Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01051 (739 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O75494|FUSIP_HUMAN FUS-interacting serine-arginine-rich ... 49 1e-05 sp|Q8WXF0|SRR35_HUMAN 35 kDa SR repressor protein (SRrp35) 47 4e-05 sp|Q9NEW6|RSP3_CAEEL Probable splicing factor, arginine/ser... 38 0.025 sp|P84103|SFRS3_HUMAN Splicing factor, arginine/serine-rich... 37 0.072 sp|Q02427|RBP1_DROME RNA-binding protein 1 35 0.16 sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (E... 35 0.16 sp|P30352|SFRS2_CHICK Splicing factor, arginine/serine-rich... 34 0.46 sp|Q6PDU1|SFRS2_RAT Splicing factor, arginine/serine-rich 2... 34 0.46 sp|Q5R1W5|SFRS2_PANTR Splicing factor, arginine/serine-rich... 34 0.46 sp|Q18409|RSP6_CAEEL Probable splicing factor, arginine/ser... 33 0.79
>sp|O75494|FUSIP_HUMAN FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (40 kDa SR-repressor protein) (SRrp40) (Splicing factor SRp38) sp|Q9R0U0|FUSIP_MOUSE FUS-interacting serine-arginine-rich protein 1 (TLS-associated protein with Ser-Arg repeats) (TLS-associated protein with SR repeats) (TASR) (TLS-associated serine-arginine protein) (TLS-associated SR protein) (Neural-specific SR protein) (Neural-salient serine/arginine-rich protein) Length = 262 Score = 48.9 bits (115), Expect = 1e-05 Identities = 23/46 (50%), Positives = 30/46 (65%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNGYKKTPAEMRDKEKTN 511 FED RDAEDA LD + GR+I ++F G +KTP +M+ KE N Sbjct: 58 FEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRN 103
>sp|Q8WXF0|SRR35_HUMAN 35 kDa SR repressor protein (SRrp35) Length = 261 Score = 47.4 bits (111), Expect = 4e-05 Identities = 21/44 (47%), Positives = 30/44 (68%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNGYKKTPAEMRDKEK 505 FED RDAEDA L+ + GR+I ++F G +KTP +M+ KE+ Sbjct: 58 FEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKER 101
>sp|Q9NEW6|RSP3_CAEEL Probable splicing factor, arginine/serine-rich 3 (CeSF2) (CeSF2/ASF) Length = 258 Score = 38.1 bits (87), Expect = 0.025 Identities = 19/31 (61%), Positives = 20/31 (64%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNG 466 FED RDAEDA DG + GR I VEFT G Sbjct: 53 FEDHRDAEDAVRARDGYEFDGRRIRVEFTRG 83
>sp|P84103|SFRS3_HUMAN Splicing factor, arginine/serine-rich 3 (Pre-mRNA splicing factor SRP20) sp|P84104|SFRS3_MOUSE Splicing factor, arginine/serine-rich 3 (Pre-mRNA splicing factor SRP20) (X16 protein) Length = 164 Score = 36.6 bits (83), Expect = 0.072 Identities = 18/35 (51%), Positives = 22/35 (62%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNGYKKT 478 FED RDA DA LDG L G + VE +NG K++ Sbjct: 53 FEDPRDAADAVRELDGRTLCGCRVRVELSNGEKRS 87
>sp|Q02427|RBP1_DROME RNA-binding protein 1 Length = 144 Score = 35.4 bits (80), Expect = 0.16 Identities = 17/31 (54%), Positives = 20/31 (64%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNG 466 FED RDAEDA LDG + G I VE ++G Sbjct: 54 FEDRRDAEDATRALDGTRCCGTRIRVEMSSG 84
>sp|P26686|SRR55_DROME Serine-arginine protein 55 (SRP55) (Enhancer of deformed) (52-kDa bracketing protein) (B52 protein) Length = 376 Score = 35.4 bits (80), Expect = 0.16 Identities = 16/31 (51%), Positives = 21/31 (67%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNG 466 FED+RDA+DA L+G +LLG + VE G Sbjct: 44 FEDYRDADDAVYELNGKELLGERVVVEPARG 74
>sp|P30352|SFRS2_CHICK Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (PR264 protein) Length = 221 Score = 33.9 bits (76), Expect = 0.46 Identities = 18/36 (50%), Positives = 22/36 (61%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNGYKKTP 481 F D RDAEDA +DGA L GRE+ V+ Y + P Sbjct: 62 FHDKRDAEDAMDAMDGAVLDGRELRVQMAR-YGRPP 96
>sp|Q6PDU1|SFRS2_RAT Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) sp|Q62093|SFRS2_MOUSE Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (PR264 protein) sp|Q01130|SFRS2_HUMAN Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) (PR264 protein) Length = 221 Score = 33.9 bits (76), Expect = 0.46 Identities = 18/36 (50%), Positives = 22/36 (61%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNGYKKTP 481 F D RDAEDA +DGA L GRE+ V+ Y + P Sbjct: 62 FHDKRDAEDAMDAMDGAVLDGRELRVQMAR-YGRPP 96
>sp|Q5R1W5|SFRS2_PANTR Splicing factor, arginine/serine-rich 2 (Splicing factor SC35) (SC-35) (Splicing component, 35 kDa) Length = 221 Score = 33.9 bits (76), Expect = 0.46 Identities = 18/36 (50%), Positives = 22/36 (61%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNGYKKTP 481 F D RDAEDA +DGA L GRE+ V+ Y + P Sbjct: 62 FHDKRDAEDAMDAMDGAVLDGRELRVQMAR-YGRPP 96
>sp|Q18409|RSP6_CAEEL Probable splicing factor, arginine/serine-rich 6 (RNA-binding protein srp-1) (CeSRp20) Length = 179 Score = 33.1 bits (74), Expect = 0.79 Identities = 14/34 (41%), Positives = 22/34 (64%) Frame = +2 Query: 374 FEDFRDAEDAKSRLDGAQLLGREIGVEFTNGYKK 475 ++D RDAEDA LDG+++ G VE + G ++ Sbjct: 46 YDDVRDAEDAVRALDGSRICGVRARVELSTGQRR 79
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 66,555,795 Number of Sequences: 369166 Number of extensions: 1142831 Number of successful extensions: 2366 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2335 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2366 length of database: 68,354,980 effective HSP length: 108 effective length of database: 48,403,600 effective search space used: 6631293200 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)