Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_C16
(711 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8VDL4|ADPGK_MOUSE ADP-dependent glucokinase (ADPGK) (AD... 71 2e-12
sp|Q9BRR6|ADPGK_HUMAN ADP-dependent glucokinase (ADPGK) (AD... 69 2e-11
sp|Q9UYQ3|GLKA_PYRAB ADP-dependent glucokinase (ADPGK) (ADP... 38 0.023
sp|Q9V2Z6|GLKA_PYRFU ADP-dependent glucokinase (ADPGK) (ADP... 37 0.040
sp|Q5JE39|GLKA_PYRKO ADP-dependent glucokinase (ADPGK) (ADP... 37 0.052
sp|Q977Q3|K6PF_THELI ADP-specific phosphofructokinase (ADP-... 36 0.089
sp|O58328|GLKA_PYRHO ADP-dependent glucokinase (ADPGK) (ADP... 36 0.12
sp|Q9V1A6|K6PF_PYRAB ADP-specific phosphofructokinase (ADP-... 34 0.34
sp|O59355|K6PF_PYRHO ADP-specific phosphofructokinase (ADP-... 33 0.57
sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor precursor... 33 0.75
>sp|Q8VDL4|ADPGK_MOUSE ADP-dependent glucokinase (ADPGK) (ADP-GK)
Length = 496
Score = 71.2 bits (173), Expect = 2e-12
Identities = 57/179 (31%), Positives = 81/179 (45%), Gaps = 2/179 (1%)
Frame = +3
Query: 87 F*IILLLGFNEQELPNLFSILDSDSITTLST--AYPRTSHMLDHMRRVWEIIVDQLPSNG 260
F + LG NEQEL L S S ++LS+ P + D + W I+ + S
Sbjct: 316 FPAVASLGLNEQELLFL-SQSASGPHSSLSSWDGVPDVGMVSDIL--FW-ILKEHGRSEN 371
Query: 261 TRNKLSRLHLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYTCGIHNVDIERSKLLM 440
+ L+R+H HT+ Y I+ T W + +AVA + VA C +D R L
Sbjct: 372 RASDLTRIHFHTLVYHILATV--DGHWANQLAAVAAGARVAGTQACATETIDTNRVSLRA 429
Query: 441 DDSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAAL 617
F+ S + + R+ N PV W + PVLVC +RTVG GD IS+ L
Sbjct: 430 PQEFTTSHLESGSRIVLNPDKPVVEWHREGITFHFTPVLVCKDPVRTVGLGDAISAEGL 488
>sp|Q9BRR6|ADPGK_HUMAN ADP-dependent glucokinase (ADPGK) (ADP-GK) (RbBP-35)
Length = 497
Score = 68.6 bits (166), Expect = 2e-11
Identities = 55/178 (30%), Positives = 73/178 (41%), Gaps = 1/178 (0%)
Frame = +3
Query: 87 F*IILLLGFNEQELPNLFSILDSDSITTLS-TAYPRTSHMLDHMRRVWEIIVDQLPSNGT 263
F + LG NEQEL L + S P + D + W I+ + S
Sbjct: 316 FPAVTSLGLNEQELLFLTQSASGPHSSLSSWNGVPDVGMVSDIL--FW-ILKEHGRSKSR 372
Query: 264 RNKLSRLHLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYTCGIHNVDIERSKLLMD 443
+ L+R+H HT+ Y I+ T W + +AVA + VA C +D R L
Sbjct: 373 ASDLTRIHFHTLVYHILATV--DGHWANQLAAVAAGARVAGTQACATETIDTSRVSLRAP 430
Query: 444 DSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAAL 617
F S R+ N PV W + PVLVC IRTVG GD IS+ L
Sbjct: 431 QEFMTSHSEAGSRIVLNPNKPVVEWHREGISFHFTPVLVCKDPIRTVGLGDAISAEGL 488
>sp|Q9UYQ3|GLKA_PYRAB ADP-dependent glucokinase (ADPGK) (ADP-GK)
Length = 452
Score = 38.1 bits (87), Expect = 0.023
Identities = 44/187 (23%), Positives = 79/187 (42%), Gaps = 5/187 (2%)
Frame = +3
Query: 93 IILLLGFNEQELPNLFSILD----SDSITTLSTAYPRTSHMLDHMRRVWEIIVDQLPSNG 260
++ +G NE EL ++ I++ +D I A P +++ + ++ E V+
Sbjct: 283 LVYSVGLNEVELASVLEIMNERELADRILAKDPADPVA--VIEGLMKLIEEGVE------ 334
Query: 261 TRNKLSRLHLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYTCG-IHNVDIERSKLL 437
R+H HT GY + +T + H + + A A + G I +D R L
Sbjct: 335 ------RIHFHTYGYYLAITKYRGE--HVRDALLFSALAAATKAMLGNIEKLDDLRKGLE 386
Query: 438 MDDSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAAL 617
+ E+ + FN + E + +I P + K TVG GD ISS+A
Sbjct: 387 VPIGRQGLEVYEVVKREFNVEKGIG--EVGDYQIAFVPTKIVEKPKSTVGIGDTISSSAF 444
Query: 618 LNQLRIS 638
+++ +S
Sbjct: 445 VSEFSLS 451
>sp|Q9V2Z6|GLKA_PYRFU ADP-dependent glucokinase (ADPGK) (ADP-GK)
Length = 455
Score = 37.4 bits (85), Expect = 0.040
Identities = 34/174 (19%), Positives = 67/174 (38%)
Frame = +3
Query: 105 LGFNEQELPNLFSILDSDSITTLSTAYPRTSHMLDHMRRVWEIIVDQLPSNGTRNKLSRL 284
+G NE EL ++ IL + A+ + + + + + + R+
Sbjct: 289 VGLNEVELASIMEILGEKKLAKELLAHDPVDPIA---------VTEAMLKLAKKTGVKRI 339
Query: 285 HLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYTCGIHNVDIERSKLLMDDSFSISE 464
H HT GY + +T + + A A+ A I +++ R + + ++
Sbjct: 340 HFHTYGYYLALTEYKGEHVRDALLFAALAA-AAKAMKGNITSLEEIREATSVPVNEKATQ 398
Query: 465 IPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAALLNQ 626
+ R + + + E +I P + K TVG GD ISS+A + +
Sbjct: 399 VEEKLRAEYGIKEGIG--EVEGYQIAFIPTKIVAKPKSTVGIGDTISSSAFIGE 450
>sp|Q5JE39|GLKA_PYRKO ADP-dependent glucokinase (ADPGK) (ADP-GK)
Length = 453
Score = 37.0 bits (84), Expect = 0.052
Identities = 34/177 (19%), Positives = 72/177 (40%)
Frame = +3
Query: 105 LGFNEQELPNLFSILDSDSITTLSTAYPRTSHMLDHMRRVWEIIVDQLPSNGTRNKLSRL 284
+G NE EL ++ ++ ++ A+ ++ V + ++ G R R+
Sbjct: 288 VGLNEVELASIMDVMGEKTLAEKLLAHDPVDPIV-----VTKAMLKLAEKTGVR----RI 338
Query: 285 HLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYTCGIHNVDIERSKLLMDDSFSISE 464
H HT GY + +T+ +F + A A+ A + N+D + + +
Sbjct: 339 HFHTYGYYLALTDYRGEFVRDALLFAALAA-AAKAKLGDVRNIDDVVKAMDVPVNEKAKG 397
Query: 465 IPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAALLNQLRI 635
+ + + + ++ E ++ P + K TVG GD ISS+A + + +
Sbjct: 398 VEEALTKEYGMENGIA--EVNGYQLAFIPTKIVAKPKSTVGIGDTISSSAFVGEFAL 452
>sp|Q977Q3|K6PF_THELI ADP-specific phosphofructokinase (ADP-dependent
phosphofructokinase) (ADP-Pfk)
Length = 459
Score = 36.2 bits (82), Expect = 0.089
Identities = 42/185 (22%), Positives = 78/185 (42%), Gaps = 2/185 (1%)
Frame = +3
Query: 87 F*IILLLGFNEQELPNLFSILDSDSITTLSTAYPRTSHMLDHMRRVWEIIVDQLPSNGTR 266
F ++ +G +E E+ ++ S+L ++ Y R + + I++D+L
Sbjct: 286 FPLVDSVGMDEAEIAHILSVLGYRELSDRIFTYNRIEDAVLGAK----ILLDEL------ 335
Query: 267 NKLSRLHLHTIGYQIIMTNKHSKFWHS--SRSAVAKASLVAHRYTCGIHNVDIERSKLLM 440
L L +HTI Y + +T+ + ++S +L A R G DI+R + +
Sbjct: 336 -NLEILQVHTIYYLMYITHNDNPLTEEELTKSLEVGTTLAAARAFLG----DIKRPEDVK 390
Query: 441 DDSFSISEIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAALL 620
+I V F + + RE +I + P + + TVG GD IS+ A
Sbjct: 391 V-GLNIPFNEKGEYVKLRFEEAKAKMRTREYKIVIIPTRLVRNPVSTVGLGDTISAGAFA 449
Query: 621 NQLRI 635
+ L +
Sbjct: 450 SYLSL 454
>sp|O58328|GLKA_PYRHO ADP-dependent glucokinase (ADPGK) (ADP-GK)
Length = 457
Score = 35.8 bits (81), Expect = 0.12
Identities = 40/178 (22%), Positives = 72/178 (40%), Gaps = 1/178 (0%)
Frame = +3
Query: 105 LGFNEQELPNLFSILDSDSITTLSTAYPRTSHMLDHMRRVWEIIVDQLPSNGTRNKLSRL 284
+G NE EL ++ S++ + + + V E ++ + G + R+
Sbjct: 292 VGLNEVELASVVSVMGEKELAERIISKDPADPIA-----VIEGLLKLIKETGVK----RI 342
Query: 285 HLHTIGYQIIMTNKHSKFWHSSRSAVAKASLVAHRYTCG-IHNVDIERSKLLMDDSFSIS 461
H HT GY + +T + + H + + A A + G I + R L +
Sbjct: 343 HFHTYGYYLALTREKGE--HVRDALLFSALAAATKAMKGNIEKLSDIREGLAVPIGEQGL 400
Query: 462 EIPNSPRVHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAALLNQLRI 635
E+ F+ D + E+ +L P V K TVG GD ISS+A +++ +
Sbjct: 401 EVEKILEKEFSLRDGIGSIEDYQLTFI--PTKVVKKPKSTVGIGDTISSSAFVSEFSL 456
>sp|Q9V1A6|K6PF_PYRAB ADP-specific phosphofructokinase (ADP-dependent
phosphofructokinase) (ADP-Pfk)
Length = 451
Score = 34.3 bits (77), Expect = 0.34
Identities = 45/179 (25%), Positives = 75/179 (41%), Gaps = 7/179 (3%)
Frame = +3
Query: 105 LGFNEQELPNLFSILDSDSITTLSTAYPRTSH-MLDHMRRVWEIIVDQLPSNGTRNKLSR 281
+G +E E+ L S+L + Y R +L M II+D+L
Sbjct: 285 VGIDEAEIAQLLSVLGYRDLADRIFTYNRLEDSILGGM-----IILDEL-------NFEI 332
Query: 282 LHLHTIGYQIIMTNKHSKFWHSS--RSAVAKASLVAHRYTCGIHNVDIERSKLLMDDSFS 455
L +HTI Y + +T++ + +S +L A R + G DI R + +
Sbjct: 333 LQVHTIYYLMYITHRDNPLSEEELMKSLEFGTTLAAARASLG----DINRP-----EDYE 383
Query: 456 IS-EIPNSPR---VHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAALL 620
I ++P + R V F + + RE ++ V P + + TVG GD IS+ A +
Sbjct: 384 IGLKVPFNERSEYVKLRFEEAKTKLRMREYKVVVIPTRLVPNPVLTVGLGDTISAGAFI 442
>sp|O59355|K6PF_PYRHO ADP-specific phosphofructokinase (ADP-dependent
phosphofructokinase) (ADP-Pfk)
Length = 450
Score = 33.5 bits (75), Expect = 0.57
Identities = 45/182 (24%), Positives = 75/182 (41%), Gaps = 7/182 (3%)
Frame = +3
Query: 105 LGFNEQELPNLFSILDSDSITTLSTAYPRTSH-MLDHMRRVWEIIVDQLPSNGTRNKLSR 281
+G +E E+ + S+L + Y R +L M II+D+L
Sbjct: 284 VGIDEAEIAQILSVLGYRELADRIFTYNRLEDSILGGM-----IILDEL-------NFEI 331
Query: 282 LHLHTIGYQIIMTNKHSKFWHS--SRSAVAKASLVAHRYTCGIHNVDIERSKLLMDDSFS 455
L +HT Y + +T++ + ++S +L A R + G DI D +
Sbjct: 332 LQVHTTYYLMYITHRDNPLSEEELAKSLEFGTTLAAARASLG----DIRGP-----DDYK 382
Query: 456 IS-EIPNSPR---VHFNFTDPVSCWEERELEICVAPVLVCTKVIRTVGGGDNISSAALLN 623
+ ++P + R V F + S RE ++ V P + + TVG GD IS+ A L
Sbjct: 383 VGLKVPFNERSEYVKLRFEEAKSRLRMREYKVVVIPTRLVQNPVLTVGLGDTISAGAFLT 442
Query: 624 QL 629
L
Sbjct: 443 YL 444
>sp|Q5IS37|NTRK3_PANTR NT-3 growth factor receptor precursor (Neurotrophic tyrosine kinase
receptor type 3)
Length = 825
Score = 33.1 bits (74), Expect = 0.75
Identities = 26/76 (34%), Positives = 33/76 (43%)
Frame = +2
Query: 233 HC*SIAIKRN*K*IITPPPTYHWISNNHDK*TFQILAQFKISCC*GKPSCTQIHVWYTQC 412
HC ++ N PPPT HW+ N Q L + KI IHV Y
Sbjct: 319 HCIEFVVRGN------PPPTLHWLHNG------QPLRESKI-----------IHVEY--- 352
Query: 413 GYREVKIVNG*LIFNK 460
Y+E +I G L+FNK
Sbjct: 353 -YQEGEISEGCLLFNK 367
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,952,895
Number of Sequences: 369166
Number of extensions: 1567429
Number of successful extensions: 3247
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3164
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3240
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6267895215
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)