Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_01003 (878 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8VDL4|ADPGK_MOUSE ADP-dependent glucokinase (ADPGK) (AD... 110 5e-24 sp|Q9BRR6|ADPGK_HUMAN ADP-dependent glucokinase (ADPGK) (AD... 108 3e-23 sp|Q9V1A6|K6PF_PYRAB ADP-specific phosphofructokinase (ADP-... 58 3e-08 sp|O59355|K6PF_PYRHO ADP-specific phosphofructokinase (ADP-... 58 3e-08 sp|Q9V2Z7|K6PF_PYRFU ADP-specific phosphofructokinase (ADP-... 58 4e-08 sp|Q977Q3|K6PF_THELI ADP-specific phosphofructokinase (ADP-... 58 4e-08 sp|Q5JD05|K6PF_PYRKO ADP-specific phosphofructokinase (ADP-... 54 6e-07 sp|Q9HH12|K6PF_THEZI ADP-specific phosphofructokinase (ADP-... 53 1e-06 sp|Q5JE39|GLKA_PYRKO ADP-dependent glucokinase (ADPGK) (ADP... 46 1e-04 sp|Q9V2Z6|GLKA_PYRFU ADP-dependent glucokinase (ADPGK) (ADP... 45 3e-04
>sp|Q8VDL4|ADPGK_MOUSE ADP-dependent glucokinase (ADPGK) (ADP-GK) Length = 496 Score = 110 bits (275), Expect = 5e-24 Identities = 80/254 (31%), Positives = 122/254 (48%), Gaps = 3/254 (1%) Frame = +1 Query: 4 LEKLESKIKAFKPDIFVLGGLQMMDGFPYQKGEMNEQINRLERFLATIPKDVPIHFEMAS 183 LE S ++ F+PD+ VL GL MM+G K +++ + ++ IP +P+H E+AS Sbjct: 243 LEVFVSSLEEFQPDLVVLSGLHMMEG--QSKELQRKRLLEVVTAISDIPTGIPVHLELAS 300 Query: 184 FIEKQFFLKLKNQ-IIPYADSLGFNEQELPNLFSILDSDSITTLST--AYPRTSHMLDHM 354 ++ + +Q + P SLG NEQEL L S S ++LS+ P + D + Sbjct: 301 MTNRELMSSIVHQQVFPAVASLGLNEQELLFL-SQSASGPHSSLSSWDGVPDVGMVSDIL 359 Query: 355 RRVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYT 534 W I+ + S + L+R+H HT+ Y I+ T W + +AVA + VA Sbjct: 360 --FW-ILKEHGRSENRASDLTRIHFHTLVYHILATV--DGHWANQLAAVAAGARVAGTQA 414 Query: 535 CGIHNVDIERSKLLMDDSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVI 714 C +D R L F+ S + + R+ N PV W + PVLVC + Sbjct: 415 CATETIDTNRVSLRAPQEFTTSHLESGSRIVLNPDKPVVEWHREGITFHFTPVLVCKDPV 474 Query: 715 RTVGGGDNISSAAL 756 RTVG GD IS+ L Sbjct: 475 RTVGLGDAISAEGL 488
>sp|Q9BRR6|ADPGK_HUMAN ADP-dependent glucokinase (ADPGK) (ADP-GK) (RbBP-35) Length = 497 Score = 108 bits (269), Expect = 3e-23 Identities = 78/253 (30%), Positives = 114/253 (45%), Gaps = 2/253 (0%) Frame = +1 Query: 4 LEKLESKIKAFKPDIFVLGGLQMMDGFPYQKGEMNEQINRLERFLATIPKDVPIHFEMAS 183 LE S ++ F+PD+ VL GL MM+G K +++ + ++ IP +P+H E+AS Sbjct: 243 LEVFVSSLEEFQPDLVVLSGLHMMEG--QSKELQRKRLLEVVTSISDIPTGIPVHLELAS 300 Query: 184 FIEKQFFLKLKNQ-IIPYADSLGFNEQELPNLFSILDSDSITTLS-TAYPRTSHMLDHMR 357 ++ + +Q + P SLG NEQEL L + S P + D + Sbjct: 301 MTNRELMSSIVHQQVFPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDIL- 359 Query: 358 RVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYTC 537 W I+ + S + L+R+H HT+ Y I+ T W + +AVA + VA C Sbjct: 360 -FW-ILKEHGRSKSRASDLTRIHFHTLVYHILATV--DGHWANQLAAVAAGARVAGTQAC 415 Query: 538 GIHNVDIERSKLLMDDSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIR 717 +D R L F S R+ N PV W + PVLVC IR Sbjct: 416 ATETIDTSRVSLRAPQEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIR 475 Query: 718 TVGGGDNISSAAL 756 TVG GD IS+ L Sbjct: 476 TVGLGDAISAEGL 488
>sp|Q9V1A6|K6PF_PYRAB ADP-specific phosphofructokinase (ADP-dependent phosphofructokinase) (ADP-Pfk) Length = 451 Score = 58.2 bits (139), Expect = 3e-08 Identities = 57/217 (26%), Positives = 97/217 (44%), Gaps = 6/217 (2%) Frame = +1 Query: 127 ERFLATIPKDVPIHFEMASFIEKQFFLKLKNQIIPYADSLGFNEQELPNLFSILDSDSIT 306 E ++ +DV +H E+AS +++ K+ I+P ADS+G +E E+ L S+L + Sbjct: 246 EDIISLKEEDVKVHVELASIQDRKLRKKVITNILPIADSVGIDEAEIAQLLSVLGYRDLA 305 Query: 307 TLSTAYPRTSHMLDHMRRVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHS 486 Y R L+ II+D+L L +HTI Y + +T++ + Sbjct: 306 DRIFTYNR----LEDSILGGMIILDEL-------NFEILQVHTIYYLMYITHRDNPLSEE 354 Query: 487 S--RSAVAKASLVAHRYTCGIHNVDIERSKLLMDDSFSIS-EIPNSPR---VHFNFTDPV 648 +S +L A R + G DI R + + I ++P + R V F + Sbjct: 355 ELMKSLEFGTTLAAARASLG----DINR-----PEDYEIGLKVPFNERSEYVKLRFEEAK 405 Query: 649 SCWEERELEICVAPVLVCTKVIRTVGGGDNISSAALL 759 + RE ++ V P + + TVG GD IS+ A + Sbjct: 406 TKLRMREYKVVVIPTRLVPNPVLTVGLGDTISAGAFI 442
>sp|O59355|K6PF_PYRHO ADP-specific phosphofructokinase (ADP-dependent phosphofructokinase) (ADP-Pfk) Length = 450 Score = 58.2 bits (139), Expect = 3e-08 Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 5/211 (2%) Frame = +1 Query: 151 KDVPIHFEMASFIEKQFFLKLKNQIIPYADSLGFNEQELPNLFSILDSDSITTLSTAYPR 330 KDV IH E AS +++ K+ I+P+ DS+G +E E+ + S+L + Y R Sbjct: 253 KDVKIHVEFASVQDRKLRKKIITNILPFVDSVGIDEAEIAQILSVLGYRELADRIFTYNR 312 Query: 331 TSHMLDHMRRVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHS--SRSAVA 504 L+ II+D+L L +HT Y + +T++ + ++S Sbjct: 313 ----LEDSILGGMIILDEL-------NFEILQVHTTYYLMYITHRDNPLSEEELAKSLEF 361 Query: 505 KASLVAHRYTCGIHNVDIERSKLLMDDSFSISEIPNSPR---VHFNFTDPVSCWEERELE 675 +L A R + G DI DD ++P + R V F + S RE + Sbjct: 362 GTTLAAARASLG----DIRGP----DDYKVGLKVPFNERSEYVKLRFEEAKSRLRMREYK 413 Query: 676 ICVAPVLVCTKVIRTVGGGDNISSAALLNQL 768 + V P + + TVG GD IS+ A L L Sbjct: 414 VVVIPTRLVQNPVLTVGLGDTISAGAFLTYL 444
>sp|Q9V2Z7|K6PF_PYRFU ADP-specific phosphofructokinase (ADP-dependent phosphofructokinase) (ADP-Pfk) Length = 454 Score = 57.8 bits (138), Expect = 4e-08 Identities = 66/270 (24%), Positives = 116/270 (42%), Gaps = 13/270 (4%) Frame = +1 Query: 4 LEKLESK--IKAFKPDIFVLGGLQMMDGFP-----YQKG-EMNEQINRLERFLATIPK-- 153 + ++E+K ++ F P+I + ++ G+ Y G + N + R + + + K Sbjct: 197 ISRIETKDELRKFLPEIGEMVDGAILSGYQGIRLQYSDGKDANYYLRRAKEDIRLLKKNK 256 Query: 154 DVPIHFEMASFIEKQFFLKLKNQIIPYADSLGFNEQELPNLFSILDSDSITTLSTAYPRT 333 D+ IH E AS +++ K+ N I P DS+G +E E+ + S+L + Y R Sbjct: 257 DIKIHVEFASIQDRRLRKKVVNNIFPMVDSVGMDEAEIAYILSVLGYSDLADRIFMYNRI 316 Query: 334 SH-MLDHMRRVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHSS--RSAVA 504 +L M II+D+L L +HTI Y + +T++ + RS Sbjct: 317 EDAILGGM-----IILDEL-------NFEILQVHTIYYLMYITHRDNPLSEEELMRSLDF 364 Query: 505 KASLVAHRYTCGIHNVDIERSKLLMDDSFSISEIPNSPRVHFNFTDPVSCWEERELEICV 684 L A R + G N D K+ M S+ S + F + +E ++ + Sbjct: 365 GTILAATRASLGDIN-DPRDVKVGM----SVPYNERSEYIKLRFEEAKRKLRLKEYKVVI 419 Query: 685 APVLVCTKVIRTVGGGDNISSAALLNQLRI 774 P + + TVG GD IS+ L+ L + Sbjct: 420 VPTRLVPNPVSTVGLGDTISTGTFLSYLSL 449
>sp|Q977Q3|K6PF_THELI ADP-specific phosphofructokinase (ADP-dependent phosphofructokinase) (ADP-Pfk) Length = 459 Score = 57.8 bits (138), Expect = 4e-08 Identities = 60/261 (22%), Positives = 112/261 (42%), Gaps = 10/261 (3%) Frame = +1 Query: 22 KIKAFKPDI------FVLGGLQMMDGFPYQKGEMNEQINRLERFLATIPK--DVPIHFEM 177 ++K + P+I +L G Q + + + N + + + + + K D+ IH E Sbjct: 210 ELKPYLPEIGEMVDGAILSGYQGLRRYYSDGKDANYYLRKAKEDIKLLKKKKDIKIHVEF 269 Query: 178 ASFIEKQFFLKLKNQIIPYADSLGFNEQELPNLFSILDSDSITTLSTAYPRTSHMLDHMR 357 AS +++ K+ I P DS+G +E E+ ++ S+L ++ Y R + + Sbjct: 270 ASIQDRELRKKVIYNIFPLVDSVGMDEAEIAHILSVLGYRELSDRIFTYNRIEDAVLGAK 329 Query: 358 RVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHS--SRSAVAKASLVAHRY 531 I++D+L L L +HTI Y + +T+ + ++S +L A R Sbjct: 330 ----ILLDEL-------NLEILQVHTIYYLMYITHNDNPLTEEELTKSLEVGTTLAAARA 378 Query: 532 TCGIHNVDIERSKLLMDDSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKV 711 G DI+R + + +I V F + + RE +I + P + Sbjct: 379 FLG----DIKRPE-DVKVGLNIPFNEKGEYVKLRFEEAKAKMRTREYKIVIIPTRLVRNP 433 Query: 712 IRTVGGGDNISSAALLNQLRI 774 + TVG GD IS+ A + L + Sbjct: 434 VSTVGLGDTISAGAFASYLSL 454
>sp|Q5JD05|K6PF_PYRKO ADP-specific phosphofructokinase (ADP-dependent phosphofructokinase) (ADP-Pfk) Length = 461 Score = 53.9 bits (128), Expect = 6e-07 Identities = 64/270 (23%), Positives = 111/270 (41%), Gaps = 19/270 (7%) Frame = +1 Query: 16 ESKIKAFKPDI------FVLGG-----LQMMDGFP--YQKGEMNEQINRLERFLATIPKD 156 E ++K F P+I +L G L+ DG Y E + I L+R KD Sbjct: 208 EPELKPFLPEIGQRVDGAILSGYQGIKLRYSDGKDANYYLREAKKDILLLKR-----EKD 262 Query: 157 VPIHFEMASFIEKQFFLKLKNQIIPYADSLGFNEQELPNLFSILDSDSITTLSTAYPRTS 336 V +H E AS ++ K+ + P DS+G +E E+ + S L D + Y R Sbjct: 263 VKVHLEFASIQNRELRKKVIYNLFPLVDSVGMDEAEIAYVLSALGYDKLAERIFTYNR-- 320 Query: 337 HMLDHMRRVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHSS--RSAVAKA 510 ++ +I++D++ L L +HTI Y + + + ++ + +S Sbjct: 321 --IEDTVLGGKILIDEM-------NLELLQIHTIYYIMYIAHANNPLSEAELRQSLELAT 371 Query: 511 SLVAHRYTCGIHNVDIERSKLLMDDSFSIS-EIPNSPR---VHFNFTDPVSCWEERELEI 678 +L A R + G + D S+ +P + R V F + +E ++ Sbjct: 372 TLAASRASLG---------DIASPDQISVGMNVPYNERGEYVKLRFEEAKRRLRTKEYKL 422 Query: 679 CVAPVLVCTKVIRTVGGGDNISSAALLNQL 768 + P + + TVG GD IS+ A + L Sbjct: 423 VIIPTRLVQNPVSTVGLGDTISTGAFTSYL 452
>sp|Q9HH12|K6PF_THEZI ADP-specific phosphofructokinase (ADP-dependent phosphofructokinase) (ADP-Pfk) Length = 461 Score = 53.1 bits (126), Expect = 1e-06 Identities = 51/212 (24%), Positives = 88/212 (41%), Gaps = 6/212 (2%) Frame = +1 Query: 151 KDVPIHFEMASFIEKQFFLKLKNQIIPYADSLGFNEQELPNLFSILDSDSITTLSTAYPR 330 KD+ +H E AS ++ K+ + P ADS+G +E E+ + S L D + Y R Sbjct: 261 KDLKVHLEFASIQSRELRKKVIYNLFPLADSVGMDEAEIAYVLSALGYDELADRIFTYNR 320 Query: 331 TSHMLDHMRRVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHSS--RSAVA 504 ++ +I++D++ L L +HTI Y + +T+ + RS Sbjct: 321 ----IEDTVLGGKILLDEM-------NLDVLQIHTIYYIMYITHADNPLSEEELRRSLEL 369 Query: 505 KASLVAHRYTCGIHNVDIERSKLLMDDSFSIS-EIPNSPR---VHFNFTDPVSCWEEREL 672 +L A R + G + D I +P + R V F + +E Sbjct: 370 ATTLAASRASLG---------DITSPDQIEIGLRVPYNERGEYVKLRFEEAKRKLRTKEY 420 Query: 673 EICVAPVLVCTKVIRTVGGGDNISSAALLNQL 768 ++ + P + + TVG GD IS+ A + L Sbjct: 421 KLVIIPTRLVQNPVSTVGLGDTISTGAFASYL 452
>sp|Q5JE39|GLKA_PYRKO ADP-dependent glucokinase (ADPGK) (ADP-GK) Length = 453 Score = 46.2 bits (108), Expect = 1e-04 Identities = 50/249 (20%), Positives = 101/249 (40%), Gaps = 1/249 (0%) Frame = +1 Query: 31 AFKPDIFVLGGLQMMDGFPYQKGEMNEQINRLERFLATIP-KDVPIHFEMASFIEKQFFL 207 A K ++ ++ GLQ + +G E ++ L + K +P H E A F + Sbjct: 222 AEKTELAIISGLQALT-----EGNYREPFETIKEHLDVLEGKGIPAHLEFA-FTPDETVR 275 Query: 208 KLKNQIIPYADSLGFNEQELPNLFSILDSDSITTLSTAYPRTSHMLDHMRRVWEIIVDQL 387 K ++ S+G NE EL ++ ++ ++ A+ ++ V + ++ Sbjct: 276 KEILGVLGKFWSVGLNEVELASIMDVMGEKTLAEKLLAHDPVDPIV-----VTKAMLKLA 330 Query: 388 PSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYTCGIHNVDIERS 567 G R R+H HT GY + +T+ +F + A A+ A + N+D Sbjct: 331 EKTGVR----RIHFHTYGYYLALTDYRGEFVRDALLFAALAA-AAKAKLGDVRNIDDVVK 385 Query: 568 KLLMDDSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISS 747 + + + + + + + ++ E ++ P + K TVG GD ISS Sbjct: 386 AMDVPVNEKAKGVEEALTKEYGMENGIA--EVNGYQLAFIPTKIVAKPKSTVGIGDTISS 443 Query: 748 AALLNQLRI 774 +A + + + Sbjct: 444 SAFVGEFAL 452
>sp|Q9V2Z6|GLKA_PYRFU ADP-dependent glucokinase (ADPGK) (ADP-GK) Length = 455 Score = 45.1 bits (105), Expect = 3e-04 Identities = 40/205 (19%), Positives = 84/205 (40%) Frame = +1 Query: 151 KDVPIHFEMASFIEKQFFLKLKNQIIPYADSLGFNEQELPNLFSILDSDSITTLSTAYPR 330 +++P+H E A +++ ++ N ++ S+G NE EL ++ IL + A+ Sbjct: 259 REIPVHLEFAFTPDEKVREEILN-VLGMFYSVGLNEVELASIMEILGEKKLAKELLAHDP 317 Query: 331 TSHMLDHMRRVWEIIVDQLPSNGTRNKLSRLHLHTIGYQIIMTNKHSKFWHSSRSAVAKA 510 + + + + + + R+H HT GY + +T + + A A Sbjct: 318 VDPIA---------VTEAMLKLAKKTGVKRIHFHTYGYYLALTEYKGEHVRDALLFAALA 368 Query: 511 SLVAHRYTCGIHNVDIERSKLLMDDSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAP 690 + A I +++ R + + +++ R + + + E +I P Sbjct: 369 A-AAKAMKGNITSLEEIREATSVPVNEKATQVEEKLRAEYGIKEGIG--EVEGYQIAFIP 425 Query: 691 VLVCTKVIRTVGGGDNISSAALLNQ 765 + K TVG GD ISS+A + + Sbjct: 426 TKIVAKPKSTVGIGDTISSSAFIGE 450
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 101,972,426 Number of Sequences: 369166 Number of extensions: 2068959 Number of successful extensions: 4734 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4571 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4714 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 8742211660 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)