Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00999 (721 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q24318|TDP_DROME Transcription factor dp 47 4e-05 sp|Q14186|TDP1_HUMAN Transcription factor Dp-1 (E2F dimeriz... 40 0.006 sp|Q14188|TDP2_HUMAN Transcription factor Dp-2 (E2F dimeriz... 40 0.008 sp|Q08639|TDP1_MOUSE Transcription factor Dp-1 (E2F dimeriz... 39 0.011 sp|Q64163|TDP2_MOUSE Transcription factor Dp-2 (E2F dimeriz... 39 0.011 sp|Q22703|TDP1_CAEEL Transcription factor dpl-1 39 0.018 sp|Q07283|TRHY_HUMAN Trichohyalin 36 0.091 sp|O35942|NEK2_MOUSE Serine/threonine-protein kinase Nek2 (... 36 0.091 sp|P35732|YKF4_YEAST Hypothetical 84.0 kDa protein in NUP12... 32 2.2 sp|P12393|SPI1_MYXVL Serine proteinase inhibitor 1 (Serpin ... 31 2.9
>sp|Q24318|TDP_DROME Transcription factor dp Length = 445 Score = 47.4 bits (111), Expect = 4e-05 Identities = 23/52 (44%), Positives = 29/52 (55%) Frame = +1 Query: 1 FTFDQPFEMQDEFQTLKQSGFTLRLGTSQCTESQYKRCLELVPNTLRFYVEA 156 F FD+ FEM D+ + LK+ GF L L +CT +R VP L YVEA Sbjct: 334 FKFDKTFEMHDDIEVLKRMGFLLGLDKGECTPENIERVKSWVPPNLAKYVEA 385
>sp|Q14186|TDP1_HUMAN Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1-polypeptide-1) (DRTF1) Length = 410 Score = 40.0 bits (92), Expect = 0.006 Identities = 19/55 (34%), Positives = 26/55 (47%) Frame = +1 Query: 1 FTFDQPFEMQDEFQTLKQSGFTLRLGTSQCTESQYKRCLELVPNTLRFYVEAIYQ 165 F FD FE+ D+ + LK+ G L + C+ K LVP L YV + Q Sbjct: 285 FNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQ 339
>sp|Q14188|TDP2_HUMAN Transcription factor Dp-2 (E2F dimerization partner 2) Length = 446 Score = 39.7 bits (91), Expect = 0.008 Identities = 18/53 (33%), Positives = 27/53 (50%) Frame = +1 Query: 1 FTFDQPFEMQDEFQTLKQSGFTLRLGTSQCTESQYKRCLELVPNTLRFYVEAI 159 F FD FE+ D+ + LK+ G + L + +C+ K LVP L Y+ I Sbjct: 300 FNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDI 352
>sp|Q08639|TDP1_MOUSE Transcription factor Dp-1 (E2F dimerization partner 1) (DRTF1-polypeptide-1) Length = 410 Score = 39.3 bits (90), Expect = 0.011 Identities = 19/55 (34%), Positives = 26/55 (47%) Frame = +1 Query: 1 FTFDQPFEMQDEFQTLKQSGFTLRLGTSQCTESQYKRCLELVPNTLRFYVEAIYQ 165 F FD FE+ D+ + LK+ G L + C+ K LVP L YV + Q Sbjct: 285 FNFDNTFEIHDDIEVLKRMGMACGLESGNCSAEDLKVARSLVPKALEPYVTEMAQ 339
>sp|Q64163|TDP2_MOUSE Transcription factor Dp-2 (E2F dimerization partner 2) (Dp-3) Length = 446 Score = 39.3 bits (90), Expect = 0.011 Identities = 18/53 (33%), Positives = 27/53 (50%) Frame = +1 Query: 1 FTFDQPFEMQDEFQTLKQSGFTLRLGTSQCTESQYKRCLELVPNTLRFYVEAI 159 F FD FE+ D+ + LK+ G + L + +C+ K LVP L Y+ I Sbjct: 300 FNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKIARSLVPKALEGYITDI 352
>sp|Q22703|TDP1_CAEEL Transcription factor dpl-1 Length = 598 Score = 38.5 bits (88), Expect = 0.018 Identities = 18/60 (30%), Positives = 30/60 (50%) Frame = +1 Query: 1 FTFDQPFEMQDEFQTLKQSGFTLRLGTSQCTESQYKRCLELVPNTLRFYVEAIYQQRPAI 180 F+FD+ FE+ D+F+ LK+ L T+ T + K +P + YV+ I R + Sbjct: 243 FSFDKKFEIHDDFEILKKLNLACSLETTNPTAEEVKTAKSFLPTLHQHYVDEIIANRKKV 302
>sp|Q07283|TRHY_HUMAN Trichohyalin Length = 1898 Score = 36.2 bits (82), Expect = 0.091 Identities = 44/146 (30%), Positives = 64/146 (43%), Gaps = 11/146 (7%) Frame = +3 Query: 120 AGAQHSQVLR*SYLPAAPRHRA*FRVPAPQEHGRRCASPLK--QEFVSSEQFRSQLVPAD 293 A A+ S+VL L A RA P QE RR S L+ +E + Q + + D Sbjct: 731 ADARQSKVL----LEAPQAGRA--EAPQEQEEKRRRESELQWQEEERAHRQQQEEEQRRD 784 Query: 294 RRGQPELPEQSQQHFLVRTARVPLHDDRQALRVAEEIQQRLER---------QLGRSLRG 446 Q + E+S++ +AR PL + R+ AEE QQR +R Q GR R Sbjct: 785 FTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRGRQRRE 844 Query: 447 TSSEIQINYEPVTQFQRSQFDELRHE 524 E+Q E +R + +L+ E Sbjct: 845 REKELQFLEEEEQLQRRERAQQLQEE 870
>sp|O35942|NEK2_MOUSE Serine/threonine-protein kinase Nek2 (NimA-related protein kinase 2) Length = 443 Score = 36.2 bits (82), Expect = 0.091 Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 1/67 (1%) Frame = +3 Query: 231 SPLKQEFVSSEQFRSQLVPADRRGQP-ELPEQSQQHFLVRTARVPLHDDRQALRVAEEIQ 407 SPL + V+ EQ R+ R G+P +LP+ S ++ L D QALR E+I Sbjct: 268 SPLIADMVAEEQRRNLERRGRRSGEPSKLPDSSPVLSELKLKESQLQDREQALRAREDIL 327 Query: 408 QRLERQL 428 ++ ER+L Sbjct: 328 EQKEREL 334
>sp|P35732|YKF4_YEAST Hypothetical 84.0 kDa protein in NUP120-CSE4 intergenic region Length = 738 Score = 31.6 bits (70), Expect = 2.2 Identities = 19/77 (24%), Positives = 38/77 (49%) Frame = +3 Query: 303 QPELPEQSQQHFLVRTARVPLHDDRQALRVAEEIQQRLERQLGRSLRGTSSEIQINYEPV 482 QP+ P+Q QQ + + P +Q + ++ QQ ++ Q + E Q++ Sbjct: 395 QPQQPQQPQQPQQQQQPQQPQQPQQQLQQQQQQQQQPVQAQ------AQAQEEQLSQNYY 448 Query: 483 TQFQRSQFDELRHEISQ 533 TQ Q+ Q+ + +H++ Q Sbjct: 449 TQQQQQQYAQQQHQLQQ 465
>sp|P12393|SPI1_MYXVL Serine proteinase inhibitor 1 (Serpin 1) (Serp-1) Length = 369 Score = 31.2 bits (69), Expect = 2.9 Identities = 25/66 (37%), Positives = 30/66 (45%), Gaps = 13/66 (19%) Frame = +1 Query: 1 FTFDQPF---------EMQDEFQTLKQSGFTLRLGTSQCTESQYKR----CLELVPNTLR 141 FT DQPF M ++ TLK FTLR TE YKR L +VP+ L Sbjct: 162 FTTDQPFYSGNVTYKVRMMNKIDTLKTETFTLRNVGYSVTELPYKRRQTAMLLVVPDDLG 221 Query: 142 FYVEAI 159 V A+ Sbjct: 222 EIVRAL 227
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 71,439,546 Number of Sequences: 369166 Number of extensions: 1294248 Number of successful extensions: 3817 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3682 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3815 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 6413660220 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)