRAF3_MOUSE TNF receptor-associated factor 3 (CD40 receptor associated factor
           1) (CRAF1) (TRAFAMN)
          Length = 567

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 36/143 (25%), Positives = 59/143 (41%), Gaps = 4/143 (2%)
 Frame = +2

Query: 221 SACSGNTEECKLENISQTVINHRLNEDISNLTVKCPEEKCSFECRL-IDMDEHLKVCDNK 397
           S C       KL+    T        D   + V CP  KCS +  L  ++  HL  C N 
Sbjct: 177 SHCKSQVPMIKLQKHEDT--------DCPCVVVSCPH-KCSVQTLLRSELSAHLSECVNA 227

Query: 398 TEKCPFFGYGCTHKIKSKNMNSHMLREAQDHNNMLIDLLGNLKNEVIDLREKEKNNHDEI 577
              C F  YGC  +  ++ + +H    A  H N+L +   +L+ +V  L+ +    +  I
Sbjct: 228 PSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSI 287

Query: 578 EKLKEK---GRVQDEKLKAMYEN 637
           + L  +     ++ E+ K M  N
Sbjct: 288 QSLHNQICSFEIEIERQKEMLRN 310


 Score = 42.7 bits (99), Expect = 0.001
 Identities = 29/132 (21%), Positives = 56/132 (42%), Gaps = 2/132 (1%)
 Frame = +2

Query: 80  HKFSVIGEITNDMKCTLCGNIAVNAQQALCGCNFCNKCITNFINNGGSACSGNTEECKLE 259
           +K   +  + +  KC  C  +  N +Q  CG  FC  C+   +++    C+   E    +
Sbjct: 38  YKEKFVKTVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKD 97

Query: 260 NISQTVINHRLNEDISNLTVKCPEE--KCSFECRLIDMDEHLKVCDNKTEKCPFFGYGCT 433
            + +   ++    +I  L V C  E   C+ +  L  +  HLK  + + E+ P     C 
Sbjct: 98  KVFK---DNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLK-NECQFEELPCLRADCK 153

Query: 434 HKIKSKNMNSHM 469
            K+  K++  H+
Sbjct: 154 EKVLRKDLRDHV 165

>sp|Q9BUZ4|TRAF4_HUMAN TNF receptor-associated factor 4 (Cysteine-rich domain associated
           with RING and Traf domains protein 1) (Malignant 62)
           (RING finger protein 83)
          Length = 470

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 40/162 (24%), Positives = 64/162 (39%), Gaps = 16/162 (9%)
 Frame = +2

Query: 116 MKCTLCG----NIAVNAQQALCGCN--FC-NKCITNFIN-----NGGSACSGNTEECKL- 256
           +KC  CG      A  + + +C     +C NKC    +      +  S C   T+ C   
Sbjct: 139 LKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYC 198

Query: 257 --ENISQTVINHRLNEDISNLTVKCPEEKCSFECRLIDMDEHLK-VCDNKTEKCPFFGYG 427
             E +  T+ +H+       L V CP +         D+  HLK  C+     CPF   G
Sbjct: 199 TKEFVFDTIQSHQYQ--CPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSG 256

Query: 428 CTHKIKSKNMNSHMLREAQDHNNMLIDLLGNLKNEVIDLREK 553
           C H+     M  H+    + H  M+  L+   + E+ +LR +
Sbjct: 257 CKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRE 298


 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 3/134 (2%)
 Frame = +2

Query: 77  DHKFSVIGEITNDMKCTLCGN-IAVNAQQALCGCNFCNKCITNFINNGGSACSGNTEECK 253
           D+KF  + +    + C LCG  +    Q + CG  FC+ C+  F++ G   C    E+  
Sbjct: 5   DYKF--LEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKC---PEDQL 59

Query: 254 LENISQTVINHRLNEDISNLTVKC--PEEKCSFECRLIDMDEHLKVCDNKTEKCPFFGYG 427
             + ++   +  L   +  L ++C   EE C +   L  +  HL  C      CP     
Sbjct: 60  PLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCP---NR 116

Query: 428 CTHKIKSKNMNSHM 469
           C  K+  +++ +H+
Sbjct: 117 CPMKLSRRDLPAHL 130

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,085,501
Number of Sequences: 369166
Number of extensions: 1582913
Number of successful extensions: 5746
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5287
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5702
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7763237265
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_01074

Planaria EST Database

DrC_01074

BLASTX 2.2.13 [Nov-27-2005]

Cluster detail