Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01060 (994 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P07602|SAP_HUMAN Proactivator polypeptide precursor [Con... 45 2e-04 sp|P26779|SAP_BOVIN Proactivator polypeptide precursor [Con... 43 0.002 sp|Q8XNE2|NADB_CLOPE L-aspartate oxidase (LASPO) (Quinolina... 35 0.43 sp|P30337|CHIN_RAT N-chimaerin (NC) (N-chimerin) (Alpha chi... 32 2.1 sp|Q6RZJ4|V27K_RABPU 27 kDa virion core protein 32 2.1 sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 precursor (Tyr... 32 2.1 sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 precursor (T... 32 2.8 sp|Q6L0Y7|TRUA_PICTO tRNA pseudouridine synthase A (tRNA-ur... 32 3.6 sp|Q91V57|CHIN_MOUSE N-chimaerin (NC) (N-chimerin) (Alpha c... 31 4.8 sp|P69037|VFP_NPVAC FP protein (25 kDa protein) >gi|6880566... 31 4.8
>sp|P07602|SAP_HUMAN Proactivator polypeptide precursor [Contains: Saposin A (Protein A); Saposin B-Val; Saposin B (Sphingolipid activator protein 1) (SAP-1) (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin C (Co-beta-glucosidase) (A1 activator) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin D (Protein C) (Component C)] Length = 524 Score = 45.4 bits (106), Expect = 2e-04 Identities = 39/175 (22%), Positives = 74/175 (42%) Frame = +3 Query: 333 SEKFCNRCENIPESKFLKWAKSVDIKMLTDAGYKVMCSELNTTESERCREIISHIGTVIL 512 S+ +C CE + + + K + DA + MCS+L + SE C+E++ G+ IL Sbjct: 311 SDVYCEVCEFLVKEVTKLIDNNKTEKEILDA-FDKMCSKLPKSLSEECQEVVDTYGSSIL 369 Query: 513 HELENVLSVKNVCYKIYRCPMNLETTNEMHSFYYDTFDFTRQTSKRCEVCKAFSDVFSSG 692 L +S + VC ++ C +H F CEVCK Sbjct: 370 SILLEEVSPELVCSMLHLCSGTRLPALTVHVTQPKDGGF-------CEVCKKLVGYLDRN 422 Query: 693 IDRDLFEEMVVDQFEKVYCNKLFPKKEHMCKKFLKNELPNILNKLRVSIHRDYLC 857 ++++ ++ ++ EK C+ L + C +F+ P ++ L + ++C Sbjct: 423 LEKNSTKQEILAALEK-GCSFLPDPYQKQCDQFVAEYEPVLIEILVEVMDPSFVC 476
>sp|P26779|SAP_BOVIN Proactivator polypeptide precursor [Contains: Saposin A (Protein A); Saposin B (Sphingolipid activator protein 1) (SAP-1) (Cerebroside sulfate activator) (CSAct) (Dispersin) (Sulfatide/GM1 activator); Saposin C (Co-beta-glucosidase) (A1 activator) (Glucosylceramidase activator) (Sphingolipid activator protein 2) (SAP-2); Saposin D (Protein C) (Component C)] Length = 525 Score = 42.7 bits (99), Expect = 0.002 Identities = 33/143 (23%), Positives = 63/143 (44%), Gaps = 3/143 (2%) Frame = +3 Query: 438 MCSELNTTESERCREIISHIGTVILHELENVLSVKNVCYKIYRCP---MNLETTNEMHSF 608 +CS+L T+ +E+C+E++ G IL L + S + VC ++ C + T M Sbjct: 346 VCSKLPTSLAEQCQEVVDTYGRSILSILLDEASPELVCSMLHLCSSRGLPAATVRVM--- 402 Query: 609 YYDTFDFTRQTSKRCEVCKAFSDVFSSGIDRDLFEEMVVDQFEKVYCNKLFPKKEHMCKK 788 R+ CEVCK ++++ +E ++ EK C+ L + C + Sbjct: 403 -------PRKDGGFCEVCKKLVGYLDRNLEKNSTKEQILAALEK-GCSFLPDQYRKQCDQ 454 Query: 789 FLKNELPNILNKLRVSIHRDYLC 857 F+ P ++ L + ++C Sbjct: 455 FVTEYEPVLIEILVEVMDPSFVC 477
>sp|Q8XNE2|NADB_CLOPE L-aspartate oxidase (LASPO) (Quinolinate synthetase B) Length = 439 Score = 34.7 bits (78), Expect = 0.43 Identities = 15/44 (34%), Positives = 24/44 (54%) Frame = +3 Query: 693 IDRDLFEEMVVDQFEKVYCNKLFPKKEHMCKKFLKNELPNILNK 824 + RD+ + + ++ +K N +F M K FL+N PNI NK Sbjct: 265 LPRDIVSKKIYEEMKKTNSNNVFLDVSFMEKSFLQNRFPNIYNK 308
>sp|P30337|CHIN_RAT N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho-GTPase-activating protein 2) Length = 334 Score = 32.3 bits (72), Expect = 2.1 Identities = 19/58 (32%), Positives = 33/58 (56%) Frame = +3 Query: 375 KFLKWAKSVDIKMLTDAGYKVMCSELNTTESERCREIISHIGTVILHELENVLSVKNV 548 KF++ AK VD + ++ + S L E R +++H+ V LHE EN++S +N+ Sbjct: 237 KFIESAKIVDPDEQLETLHEALRS-LPPAHCETLRYLMAHLKRVTLHEKENLMSAENL 293
>sp|Q6RZJ4|V27K_RABPU 27 kDa virion core protein Length = 237 Score = 32.3 bits (72), Expect = 2.1 Identities = 30/124 (24%), Positives = 53/124 (42%), Gaps = 6/124 (4%) Frame = +3 Query: 261 NHNNFYDYFFTD-EYHDFFERDQKPSEKFCNRCENIPESKFLKWAKSVDIKMLTDAGYKV 437 NHN+F T + H FF +K+ + C + S F + ++++ DAG +V Sbjct: 27 NHNDFIRSKLTKLKEHVFFSEYIVTPDKYGSLCVELNGSSFQHGGRYIEVEEFIDAGRQV 86 Query: 438 -MCSELNTTESERCREIISHIGTVILHELENVLSVKNVCYKIYRCPMNL----ETTNEMH 602 CS N + +I H +++++ + KN + P +L TN + Sbjct: 87 RWCSTSNHISEDIPEDI--HTDKFVIYDIYTFDAFKNKRLVFVQVPPSLGDDSYLTNPLL 144 Query: 603 SFYY 614 S YY Sbjct: 145 SPYY 148
>sp|P54757|EPHA5_RAT Ephrin type-A receptor 5 precursor (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) Length = 1005 Score = 32.3 bits (72), Expect = 2.1 Identities = 19/73 (26%), Positives = 29/73 (39%), Gaps = 9/73 (12%) Frame = +3 Query: 306 DFFERDQKPSEKFCNRCENIPE---------SKFLKWAKSVDIKMLTDAGYKVMCSELNT 458 D+F R+ P C R + P S FL+W D D Y ++C + N Sbjct: 343 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGGKDVSYYILCKKCN- 401 Query: 459 TESERCREIISHI 497 + + C E H+ Sbjct: 402 SHAGVCEECGGHV 414
>sp|P54756|EPHA5_HUMAN Ephrin type-A receptor 5 precursor (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein-tyrosine kinase HEK7) Length = 1037 Score = 32.0 bits (71), Expect = 2.8 Identities = 19/73 (26%), Positives = 28/73 (38%), Gaps = 9/73 (12%) Frame = +3 Query: 306 DFFERDQKPSEKFCNRCENIPE---------SKFLKWAKSVDIKMLTDAGYKVMCSELNT 458 D+F R+ P C R + P S FL+W D D Y + C + N Sbjct: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCN- 399 Query: 459 TESERCREIISHI 497 + + C E H+ Sbjct: 400 SHAGVCEECGGHV 412
>sp|Q6L0Y7|TRUA_PICTO tRNA pseudouridine synthase A (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I) Length = 251 Score = 31.6 bits (70), Expect = 3.6 Identities = 10/26 (38%), Positives = 15/26 (57%) Frame = +3 Query: 207 HQFFHEYFFNNQYTSPTFNHNNFYDY 284 + FFH Y+ +N Y +P +N Y Y Sbjct: 87 NMFFHSYYLSNSYINPRYNSMKIYKY 112
>sp|Q91V57|CHIN_MOUSE N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho-GTPase-activating protein 2) Length = 334 Score = 31.2 bits (69), Expect = 4.8 Identities = 18/58 (31%), Positives = 33/58 (56%) Frame = +3 Query: 375 KFLKWAKSVDIKMLTDAGYKVMCSELNTTESERCREIISHIGTVILHELENVLSVKNV 548 KF++ AK +D + ++ + S L E R +++H+ V LHE EN++S +N+ Sbjct: 237 KFIESAKIMDPDEQLETLHEALRS-LPPAHCETLRYLMAHLKRVTLHEKENLMSAENL 293
>sp|P69037|VFP_NPVAC FP protein (25 kDa protein) sp|P69038|VFP_NPVGM FP protein (25 kDa protein) Length = 214 Score = 31.2 bits (69), Expect = 4.8 Identities = 13/46 (28%), Positives = 26/46 (56%) Frame = +1 Query: 88 MNIQHIIINIFMKHHIPKIICFHTNISNISTKIKQQIISHINFSMN 225 +N +H+I + F K+HI +C T TK +++ + + N ++N Sbjct: 77 LNFKHVIESSFDKNHIVAKLCDATRAKEWQTKSRERRLKNFNLNIN 122
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 109,883,005 Number of Sequences: 369166 Number of extensions: 2371267 Number of successful extensions: 7097 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6649 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7076 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10479017505 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)