Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_015_L12 (279 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 112 3e-25 sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 110 1e-24 sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 109 2e-24 sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 109 2e-24 sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 109 2e-24 sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 108 5e-24 sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 107 7e-24 sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 107 9e-24 sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 106 1e-23 sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 106 2e-23
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 339 Score = 112 bits (280), Expect = 3e-25 Identities = 49/69 (71%), Positives = 56/69 (81%), Gaps = 1/69 (1%) Frame = -2 Query: 272 GIYNEPDCSSTQLDHGVLVVGYGT-EDGSNYWLVKNSWGTVWGIDGYIKMSKDANNQCGI 96 G+YNEP+C LDHGVLVVGYGT E G +YWLVKNSWGT WG GYIKM+++ NNQCGI Sbjct: 271 GVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVKNSWGTTWGEQGYIKMARNQNNQCGI 330 Query: 95 ATKASYPLV 69 AT +SYP V Sbjct: 331 ATASSYPTV 339
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U) Length = 334 Score = 110 bits (275), Expect = 1e-24 Identities = 52/74 (70%), Positives = 57/74 (77%), Gaps = 4/74 (5%) Frame = -2 Query: 278 KSGIYNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSWGTVWGIDGYIKMSKDAN 111 KSGIY EPDCSS LDHGVLVVGYG E + S YWLVKNSWG WG +GY+K++KD N Sbjct: 261 KSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKN 320 Query: 110 NQCGIATKASYPLV 69 N CGIAT ASYP V Sbjct: 321 NHCGIATAASYPNV 334
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 109 bits (272), Expect = 2e-24 Identities = 49/73 (67%), Positives = 57/73 (78%), Gaps = 3/73 (4%) Frame = -2 Query: 278 KSGIYNEPDCSSTQLDHGVLVVGYG---TEDGSNYWLVKNSWGTVWGIDGYIKMSKDANN 108 KSGIY +PDCSS LDHGVLVVGYG T+ + +W+VKNSWG WG +GY+KM+KD NN Sbjct: 261 KSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGPEWGWNGYVKMAKDQNN 320 Query: 107 QCGIATKASYPLV 69 CGIAT ASYP V Sbjct: 321 HCGIATAASYPTV 333
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic protein 2) (CP-2) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 109 bits (272), Expect = 2e-24 Identities = 50/73 (68%), Positives = 57/73 (78%), Gaps = 4/73 (5%) Frame = -2 Query: 275 SGIYNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSWGTVWGIDGYIKMSKDANN 108 SGIY EP+CSS LDHGVLVVGYG E + YWLVKNSWG WG+DGYIK++KD NN Sbjct: 261 SGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAKDRNN 320 Query: 107 QCGIATKASYPLV 69 CG+AT ASYP+V Sbjct: 321 HCGLATAASYPIV 333
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 217 Score = 109 bits (272), Expect = 2e-24 Identities = 50/71 (70%), Positives = 56/71 (78%), Gaps = 1/71 (1%) Frame = -2 Query: 278 KSGIYNEPDCSSTQLDHGVLVVGYGTEDGSN-YWLVKNSWGTVWGIDGYIKMSKDANNQC 102 KSGIY +PDCSS LDHGVLVVGYG E +N +W+VKNSWG WG GY+KM+KD NN C Sbjct: 147 KSGIYYDPDCSSKDLDHGVLVVGYGFEGTNNKFWIVKNSWGPEWGNKGYVKMAKDQNNHC 206 Query: 101 GIATKASYPLV 69 GIAT ASYP V Sbjct: 207 GIATAASYPTV 217
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 108 bits (269), Expect = 5e-24 Identities = 49/74 (66%), Positives = 57/74 (77%), Gaps = 4/74 (5%) Frame = -2 Query: 278 KSGIYNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSWGTVWGIDGYIKMSKDAN 111 KSGIY +PDCSS LDHGVLVVGYG E + S +W+VKNSWG WG +GY+KM+KD N Sbjct: 261 KSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPEWGWNGYVKMAKDQN 320 Query: 110 NQCGIATKASYPLV 69 N CGI+T ASYP V Sbjct: 321 NHCGISTAASYPTV 334
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 107 bits (268), Expect = 7e-24 Identities = 49/74 (66%), Positives = 55/74 (74%), Gaps = 4/74 (5%) Frame = -2 Query: 278 KSGIYNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSWGTVWGIDGYIKMSKDAN 111 K GIY EPDCSS +DHGVLVVGYG E D + YWLVKNSWG WG+ GY+KM+KD Sbjct: 260 KEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRR 319 Query: 110 NQCGIATKASYPLV 69 N CGIA+ ASYP V Sbjct: 320 NHCGIASAASYPTV 333
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor Length = 323 Score = 107 bits (267), Expect = 9e-24 Identities = 47/69 (68%), Positives = 54/69 (78%) Frame = -2 Query: 275 SGIYNEPDCSSTQLDHGVLVVGYGTEDGSNYWLVKNSWGTVWGIDGYIKMSKDANNQCGI 96 SG+Y EP CS + LDH VL VGYG+E G ++WLVKNSW T WG GYIKMS++ NN CGI Sbjct: 255 SGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGI 314 Query: 95 ATKASYPLV 69 AT ASYPLV Sbjct: 315 ATVASYPLV 323
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor Length = 322 Score = 106 bits (265), Expect = 1e-23 Identities = 45/69 (65%), Positives = 54/69 (78%) Frame = -2 Query: 275 SGIYNEPDCSSTQLDHGVLVVGYGTEDGSNYWLVKNSWGTVWGIDGYIKMSKDANNQCGI 96 +G+Y EP CSS+QLDH VL VGYG+E G ++WLVKNSW T WG GYIKM+++ NN CGI Sbjct: 254 TGVYYEPSCSSSQLDHAVLAVGYGSEGGQDFWLVKNSWATSWGESGYIKMARNRNNNCGI 313 Query: 95 ATKASYPLV 69 AT A YP V Sbjct: 314 ATDACYPTV 322
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 106 bits (264), Expect = 2e-23 Identities = 48/74 (64%), Positives = 56/74 (75%), Gaps = 4/74 (5%) Frame = -2 Query: 278 KSGIYNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSWGTVWGIDGYIKMSKDAN 111 KSGIY +PDCS LDHGVLVVGYG E + + +W+VKNSWG WG +GY+KM+KD N Sbjct: 261 KSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKNSWGPEWGWNGYVKMAKDQN 320 Query: 110 NQCGIATKASYPLV 69 N CGIAT ASYP V Sbjct: 321 NHCGIATAASYPTV 334
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,506,605 Number of Sequences: 369166 Number of extensions: 669128 Number of successful extensions: 2077 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1932 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1984 length of database: 68,354,980 effective HSP length: 62 effective length of database: 56,901,410 effective search space used: 1707042300 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)