Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_G07
(326 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 137 1e-32
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 135 2e-32
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 134 8e-32
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 134 8e-32
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 132 2e-31
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 131 5e-31
sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 129 2e-30
sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 129 2e-30
sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 129 2e-30
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 128 4e-30
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 137 bits (344), Expect = 1e-32
Identities = 62/87 (71%), Positives = 71/87 (81%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGT-EDGNNYWLVKNSWGTVW 178
P+SVAIDAS+ SFQLY G+YNEP+C LDHGVLVVGYGT E G +YWLVKNSWGT W
Sbjct: 253 PVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVKNSWGTTW 312
Query: 179 GINGYIKMSKDANNQCGIATKASYPLV 259
G GYIKM+++ NNQCGIAT +SYP V
Sbjct: 313 GEQGYIKMARNQNNQCGIATASSYPTV 339
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 135 bits (341), Expect = 2e-32
Identities = 63/89 (70%), Positives = 70/89 (78%), Gaps = 3/89 (3%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYG---TEDGNNYWLVKNSWGT 172
PISVAIDA + SFQ YKSGIY +PDCSS LDHGVLVVGYG T+ N +W+VKNSWG
Sbjct: 245 PISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGP 304
Query: 173 VWGINGYIKMSKDANNQCGIATKASYPLV 259
WG NGY+KM+KD NN CGIAT ASYP V
Sbjct: 305 EWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 134 bits (336), Expect = 8e-32
Identities = 64/90 (71%), Positives = 70/90 (77%), Gaps = 4/90 (4%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGNN----YWLVKNSWG 169
PISVA+DA + SFQ YKSGIY EPDCSS LDHGVLVVGYG E N+ YWLVKNSWG
Sbjct: 245 PISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWG 304
Query: 170 TVWGINGYIKMSKDANNQCGIATKASYPLV 259
WG NGY+K++KD NN CGIAT ASYP V
Sbjct: 305 PEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 134 bits (336), Expect = 8e-32
Identities = 63/87 (72%), Positives = 69/87 (79%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGNN-YWLVKNSWGTVW 178
PISVAIDA + SFQ YKSGIY +PDCSS LDHGVLVVGYG E NN +W+VKNSWG W
Sbjct: 131 PISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTNNKFWIVKNSWGPEW 190
Query: 179 GINGYIKMSKDANNQCGIATKASYPLV 259
G GY+KM+KD NN CGIAT ASYP V
Sbjct: 191 GNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 132 bits (332), Expect = 2e-31
Identities = 62/90 (68%), Positives = 69/90 (76%), Gaps = 4/90 (4%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTE----DGNNYWLVKNSWG 169
PISVAIDA + SFQ YKSGIY +PDCS LDHGVLVVGYG E + N +W+VKNSWG
Sbjct: 245 PISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKNSWG 304
Query: 170 TVWGINGYIKMSKDANNQCGIATKASYPLV 259
WG NGY+KM+KD NN CGIAT ASYP V
Sbjct: 305 PEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 131 bits (329), Expect = 5e-31
Identities = 61/90 (67%), Positives = 70/90 (77%), Gaps = 4/90 (4%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTE----DGNNYWLVKNSWG 169
PISVAIDA + SFQ YKSGIY +PDCSS LDHGVLVVGYG E + + +W+VKNSWG
Sbjct: 245 PISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWG 304
Query: 170 TVWGINGYIKMSKDANNQCGIATKASYPLV 259
WG NGY+KM+KD NN CGI+T ASYP V
Sbjct: 305 PEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
Cathepsin L heavy chain; Cathepsin L light chain]
Length = 333
Score = 129 bits (325), Expect = 2e-30
Identities = 61/90 (67%), Positives = 67/90 (74%), Gaps = 4/90 (4%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTE----DGNNYWLVKNSWG 169
PISVAIDA + SF YK GIY EPDCSS +DHGVLVVGYG E D N YWLVKNSWG
Sbjct: 244 PISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWG 303
Query: 170 TVWGINGYIKMSKDANNQCGIATKASYPLV 259
WG+ GY+KM+KD N CGIA+ ASYP V
Sbjct: 304 EEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
L heavy chain; Cathepsin L light chain]
Length = 341
Score = 129 bits (325), Expect = 2e-30
Identities = 58/87 (66%), Positives = 69/87 (79%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGT-EDGNNYWLVKNSWGTVW 178
P+SVAIDAS+ SFQ Y G+YNEP C + LDHGVLVVG+GT E G +YWLVKNSWGT W
Sbjct: 255 PVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTW 314
Query: 179 GINGYIKMSKDANNQCGIATKASYPLV 259
G G+IKM ++ NQCGIA+ +SYPLV
Sbjct: 315 GDKGFIKMLRNKENQCGIASASSYPLV 341
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor
Length = 322
Score = 129 bits (324), Expect = 2e-30
Identities = 58/86 (67%), Positives = 69/86 (80%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGNNYWLVKNSWGTVWG 181
PISVAIDAS+ SFQ Y +G+Y EP CSS+QLDH VL VGYG+E G ++WLVKNSW T WG
Sbjct: 237 PISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGSEGGQDFWLVKNSWATSWG 296
Query: 182 INGYIKMSKDANNQCGIATKASYPLV 259
+GYIKM+++ NN CGIAT A YP V
Sbjct: 297 ESGYIKMARNRNNNCGIATDACYPTV 322
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 128 bits (322), Expect = 4e-30
Identities = 58/86 (67%), Positives = 67/86 (77%)
Frame = +2
Query: 2 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGNNYWLVKNSWGTVWG 181
PISV IDA++ SFQ Y SG+Y EP CS + LDH VL VGYG+E G ++WLVKNSW T WG
Sbjct: 238 PISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWG 297
Query: 182 INGYIKMSKDANNQCGIATKASYPLV 259
GYIKMS++ NN CGIAT ASYPLV
Sbjct: 298 DAGYIKMSRNRNNNCGIATVASYPLV 323
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,812,326
Number of Sequences: 369166
Number of extensions: 795015
Number of successful extensions: 2335
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2134
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2193
length of database: 68,354,980
effective HSP length: 77
effective length of database: 54,130,385
effective search space used: 1678041935
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)