Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01004 (327 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 137 1e-32 sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 135 2e-32 sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 134 8e-32 sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 134 8e-32 sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 132 2e-31 sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 131 5e-31 sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 129 2e-30 sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 129 2e-30 sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 129 2e-30 sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 128 4e-30
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 339 Score = 137 bits (344), Expect = 1e-32 Identities = 62/87 (71%), Positives = 71/87 (81%), Gaps = 1/87 (1%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGT-EDGNNYWLVKNSWGTVW 178 P+SVAIDAS+ SFQLY G+YNEP+C LDHGVLVVGYGT E G +YWLVKNSWGT W Sbjct: 253 PVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVKNSWGTTW 312 Query: 179 GINGYIKMSKDANNQCGIATKASYPLV 259 G GYIKM+++ NNQCGIAT +SYP V Sbjct: 313 GEQGYIKMARNQNNQCGIATASSYPTV 339
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 135 bits (341), Expect = 2e-32 Identities = 63/89 (70%), Positives = 70/89 (78%), Gaps = 3/89 (3%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYG---TEDGNNYWLVKNSWGT 172 PISVAIDA + SFQ YKSGIY +PDCSS LDHGVLVVGYG T+ N +W+VKNSWG Sbjct: 245 PISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGP 304 Query: 173 VWGINGYIKMSKDANNQCGIATKASYPLV 259 WG NGY+KM+KD NN CGIAT ASYP V Sbjct: 305 EWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U) Length = 334 Score = 134 bits (336), Expect = 8e-32 Identities = 64/90 (71%), Positives = 70/90 (77%), Gaps = 4/90 (4%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGNN----YWLVKNSWG 169 PISVA+DA + SFQ YKSGIY EPDCSS LDHGVLVVGYG E N+ YWLVKNSWG Sbjct: 245 PISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWG 304 Query: 170 TVWGINGYIKMSKDANNQCGIATKASYPLV 259 WG NGY+K++KD NN CGIAT ASYP V Sbjct: 305 PEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 217 Score = 134 bits (336), Expect = 8e-32 Identities = 63/87 (72%), Positives = 69/87 (79%), Gaps = 1/87 (1%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGNN-YWLVKNSWGTVW 178 PISVAIDA + SFQ YKSGIY +PDCSS LDHGVLVVGYG E NN +W+VKNSWG W Sbjct: 131 PISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTNNKFWIVKNSWGPEW 190 Query: 179 GINGYIKMSKDANNQCGIATKASYPLV 259 G GY+KM+KD NN CGIAT ASYP V Sbjct: 191 GNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 132 bits (332), Expect = 2e-31 Identities = 62/90 (68%), Positives = 69/90 (76%), Gaps = 4/90 (4%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTE----DGNNYWLVKNSWG 169 PISVAIDA + SFQ YKSGIY +PDCS LDHGVLVVGYG E + N +W+VKNSWG Sbjct: 245 PISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKNSWG 304 Query: 170 TVWGINGYIKMSKDANNQCGIATKASYPLV 259 WG NGY+KM+KD NN CGIAT ASYP V Sbjct: 305 PEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 131 bits (329), Expect = 5e-31 Identities = 61/90 (67%), Positives = 70/90 (77%), Gaps = 4/90 (4%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTE----DGNNYWLVKNSWG 169 PISVAIDA + SFQ YKSGIY +PDCSS LDHGVLVVGYG E + + +W+VKNSWG Sbjct: 245 PISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWG 304 Query: 170 TVWGINGYIKMSKDANNQCGIATKASYPLV 259 WG NGY+KM+KD NN CGI+T ASYP V Sbjct: 305 PEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 129 bits (325), Expect = 2e-30 Identities = 61/90 (67%), Positives = 67/90 (74%), Gaps = 4/90 (4%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTE----DGNNYWLVKNSWG 169 PISVAIDA + SF YK GIY EPDCSS +DHGVLVVGYG E D N YWLVKNSWG Sbjct: 244 PISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWG 303 Query: 170 TVWGINGYIKMSKDANNQCGIATKASYPLV 259 WG+ GY+KM+KD N CGIA+ ASYP V Sbjct: 304 EEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 341 Score = 129 bits (325), Expect = 2e-30 Identities = 58/87 (66%), Positives = 69/87 (79%), Gaps = 1/87 (1%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGT-EDGNNYWLVKNSWGTVW 178 P+SVAIDAS+ SFQ Y G+YNEP C + LDHGVLVVG+GT E G +YWLVKNSWGT W Sbjct: 255 PVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTW 314 Query: 179 GINGYIKMSKDANNQCGIATKASYPLV 259 G G+IKM ++ NQCGIA+ +SYPLV Sbjct: 315 GDKGFIKMLRNKENQCGIASASSYPLV 341
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor Length = 322 Score = 129 bits (324), Expect = 2e-30 Identities = 58/86 (67%), Positives = 69/86 (80%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGNNYWLVKNSWGTVWG 181 PISVAIDAS+ SFQ Y +G+Y EP CSS+QLDH VL VGYG+E G ++WLVKNSW T WG Sbjct: 237 PISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGSEGGQDFWLVKNSWATSWG 296 Query: 182 INGYIKMSKDANNQCGIATKASYPLV 259 +GYIKM+++ NN CGIAT A YP V Sbjct: 297 ESGYIKMARNRNNNCGIATDACYPTV 322
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor Length = 323 Score = 128 bits (322), Expect = 4e-30 Identities = 58/86 (67%), Positives = 67/86 (77%) Frame = +2 Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGNNYWLVKNSWGTVWG 181 PISV IDA++ SFQ Y SG+Y EP CS + LDH VL VGYG+E G ++WLVKNSW T WG Sbjct: 238 PISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWG 297 Query: 182 INGYIKMSKDANNQCGIATKASYPLV 259 GYIKMS++ NN CGIAT ASYPLV Sbjct: 298 DAGYIKMSRNRNNNCGIATVASYPLV 323
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,859,743 Number of Sequences: 369166 Number of extensions: 798069 Number of successful extensions: 2336 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2135 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2194 length of database: 68,354,980 effective HSP length: 77 effective length of database: 54,130,385 effective search space used: 1678041935 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)