Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00984 (1085 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P04190|BLA2_BACCE Beta-lactamase II precursor (Penicilli... 60 8e-09 sp|P14488|BLAB_BACCE Beta-lactamase II precursor (Penicilli... 59 2e-08 sp|Q08889|GLO2_BUCAP Probable hydroxyacylglutathione hydrol... 53 2e-06 sp|P10425|BLA2_BAC17 Beta-lactamase II precursor (Penicilli... 53 2e-06 sp|P25910|BLAB_BACFR Beta-lactamase type II precursor (Peni... 51 7e-06 sp|P57336|GLO2_BUCAI Probable hydroxyacylglutathione hydrol... 49 3e-05 sp|P54435|YRKH_BACSU Hypothetical protein yrkH 48 6e-05 sp|Q89AN4|GLO2_BUCBP Probable hydroxyacylglutathione hydrol... 48 6e-05 sp|P0AC84|GLO2_ECOLI Probable hydroxyacylglutathione hydrol... 47 7e-05 sp|P54553|YQJP_BACSU Hypothetical protein yqjP 47 9e-05
>sp|P04190|BLA2_BACCE Beta-lactamase II precursor (Penicillinase) (Cephalosporinase) Length = 257 Score = 60.5 bits (145), Expect = 8e-09 Identities = 59/226 (26%), Positives = 104/226 (46%), Gaps = 16/226 (7%) Frame = +3 Query: 51 DKTMHK*NIMLPSIPKISQIVPGITRILGMNPSAMTLQGTNSYLIGTNTSKLLIDTSNLH 230 +KT+ K SI ++++ V T + N A+ +N ++ T+ +L+D+S Sbjct: 35 EKTVIKNETGTISISQLNKNVWVHTELGSFNGEAVP---SNGLVLNTSKGLVLVDSS--- 88 Query: 231 QNAYIDNLRQYLIESCENS---TISDIIVTHWHPDHIGGVSDI-------FDLAKSLNWK 380 + D L + LIE E ++D+I+TH H D IGG+ + A + Sbjct: 89 ---WDDKLTKELIEMVEKKFQKRVTDVIITHAHADRIGGIKTLKERGIKAHSTALTAELA 145 Query: 381 KPNVFKYPSLDHSSECNILKSDEVISLSKYGMGTLKVLYT-PGHTDDHICLLLQPENILF 557 K N ++ P D + N+ K+G ++ Y GHT+D+I + L NIL Sbjct: 146 KKNGYEEPLGDLQTVTNL----------KFGNMKVETFYPGKGHTEDNIVVWLPQYNILV 195 Query: 558 SGDLILGNGSTTFENLT-LYMNSLKT-IESI---GNSLSMILPGHG 680 G L+ + N+ Y+N T IE++ +++ ++PGHG Sbjct: 196 GGCLVKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHG 241
>sp|P14488|BLAB_BACCE Beta-lactamase II precursor (Penicillinase) (Cephalosporinase) Length = 256 Score = 58.9 bits (141), Expect = 2e-08 Identities = 53/188 (28%), Positives = 88/188 (46%), Gaps = 17/188 (9%) Frame = +3 Query: 168 TNSYLIGTNTSKLLIDTSNLHQNAYIDNLRQYLIESCENS---TISDIIVTHWHPDHIGG 338 +N ++ T+ +L+D+S + D L + LIE E ++D+I+TH H D IGG Sbjct: 70 SNGLVLNTSKGLVLVDSS------WDDKLTKELIEMVEKKFKKRVTDVIITHAHADRIGG 123 Query: 339 VSDI-------FDLAKSLNWKKPNVFKYPSLDHSSECNILKSDEVISLSKYGMGTLKVLY 497 + + A + K N ++ P D S N+ K+G ++ Y Sbjct: 124 MKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQSVTNL----------KFGNMKVETFY 173 Query: 498 T-PGHTDDHICLLLQPENILFSGDLILGNGSTTFENLT-LYMNSLKT-IESI----GNSL 656 GHT+D+I + L IL G L+ S N+ Y+N T IE++ GN + Sbjct: 174 PGKGHTEDNIVVWLPQYQILAGGCLVKSASSKDLGNVADAYVNEWSTSIENVLKRYGN-I 232 Query: 657 SMILPGHG 680 ++++PGHG Sbjct: 233 NLVVPGHG 240
>sp|Q08889|GLO2_BUCAP Probable hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) Length = 250 Score = 52.8 bits (125), Expect = 2e-06 Identities = 55/195 (28%), Positives = 88/195 (45%), Gaps = 13/195 (6%) Frame = +3 Query: 279 ENSTISDIIVTHWHPDHIGGVSDIFDLAKSLNWKKPNVFKY-PSLDHSSECN-ILKSDEV 452 +N + I++TH H DH+GGV +I + PNV + P + N I+K +V Sbjct: 42 KNWKLIAILLTHNHIDHVGGVEEIIR-------RYPNVTVFGPEETKTRNVNKIVKQGDV 94 Query: 453 ISLSKYGMGTLKVLYTPGHTDDHICLLLQPENILFSGDLILGNG-STTFENLTL------ 611 I L K + V TPGHT H+ L+P +F GD + G F+N Sbjct: 95 IKLLK---SEIHVFLTPGHTLGHVSYYLKP--YIFCGDTLFSGGCGRVFKNKFFDMYQSI 149 Query: 612 -YMNSL--KTIESIGNSLSMILPGHGVEIDQPVSKIKEYLQHRQERIKQVFNALEIS-QW 779 ++ SL KTI + ++ + I KIK+Y + ++ I Q +L +S + Sbjct: 150 NFIKSLPKKTILCCSHEYTLSNLNFAMSILPFDKKIKKYYKKIKKHISQNKTSLPVSLET 209 Query: 780 QSEIEILSKVYSKDI 824 + +I I + K I Sbjct: 210 EKKINIFLRTNEKTI 224
>sp|P10425|BLA2_BAC17 Beta-lactamase II precursor (Penicillinase) Length = 257 Score = 52.8 bits (125), Expect = 2e-06 Identities = 46/189 (24%), Positives = 88/189 (46%), Gaps = 18/189 (9%) Frame = +3 Query: 168 TNSYLIGTNTSKLLIDTSNLHQNAYIDNLRQYLIESCENS---TISDIIVTHWHPDHIGG 338 +N ++ T+ +L+D+S + + L + LIE E ++D+I+TH H D IGG Sbjct: 71 SNGLVLNTSKGLVLVDSS------WDNKLTKELIEMVEKKFQKRVTDVIITHAHADRIGG 124 Query: 339 VSDI-------FDLAKSLNWKKPNVFKYPSLDHSSECNILKSDEVISLSKYGMGTLKVLY 497 ++ + A + K + ++ P D + N+ K+G ++ Y Sbjct: 125 ITALKERGIKAHSTALTAELAKKSGYEEPLGDLQTVTNL----------KFGNTKVETFY 174 Query: 498 T-PGHTDDHICLLLQPENILFSGDLI-------LGNGSTTFENLTLYMNSLKTIESIGNS 653 GHT+D+I + L IL G L+ LGN + + N + S++ + + Sbjct: 175 PGKGHTEDNIVVWLPQYQILAGGCLVKSAEAKNLGNVADAYVN--EWSTSIENMLKRYRN 232 Query: 654 LSMILPGHG 680 +++++PGHG Sbjct: 233 INLVVPGHG 241
>sp|P25910|BLAB_BACFR Beta-lactamase type II precursor (Penicillinase) (Cephalosporinase) (Imipenem-cefoxitin hydrolyzing enzyme) Length = 249 Score = 50.8 bits (120), Expect = 7e-06 Identities = 47/189 (24%), Positives = 82/189 (43%), Gaps = 18/189 (9%) Frame = +3 Query: 168 TNSYLIGTNTSKLLIDTSNLHQNAYIDNLRQYLIESCENSTISDIIVTHWHPDHIGGVSD 347 +N ++ N L+DT +A + L ++ +S ++ ++ I HWH D IGG+ Sbjct: 54 SNGMIVINNHQAALLDTPI--NDAQTEMLVNWVTDSL-HAKVTTFIPNHWHGDCIGGLGY 110 Query: 348 I-------------FDLAKSLNWKKPNVFKYPSLDHSSECNILKSDEVISLSKYGMGTLK 488 + DLAK P +H ++ S + + L Y +G Sbjct: 111 LQRKGVQSYANQMTIDLAKEKGLPVP--------EHGFTDSLTVSLDGMPLQCYYLGG-- 160 Query: 489 VLYTPGHTDDHICLLLQPENILFSGDLILGNGSTTFENL-----TLYMNSLKTIESIGNS 653 GH D+I + L ENILF G ++ N +T+ N+ T + +L +++ S Sbjct: 161 -----GHATDNIVVWLPTENILFGGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPS 215 Query: 654 LSMILPGHG 680 ++PGHG Sbjct: 216 ARYVVPGHG 224
>sp|P57336|GLO2_BUCAI Probable hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX II) Length = 251 Score = 48.5 bits (114), Expect = 3e-05 Identities = 45/162 (27%), Positives = 69/162 (42%), Gaps = 4/162 (2%) Frame = +3 Query: 180 LIGTNTSKLLIDTSNLHQNAYIDNLRQYLIESCENST--ISDIIVTHWHPDHIGGVSDIF 353 L+ T+ S ++ID L + +I+ E + I++TH H DH GG I Sbjct: 17 LLNTSGSCIIIDPG----------LSEPIIQEIERKKWRLRAILLTHNHIDHTGGTRKII 66 Query: 354 DLAKSLNWKKPNVFKYPSLDHSSECNILKSDEVISLSKYGMGTLKVLYTPGHTDDHICLL 533 + ++ P + H + D +I L K V +TPGHT H+ Sbjct: 67 EYFPKISVFGPKETR----QHGVNKIVSHGDRIILLDKI----FYVFFTPGHTSGHVSYY 118 Query: 534 LQPENILFSGDLILGNG-STTFENLTLYM-NSLKTIESIGNS 653 QP +F GD + G F+N L M S+K I S+ +S Sbjct: 119 SQP--YIFCGDTLFSAGCGRVFKNKHLEMYRSIKIISSLPDS 158
>sp|P54435|YRKH_BACSU Hypothetical protein yrkH Length = 295 Score = 47.8 bits (112), Expect = 6e-05 Identities = 47/187 (25%), Positives = 86/187 (45%), Gaps = 9/187 (4%) Frame = +3 Query: 162 QGTNSYLIGTNTSKLLIDTSNLHQNAYIDNLRQYLIESCENSTISDIIVTHWHPDHIGGV 341 +G SY++ +N +ID + + N +ID + + +TI+ + TH H DHI G Sbjct: 49 KGCLSYMVISNGEAAIIDATRM-VNFFIDFAKG------KGATITHVFDTHLHADHISGG 101 Query: 342 SDIFDLAKSLNWKKPNVFKYPSLDHSSECNILKSDEVISLSKYGMGTLKV--LYTPGHTD 515 I + K+ W P + D+ + + +++I G T+K+ +Y+PGHT Sbjct: 102 RVIAEKTKATYWLPPKDAEEVEFDYQP---LEEGNDII----IGNTTIKIQPIYSPGHTI 154 Query: 516 DHICLLLQPENILFSGDLI----LGNGSTTFENLTLYMNSLKTIESIGNSLS---MILPG 674 ++ + L SGD++ +G + KT+ S +LS ++LP Sbjct: 155 GSTSFIVD-DQYLLSGDILFIDSIGRPDLAGMAEDWVGDLRKTLYSRYKALSKDLIVLPA 213 Query: 675 HGVEIDQ 695 H + ID+ Sbjct: 214 HFMIIDE 220
>sp|Q89AN4|GLO2_BUCBP Probable hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) Length = 249 Score = 47.8 bits (112), Expect = 6e-05 Identities = 51/195 (26%), Positives = 83/195 (42%), Gaps = 4/195 (2%) Frame = +3 Query: 300 IIVTHWHPDHIGGVSDIFDLAKSLNWKKPNVFKYPSLD--HSSECNILKSDEVISLSKYG 473 I++TH H DHI GV K+L +K P + Y L+ N++ + I + Sbjct: 49 ILLTHNHLDHIQGV-------KNLLYKYPEISIYGPLETQFCGTKNLIDNRNTIEILN-- 99 Query: 474 MGTLKVLYTPGHTDDHICLLLQPENILFSGDLILGNGSTTFEN--LTLYMNSLKTIESIG 647 ++ TPGHT+ H P LF GD I G +N + NSL+TI + Sbjct: 100 -TKFYIIPTPGHTNGHTAYYCPP--FLFCGDSIFSGGCGRVKNGMMIKMYNSLRTISKLP 156 Query: 648 NSLSMILPGHGVEIDQPVSKIKEYLQHRQERIKQVFNALEISQWQSEIEILSKVYSKDIL 827 N ++I H E + + + + + I +N ++ S+ Q + K+ K Sbjct: 157 ND-TLIYCSH--EYTRSNLEFFKKIFPKNLNILNYYNNIKKSKTQCTLPSTLKIEKK--- 210 Query: 828 ANPVLFMGALKNQHQ 872 NP L + +HQ Sbjct: 211 INPFLQLNNTNLRHQ 225
>sp|P0AC84|GLO2_ECOLI Probable hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) sp|P0AC85|GLO2_ECO57 Probable hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) Length = 251 Score = 47.4 bits (111), Expect = 7e-05 Identities = 49/202 (24%), Positives = 83/202 (41%), Gaps = 23/202 (11%) Frame = +3 Query: 300 IIVTHWHPDHIGGVSDIFDLAKSLNWKKPNVFKY--PSLDHSSECNILKSDEVISLSKYG 473 I +TH H DH+GGV ++ + K P + Y ++K E + + Sbjct: 49 IFLTHHHHDHVGGVKELVE-------KFPQIVVYGPQETQDKGTTQVVKDGETAFVLGH- 100 Query: 474 MGTLKVLYTPGHTDDHICLLLQPENILFSGDLILGNG-STTFENLTLYM-NSLKTIESIG 647 V+ TPGHT HIC +P LF GD + G FE M SLK + ++ Sbjct: 101 --EFSVIATPGHTLGHICYFSKP--YLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALP 156 Query: 648 NSLSM----------------ILPGHGVEIDQPVSKIKEYLQHRQERIKQVF-NALEISQ 776 + + ILP H + I+ K+KE Q + + N +I+ Sbjct: 157 DDTLVCCAHEYTLSNMKFALSILP-HDLSINDYYRKVKELRAKNQITLPVILKNERQINV 215 Query: 777 W--QSEIEILSKVYSKDILANP 836 + +I++++ + + +L P Sbjct: 216 FLRTEDIDLINVINEETLLQQP 237
>sp|P54553|YQJP_BACSU Hypothetical protein yqjP Length = 319 Score = 47.0 bits (110), Expect = 9e-05 Identities = 50/229 (21%), Positives = 95/229 (41%), Gaps = 49/229 (21%) Frame = +3 Query: 285 STISDIIVTHWHPDHIGGVSDIFD--------------LAKS---LNWKKPNVFKY-PSL 410 S I +++TH H DH G+ D+F ++++ ++W+K K P L Sbjct: 58 SDIEQVVLTHHHADH-AGLLDVFSDEIEVIGHTFNEPYISQNQAFMDWQKRFFQKLLPEL 116 Query: 411 ----DHSSECNILKSDEVISLSKY-------GMGT-----LKVLYTPGHTDDHICLLLQP 542 D +++S S ++ GMG VL PGH + HI L + Sbjct: 117 GVPFDTGKAEKLIRSAYAFSCTRSLTKSIREGMGIDGLEGWSVLEMPGHAESHIVLFHEK 176 Query: 543 ENILFSGDLILGN------------GSTTFENLTLYMNSLKTIESIGNSLSMILPGHG-- 680 + GDL+L N G + L Y SL+ + + ++ + PGHG Sbjct: 177 SGRMLGGDLLLANSSSNPILEAPKAGDVRSKPLVDYQRSLRRLSQLDPTI--VFPGHGEP 234 Query: 681 -VEIDQPVSKIKEYLQHRQERIKQVFNALEISQWQSEIEILSKVYSKDI 824 + + K + ++R E ++++ + ++ +Q ++ VY K++ Sbjct: 235 ITSVQALIEKRFDKQRNRTEDVRRMLDEKPMTAFQVCQQLFPAVYEKEL 283
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 114,307,057 Number of Sequences: 369166 Number of extensions: 2300051 Number of successful extensions: 6055 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5807 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6032 length of database: 68,354,980 effective HSP length: 112 effective length of database: 47,664,660 effective search space used: 11868500340 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)